iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-037814

Ensembl Protein ID

FOXG_04228P0

UniProt Accession

A0A0D2XJW2; A0A0D2XJW2_FUSO4

Genbank Protein ID

KNB00796.1

Protein Name

Cell division cycle 20-like protein 1, cofactor-APC complex

Genbank Nucleotide ID

DS231699

Gene Name

FOXG_04228

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_04228	FOXG_04228T0	FOXG_04228P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-24	82.6	149	180
E3 adaptor/Cullin RING/APC_C/CDC20	2.50e-141	470.0	16	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH+ +v++l++   d+ l+sG++D++++vWD 
   Q: 149  GHKQEVCGLKWncEDGQLASGGNDNKLMVWDK 180
           8**********95449***************5 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladleekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltghsa 97
           p+kvldapel+ddfylnL+dW+s n+l v+Lgssvy+w+a+t++v kl+ l ++d+vtsvswi++gt+la+Gt kg v+i+D+e+ +++rt+tgh+a
   Q: 16   PYKVLDAPELADDFYLNLVDWGSANILGVGLGSSVYMWNAQTSKVNKLCTL-DDDTVTSVSWIQKGTHLAIGTGKGLVQIWDAEKARRLRTMTGHIA 111
           79*************************************************.99******************************************* PP
   S: 98   rvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfkehkaavkaiawsPwqksl 194
           rvg+L+Wn+++l+sGsrd+ i hrdvr++++ l++l +h+qevCGlkwn ++ +LasGGnDn+++vwd+ s++Pl kf++h+aavkai+wsP+q++l
   Q: 112  RVGSLAWNTHILTSGSRDRLIYHRDVRAPDQWLRKLVGHKQEVCGLKWNCEDGQLASGGNDNKLMVWDKLSETPLWKFSDHTAAVKAISWSPHQRGL 208
           ************************************************************************************************* PP
   S: 195  LasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDetl 291
           LasGGGtaDr+i f++t++g++++eidtgsqvc+++wsk+s+e+vsthG+++n+i++wkyps+++va+l+gh++Rvl+la+spdg++ivt+agDetl
   Q: 209  LASGGGTADRRIIFHDTVKGSVINEIDTGSQVCNIAWSKNSNEIVSTHGYSQNQIVVWKYPSMTQVASLTGHTYRVLYLAMSPDGRTIVTGAGDETL 305
           ************************************************************************************************* PP
   S: 292  rfwklfdkk 300
           rfw  f ++
   Q: 306  RFWSTFGRR 314
           ****99876 PP

Organism

Fusarium oxysporum

Protein Sequence
(Fasta)

MLLSPRRQPR AVSKVPYKVL DAPELADDFY LNLVDWGSAN ILGVGLGSSV YMWNAQTSKV 60
NKLCTLDDDT VTSVSWIQKG THLAIGTGKG LVQIWDAEKA RRLRTMTGHI ARVGSLAWNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTACTGA GTCCCAGACG TCAGCCCAGA GCTGTCAGTA AGGTTCCTTA CAAGGTTCTC 60
GATGCTCCCG AACTAGCCGA TGACTTTTAC CTTAACTTGG TCGACTGGGG AAGTGCCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR013979--TIF_beta_prop-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF08662--eIF2A
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0051301--P:cell division
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	61.51	3.00e-110	390.00
IUUC-Aml-002003	Ailuropoda melanoleuca	64.17	1.00e-122	431.00
IUUC-Atr-002753	Amborella trichopoda	64.10	7.00e-116	409.00
IUUC-Apl-003212	Anas platyrhynchos	64.29	4.00e-124	436.00
IUUC-Aly-005442	Arabidopsis lyrata	61.75	1.00e-122	431.00
IUUC-Ath-006938	Arabidopsis thaliana	61.63	4.00e-122	429.00
IUUC-Ago-007784	Ashbya gossypii	53.04	6.00e-105	372.00
IUUC-Acl-008269	Aspergillus clavatus	77.84	6.00e-160	555.00
IUUC-Afl-008432	Aspergillus flavus	77.25	2.00e-159	553.00
IUUC-Afu-008829	Aspergillus fumigatus	77.54	3.00e-160	556.00
IUUC-Ani-009471	Aspergillus nidulans	77.54	3.00e-161	560.00
IUUC-Ang-009711	Aspergillus niger	77.84	2.00e-161	560.00
IUUC-Aor-010118	Aspergillus oryzae	77.25	2.00e-159	553.00
IUUC-Ate-010534	Aspergillus terreus	77.54	3.00e-161	560.00
IUUC-Ame-010685	Astyanax mexicanus	64.91	3.00e-125	439.00
IUUC-Bgr-012013	Blumeria graminis	81.85	5.00e-171	592.00
IUUC-Bta-012586	Bos taurus	64.29	6.00e-124	435.00
IUUC-Bci-013807	Botrytis cinerea	85.07	1.00e-168	584.00
IUUC-Bdi-014981	Brachypodium distachyon	66.78	2.00e-123	434.00
IUUC-Bol-016301	Brassica oleracea	62.05	3.00e-122	429.00
IUUC-Bra-017453	Brassica rapa	62.05	3.00e-122	430.00
IUUC-Cel-018472	Caenorhabditis elegans	58.81	5.00e-111	393.00
IUUC-Cja-019929	Callithrix jacchus	64.17	4.00e-123	432.00
IUUC-Cfa-020977	Canis familiaris	64.17	3.00e-123	433.00
IUUC-Cpo-021537	Cavia porcellus	64.29	6.00e-124	435.00
IUUC-Cre-022944	Chlamydomonas reinhardtii	52.81	1.00e-85	308.00
IUUC-Csa-023389	Chlorocebus sabaeus	64.29	3.00e-124	436.00
IUUC-Cin-025327	Ciona intestinalis	59.82	2.00e-117	414.00
IUUC-Csv-025921	Ciona savignyi	60.42	6.00e-117	412.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	92.81	0.00e+00	657.00
IUUC-Cne-026933	Cryptococcus neoformans	65.05	1.00e-130	458.00
IUUC-Cme-027143	Cyanidioschyzon merolae	60.93	1.00e-110	392.00
IUUC-Dre-027860	Danio rerio	64.49	7.00e-124	435.00
IUUC-Dno-029629	Dasypus novemcinctus	62.75	1.00e-110	391.00
IUUC-Dor-030187	Dipodomys ordii	62.31	9.00e-119	418.00
IUUC-Dse-031502	Dothistroma septosporum	69.28	7.00e-131	459.00
IUUC-Dme-031858	Drosophila melanogaster	60.83	3.00e-120	423.00
IUUC-Ete-032562	Echinops telfairi	54.97	1.00e-98	351.00
IUUC-Eca-034210	Equus caballus	64.29	7.00e-124	435.00
IUUC-Fca-035839	Felis catus	64.29	1.00e-123	434.00
IUUC-Fal-036895	Ficedula albicollis	64.29	4.00e-124	436.00
IUUC-Fso-038420	Fusarium solani	99.10	0.00e+00	688.00
IUUC-Gmo-039544	Gadus morhua	64.29	4.00e-123	432.00
IUUC-Ggr-039774	Gaeumannomyces graminis	93.41	0.00e+00	662.00
IUUC-Gga-041025	Gallus gallus	64.60	1.00e-124	437.00
IUUC-Gac-041566	Gasterosteus aculeatus	64.59	2.00e-117	414.00
IUUC-Gma-044388	Glycine max	61.63	1.00e-119	421.00
IUUC-Ggo-045599	Gorilla gorilla	64.38	6.00e-123	432.00
IUUC-Hsa-046695	Homo sapiens	64.17	2.00e-123	433.00
IUUC-Hvu-047486	Hordeum vulgare	62.50	1.00e-102	363.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	63.98	6.00e-124	435.00
IUUC-Kpa-049239	Komagataella pastoris	66.03	1.00e-128	451.00
IUUC-Lch-049827	Latimeria chalumnae	64.80	3.00e-124	436.00
IUUC-Lpe-051568	Leersia perrieri	62.12	2.00e-106	377.00
IUUC-Loc-052240	Lepisosteus oculatus	64.80	5.00e-125	439.00
IUUC-Mcc-055601	Macaca mulatta	64.29	3.00e-124	436.00
IUUC-Meu-056276	Macropus eugenii	59.55	5.00e-109	385.00
IUUC-Mor-057113	Magnaporthe oryzae	92.22	0.00e+00	657.00
IUUC-Mpo-057599	Magnaporthe poae	93.41	0.00e+00	662.00
IUUC-Mtr-057689	Medicago truncatula	65.05	1.00e-119	421.00
IUUC-Mla-059048	Melampsora laricipopulina	63.38	6.00e-113	399.00
IUUC-Mga-060097	Meleagris gallopavo	59.57	1.00e-110	391.00
IUUC-Mvi-060465	Microbotryum violaceum	63.19	4.00e-128	449.00
IUUC-Mmr-061151	Microcebus murinus	55.76	2.00e-97	347.00
IUUC-Mdo-063062	Monodelphis domestica	64.29	4.00e-124	436.00
IUUC-Mmu-063731	Mus musculus	64.29	7.00e-124	435.00
IUUC-Mac-064942	Musa acuminata	64.08	1.00e-121	427.00
IUUC-Mpu-066173	Mustela putorius furo	64.29	5.00e-124	436.00
IUUC-Mlu-068030	Myotis lucifugus	64.17	4.00e-123	433.00
IUUC-Nfi-068536	Neosartorya fischeri	77.54	2.00e-160	556.00
IUUC-Ncr-068734	Neurospora crassa	90.48	3.00e-178	616.00
IUUC-Nle-070163	Nomascus leucogenys	64.29	3.00e-124	437.00
IUUC-Opr-070974	Ochotona princeps	62.07	3.00e-99	352.00
IUUC-Ont-071725	Oreochromis niloticus	64.17	3.00e-124	436.00
IUUC-Oan-073634	Ornithorhynchus anatinus	63.79	4.00e-109	385.00
IUUC-Oba-075417	Oryza barthii	61.77	6.00e-106	375.00
IUUC-Obr-076123	Oryza brachyantha	66.45	5.00e-120	422.00
IUUC-Ogl-077294	Oryza glaberrima	66.12	4.00e-119	419.00
IUUC-Ogu-077996	Oryza glumaepatula	66.12	3.00e-119	420.00
IUUC-Oin-080172	Oryza indica	66.12	6.00e-119	419.00
IUUC-Olo-081068	Oryza longistaminata	66.12	7.00e-119	418.00
IUUC-Ome-081250	Oryza meridionalis	66.12	3.00e-119	419.00
IUUC-Oni-083048	Oryza nivara	66.12	4.00e-119	419.00
IUUC-Opu-083333	Oryza punctata	66.12	5.00e-119	419.00
IUUC-Oru-085001	Oryza rufipogon	66.12	4.00e-119	419.00
IUUC-Osa-086243	Oryza sativa	66.12	4.00e-119	419.00
IUUC-Ola-086983	Oryzias latipes	63.86	3.00e-123	433.00
IUUC-Oga-088911	Otolemur garnettii	64.29	5.00e-124	436.00
IUUC-Oar-089508	Ovis aries	64.29	6.00e-124	435.00
IUUC-Pan-092147	Papio anubis	64.17	2.00e-123	433.00
IUUC-Psi-093702	Pelodiscus sinensis	64.29	5.00e-124	436.00
IUUC-Pma-094581	Petromyzon marinus	63.19	1.00e-119	421.00
IUUC-Pno-095139	Phaeosphaeria nodorum	70.15	3.00e-135	473.00
IUUC-Ppa-095518	Physcomitrella patens	67.10	1.00e-126	444.00
IUUC-Pfo-096991	Poecilia formosa	64.49	8.00e-124	435.00
IUUC-Pop-098924	Populus trichocarpa	65.36	3.00e-116	410.00
IUUC-Pca-100565	Procavia capensis	64.17	4.00e-123	432.00
IUUC-Ppe-101924	Prunus persica	62.35	1.00e-118	418.00
IUUC-Pva-102602	Pteropus vampyrus	63.24	7.00e-118	415.00
IUUC-Pgr-103466	Puccinia graminis	62.96	2.00e-114	404.00
IUUC-Ptt-103888	Puccinia triticina	58.29	5.00e-107	379.00
IUUC-Pte-104097	Pyrenophora teres	71.35	1.00e-148	518.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	64.74	7.00e-128	449.00
IUUC-Rno-105028	Rattus norvegicus	64.29	7.00e-124	435.00
IUUC-Sce-106240	Saccharomyces cerevisiae	52.72	4.00e-103	367.00
IUUC-Sha-106538	Sarcophilus harrisii	56.83	3.00e-110	390.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	60.62	1.00e-119	421.00
IUUC-Spo-108369	Schizosaccharomyces pombe	58.65	3.00e-114	403.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	85.07	2.00e-169	586.00
IUUC-Smo-109041	Selaginella moellendorffii	65.92	2.00e-126	444.00
IUUC-Sit-110550	Setaria italica	64.08	6.00e-121	425.00
IUUC-Sly-111446	Solanum lycopersicum	64.08	9.00e-116	408.00
IUUC-Stu-112491	Solanum tuberosum	64.08	2.00e-115	407.00
IUUC-Sbi-114386	Sorghum bicolor	64.40	3.00e-121	426.00
IUUC-Sre-115222	Sporisorium reilianum	69.84	1.00e-132	464.00
IUUC-Ssc-116171	Sus scrofa	64.29	6.00e-124	435.00
IUUC-Tgu-116878	Taeniopygia guttata	53.57	8.00e-97	345.00
IUUC-Tru-118528	Takifugu rubripes	62.20	4.00e-123	432.00
IUUC-Tni-119863	Tetraodon nigroviridis	64.29	2.00e-123	434.00
IUUC-Tca-121599	Theobroma cacao	62.65	7.00e-117	412.00
IUUC-Tre-122249	Trichoderma reesei	93.73	0.00e+00	660.00
IUUC-Tvi-122675	Trichoderma virens	93.73	0.00e+00	662.00
IUUC-Tae-123489	Triticum aestivum	66.78	3.00e-124	436.00
IUUC-Tur-126545	Triticum urartu	55.70	2.00e-98	350.00
IUUC-Tme-127151	Tuber melanosporum	81.53	9.00e-156	541.00
IUUC-Tbe-128056	Tupaia belangeri	57.59	6.00e-94	335.00
IUUC-Ttr-129055	Tursiops truncatus	64.17	3.00e-123	433.00
IUUC-Uma-129555	Ustilago maydis	69.21	4.00e-131	460.00
IUUC-Vda-130027	Verticillium dahliae	92.22	0.00e+00	656.00
IUUC-Vvi-131748	Vitis vinifera	65.87	2.00e-116	410.00
IUUC-Xtr-132808	Xenopus tropicalis	64.49	4.00e-124	436.00
IUUC-Xma-134279	Xiphophorus maculatus	64.49	5.00e-124	436.00
IUUC-Yli-134584	Yarrowia lipolytica	68.71	7.00e-139	485.00
IUUC-Zma-135640	Zea mays	64.08	5.00e-121	426.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence