iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011073

Ensembl Protein ID

ENSAMXP00000010449.1

UniProt Accession

W5KS87; W5KS87_ASTMX

Genbank Protein ID

ENSAMXP00000010449

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01109271

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010176.1	ENSAMXT00000010449.1	ENSAMXP00000010449.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-76	257.4	41	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           G++N+g tCY+N++LQ+L+++pe+re+l++ ++++l++e  +     +  +lq+lf+ l+  +++  s+++l+++++++++e  +++q+
   Q: 41   GIRNQGGTCYLNALLQTLLFTPEFREQLFSLERSELEAEG-DAGVRVIPLELQRLFARLLLLDEQTASTTALTDSFGWTNHE--ETSQH 126
           9*****************************9999999876.46677999*******************************98..9**** PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D+qE+ ++l+++le++l                            ++++sli++l++g+l +qi+c+ec+nvs+r+e+fldl++ v+g 
   Q: 127  DVQELNRILFSALESSL--------------------------VGTSGSSLIQELYHGTLVNQITCKECKNVSERQEDFLDLTVCVRGV 189
           *****************..........................789******************************************* PP
   S: 180  eetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           +      l+++L ++f++ee +eg+n y c++c++++ a+k  kl+klP++L++ L Rfsf+ e++ r k ++ ++fpl+++l p+c++
   Q: 190  S-----GLEEALwSMFVEEEVFEGNNLYRCSRCERLVCASKAAKLRKLPPFLTVSLLRFSFDFEKCERYKETSTYSFPLSINLLPYCEQ 273
           *.....9*****999************************************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn....................................................... 301
           ++  ++ + +YeL++v++H+G++ +GHY++y+k+                                                       
   Q: 274  SSLPDS-EFSYELFSVIIHKGGCYGGHYHVYIKDidqlghweapeedvkekekvqvkpqslnefdvtleaedpmaaliaviaqepsgsv 361
           888875.9********************************************************************************* PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 362  mldqlgqklmgrigsswnkkfrkqygpiskflqsrsdvfllvsngsrvtlnpkytlthshnngqemaeeqqgmgpdmglevevgiepds 450
           ***********************************************************************************999999 PP
   S: 302  ...............ekgk..WllfdDskVtevkeeevleetg..staYvlfYkr 337
                          +  +  W+ ++Ds+Vt++ke++++++ +  ++aY+lfY++
   Q: 451  elgavsdigngaepeS--GyhWFDLNDSTVTPIKEQDIKKQFKgkESAYMLFYRK 503
           9999999887776422..257*******************8889*********97 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MFGDLFEQDE EGLGDSGAGV HTGGGKEREP QPPRGPIQLS GIRNQGGTCY LNALLQTLLF 60
TPEFREQLFS LERSELEAEG DAGVRVIPLE LQRLFARLLL LDEQTASTTA LTDSFGWTNH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGCCTAG CGGTCTAGCT GCTTGTCAAA CTACAACTAC CACAATGCAT TGCAACACTG 60
CTTCCTCCAG GAGAAACATG GCGGCGCTCT GAACAGCAGC GACACTCAGA TTTAATTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	47.50	0.00e+00	999.00
IUUC-Apl-004105	Anas platyrhynchos	49.22	0.00e+00	1137.00
IUUC-Aca-004715	Anolis carolinensis	48.27	0.00e+00	1080.00
IUUC-Bta-012487	Bos taurus	47.66	0.00e+00	1062.00
IUUC-Cja-018937	Callithrix jacchus	47.16	0.00e+00	1051.00
IUUC-Cfa-020645	Canis familiaris	42.06	3.00e-154	539.00
IUUC-Cpo-022160	Cavia porcellus	46.78	0.00e+00	1066.00
IUUC-Csa-023078	Chlorocebus sabaeus	48.25	0.00e+00	1089.00
IUUC-Cho-025013	Choloepus hoffmanni	74.30	2.00e-99	357.00
IUUC-Csv-026193	Ciona savignyi	56.96	2.00e-59	222.00
IUUC-Dre-027416	Danio rerio	63.03	0.00e+00	1490.00
IUUC-Dno-029639	Dasypus novemcinctus	44.55	0.00e+00	843.00
IUUC-Dor-030624	Dipodomys ordii	66.56	1.00e-111	398.00
IUUC-Ete-032626	Echinops telfairi	38.36	1.00e-105	378.00
IUUC-Eca-034208	Equus caballus	47.62	0.00e+00	1066.00
IUUC-Fca-036006	Felis catus	64.75	2.00e-136	478.00
IUUC-Fal-036925	Ficedula albicollis	48.20	0.00e+00	1050.00
IUUC-Gmo-038597	Gadus morhua	56.93	0.00e+00	1187.00
IUUC-Gga-041171	Gallus gallus	49.53	0.00e+00	1127.00
IUUC-Gac-041362	Gasterosteus aculeatus	57.94	0.00e+00	1221.00
IUUC-Ggo-045069	Gorilla gorilla	47.56	0.00e+00	967.00
IUUC-Hsa-046715	Homo sapiens	48.08	0.00e+00	1062.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	47.30	0.00e+00	1013.00
IUUC-Lch-050182	Latimeria chalumnae	46.93	0.00e+00	983.00
IUUC-Loc-052705	Lepisosteus oculatus	56.68	0.00e+00	1372.00
IUUC-Laf-054132	Loxodonta africana	47.10	0.00e+00	1048.00
IUUC-Mcc-055734	Macaca mulatta	48.48	0.00e+00	1088.00
IUUC-Meu-056135	Macropus eugenii	75.76	2.00e-99	357.00
IUUC-Mga-060092	Meleagris gallopavo	49.65	0.00e+00	1108.00
IUUC-Mmr-061546	Microcebus murinus	45.44	0.00e+00	983.00
IUUC-Mdo-061935	Monodelphis domestica	46.64	0.00e+00	1058.00
IUUC-Mmu-063630	Mus musculus	46.64	0.00e+00	1050.00
IUUC-Mpu-066579	Mustela putorius furo	46.69	0.00e+00	1080.00
IUUC-Mlu-068034	Myotis lucifugus	46.72	0.00e+00	1032.00
IUUC-Nle-069082	Nomascus leucogenys	44.23	0.00e+00	826.00
IUUC-Opr-070953	Ochotona princeps	39.94	2.00e-126	447.00
IUUC-Ont-072435	Oreochromis niloticus	57.98	0.00e+00	1375.00
IUUC-Oan-073339	Ornithorhynchus anatinus	47.96	0.00e+00	1071.00
IUUC-Ocu-073760	Oryctolagus cuniculus	48.12	0.00e+00	1071.00
IUUC-Ola-087015	Oryzias latipes	57.03	0.00e+00	1164.00
IUUC-Oga-088960	Otolemur garnettii	47.76	0.00e+00	1056.00
IUUC-Oar-089853	Ovis aries	47.78	0.00e+00	1058.00
IUUC-Ptr-091093	Pan troglodytes	48.05	0.00e+00	1062.00
IUUC-Pan-091962	Papio anubis	47.66	0.00e+00	1072.00
IUUC-Psi-093691	Pelodiscus sinensis	47.85	0.00e+00	1103.00
IUUC-Pma-094428	Petromyzon marinus	58.89	6.00e-78	283.00
IUUC-Pfo-096983	Poecilia formosa	58.07	0.00e+00	1283.00
IUUC-Pab-097860	Pongo abelii	47.70	0.00e+00	983.00
IUUC-Pca-100514	Procavia capensis	51.58	5.00e-115	409.00
IUUC-Pva-102771	Pteropus vampyrus	46.28	0.00e+00	984.00
IUUC-Rno-105405	Rattus norvegicus	46.38	0.00e+00	1039.00
IUUC-Sha-107376	Sarcophilus harrisii	46.53	0.00e+00	999.00
IUUC-Ssc-115819	Sus scrofa	39.45	2.00e-177	616.00
IUUC-Tgu-117262	Taeniopygia guttata	48.68	0.00e+00	1123.00
IUUC-Tru-117601	Takifugu rubripes	57.19	0.00e+00	1358.00
IUUC-Tsy-118996	Tarsius syrichta	35.17	5.00e-136	479.00
IUUC-Tni-120682	Tetraodon nigroviridis	53.34	0.00e+00	632.00
IUUC-Tbe-127616	Tupaia belangeri	36.36	3.00e-93	337.00
IUUC-Ttr-129075	Tursiops truncatus	45.80	0.00e+00	976.00
IUUC-Vpa-130108	Vicugna pacos	48.07	0.00e+00	965.00
IUUC-Xtr-132623	Xenopus tropicalis	45.97	0.00e+00	1006.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence