iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090866

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2 variant 1

Genbank Nucleotide ID

AACZ03123420

Gene Name

UBE2V1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000013615.6	ENSPTRT00000025373.5	ENSPTRP00000023422.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UEV	6.60e-68	227.1	4	145
E2/UBC	9.20e-20	70.8	32	138
UBD/UBC-like/UBD_UEV	1.10e-51	174.4	2	139

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UEV

   S: 4    eselkvvvprnfrlleeleegekglgdgtvsygldDgddilllsltgtIigpertayegrIyqlklfvgkkYPekPPtvrfsskinmae 92
           ++++ v+vprnfrlleeleeg+kg+gdgtvs+gl+D++d++l+++tg+Iigp+rt ye+rIy+lk+++g+kYPe+PP+vrf++kinm++
   Q: 4    TTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNG 92
           67899************************************************************************************ PP
   S: 93   vndsnGvvdpralpvLanWkreysievvlvqlkkellskenrklqqPpeGnlf 145
           vn+snGvvdpra++vLa+W+++ysi+vvl++l++ ++sken+kl+qPpeG+++
   Q: 93   VNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCY 145
           ***************************************************98 PP

E2/UBC

   S: 16   gisakpvdesd..ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.Gkv...ClsilkeeekWspalsv 98
           ++s +++d++d  lt+w  +i+Gp++t+Ye+++++l+ie+ ++YP  PP v+f+tki    v+++ G v    +s+l    kW+  +s+
   Q: 32   TVSWGLEDDEDmtLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSnGVVdprAISVL---AKWQNSYSI 117
           456667777776689*****************************************999999988798866668888...5******** PP
   S: 99   esvllsiqsll.aepnpespl 118
           + vl ++ +l+ ++ n++ p+
   Q: 118  KVVLQELRRLMmSKENMKLPQ 138
           *********996667777665 PP

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwllet...YPekPPfv 86
           A++++s++kvp+++       r l++l+e++k+++++t+s++l+D+e+++L+r+tG+i++p+r+i y+++i+++++e+   YPe+PPfv
   Q: 2    AATTGSGVKVPRNF-------RLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTI-YENRIYSLKIECgpkYPEAPPFV 82
           7999**********.......********************************************.*********************** PP
   S: 87   svkekidmntikssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++ki+mn+++ssn++vdp+   a++vL+kW+n++s++v+l++++++++ske++kl++p
   Q: 83   RFVTKINMNGVNSSNGVVDPR---AISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQP 139
           *********************...**********************************98 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY 60
ENRIYSLKIE CGPKYPEAPP FVRFVTKINM NGVNSSNGVV DPRAISVLAK WQNSYSIKVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGTGA AGAAGGGGCC GGCCTTCAAG CAACAGCGAC GCAAGATGGC AGCCACCACG 60
GGCTCGGGTG AGCGGGGGCG CCGGTCCCGG CCGGCCGAGG GGGCATGGGC TTGGGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination

KEGG

ptr:100538342

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000910	Aegilops tauschii	54.23	4.00e-40	156.00
IUUC-Aml-001242	Ailuropoda melanoleuca	99.29	6.00e-74	270.00
IUUC-Atr-003005	Amborella trichopoda	51.75	2.00e-38	150.00
IUUC-Apl-003600	Anas platyrhynchos	100.00	2.00e-73	267.00
IUUC-Aca-005104	Anolis carolinensis	93.88	1.00e-78	284.00
IUUC-Aly-005402	Arabidopsis lyrata	53.47	6.00e-40	155.00
IUUC-Ath-007596	Arabidopsis thaliana	52.74	7.00e-39	152.00
IUUC-Ago-007810	Ashbya gossypii	52.21	2.00e-34	137.00
IUUC-Acl-008375	Aspergillus clavatus	49.28	9.00e-33	132.00
IUUC-Afl-008598	Aspergillus flavus	51.11	2.00e-34	137.00
IUUC-Afu-008838	Aspergillus fumigatus	49.63	3.00e-34	137.00
IUUC-Ang-009631	Aspergillus niger	51.85	6.00e-35	139.00
IUUC-Aor-010051	Aspergillus oryzae	51.11	2.00e-34	137.00
IUUC-Ame-010710	Astyanax mexicanus	89.12	2.00e-76	276.00
IUUC-Bgr-012010	Blumeria graminis	51.45	4.00e-33	133.00
IUUC-Bta-013403	Bos taurus	100.00	1.00e-77	281.00
IUUC-Bci-013649	Botrytis cinerea	51.82	5.00e-33	132.00
IUUC-Bdi-014636	Brachypodium distachyon	53.73	5.00e-38	149.00
IUUC-Bol-015323	Brassica oleracea	53.15	7.00e-41	159.00
IUUC-Bra-018041	Brassica rapa	53.15	7.00e-41	159.00
IUUC-Cel-018398	Caenorhabditis elegans	66.67	5.00e-48	182.00
IUUC-Cja-019316	Callithrix jacchus	100.00	1.00e-77	281.00
IUUC-Cfa-021118	Canis familiaris	100.00	1.00e-73	268.00
IUUC-Cre-022629	Chlamydomonas reinhardtii	49.64	7.00e-38	149.00
IUUC-Csa-024275	Chlorocebus sabaeus	99.29	6.00e-74	270.00
IUUC-Cme-027257	Cyanidioschyzon merolae	55.47	9.00e-29	119.00
IUUC-Dre-028019	Danio rerio	88.44	3.00e-76	276.00
IUUC-Dno-029762	Dasypus novemcinctus	100.00	4.00e-74	269.00
IUUC-Dor-030185	Dipodomys ordii	98.04	3.00e-25	108.00
IUUC-Dme-031635	Drosophila melanogaster	66.90	1.00e-59	221.00
IUUC-Ete-033017	Echinops telfairi	90.78	1.00e-70	259.00
IUUC-Eca-034422	Equus caballus	100.00	5.00e-73	266.00
IUUC-Eeu-035327	Erinaceus europaeus	99.29	2.00e-74	272.00
IUUC-Fal-037350	Ficedula albicollis	96.60	2.00e-74	270.00
IUUC-Fso-038147	Fusarium solani	53.96	3.00e-38	150.00
IUUC-Gmo-039237	Gadus morhua	81.63	9.00e-71	258.00
IUUC-Gga-040746	Gallus gallus	97.16	3.00e-72	263.00
IUUC-Gma-043736	Glycine max	54.29	4.00e-43	166.00
IUUC-Ggo-045491	Gorilla gorilla	97.16	4.00e-70	258.00
IUUC-Hsa-045659	Homo sapiens	100.00	1.00e-77	281.00
IUUC-Hvu-047368	Hordeum vulgare	54.48	3.00e-38	150.00
IUUC-Itr-048139	Ictidomys tridecemlineatus	100.00	2.00e-73	267.00
IUUC-Kpa-049337	Komagataella pastoris	51.11	5.00e-32	129.00
IUUC-Lch-050494	Latimeria chalumnae	87.86	8.00e-73	265.00
IUUC-Lpe-050874	Leersia perrieri	54.48	2.00e-38	150.00
IUUC-Loc-052024	Lepisosteus oculatus	88.65	3.00e-73	268.00
IUUC-Laf-054176	Loxodonta africana	100.00	1.00e-77	281.00
IUUC-Mcc-055788	Macaca mulatta	99.29	6.00e-74	270.00
IUUC-Meu-056842	Macropus eugenii	85.56	1.00e-35	143.00
IUUC-Mor-056915	Magnaporthe oryzae	38.67	3.00e-21	94.40
IUUC-Mpo-057437	Magnaporthe poae	46.71	9.00e-30	122.00
IUUC-Mtr-058655	Medicago truncatula	53.79	5.00e-39	153.00
IUUC-Mga-059951	Meleagris gallopavo	98.58	1.00e-73	267.00
IUUC-Mvi-060260	Microbotryum violaceum	54.01	6.00e-37	145.00
IUUC-Mmr-061374	Microcebus murinus	93.88	1.00e-64	237.00
IUUC-Mmu-063234	Mus musculus	92.91	6.00e-69	254.00
IUUC-Mac-065220	Musa acuminata	51.72	1.00e-39	155.00
IUUC-Mpu-065775	Mustela putorius furo	100.00	1.00e-77	281.00
IUUC-Mlu-067269	Myotis lucifugus	95.21	3.00e-71	260.00
IUUC-Nfi-068400	Neosartorya fischeri	44.21	2.00e-26	110.00
IUUC-Ncr-068946	Neurospora crassa	46.36	1.00e-36	145.00
IUUC-Nle-069245	Nomascus leucogenys	100.00	1.00e-77	281.00
IUUC-Opr-070859	Ochotona princeps	87.23	9.00e-64	236.00
IUUC-Ocu-074447	Oryctolagus cuniculus	97.86	8.00e-73	265.00
IUUC-Oba-075005	Oryza barthii	52.99	1.00e-37	148.00
IUUC-Obr-076191	Oryza brachyantha	53.47	2.00e-40	157.00
IUUC-Ogl-077233	Oryza glaberrima	52.99	1.00e-37	148.00
IUUC-Ogu-078374	Oryza glumaepatula	52.99	1.00e-37	148.00
IUUC-Oin-079721	Oryza indica	52.99	1.00e-37	148.00
IUUC-Olo-080528	Oryza longistaminata	48.63	2.00e-35	140.00
IUUC-Ome-081761	Oryza meridionalis	52.99	8.00e-38	149.00
IUUC-Oni-082346	Oryza nivara	52.99	1.00e-37	148.00
IUUC-Opu-083148	Oryza punctata	52.99	1.00e-37	148.00
IUUC-Oru-084359	Oryza rufipogon	52.99	1.00e-37	148.00
IUUC-Osa-085664	Oryza sativa	52.99	1.00e-37	148.00
IUUC-Olu-087815	Ostreococcus lucimarinus	42.11	3.00e-20	90.50
IUUC-Oga-087972	Otolemur garnettii	100.00	2.00e-73	267.00
IUUC-Oar-090166	Ovis aries	99.29	3.00e-74	271.00
IUUC-Pan-092804	Papio anubis	97.28	3.00e-75	273.00
IUUC-Pma-094142	Petromyzon marinus	85.71	1.00e-21	93.60
IUUC-Ppa-095500	Physcomitrella patens	53.19	4.00e-40	156.00
IUUC-Pab-098403	Pongo abelii	99.29	4.00e-74	271.00
IUUC-Pop-099786	Populus trichocarpa	53.15	5.00e-40	155.00
IUUC-Pca-100723	Procavia capensis	99.29	4.00e-74	271.00
IUUC-Ppe-101725	Prunus persica	55.71	3.00e-40	157.00
IUUC-Pva-102393	Pteropus vampyrus	97.87	1.00e-79	289.00
IUUC-Pgr-103617	Puccinia graminis	53.24	5.00e-32	129.00
IUUC-Rno-106065	Rattus norvegicus	93.88	5.00e-73	266.00
IUUC-Sha-107363	Sarcophilus harrisii	95.92	3.00e-74	270.00
IUUC-Sja-107722	Schizosaccharomyces japonicus	54.01	6.00e-35	139.00
IUUC-Spo-108027	Schizosaccharomyces pombe	51.09	2.00e-33	134.00
IUUC-Ssl-108493	Sclerotinia sclerotiorum	52.82	1.00e-34	138.00
IUUC-Smo-109006	Selaginella moellendorffii	46.72	2.00e-29	120.00
IUUC-Sit-110302	Setaria italica	54.86	7.00e-42	162.00
IUUC-Sly-111205	Solanum lycopersicum	52.45	2.00e-40	157.00
IUUC-Stu-112459	Solanum tuberosum	51.75	5.00e-40	155.00
IUUC-Sar-113197	Sorex araneus	100.00	2.00e-50	192.00
IUUC-Sbi-114210	Sorghum bicolor	54.17	3.00e-41	160.00
IUUC-Sre-114909	Sporisorium reilianum	51.82	9.00e-34	135.00
IUUC-Ssc-115939	Sus scrofa	100.00	1.00e-77	281.00
IUUC-Tgu-117289	Taeniopygia guttata	99.29	3.00e-74	270.00
IUUC-Tsy-119103	Tarsius syrichta	98.92	5.00e-51	193.00
IUUC-Tca-121025	Theobroma cacao	56.43	1.00e-40	159.00
IUUC-Tre-121971	Trichoderma reesei	53.96	5.00e-37	146.00
IUUC-Tae-123220	Triticum aestivum	54.48	3.00e-38	150.00
IUUC-Tur-126236	Triticum urartu	54.01	7.00e-39	152.00
IUUC-Tbe-128105	Tupaia belangeri	96.40	5.00e-77	281.00
IUUC-Ttr-128790	Tursiops truncatus	99.29	4.00e-74	271.00
IUUC-Uma-129419	Ustilago maydis	53.28	1.00e-34	137.00
IUUC-Vda-129776	Verticillium dahliae	52.86	1.00e-36	145.00
IUUC-Vpa-130575	Vicugna pacos	99.28	7.00e-72	263.00
IUUC-Vvi-130831	Vitis vinifera	55.71	4.00e-41	159.00
IUUC-Xtr-132359	Xenopus tropicalis	95.24	4.00e-74	269.00
IUUC-Xma-134032	Xiphophorus maculatus	82.99	9.00e-65	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence