iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070163

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01099060

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000002571.2	ENSNLET00000003400.2	ENSNLEP00000003238.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.60e-151	501.5	243	547
E3 adaptor/Cullin RING/DCX/DWD	2.10e-26	90.9	379	409

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 243  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 331
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wnae+lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 332  LSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 420
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 421  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 509
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 510  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 547
           *********************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 379  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 409
           8**********98889**************9 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

GGSGGATAAI LGTAEPGIPS AAAAAGPAGA AEAGGGRCAV PGEAGSAGAS ERRQRARLTL 60
LQAKPCLAMD QDYERRLLRQ IVIQNENTMP RVTEMRRTLT PASSPVSSPS KHGDRFIPSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGGCAGC GGAGGAGCGA CCGCCGCCAT ATTGGGGACC GCGGAGCCCG GGATCCCGTC 60
AGCGGCGGCC GCGGCCGGGC CTGCGGGAGC TGCGGAGGCC GGAGGCGGGC GCTGTGCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	64.19	5.00e-115	408.00
IUUC-Aml-002003	Ailuropoda melanoleuca	94.35	0.00e+00	926.00
IUUC-Atr-002753	Amborella trichopoda	57.43	9.00e-133	467.00
IUUC-Apl-003212	Anas platyrhynchos	97.97	0.00e+00	984.00
IUUC-Aly-005442	Arabidopsis lyrata	57.34	4.00e-139	487.00
IUUC-Ath-006938	Arabidopsis thaliana	57.83	1.00e-137	483.00
IUUC-Ago-007784	Ashbya gossypii	49.42	6.00e-97	348.00
IUUC-Acl-008269	Aspergillus clavatus	49.79	2.00e-133	468.00
IUUC-Afl-008432	Aspergillus flavus	50.63	1.00e-132	466.00
IUUC-Afu-008829	Aspergillus fumigatus	50.62	4.00e-134	471.00
IUUC-Ani-009471	Aspergillus nidulans	49.48	3.00e-132	465.00
IUUC-Ang-009711	Aspergillus niger	51.06	2.00e-131	462.00
IUUC-Aor-010118	Aspergillus oryzae	50.63	1.00e-132	466.00
IUUC-Ate-010534	Aspergillus terreus	50.62	2.00e-132	465.00
IUUC-Ame-011011	Astyanax mexicanus	92.56	0.00e+00	888.00
IUUC-Bgr-012013	Blumeria graminis	50.51	2.00e-131	462.00
IUUC-Bta-012586	Bos taurus	98.99	0.00e+00	1011.00
IUUC-Bci-013807	Botrytis cinerea	51.65	2.00e-126	446.00
IUUC-Bdi-014981	Brachypodium distachyon	70.49	1.00e-129	456.00
IUUC-Bol-016301	Brassica oleracea	57.01	1.00e-137	483.00
IUUC-Bra-017453	Brassica rapa	57.01	7.00e-138	483.00
IUUC-Cel-018472	Caenorhabditis elegans	65.24	3.00e-143	501.00
IUUC-Cja-019929	Callithrix jacchus	99.19	0.00e+00	990.00
IUUC-Cfa-020977	Canis familiaris	98.19	0.00e+00	983.00
IUUC-Cpo-021537	Cavia porcellus	98.78	0.00e+00	1009.00
IUUC-Csa-023389	Chlorocebus sabaeus	100.00	0.00e+00	1021.00
IUUC-Cin-025327	Ciona intestinalis	69.65	0.00e+00	631.00
IUUC-Csv-025921	Ciona savignyi	66.10	0.00e+00	664.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	51.53	7.00e-133	467.00
IUUC-Cne-026933	Cryptococcus neoformans	59.58	4.00e-128	451.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	3.00e-118	419.00
IUUC-Dre-027470	Danio rerio	91.13	0.00e+00	877.00
IUUC-Dno-029629	Dasypus novemcinctus	84.69	0.00e+00	806.00
IUUC-Dor-030187	Dipodomys ordii	87.70	0.00e+00	872.00
IUUC-Dse-031502	Dothistroma septosporum	50.21	6.00e-127	447.00
IUUC-Dme-031858	Drosophila melanogaster	74.44	0.00e+00	684.00
IUUC-Ete-032562	Echinops telfairi	85.60	0.00e+00	831.00
IUUC-Eca-034210	Equus caballus	98.99	0.00e+00	1013.00
IUUC-Fca-035839	Felis catus	93.51	0.00e+00	933.00
IUUC-Fal-036895	Ficedula albicollis	97.77	0.00e+00	981.00
IUUC-Fox-037814	Fusarium oxysporum	64.29	4.00e-124	437.00
IUUC-Fso-038420	Fusarium solani	50.10	2.00e-132	466.00
IUUC-Gmo-039544	Gadus morhua	89.11	0.00e+00	858.00
IUUC-Ggr-039774	Gaeumannomyces graminis	50.92	3.00e-132	465.00
IUUC-Gga-041025	Gallus gallus	97.77	0.00e+00	981.00
IUUC-Gac-041596	Gasterosteus aculeatus	90.32	0.00e+00	869.00
IUUC-Gma-042657	Glycine max	56.85	4.00e-135	474.00
IUUC-Ggo-045599	Gorilla gorilla	99.19	0.00e+00	955.00
IUUC-Hsa-046695	Homo sapiens	99.40	0.00e+00	993.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	8.00e-107	379.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	98.17	0.00e+00	1007.00
IUUC-Kpa-049239	Komagataella pastoris	58.50	2.00e-122	432.00
IUUC-Lch-049827	Latimeria chalumnae	96.35	0.00e+00	931.00
IUUC-Lpe-051568	Leersia perrieri	50.68	2.00e-111	396.00
IUUC-Loc-052856	Lepisosteus oculatus	91.98	0.00e+00	914.00
IUUC-Laf-054321	Loxodonta africana	91.56	2.00e-110	392.00
IUUC-Mcc-055601	Macaca mulatta	100.00	0.00e+00	1021.00
IUUC-Meu-056276	Macropus eugenii	68.35	6.00e-170	590.00
IUUC-Mor-057113	Magnaporthe oryzae	51.13	2.00e-132	466.00
IUUC-Mpo-057599	Magnaporthe poae	51.12	2.00e-132	466.00
IUUC-Mtr-057689	Medicago truncatula	57.11	4.00e-137	481.00
IUUC-Mla-059048	Melampsora laricipopulina	50.10	5.00e-120	424.00
IUUC-Mga-060097	Meleagris gallopavo	91.75	0.00e+00	908.00
IUUC-Mvi-060465	Microbotryum violaceum	51.98	5.00e-131	461.00
IUUC-Mmr-061151	Microcebus murinus	89.52	0.00e+00	856.00
IUUC-Mdo-063062	Monodelphis domestica	97.57	0.00e+00	982.00
IUUC-Mmu-063731	Mus musculus	98.38	0.00e+00	1007.00
IUUC-Mac-065208	Musa acuminata	57.70	1.00e-129	456.00
IUUC-Mpu-066173	Mustela putorius furo	98.58	0.00e+00	1010.00
IUUC-Mlu-068030	Myotis lucifugus	98.39	0.00e+00	984.00
IUUC-Nfi-068536	Neosartorya fischeri	50.62	8.00e-135	473.00
IUUC-Ncr-068734	Neurospora crassa	52.36	5.00e-135	474.00
IUUC-Opr-070974	Ochotona princeps	92.12	2.00e-156	544.00
IUUC-Ont-072507	Oreochromis niloticus	87.07	0.00e+00	881.00
IUUC-Oan-073634	Ornithorhynchus anatinus	99.32	3.00e-175	607.00
IUUC-Oba-075417	Oryza barthii	62.86	2.00e-111	395.00
IUUC-Obr-076123	Oryza brachyantha	69.51	1.00e-126	446.00
IUUC-Ogl-077294	Oryza glaberrima	53.88	1.00e-126	446.00
IUUC-Ogu-077996	Oryza glumaepatula	69.84	2.00e-125	442.00
IUUC-Oin-080172	Oryza indica	70.16	1.00e-126	446.00
IUUC-Olo-081068	Oryza longistaminata	70.16	1.00e-126	445.00
IUUC-Ome-081250	Oryza meridionalis	54.34	9.00e-128	450.00
IUUC-Oni-083048	Oryza nivara	53.88	1.00e-126	446.00
IUUC-Opu-083333	Oryza punctata	54.29	3.00e-127	448.00
IUUC-Oru-085001	Oryza rufipogon	53.88	1.00e-126	446.00
IUUC-Osa-086243	Oryza sativa	53.88	1.00e-126	446.00
IUUC-Ola-087094	Oryzias latipes	89.42	0.00e+00	828.00
IUUC-Oga-088911	Otolemur garnettii	99.39	0.00e+00	1014.00
IUUC-Oar-089508	Ovis aries	98.99	0.00e+00	1011.00
IUUC-Ptr-090967	Pan troglodytes	87.56	0.00e+00	665.00
IUUC-Pan-092147	Papio anubis	99.40	0.00e+00	993.00
IUUC-Psi-093702	Pelodiscus sinensis	97.58	0.00e+00	981.00
IUUC-Pma-094581	Petromyzon marinus	83.86	0.00e+00	799.00
IUUC-Pno-095139	Phaeosphaeria nodorum	59.76	2.00e-113	402.00
IUUC-Ppa-095952	Physcomitrella patens	57.88	4.00e-141	494.00
IUUC-Pfo-096309	Poecilia formosa	90.93	0.00e+00	872.00
IUUC-Pab-098762	Pongo abelii	82.26	0.00e+00	768.00
IUUC-Pop-098924	Populus trichocarpa	57.21	6.00e-133	467.00
IUUC-Pca-100565	Procavia capensis	92.39	0.00e+00	868.00
IUUC-Ppe-101924	Prunus persica	57.34	2.00e-136	479.00
IUUC-Pva-102602	Pteropus vampyrus	96.16	0.00e+00	945.00
IUUC-Pgr-103466	Puccinia graminis	50.86	2.00e-118	419.00
IUUC-Ptt-103888	Puccinia triticina	53.71	1.00e-107	383.00
IUUC-Pte-104097	Pyrenophora teres	49.22	2.00e-129	456.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	45.49	9.00e-112	397.00
IUUC-Rno-105028	Rattus norvegicus	97.97	0.00e+00	980.00
IUUC-Sce-106240	Saccharomyces cerevisiae	38.92	9.00e-96	343.00
IUUC-Sha-107107	Sarcophilus harrisii	83.40	0.00e+00	819.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	48.53	3.00e-115	408.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.73	3.00e-114	404.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	52.49	3.00e-129	455.00
IUUC-Smo-108878	Selaginella moellendorffii	59.06	3.00e-144	504.00
IUUC-Sit-110550	Setaria italica	55.38	8.00e-128	450.00
IUUC-Sly-111446	Solanum lycopersicum	56.07	2.00e-134	472.00
IUUC-Stu-112491	Solanum tuberosum	55.85	9.00e-134	469.00
IUUC-Sar-112962	Sorex araneus	80.53	7.00e-120	422.00
IUUC-Sbi-114489	Sorghum bicolor	54.32	7.00e-124	437.00
IUUC-Sre-115222	Sporisorium reilianum	47.83	2.00e-132	466.00
IUUC-Ssc-116171	Sus scrofa	98.78	0.00e+00	1011.00
IUUC-Tgu-116878	Taeniopygia guttata	86.43	0.00e+00	843.00
IUUC-Tru-118222	Takifugu rubripes	89.78	0.00e+00	862.00
IUUC-Tni-119863	Tetraodon nigroviridis	90.52	0.00e+00	863.00
IUUC-Tca-121599	Theobroma cacao	55.10	4.00e-135	474.00
IUUC-Tre-122249	Trichoderma reesei	48.21	6.00e-135	474.00
IUUC-Tvi-122675	Trichoderma virens	48.57	3.00e-135	475.00
IUUC-Tae-123028	Triticum aestivum	58.59	3.00e-126	445.00
IUUC-Tur-126545	Triticum urartu	59.94	4.00e-104	371.00
IUUC-Tme-127151	Tuber melanosporum	54.77	8.00e-146	510.00
IUUC-Tbe-128056	Tupaia belangeri	89.38	1.00e-168	585.00
IUUC-Ttr-129055	Tursiops truncatus	97.58	0.00e+00	971.00
IUUC-Uma-129555	Ustilago maydis	47.64	8.00e-132	464.00
IUUC-Vda-130027	Verticillium dahliae	51.13	7.00e-134	470.00
IUUC-Vvi-131749	Vitis vinifera	55.53	4.00e-134	471.00
IUUC-Xtr-132808	Xenopus tropicalis	91.68	0.00e+00	925.00
IUUC-Xma-133183	Xiphophorus maculatus	90.93	0.00e+00	872.00
IUUC-Yli-134584	Yarrowia lipolytica	64.55	2.00e-131	462.00
IUUC-Zma-135640	Zea mays	68.04	2.00e-125	442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence