iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023662

Ensembl Protein ID

ENSCSAP00000009352.1

UniProt Accession

A0A0D9RL63; A0A0D9RL63_CHLSB

Genbank Protein ID

ENSCSAP00000009352

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01160704

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000013210.1	ENSCSAT00000011273.1	ENSCSAP00000009352.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	2.90e-26	91.1	454	513

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let++vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q+++l+k++++++d++++s
   Q: 454  QEEDLETMTVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFEDGGRQS 513
           79********************************************************98 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPSEST GNGPPHLAHP NLDTFTPEEL LQQMKELLTE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERQFFETQS KEAKERLMAL SHENEKLKEE LGKLRGKSER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCATC AACCTCTCAG CTGCCTCACT GAAAAGGGGG ACAGCCCCAG TGAAAGCACA 60
GGAAATGGAC CCCCCCATCT GGCCCACCCA AACCTGGACA CGTTCACCCC GGAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	82.61	0.00e+00	802.00
IUUC-Apl-003812	Anas platyrhynchos	56.63	3.00e-153	535.00
IUUC-Aca-004625	Anolis carolinensis	56.13	5.00e-150	524.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.00e-02	33.50
IUUC-Ame-011116	Astyanax mexicanus	37.99	8.00e-73	268.00
IUUC-Bta-013240	Bos taurus	84.11	0.00e+00	909.00
IUUC-Cja-019911	Callithrix jacchus	94.97	0.00e+00	989.00
IUUC-Cfa-020330	Canis familiaris	85.52	0.00e+00	851.00
IUUC-Cpo-021753	Cavia porcellus	81.79	0.00e+00	827.00
IUUC-Cho-024574	Choloepus hoffmanni	68.43	2.00e-130	458.00
IUUC-Dre-027720	Danio rerio	41.17	1.00e-92	333.00
IUUC-Dno-029079	Dasypus novemcinctus	80.52	0.00e+00	777.00
IUUC-Dor-030890	Dipodomys ordii	81.52	0.00e+00	842.00
IUUC-Dme-032072	Drosophila melanogaster	26.73	2.00e-03	37.00
IUUC-Ete-032568	Echinops telfairi	82.44	0.00e+00	756.00
IUUC-Eca-033528	Equus caballus	84.77	0.00e+00	858.00
IUUC-Eeu-035219	Erinaceus europaeus	75.82	0.00e+00	825.00
IUUC-Fca-035852	Felis catus	84.63	0.00e+00	853.00
IUUC-Fal-036862	Ficedula albicollis	58.82	2.00e-149	522.00
IUUC-Gmo-038735	Gadus morhua	40.95	2.00e-79	289.00
IUUC-Gga-040939	Gallus gallus	57.89	4.00e-154	537.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.00	2.00e-98	353.00
IUUC-Ggo-045034	Gorilla gorilla	86.14	0.00e+00	918.00
IUUC-Hsa-046624	Homo sapiens	96.53	0.00e+00	1033.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	79.04	0.00e+00	826.00
IUUC-Lch-049720	Latimeria chalumnae	49.87	1.00e-82	300.00
IUUC-Loc-052185	Lepisosteus oculatus	46.91	4.00e-108	385.00
IUUC-Laf-054079	Loxodonta africana	83.00	0.00e+00	831.00
IUUC-Mcc-055674	Macaca mulatta	98.09	0.00e+00	995.00
IUUC-Meu-056769	Macropus eugenii	55.42	7.00e-76	278.00
IUUC-Mga-060203	Meleagris gallopavo	58.03	1.00e-145	509.00
IUUC-Mmr-061492	Microcebus murinus	87.41	0.00e+00	861.00
IUUC-Mdo-063051	Monodelphis domestica	75.47	0.00e+00	797.00
IUUC-Mmu-063409	Mus musculus	77.83	0.00e+00	867.00
IUUC-Mpu-065907	Mustela putorius furo	78.79	0.00e+00	830.00
IUUC-Mlu-066957	Myotis lucifugus	83.62	0.00e+00	796.00
IUUC-Nle-069973	Nomascus leucogenys	96.53	0.00e+00	1023.00
IUUC-Opr-071049	Ochotona princeps	79.62	0.00e+00	755.00
IUUC-Ont-071915	Oreochromis niloticus	44.28	2.00e-95	342.00
IUUC-Oan-072965	Ornithorhynchus anatinus	73.37	0.00e+00	773.00
IUUC-Ocu-074029	Oryctolagus cuniculus	76.99	0.00e+00	703.00
IUUC-Ola-087019	Oryzias latipes	42.88	1.00e-93	337.00
IUUC-Oga-088613	Otolemur garnettii	88.47	0.00e+00	908.00
IUUC-Oar-090386	Ovis aries	83.59	0.00e+00	901.00
IUUC-Ptr-091619	Pan troglodytes	96.36	0.00e+00	1030.00
IUUC-Pan-092178	Papio anubis	97.76	0.00e+00	997.00
IUUC-Psi-093214	Pelodiscus sinensis	63.73	4.00e-171	594.00
IUUC-Pfo-096901	Poecilia formosa	41.61	5.00e-87	315.00
IUUC-Pab-097560	Pongo abelii	87.35	0.00e+00	889.00
IUUC-Pca-100853	Procavia capensis	75.90	5.00e-128	451.00
IUUC-Pva-102255	Pteropus vampyrus	84.11	0.00e+00	798.00
IUUC-Rno-105812	Rattus norvegicus	80.24	0.00e+00	865.00
IUUC-Sha-107225	Sarcophilus harrisii	80.75	3.00e-159	554.00
IUUC-Sar-113736	Sorex araneus	75.68	1.00e-133	469.00
IUUC-Ssc-115422	Sus scrofa	84.48	0.00e+00	887.00
IUUC-Tgu-116924	Taeniopygia guttata	59.67	2.00e-151	528.00
IUUC-Tru-117695	Takifugu rubripes	38.79	2.00e-90	326.00
IUUC-Tsy-119090	Tarsius syrichta	87.15	4.00e-160	557.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.53	4.00e-94	338.00
IUUC-Tbe-127970	Tupaia belangeri	69.60	0.00e+00	677.00
IUUC-Ttr-129244	Tursiops truncatus	83.94	0.00e+00	835.00
IUUC-Vpa-130313	Vicugna pacos	82.73	0.00e+00	803.00
IUUC-Xtr-132115	Xenopus tropicalis	45.07	7.00e-102	364.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence