iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053795

UUCD1 version

UUC-LoA-00717

Ensembl Protein ID

ENSLAFP00000018903.1

UniProt Accession

G3TTJ5; G3TTJ5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003046.3	ENSLAFT00000027538.1	ENSLAFP00000018903.1
ENSLAFG00000003046.3	ENSLAFT00000003047.3	ENSLAFP00000002541.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-12	48.1	1123	1156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t +   d t+ l+sG+ Dg i +WD+ tg
   Q: 1123 GHSGAITTVYI-DqTMvLASGGQDGAICLWDVLTG 1156
           8********88.446648*************9887 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MTLTERLREK ISQAFYNHGL LCASYPIPII LFTGLCILAC CYPLLKLPLP GTGPVEFTTP 60
MKDYSPPPVD SGHKQGDPSD QPEWYVGAPV AYIQQIFVKS SVSPWHKNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGA CTGAAAGGCT GCGTGAGAAG ATATCTCAGG CCTTCTACAA CCATGGGCTG 60
CTCTGCGCAT CCTACCCCAT CCCCATCATC CTCTTCACGG GGCTCTGCAT CTTAGCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	94.74	0.00e+00	1099.00
IUUC-Apl-003294	Anas platyrhynchos	76.53	0.00e+00	1724.00
IUUC-Aca-004424	Anolis carolinensis	68.77	0.00e+00	1496.00
IUUC-Bta-013478	Bos taurus	91.45	0.00e+00	2063.00
IUUC-Cel-018160	Caenorhabditis elegans	29.73	9.00e-67	248.00
IUUC-Cja-019123	Callithrix jacchus	89.67	0.00e+00	2017.00
IUUC-Cfa-021082	Canis familiaris	90.83	0.00e+00	1996.00
IUUC-Cpo-022477	Cavia porcellus	84.16	0.00e+00	1865.00
IUUC-Csa-023176	Chlorocebus sabaeus	89.35	0.00e+00	2010.00
IUUC-Cin-025490	Ciona intestinalis	36.77	5.00e-91	329.00
IUUC-Csv-026115	Ciona savignyi	37.30	1.00e-133	471.00
IUUC-Dre-028008	Danio rerio	67.90	0.00e+00	1558.00
IUUC-Dno-028887	Dasypus novemcinctus	91.76	0.00e+00	1218.00
IUUC-Dor-030467	Dipodomys ordii	93.47	0.00e+00	885.00
IUUC-Dme-032087	Drosophila melanogaster	33.37	6.00e-113	402.00
IUUC-Ete-032372	Echinops telfairi	79.74	0.00e+00	1709.00
IUUC-Eca-033896	Equus caballus	92.22	0.00e+00	2143.00
IUUC-Eeu-035099	Erinaceus europaeus	83.91	0.00e+00	1211.00
IUUC-Fca-035616	Felis catus	86.58	0.00e+00	1923.00
IUUC-Fal-037231	Ficedula albicollis	73.98	0.00e+00	1667.00
IUUC-Gmo-039439	Gadus morhua	74.09	0.00e+00	679.00
IUUC-Gac-041516	Gasterosteus aculeatus	66.54	0.00e+00	1507.00
IUUC-Hsa-046674	Homo sapiens	92.23	0.00e+00	2122.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	91.30	0.00e+00	2097.00
IUUC-Lch-049689	Latimeria chalumnae	69.95	0.00e+00	1653.00
IUUC-Loc-052417	Lepisosteus oculatus	53.57	3.00e-139	488.00
IUUC-Mcc-055502	Macaca mulatta	92.69	0.00e+00	2128.00
IUUC-Mga-059805	Meleagris gallopavo	76.81	0.00e+00	1734.00
IUUC-Mmr-060997	Microcebus murinus	91.61	0.00e+00	2138.00
IUUC-Mdo-062940	Monodelphis domestica	81.19	0.00e+00	1842.00
IUUC-Mmu-063255	Mus musculus	90.20	0.00e+00	2055.00
IUUC-Mpu-066158	Mustela putorius furo	91.29	0.00e+00	2067.00
IUUC-Mlu-067201	Myotis lucifugus	86.69	0.00e+00	1980.00
IUUC-Nle-069145	Nomascus leucogenys	93.52	0.00e+00	1352.00
IUUC-Opr-070797	Ochotona princeps	85.39	0.00e+00	1897.00
IUUC-Ont-071553	Oreochromis niloticus	66.67	0.00e+00	1525.00
IUUC-Ocu-074598	Oryctolagus cuniculus	91.52	0.00e+00	2057.00
IUUC-Ola-086650	Oryzias latipes	84.23	2.00e-112	397.00
IUUC-Oar-089287	Ovis aries	85.71	0.00e+00	1117.00
IUUC-Pan-092004	Papio anubis	92.48	0.00e+00	2086.00
IUUC-Psi-093028	Pelodiscus sinensis	71.57	0.00e+00	1528.00
IUUC-Pma-094145	Petromyzon marinus	55.05	0.00e+00	811.00
IUUC-Pfo-096320	Poecilia formosa	66.18	0.00e+00	1528.00
IUUC-Pab-097862	Pongo abelii	92.53	0.00e+00	2132.00
IUUC-Pca-100862	Procavia capensis	82.18	0.00e+00	1711.00
IUUC-Pva-103050	Pteropus vampyrus	90.94	0.00e+00	1318.00
IUUC-Rno-105852	Rattus norvegicus	90.98	0.00e+00	2083.00
IUUC-Sha-107312	Sarcophilus harrisii	81.73	0.00e+00	1880.00
IUUC-Sar-113311	Sorex araneus	87.01	0.00e+00	801.00
IUUC-Ssc-116356	Sus scrofa	91.45	0.00e+00	2121.00
IUUC-Tgu-116896	Taeniopygia guttata	61.23	1.00e-159	557.00
IUUC-Tru-118197	Takifugu rubripes	67.05	0.00e+00	1533.00
IUUC-Tni-119823	Tetraodon nigroviridis	64.74	0.00e+00	1511.00
IUUC-Ttr-129164	Tursiops truncatus	92.31	0.00e+00	2088.00
IUUC-Xtr-132819	Xenopus tropicalis	68.86	0.00e+00	1605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence