iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090123

Ensembl Protein ID

ENSOARP00000019970.1

UniProt Accession

W5QB75; W5QB75_SHEEP

Genbank Protein ID

ENSOARP00000019970

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01090913

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018596.1	ENSOART00000020245.1	ENSOARP00000019970.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-26	90.8	909	943
UBD/Beta-Prp	5.00e-52	177.1	863	1078

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v+c++ f ++tl vs+s D+t+++WDl +g
   Q: 909  GHTGEVRCVEvFaQGTLAVSASKDHTLRLWDLLSG 943
           8********977988****************9776 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           ++l g+ +++ta+ +s ++k+l+ g + +++ vwd++  + vh+l gh+ +v++++++++g   vs+s+d t+r+wdl +gq+  + 
   Q: 863  ATLTGCHKGITAMAWSLEEKLLLVGTQEGMVAVWDMEEQQAVHILPGHTGEVRCVEVFAQGTLAVSASKDHTLRLWDLLSGQEKFTi 949
           689999999999999999999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
                ++++++ +++++v++ ++++ s+s  ++v  W+l+t++ + +  g+  d+  ++++  ++  l+++s+ g + lw+  tg+ 
   Q: 950  wdggSKDPTESQTWSLHVDEAKKVVYSAS-GSKVSAWNLETAEQIFHILGDASDPWVCTAVLASQATLLTVSRGGMISLWSSATGTL 1035
           99999999999999999999666655555.578999999999999999999999999999999999999999999999999999998 PP
   S: 215  vrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsg 254
            r+++  +    +  + v + +++  +v+gss gsi++  ++ +
   Q: 1036 HRRQRLSSikedTLACGVSV-QKQRMMVTGSSTGSISLVSSEGD 1078
           76666544444244444444.59999999999999988655555 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MDAEREALQS TAYPEVQTFC QKHGLMFEVV DLWWGIRNTE ATNPLTTEIC LEELDRCREI 60
SIGPAFVALV GDQYGPCPVP TRIEEKEWEA LKAQLTARPH DLELVARSFW RDENAVPPAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATGGATGC AGAGAGGGAA GCCCTACAGA GCACCGCCTA CCCTGAAGTG CAGACATTCT 60
GCCAGAAGCA CGGCCTGATG TTCGAGGTAA CGACCCACCC TCCCCCGCTC ACTGTCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027417--P-loop_NTPase
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	86.45	0.00e+00	2695.00
IUUC-Apl-003467	Anas platyrhynchos	61.37	4.00e-83	300.00
IUUC-Ame-011400	Astyanax mexicanus	36.31	0.00e+00	967.00
IUUC-Bta-013223	Bos taurus	95.80	0.00e+00	2597.00
IUUC-Cel-018404	Caenorhabditis elegans	29.82	3.00e-101	363.00
IUUC-Cja-018773	Callithrix jacchus	80.00	0.00e+00	1535.00
IUUC-Cfa-020334	Canis familiaris	86.34	0.00e+00	2691.00
IUUC-Cpo-022316	Cavia porcellus	66.04	0.00e+00	1901.00
IUUC-Csa-023631	Chlorocebus sabaeus	81.78	0.00e+00	2527.00
IUUC-Cin-025646	Ciona intestinalis	33.79	4.00e-138	485.00
IUUC-Csv-026191	Ciona savignyi	25.69	4.00e-24	105.00
IUUC-Dre-028241	Danio rerio	35.44	0.00e+00	921.00
IUUC-Dno-029990	Dasypus novemcinctus	81.76	0.00e+00	724.00
IUUC-Dor-030869	Dipodomys ordii	60.06	4.00e-168	585.00
IUUC-Ete-033059	Echinops telfairi	82.63	0.00e+00	842.00
IUUC-Eca-033718	Equus caballus	81.50	0.00e+00	2508.00
IUUC-Fca-035748	Felis catus	84.42	0.00e+00	2407.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.50	0.00e+00	737.00
IUUC-Ggo-044551	Gorilla gorilla	78.62	0.00e+00	2429.00
IUUC-Hsa-046787	Homo sapiens	81.11	0.00e+00	2537.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	83.18	0.00e+00	1082.00
IUUC-Kpa-049302	Komagataella pastoris	38.24	3.00e-10	60.50
IUUC-Lch-049578	Latimeria chalumnae	47.88	0.00e+00	1422.00
IUUC-Loc-052039	Lepisosteus oculatus	41.12	0.00e+00	1203.00
IUUC-Laf-054240	Loxodonta africana	81.74	0.00e+00	2594.00
IUUC-Mcc-054657	Macaca mulatta	74.43	0.00e+00	2180.00
IUUC-Meu-056591	Macropus eugenii	62.78	0.00e+00	1149.00
IUUC-Mmr-061577	Microcebus murinus	78.37	0.00e+00	2394.00
IUUC-Mdo-062895	Monodelphis domestica	61.76	0.00e+00	1774.00
IUUC-Mmu-063866	Mus musculus	76.49	0.00e+00	2329.00
IUUC-Mpu-066510	Mustela putorius furo	84.92	0.00e+00	2693.00
IUUC-Mlu-067855	Myotis lucifugus	84.66	0.00e+00	2569.00
IUUC-Nle-069557	Nomascus leucogenys	77.11	0.00e+00	2329.00
IUUC-Opr-071196	Ochotona princeps	60.49	1.00e-175	610.00
IUUC-Ont-072070	Oreochromis niloticus	35.30	0.00e+00	798.00
IUUC-Oan-073437	Ornithorhynchus anatinus	56.70	0.00e+00	1223.00
IUUC-Ocu-074941	Oryctolagus cuniculus	78.18	7.00e-40	156.00
IUUC-Ola-086624	Oryzias latipes	33.55	0.00e+00	684.00
IUUC-Oga-088313	Otolemur garnettii	82.04	0.00e+00	2315.00
IUUC-Ptr-090552	Pan troglodytes	81.96	0.00e+00	1102.00
IUUC-Psi-093963	Pelodiscus sinensis	53.77	0.00e+00	1575.00
IUUC-Pfo-096197	Poecilia formosa	34.44	0.00e+00	793.00
IUUC-Pab-097755	Pongo abelii	79.11	0.00e+00	905.00
IUUC-Pca-100809	Procavia capensis	78.08	0.00e+00	1185.00
IUUC-Pva-102554	Pteropus vampyrus	81.60	0.00e+00	2243.00
IUUC-Rno-105174	Rattus norvegicus	69.78	0.00e+00	2062.00
IUUC-Sha-107304	Sarcophilus harrisii	61.38	0.00e+00	1976.00
IUUC-Sar-113168	Sorex araneus	69.68	0.00e+00	899.00
IUUC-Tru-118251	Takifugu rubripes	35.52	0.00e+00	639.00
IUUC-Tsy-119276	Tarsius syrichta	78.99	3.00e-118	420.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence