iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106736

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01203807

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000006684.1	ENSSHAT00000007760.1	ENSSHAP00000007697.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	91.94	0.00e+00	1671.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

DFGSLFDLEH DLPDELISSS ELGLTNGGDI NQIQSSLSIA QDAASKHKQL SELLRAGSSP 60
NLNMGVGGPG QGMATQAQQN SPGMGILNSM VKSPMGQAGL TSPNMGVGAS GPNQGPSAQS 120

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Nucleotide Sequence
(Fasta)

CAAAGTGTGG AAAGCTGAAC ATGTTCAGTA GTAAAAACCA TTGCTCTGGG TGTCCTCATT 60
TGCTAAGCCT TAATTTTCTG TTTTTCTCTT CTAGATTTTG GATCCTTGTT TGACTTAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001156	Aegilops tauschii	37.15	4.00e-66	247.00
IUUC-Aml-002027	Ailuropoda melanoleuca	91.93	0.00e+00	1594.00
IUUC-Apl-003917	Anas platyrhynchos	88.76	0.00e+00	1428.00
IUUC-Aca-005040	Anolis carolinensis	88.29	0.00e+00	1546.00
IUUC-Ath-007233	Arabidopsis thaliana	37.63	4.00e-73	270.00
IUUC-Ame-011395	Astyanax mexicanus	88.94	0.00e+00	1462.00
IUUC-Bta-012649	Bos taurus	91.42	0.00e+00	1598.00
IUUC-Bdi-014481	Brachypodium distachyon	39.46	5.00e-70	260.00
IUUC-Bol-016000	Brassica oleracea	38.44	1.00e-72	269.00
IUUC-Bra-018090	Brassica rapa	38.44	7.00e-73	269.00
IUUC-Cel-018691	Caenorhabditis elegans	47.57	0.00e+00	836.00
IUUC-Cja-019649	Callithrix jacchus	94.16	0.00e+00	1598.00
IUUC-Cfa-020764	Canis familiaris	95.15	0.00e+00	1601.00
IUUC-Cpo-022345	Cavia porcellus	82.76	0.00e+00	2617.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	34.59	2.00e-64	241.00
IUUC-Csa-023866	Chlorocebus sabaeus	94.71	0.00e+00	1607.00
IUUC-Cho-024951	Choloepus hoffmanni	93.76	0.00e+00	1189.00
IUUC-Cin-025624	Ciona intestinalis	61.52	0.00e+00	1055.00
IUUC-Csv-026122	Ciona savignyi	64.36	0.00e+00	668.00
IUUC-Dre-028500	Danio rerio	88.16	0.00e+00	1453.00
IUUC-Dno-029638	Dasypus novemcinctus	80.11	0.00e+00	1428.00
IUUC-Dor-030279	Dipodomys ordii	70.93	0.00e+00	1202.00
IUUC-Dme-031716	Drosophila melanogaster	73.39	0.00e+00	776.00
IUUC-Ete-032979	Echinops telfairi	85.58	0.00e+00	1456.00
IUUC-Eca-034048	Equus caballus	95.04	0.00e+00	1603.00
IUUC-Eeu-035154	Erinaceus europaeus	87.64	0.00e+00	1321.00
IUUC-Fca-035891	Felis catus	95.04	0.00e+00	1603.00
IUUC-Fal-037585	Ficedula albicollis	93.22	0.00e+00	1593.00
IUUC-Gmo-039348	Gadus morhua	87.40	0.00e+00	1441.00
IUUC-Gga-040916	Gallus gallus	93.94	0.00e+00	1652.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.60	0.00e+00	1407.00
IUUC-Ggo-045189	Gorilla gorilla	94.82	0.00e+00	1598.00
IUUC-Hsa-046884	Homo sapiens	94.71	0.00e+00	1595.00
IUUC-Hvu-047619	Hordeum vulgare	37.15	4.00e-66	247.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	95.73	0.00e+00	1543.00
IUUC-Loc-052536	Lepisosteus oculatus	86.92	0.00e+00	1437.00
IUUC-Laf-054423	Loxodonta africana	91.73	0.00e+00	1621.00
IUUC-Mcc-054847	Macaca mulatta	94.71	0.00e+00	1607.00
IUUC-Meu-056217	Macropus eugenii	92.14	0.00e+00	1625.00
IUUC-Mtr-058740	Medicago truncatula	37.76	2.00e-66	248.00
IUUC-Mga-059250	Meleagris gallopavo	92.90	0.00e+00	1643.00
IUUC-Mmr-061496	Microcebus murinus	95.15	0.00e+00	1613.00
IUUC-Mdo-062478	Monodelphis domestica	96.90	0.00e+00	1703.00
IUUC-Mmu-063456	Mus musculus	91.31	0.00e+00	1611.00
IUUC-Mac-065060	Musa acuminata	33.11	9.00e-100	358.00
IUUC-Mpu-065963	Mustela putorius furo	91.31	0.00e+00	1613.00
IUUC-Mlu-067185	Myotis lucifugus	94.72	0.00e+00	1615.00
IUUC-Ncr-068795	Neurospora crassa	37.97	1.00e-13	70.50
IUUC-Nle-069907	Nomascus leucogenys	94.60	0.00e+00	1615.00
IUUC-Opr-070324	Ochotona princeps	73.84	0.00e+00	1003.00
IUUC-Ont-072211	Oreochromis niloticus	88.49	0.00e+00	1445.00
IUUC-Oan-073723	Ornithorhynchus anatinus	94.93	0.00e+00	1665.00
IUUC-Ocu-074707	Oryctolagus cuniculus	93.72	0.00e+00	1560.00
IUUC-Oba-075590	Oryza barthii	38.58	3.00e-72	267.00
IUUC-Ogu-078580	Oryza glumaepatula	33.47	5.00e-102	366.00
IUUC-Oin-079283	Oryza indica	38.58	7.00e-72	266.00
IUUC-Olo-080969	Oryza longistaminata	38.58	7.00e-72	266.00
IUUC-Ome-081615	Oryza meridionalis	33.61	1.00e-101	365.00
IUUC-Oni-082636	Oryza nivara	33.61	1.00e-101	365.00
IUUC-Opu-084073	Oryza punctata	38.58	2.00e-72	268.00
IUUC-Oru-084994	Oryza rufipogon	33.61	1.00e-101	365.00
IUUC-Osa-085860	Oryza sativa	41.61	3.00e-61	230.00
IUUC-Ola-086899	Oryzias latipes	77.82	0.00e+00	1373.00
IUUC-Olu-087701	Ostreococcus lucimarinus	34.95	2.00e-61	231.00
IUUC-Oga-088700	Otolemur garnettii	83.97	0.00e+00	2684.00
IUUC-Oar-089787	Ovis aries	92.76	0.00e+00	1600.00
IUUC-Ptr-091620	Pan troglodytes	94.71	0.00e+00	1596.00
IUUC-Pan-092166	Papio anubis	94.71	0.00e+00	1608.00
IUUC-Psi-093992	Pelodiscus sinensis	94.42	0.00e+00	1642.00
IUUC-Pma-094328	Petromyzon marinus	85.33	0.00e+00	991.00
IUUC-Ppa-095569	Physcomitrella patens	37.97	4.00e-70	260.00
IUUC-Pfo-097342	Poecilia formosa	85.16	0.00e+00	1379.00
IUUC-Pab-098235	Pongo abelii	91.93	0.00e+00	1604.00
IUUC-Pop-098947	Populus trichocarpa	39.75	2.00e-72	268.00
IUUC-Pca-100780	Procavia capensis	86.82	0.00e+00	1417.00
IUUC-Ppe-101498	Prunus persica	36.93	5.00e-66	246.00
IUUC-Pva-103071	Pteropus vampyrus	94.71	0.00e+00	1631.00
IUUC-Smo-109420	Selaginella moellendorffii	38.01	4.00e-70	260.00
IUUC-Sit-110128	Setaria italica	37.94	8.00e-71	263.00
IUUC-Stu-112845	Solanum tuberosum	37.92	2.00e-61	230.00
IUUC-Sar-113479	Sorex araneus	64.88	0.00e+00	637.00
IUUC-Sbi-114827	Sorghum bicolor	38.83	3.00e-72	267.00
IUUC-Ssc-116077	Sus scrofa	92.04	0.00e+00	1624.00
IUUC-Tgu-116872	Taeniopygia guttata	93.63	0.00e+00	1592.00
IUUC-Tru-118047	Takifugu rubripes	90.77	0.00e+00	1451.00
IUUC-Tsy-119451	Tarsius syrichta	81.06	0.00e+00	1231.00
IUUC-Tca-121835	Theobroma cacao	38.89	5.00e-72	266.00
IUUC-Tvi-122536	Trichoderma virens	43.04	2.00e-15	77.00
IUUC-Tae-124383	Triticum aestivum	38.23	5.00e-67	249.00
IUUC-Tur-126284	Triticum urartu	37.15	1.00e-66	249.00
IUUC-Tbe-127772	Tupaia belangeri	82.06	0.00e+00	1003.00
IUUC-Ttr-128447	Tursiops truncatus	80.00	0.00e+00	1439.00
IUUC-Vpa-130766	Vicugna pacos	92.65	0.00e+00	1162.00
IUUC-Xtr-131854	Xenopus tropicalis	94.40	0.00e+00	1505.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence