iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096768

Ensembl Protein ID

ENSPFOP00000024375.1

UniProt Accession

A0A096LYY4; A0A096LYY4_POEFO

Genbank Protein ID

ENSPFOP00000024375

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01007589

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000007816.2	ENSPFOT00000023743.1	ENSPFOP00000024375.1
ENSPFOG00000007816.2	ENSPFOT00000008245.2	ENSPFOP00000008233.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-134	448.9	578	910

Active Site

Position(s)	Description	Evidence
880	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++ lk+rl++ef+ E+gld+gGv+re+++llske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+lld 
   Q: 578  PDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVFHGKLLDG 666
           57899***********************************************************************************8 PP
   S: 91   p.lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
             + ++fyk++lgk++sl+d+e+vd+e+y+slk+i+en   d +e  ldl+f+++e+++g+t++++Lkp+G+++ VtneNk+eY++lv+
   Q: 667  SfFIRPFYKMMLGKQISLKDMESVDSEYYNSLKWILEN---DPTE--LDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNENKKEYIDLVI 750
           5279********************************99...6666..7***************************************** PP
   S: 179  eyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqF 267
           ++r+ +++++q++af eGf+e+ip++l+++F+e+elell+cG  ++dv+d++++t yk+gy +++p+iqwFw+v+  +++e+r ++LqF
   Q: 751  QWRFVNRVQKQMNAFLEGFTELIPIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKVVLLMDAEKRIRLLQF 839
           ***************************************************************************************** PP
   S: 268  vTgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           vTg+sr+P++Gfael     p+lf+i++++++d+lP+++TCfn+L+LP Y+s e l+ekLl+A+e+++gFe
   Q: 840  VTGTSRVPMNGFAELYgsngPQLFTIEQWGTPDKLPRAHTCFNRLDLPSYESFEDLREKLLMAVENAQGFE 910
           **********************************************************************8 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MATNYEPIYG LSEDEHETRV LRVKVIAGID LAKKDIIGAS DPYVKLSLYV ADENKELGLV 60
QTKTIKKTLN PKWNEEFYFR VCPQNHRLLF EVFDENRLTR DDFLGQVDVP LSHLPTEDPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAACGA ATTACGAGCC TATATATGGA CTTTCAGAGG ACGAGGTAAG CTTGAATTGT 60
AATTAAGGTG TTATTGAAAT GCAGAATGGA GTCTTTGGGT ATTATGAGGG GCTGGGAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

PRINTS

PR00360--C2DOMAIN

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001314	Ailuropoda melanoleuca	72.12	0.00e+00	1244.00
IUUC-Apl-003893	Anas platyrhynchos	70.69	0.00e+00	1231.00
IUUC-Aca-004744	Anolis carolinensis	67.79	0.00e+00	1180.00
IUUC-Aor-010053	Aspergillus oryzae	58.19	2.00e-101	362.00
IUUC-Ame-010810	Astyanax mexicanus	95.02	0.00e+00	998.00
IUUC-Cfa-021226	Canis familiaris	71.38	0.00e+00	1270.00
IUUC-Cpo-021671	Cavia porcellus	73.21	0.00e+00	1278.00
IUUC-Cho-024832	Choloepus hoffmanni	94.62	0.00e+00	715.00
IUUC-Csv-026098	Ciona savignyi	67.34	0.00e+00	637.00
IUUC-Dre-027770	Danio rerio	95.02	0.00e+00	1009.00
IUUC-Dor-030138	Dipodomys ordii	70.56	0.00e+00	1192.00
IUUC-Dme-032166	Drosophila melanogaster	68.62	0.00e+00	721.00
IUUC-Ete-033145	Echinops telfairi	72.23	0.00e+00	947.00
IUUC-Eeu-035247	Erinaceus europaeus	80.64	0.00e+00	1026.00
IUUC-Fal-037604	Ficedula albicollis	69.87	0.00e+00	1262.00
IUUC-Gmo-039674	Gadus morhua	95.76	0.00e+00	991.00
IUUC-Gga-040703	Gallus gallus	71.20	0.00e+00	1287.00
IUUC-Gac-042020	Gasterosteus aculeatus	97.05	0.00e+00	1001.00
IUUC-Ggo-045332	Gorilla gorilla	72.76	0.00e+00	1251.00
IUUC-Loc-052662	Lepisosteus oculatus	93.00	0.00e+00	975.00
IUUC-Laf-053850	Loxodonta africana	72.73	0.00e+00	1292.00
IUUC-Mpo-057442	Magnaporthe poae	52.36	1.00e-146	514.00
IUUC-Mla-058996	Melampsora laricipopulina	54.45	5.00e-151	528.00
IUUC-Mvi-060395	Microbotryum violaceum	55.03	2.00e-153	536.00
IUUC-Mdo-062173	Monodelphis domestica	69.54	0.00e+00	1273.00
IUUC-Opr-071044	Ochotona princeps	81.95	0.00e+00	1004.00
IUUC-Ont-072044	Oreochromis niloticus	98.53	0.00e+00	1063.00
IUUC-Oan-073032	Ornithorhynchus anatinus	64.89	0.00e+00	974.00
IUUC-Ocu-074160	Oryctolagus cuniculus	72.57	0.00e+00	1275.00
IUUC-Psi-093645	Pelodiscus sinensis	70.71	0.00e+00	1274.00
IUUC-Pma-094364	Petromyzon marinus	81.67	0.00e+00	853.00
IUUC-Pca-100714	Procavia capensis	73.29	0.00e+00	872.00
IUUC-Pva-102354	Pteropus vampyrus	72.20	0.00e+00	1236.00
IUUC-Pgr-103620	Puccinia graminis	53.83	3.00e-149	522.00
IUUC-Ptt-103806	Puccinia triticina	54.46	8.00e-126	444.00
IUUC-Sha-107482	Sarcophilus harrisii	69.33	0.00e+00	1120.00
IUUC-Ssc-115950	Sus scrofa	80.29	0.00e+00	882.00
IUUC-Tgu-117130	Taeniopygia guttata	71.58	0.00e+00	1274.00
IUUC-Tru-118610	Takifugu rubripes	78.22	0.00e+00	1405.00
IUUC-Tsy-119492	Tarsius syrichta	69.44	0.00e+00	1163.00
IUUC-Tni-120113	Tetraodon nigroviridis	71.55	0.00e+00	1248.00
IUUC-Ttr-128235	Tursiops truncatus	80.03	0.00e+00	1021.00
IUUC-Uma-129332	Ustilago maydis	52.99	1.00e-142	500.00
IUUC-Xtr-132859	Xenopus tropicalis	72.16	0.00e+00	1256.00
IUUC-Xma-133797	Xiphophorus maculatus	99.82	0.00e+00	1034.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence