iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035585

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02184302

Gene Name

VPS18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000014720.3	ENSFCAT00000014724.3	ENSFCAP00000013657.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.10e-06	26.5	853	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp......CgHvfhadCl.qkw.pglknssskefr........................................ 41
           Ca+C  df   pl+++      CgH+fhadCl q++ pgl+  ++k++r                                        
   Q: 853  CATC--DF---PLLNRpfylflCGHMFHADCLlQAVrPGLP--AYKQARleelqrklgaapaptkgsarakeaeggaaaggpsreqlka 934
           9***..99...66555666668*********9788887777..8888877777777777777778888888888888888888888888 PP
   S: 42   .........CPlC 45
                    C++C
   Q: 935  dldelvaaeCVYC 947
           8888888888887 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MASILDEYED SLSRSAVLQP GCPSVGIPHS GYVNAQLEKE VPIFTKQRID FTPSERITSL 60
VVSCNQLCMS LGKDTLLRID LGKANEPNHV ELGRKDDARV HKMFLDHTGC HLLIALSSTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGAGTCAG CTGAGCCGCT GGGGCGAGGT TGGGATCTTC TGGGATCTGC AAAAGGAAAC 60
CAGTGATCTT TTGGGGGTGG GAGCGGGGTG CAGGACTGCA CCAGGTTCAA GGGAGAGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000547--Clathrin_H-chain/VPS_repeat
IPR007810--Pep3_Vps18
IPR011990--TPR-like_helical_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50236--CHCR

Pfam

PF00637--Clathrin
PF05131--Pep3_Vps18

Gene Ontology

GO:0005884--C:actin filament
GO:0030123--C:AP-3 adaptor complex
GO:0033263--C:CORVET complex
GO:0005769--C:early endosome
GO:0005768--C:endosome
GO:0030897--C:HOPS complex
GO:0005770--C:late endosome
GO:0005765--C:lysosomal membrane
GO:0030674--F:protein binding, bridging
GO:0007032--P:endosome organization
GO:0008333--P:endosome to lysosome transport
GO:0006886--P:intracellular protein transport
GO:0007040--P:lysosome organization
GO:0035542--P:regulation of SNARE complex assembly
GO:0006904--P:vesicle docking involved in exocytosis
GO:0046718--P:viral entry into host cell

KEGG

fca:101087236

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000419	Aegilops tauschii	31.97	2.00e-108	387.00
IUUC-Aml-001240	Ailuropoda melanoleuca	98.46	0.00e+00	1900.00
IUUC-Atr-003125	Amborella trichopoda	32.87	2.00e-122	433.00
IUUC-Apl-004181	Anas platyrhynchos	72.48	0.00e+00	1478.00
IUUC-Aca-004437	Anolis carolinensis	72.18	0.00e+00	1456.00
IUUC-Aly-006046	Arabidopsis lyrata	33.57	6.00e-134	471.00
IUUC-Ath-006932	Arabidopsis thaliana	33.61	2.00e-133	469.00
IUUC-Ago-007800	Ashbya gossypii	23.28	1.00e-56	214.00
IUUC-Acl-008035	Aspergillus clavatus	31.15	6.00e-110	392.00
IUUC-Afl-008714	Aspergillus flavus	30.96	4.00e-108	385.00
IUUC-Afu-009063	Aspergillus fumigatus	32.02	2.00e-111	396.00
IUUC-Ani-009384	Aspergillus nidulans	32.18	2.00e-114	406.00
IUUC-Ang-009507	Aspergillus niger	32.32	2.00e-111	397.00
IUUC-Aor-010094	Aspergillus oryzae	30.96	1.00e-107	384.00
IUUC-Ate-010421	Aspergillus terreus	31.57	1.00e-96	347.00
IUUC-Ame-011797	Astyanax mexicanus	65.44	0.00e+00	1297.00
IUUC-Bgr-012107	Blumeria graminis	31.95	1.00e-110	394.00
IUUC-Bta-012339	Bos taurus	97.74	0.00e+00	1898.00
IUUC-Bci-013895	Botrytis cinerea	32.97	8.00e-120	424.00
IUUC-Bdi-014554	Brachypodium distachyon	33.43	1.00e-126	447.00
IUUC-Bol-015270	Brassica oleracea	33.61	4.00e-135	476.00
IUUC-Bra-017424	Brassica rapa	33.47	2.00e-129	457.00
IUUC-Cel-018455	Caenorhabditis elegans	25.69	3.00e-85	310.00
IUUC-Cja-019629	Callithrix jacchus	96.40	0.00e+00	1880.00
IUUC-Cfa-020425	Canis familiaris	98.56	0.00e+00	1898.00
IUUC-Cpo-021349	Cavia porcellus	96.20	0.00e+00	1851.00
IUUC-Cre-022799	Chlamydomonas reinhardtii	29.82	2.00e-27	118.00
IUUC-Csa-023559	Chlorocebus sabaeus	97.02	0.00e+00	1888.00
IUUC-Cho-024862	Choloepus hoffmanni	89.11	0.00e+00	1394.00
IUUC-Cin-025599	Ciona intestinalis	41.70	1.00e-176	613.00
IUUC-Csv-026152	Ciona savignyi	42.45	0.00e+00	759.00
IUUC-Cgl-026551	Colletotrichum gloeosporioides	32.09	3.00e-112	399.00
IUUC-Cne-026907	Cryptococcus neoformans	31.35	1.00e-111	398.00
IUUC-Dre-027747	Danio rerio	65.50	0.00e+00	1339.00
IUUC-Dno-029668	Dasypus novemcinctus	97.23	0.00e+00	1872.00
IUUC-Dor-030404	Dipodomys ordii	90.44	0.00e+00	1746.00
IUUC-Dse-031345	Dothistroma septosporum	33.48	4.00e-122	432.00
IUUC-Dme-031711	Drosophila melanogaster	33.91	1.00e-145	510.00
IUUC-Ete-032308	Echinops telfairi	90.73	0.00e+00	909.00
IUUC-Eca-033637	Equus caballus	98.46	0.00e+00	1910.00
IUUC-Eeu-035151	Erinaceus europaeus	96.50	0.00e+00	1392.00
IUUC-Fal-037122	Ficedula albicollis	71.79	0.00e+00	1472.00
IUUC-Fox-038030	Fusarium oxysporum	33.64	7.00e-121	428.00
IUUC-Fso-038426	Fusarium solani	33.57	5.00e-126	445.00
IUUC-Gmo-038784	Gadus morhua	66.02	0.00e+00	1301.00
IUUC-Ggr-039973	Gaeumannomyces graminis	34.05	5.00e-122	432.00
IUUC-Gga-040692	Gallus gallus	73.72	0.00e+00	1500.00
IUUC-Gac-041868	Gasterosteus aculeatus	64.42	0.00e+00	1298.00
IUUC-Gma-044274	Glycine max	34.56	3.00e-136	479.00
IUUC-Ggo-045053	Gorilla gorilla	97.02	0.00e+00	1871.00
IUUC-Hsa-046635	Homo sapiens	97.23	0.00e+00	1874.00
IUUC-Hvu-047361	Hordeum vulgare	33.09	6.00e-126	445.00
IUUC-Itr-048868	Ictidomys tridecemlineatus	97.53	0.00e+00	1873.00
IUUC-Kpa-049270	Komagataella pastoris	23.79	2.00e-77	283.00
IUUC-Lch-050188	Latimeria chalumnae	68.19	0.00e+00	1216.00
IUUC-Lpe-051026	Leersia perrieri	34.55	2.00e-130	460.00
IUUC-Loc-051821	Lepisosteus oculatus	67.11	0.00e+00	1332.00
IUUC-Lma-053178	Leptosphaeria maculans	34.46	7.00e-101	361.00
IUUC-Laf-053552	Loxodonta africana	97.33	0.00e+00	1876.00
IUUC-Mcc-054667	Macaca mulatta	97.12	0.00e+00	1871.00
IUUC-Meu-056422	Macropus eugenii	92.37	0.00e+00	860.00
IUUC-Mor-056981	Magnaporthe oryzae	33.40	2.00e-120	426.00
IUUC-Mtr-058703	Medicago truncatula	34.42	2.00e-133	469.00
IUUC-Mla-059088	Melampsora laricipopulina	34.82	4.00e-93	335.00
IUUC-Mga-059798	Meleagris gallopavo	73.41	0.00e+00	1496.00
IUUC-Mvi-060404	Microbotryum violaceum	33.90	1.00e-121	431.00
IUUC-Mmr-061630	Microcebus murinus	98.15	0.00e+00	1890.00
IUUC-Mdo-062354	Monodelphis domestica	92.81	0.00e+00	1821.00
IUUC-Mmu-063199	Mus musculus	95.79	0.00e+00	1868.00
IUUC-Mac-065595	Musa acuminata	35.44	9.00e-113	400.00
IUUC-Mpu-066596	Mustela putorius furo	97.43	0.00e+00	1902.00
IUUC-Mlu-067455	Myotis lucifugus	97.64	0.00e+00	1879.00
IUUC-Nfi-068565	Neosartorya fischeri	32.48	1.00e-113	404.00
IUUC-Ncr-068748	Neurospora crassa	33.17	1.00e-125	444.00
IUUC-Nle-068979	Nomascus leucogenys	96.97	0.00e+00	1681.00
IUUC-Opr-070711	Ochotona princeps	95.38	0.00e+00	1852.00
IUUC-Ont-072603	Oreochromis niloticus	65.11	0.00e+00	1316.00
IUUC-Oan-073136	Ornithorhynchus anatinus	84.73	0.00e+00	816.00
IUUC-Ocu-074496	Oryctolagus cuniculus	97.02	0.00e+00	1875.00
IUUC-Oba-075933	Oryza barthii	33.44	2.00e-111	397.00
IUUC-Obr-076290	Oryza brachyantha	33.98	9.00e-132	464.00
IUUC-Ogu-078728	Oryza glumaepatula	33.44	1.00e-111	397.00
IUUC-Oin-079954	Oryza indica	33.47	9.00e-123	434.00
IUUC-Olo-081033	Oryza longistaminata	32.24	1.00e-105	377.00
IUUC-Ome-081797	Oryza meridionalis	33.41	4.00e-118	419.00
IUUC-Oni-082802	Oryza nivara	33.44	1.00e-111	397.00
IUUC-Opu-083595	Oryza punctata	35.45	3.00e-131	462.00
IUUC-Oru-084199	Oryza rufipogon	33.44	1.00e-111	397.00
IUUC-Osa-085349	Oryza sativa	33.98	6.00e-131	461.00
IUUC-Ola-087482	Oryzias latipes	65.31	0.00e+00	1308.00
IUUC-Olu-087797	Ostreococcus lucimarinus	25.11	4.00e-64	239.00
IUUC-Oga-088817	Otolemur garnettii	97.12	0.00e+00	1895.00
IUUC-Oar-090350	Ovis aries	95.28	0.00e+00	1459.00
IUUC-Ptr-090999	Pan troglodytes	96.92	0.00e+00	1870.00
IUUC-Pan-092704	Papio anubis	97.12	0.00e+00	1871.00
IUUC-Psi-093529	Pelodiscus sinensis	73.72	0.00e+00	1476.00
IUUC-Pma-094400	Petromyzon marinus	55.91	0.00e+00	1084.00
IUUC-Pno-094875	Phaeosphaeria nodorum	31.90	6.00e-119	422.00
IUUC-Ppa-095231	Physcomitrella patens	33.81	1.00e-130	461.00
IUUC-Pfo-096967	Poecilia formosa	65.01	0.00e+00	1310.00
IUUC-Pab-098300	Pongo abelii	96.92	0.00e+00	1869.00
IUUC-Pop-098966	Populus trichocarpa	34.27	8.00e-139	488.00
IUUC-Pca-100643	Procavia capensis	95.74	0.00e+00	1772.00
IUUC-Ppe-101589	Prunus persica	33.74	2.00e-135	476.00
IUUC-Pva-102766	Pteropus vampyrus	97.33	0.00e+00	1837.00
IUUC-Pgr-103330	Puccinia graminis	30.56	3.00e-108	386.00
IUUC-Ptt-103809	Puccinia triticina	32.13	6.00e-91	329.00
IUUC-Pte-104319	Pyrenophora teres	31.91	7.00e-117	415.00
IUUC-Pyt-104798	Pyrenophora triticirepentis	30.74	5.00e-105	375.00
IUUC-Rno-105817	Rattus norvegicus	95.17	0.00e+00	1859.00
IUUC-Sce-106255	Saccharomyces cerevisiae	23.52	6.00e-44	172.00
IUUC-Sha-107479	Sarcophilus harrisii	93.17	0.00e+00	1815.00
IUUC-Sja-107976	Schizosaccharomyces japonicus	24.94	1.00e-68	254.00
IUUC-Spo-108146	Schizosaccharomyces pombe	26.25	6.00e-71	262.00
IUUC-Ssl-108663	Sclerotinia sclerotiorum	33.75	6.00e-110	392.00
IUUC-Smo-109585	Selaginella moellendorffii	34.40	5.00e-122	432.00
IUUC-Sit-110275	Setaria italica	34.70	6.00e-130	458.00
IUUC-Sly-111073	Solanum lycopersicum	34.71	7.00e-135	474.00
IUUC-Stu-112392	Solanum tuberosum	28.74	7.00e-14	70.50
IUUC-Sar-113718	Sorex araneus	93.53	0.00e+00	1795.00
IUUC-Sbi-114080	Sorghum bicolor	34.70	7.00e-135	474.00
IUUC-Sre-115160	Sporisorium reilianum	31.54	1.00e-122	434.00
IUUC-Ssc-115997	Sus scrofa	97.33	0.00e+00	1887.00
IUUC-Tgu-116904	Taeniopygia guttata	72.75	0.00e+00	1328.00
IUUC-Tru-117946	Takifugu rubripes	64.29	0.00e+00	1307.00
IUUC-Tni-119692	Tetraodon nigroviridis	64.60	0.00e+00	1303.00
IUUC-Tca-121455	Theobroma cacao	33.64	2.00e-136	480.00
IUUC-Tre-122128	Trichoderma reesei	31.98	6.00e-122	431.00
IUUC-Tvi-122657	Trichoderma virens	32.62	7.00e-123	435.00
IUUC-Tae-125953	Triticum aestivum	33.88	8.00e-127	447.00
IUUC-Tur-126110	Triticum urartu	30.64	3.00e-94	340.00
IUUC-Tme-127173	Tuber melanosporum	30.43	2.00e-101	363.00
IUUC-Ttr-128420	Tursiops truncatus	97.53	0.00e+00	1881.00
IUUC-Uma-129580	Ustilago maydis	31.44	1.00e-122	434.00
IUUC-Vda-129790	Verticillium dahliae	31.09	1.00e-110	394.00
IUUC-Vvi-131095	Vitis vinifera	33.16	7.00e-132	464.00
IUUC-Xtr-131906	Xenopus tropicalis	68.86	0.00e+00	1367.00
IUUC-Xma-134197	Xiphophorus maculatus	65.31	0.00e+00	1310.00
IUUC-Yli-134617	Yarrowia lipolytica	28.23	1.00e-96	347.00
IUUC-Zma-134979	Zea mays	32.37	3.00e-102	366.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence