iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009290

Ensembl Protein ID

CADANIAP00001628

UniProt Accession

C8VU45; C8VU45_EMENI

Genbank Protein ID

CBF88323.1

Protein Name

SCF ubiquitin ligase complex subunit CulA, putative (AFU_orthologue AFUA_1G12960)

Genbank Nucleotide ID

BN001308

Gene Name

ANIA_01019

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00001628	CADANIAT00001628	CADANIAP00001628

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.10e-181	602.3	30	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 9    ilrqesv.kkeyeelytavynlclsk................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlr 84
           +  ++ v  k+y+ lytav+n+c+s+                +g++lY+kl e+l  +++ v+ +   ++de+lL +y+reW+++++++k+++
   Q: 30   VKLEDGVdMKNYMALYTAVHNFCTSHkavsgqaiqaqrgahlLGEELYRKLGEYLSRHLEWVHGESMGHTDEALLSFYIREWQRYTTAAKYIN 122
           345788999***************999****************************************************************** PP
   S: 85   kifayldrtyvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......laiyk 165
           ++f+yl+r++vk+     +k+v++v++  l +w+++++ +++++++ ++lkl+e++R+ge+++++ ++++v s+v+L+l++       l+iy+
   Q: 123  HLFRYLNRHWVKReidegKKNVYDVYTQHLVKWKEDFFLKVHEKVMGAVLKLVEKQRNGETIEQSRIKSIVDSFVSLGLDEtdptkstLEIYR 215
           ****************9999************************************************************************* PP
   S: 166  esFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrm 258
             F  +fleat+ +y+ es +f++ n+v eY+kk+e rl+ee+ r+  yl++   + L++++  +l++ h e l +e++ ll++++++dl+rm
   Q: 216  YYFQRPFLEATRIYYEDESRQFVADNSVVEYMKKAEIRLEEEKARVGLYLNNDISKDLTSTCLDVLVTAHSELLRDEFQPLLDNERQDDLARM 308
           ********************************************************************************************* PP
   S: 259  ykLlsrvlngleellkeleshikeqgkaalt...aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka..a 346
           y+Llsr+++gl++l+ ++e+h++ +g+ a++   ae  + +pk+yV  ll+++ ++++lv+eaFn + +F+ +ld+a+++fvn+n++ k   +
   Q: 309  YRLLSRIKDGLDPLRTKFEAHVRRAGLSAVEkvaAEGDSFEPKMYVDALLSVHTRYHSLVKEAFNGESEFVRSLDNACREFVNRNKICKSgsT 401
           *******************************76566666699***********************************************999* PP
   S: 347  kspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           k+pEllA+y D+lL+++sk ++e ele++l ++++vfkyi++kdvF+k+Y k+LakRL++  s+s++aE s+i+kLke+cg+e+t+kL+rMfq
   Q: 402  KTPELLAKYTDSLLKRGSKAAEESELEEMLVQIMTVFKYIEDKDVFQKFYSKMLAKRLVHVSSVSDDAETSMISKLKEACGFEYTNKLQRMFQ 494
           ********************************************************************************************* PP
   S: 440  dlkvSedlnrqFk.....eekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelk 527
           d+++S+dln  +k     +  +++  ++ v+   ++L +g+Wp ++   ++  P+e+ kt e+f++fY +kh+gRkL+W+++l+++elka++ 
   Q: 495  DIQISKDLNSSYKdwlekSFLDDDDRKKLVDSHFQILGTGFWPLTAPSTSFLAPPEIVKTSERFQKFYCDKHNGRKLTWLWQLCKGELKANYI 587
           *************88876556777788999999************777889***************************************997 PP
   S: 528  kg...kyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           k+   +y++ Vst+Qm +LL+fn+s+++++ +++kat l +e L   l+ +++ k  vl+ +pe+++   +++fs+N +f
   Q: 588  KNtkvPYTFLVSTYQMGILLLFNESDTLTYSDIQKATTLTPEILDPNLSIFLKAK--VLNISPEGSKPGPDSTFSLNYNF 665
           77778************************************************88..********************998 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MAPLMPQAPH KDDLEETWVF LENGINNVMV KLEDGVDMKN YMALYTAVHN FCTSHKAVSG 60
QAIQAQRGAH LLGEELYRKL GEYLSRHLEW VHGESMGHTD EALLSFYIRE WQRYTTAAKY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATACTTTTCT GGCTTTTTCT CCCAACCTTG CCCCTGCCTC ATACTCTGGA AGCCGGCTTA 60
TAGAAATCTT CTCCTATTCG TTTGGTCTGC TTTTGCGCAA CGTCCTTCTC TCGACTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016874--F:ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000358	Aegilops tauschii	30.58	5.00e-96	343.00
IUUC-Aml-002277	Ailuropoda melanoleuca	46.64	0.00e+00	671.00
IUUC-Apl-003503	Anas platyrhynchos	46.30	1.00e-154	538.00
IUUC-Aca-005030	Anolis carolinensis	42.37	1.00e-145	508.00
IUUC-Ago-007977	Ashbya gossypii	34.29	2.00e-132	464.00
IUUC-Acl-008190	Aspergillus clavatus	85.36	0.00e+00	1300.00
IUUC-Afl-008542	Aspergillus flavus	78.17	0.00e+00	1033.00
IUUC-Afu-009007	Aspergillus fumigatus	83.80	0.00e+00	1217.00
IUUC-Ang-009600	Aspergillus niger	85.95	0.00e+00	1275.00
IUUC-Aor-009978	Aspergillus oryzae	78.43	0.00e+00	1154.00
IUUC-Ate-010584	Aspergillus terreus	86.14	0.00e+00	1311.00
IUUC-Ame-011861	Astyanax mexicanus	46.68	0.00e+00	656.00
IUUC-Bgr-012209	Blumeria graminis	65.23	0.00e+00	983.00
IUUC-Bta-012878	Bos taurus	46.77	0.00e+00	668.00
IUUC-Bci-013941	Botrytis cinerea	68.10	0.00e+00	1089.00
IUUC-Bdi-014686	Brachypodium distachyon	31.72	2.00e-98	351.00
IUUC-Cel-018294	Caenorhabditis elegans	39.48	4.00e-155	540.00
IUUC-Cja-018965	Callithrix jacchus	45.15	0.00e+00	641.00
IUUC-Cfa-020671	Canis familiaris	46.77	0.00e+00	668.00
IUUC-Cpo-021762	Cavia porcellus	46.89	0.00e+00	672.00
IUUC-Cre-022585	Chlamydomonas reinhardtii	32.60	4.00e-96	343.00
IUUC-Csa-023873	Chlorocebus sabaeus	46.89	0.00e+00	672.00
IUUC-Cin-025547	Ciona intestinalis	43.61	8.00e-178	615.00
IUUC-Csv-026083	Ciona savignyi	44.01	0.00e+00	642.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	65.20	0.00e+00	1019.00
IUUC-Cne-026919	Cryptococcus neoformans	47.59	0.00e+00	689.00
IUUC-Dre-027875	Danio rerio	46.71	0.00e+00	658.00
IUUC-Dno-028931	Dasypus novemcinctus	46.89	0.00e+00	665.00
IUUC-Dor-030846	Dipodomys ordii	50.96	6.00e-140	489.00
IUUC-Dse-031472	Dothistroma septosporum	64.29	0.00e+00	993.00
IUUC-Dme-031793	Drosophila melanogaster	43.81	8.00e-177	612.00
IUUC-Ete-033112	Echinops telfairi	44.48	4.00e-72	264.00
IUUC-Eca-034309	Equus caballus	46.77	0.00e+00	668.00
IUUC-Eeu-034450	Erinaceus europaeus	41.63	3.00e-87	314.00
IUUC-Fca-036330	Felis catus	45.78	0.00e+00	647.00
IUUC-Fal-036899	Ficedula albicollis	46.22	2.00e-160	557.00
IUUC-Fox-037705	Fusarium oxysporum	62.47	0.00e+00	951.00
IUUC-Fso-038367	Fusarium solani	64.04	0.00e+00	990.00
IUUC-Gmo-038708	Gadus morhua	46.09	0.00e+00	659.00
IUUC-Ggr-039917	Gaeumannomyces graminis	64.92	0.00e+00	1006.00
IUUC-Gga-041038	Gallus gallus	46.89	0.00e+00	671.00
IUUC-Gac-041820	Gasterosteus aculeatus	46.34	0.00e+00	682.00
IUUC-Ggo-045154	Gorilla gorilla	41.14	6.00e-131	459.00
IUUC-Hsa-046034	Homo sapiens	46.89	0.00e+00	672.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	46.89	0.00e+00	671.00
IUUC-Kpa-049231	Komagataella pastoris	37.90	1.00e-146	511.00
IUUC-Lch-049673	Latimeria chalumnae	46.64	0.00e+00	664.00
IUUC-Loc-052490	Lepisosteus oculatus	46.96	0.00e+00	660.00
IUUC-Lma-053191	Leptosphaeria maculans	65.48	0.00e+00	1034.00
IUUC-Laf-054582	Loxodonta africana	46.89	0.00e+00	671.00
IUUC-Mcc-055162	Macaca mulatta	46.64	0.00e+00	660.00
IUUC-Meu-055904	Macropus eugenii	45.56	6.00e-71	260.00
IUUC-Mor-057035	Magnaporthe oryzae	64.00	0.00e+00	973.00
IUUC-Mpo-057555	Magnaporthe poae	65.18	0.00e+00	1011.00
IUUC-Mla-059021	Melampsora laricipopulina	51.29	0.00e+00	749.00
IUUC-Mga-060078	Meleagris gallopavo	46.89	0.00e+00	671.00
IUUC-Mvi-060519	Microbotryum violaceum	50.52	0.00e+00	758.00
IUUC-Mmr-061312	Microcebus murinus	46.89	0.00e+00	672.00
IUUC-Mdo-062867	Monodelphis domestica	46.64	0.00e+00	667.00
IUUC-Mmu-063336	Mus musculus	46.89	0.00e+00	671.00
IUUC-Mac-065440	Musa acuminata	31.63	4.00e-95	340.00
IUUC-Mpu-066400	Mustela putorius furo	46.07	8.00e-160	555.00
IUUC-Mlu-067800	Myotis lucifugus	46.64	0.00e+00	671.00
IUUC-Nfi-068384	Neosartorya fischeri	83.38	0.00e+00	1251.00
IUUC-Ncr-068965	Neurospora crassa	63.78	0.00e+00	981.00
IUUC-Nle-069729	Nomascus leucogenys	46.89	0.00e+00	672.00
IUUC-Opr-071197	Ochotona princeps	33.24	2.00e-103	368.00
IUUC-Ont-071729	Oreochromis niloticus	46.39	0.00e+00	663.00
IUUC-Oan-073309	Ornithorhynchus anatinus	46.89	0.00e+00	671.00
IUUC-Ocu-074661	Oryctolagus cuniculus	47.03	0.00e+00	664.00
IUUC-Obr-076260	Oryza brachyantha	30.59	2.00e-95	341.00
IUUC-Ogl-077579	Oryza glaberrima	30.72	5.00e-96	343.00
IUUC-Ola-087422	Oryzias latipes	46.78	0.00e+00	668.00
IUUC-Olu-087721	Ostreococcus lucimarinus	29.78	4.00e-84	303.00
IUUC-Oga-088130	Otolemur garnettii	46.89	0.00e+00	672.00
IUUC-Oar-089510	Ovis aries	46.04	0.00e+00	632.00
IUUC-Ptr-090665	Pan troglodytes	46.89	0.00e+00	672.00
IUUC-Pan-092218	Papio anubis	46.89	0.00e+00	672.00
IUUC-Psi-093175	Pelodiscus sinensis	46.89	0.00e+00	671.00
IUUC-Pma-094502	Petromyzon marinus	46.55	0.00e+00	656.00
IUUC-Pno-095067	Phaeosphaeria nodorum	67.89	0.00e+00	1074.00
IUUC-Ppa-095864	Physcomitrella patens	30.82	2.00e-89	321.00
IUUC-Pfo-096705	Poecilia formosa	46.39	0.00e+00	683.00
IUUC-Pab-097578	Pongo abelii	46.89	0.00e+00	672.00
IUUC-Pca-100242	Procavia capensis	50.81	8.00e-142	495.00
IUUC-Ppe-101405	Prunus persica	31.11	1.00e-93	335.00
IUUC-Pva-102155	Pteropus vampyrus	41.19	1.00e-156	545.00
IUUC-Pgr-103297	Puccinia graminis	49.74	0.00e+00	747.00
IUUC-Ptt-103706	Puccinia triticina	48.00	6.00e-108	384.00
IUUC-Pte-104257	Pyrenophora teres	66.49	0.00e+00	1061.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	66.62	0.00e+00	1062.00
IUUC-Rno-105939	Rattus norvegicus	46.89	0.00e+00	671.00
IUUC-Sce-106293	Saccharomyces cerevisiae	32.93	2.00e-129	454.00
IUUC-Sha-106949	Sarcophilus harrisii	46.89	0.00e+00	671.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	46.48	0.00e+00	661.00
IUUC-Spo-108280	Schizosaccharomyces pombe	46.28	0.00e+00	661.00
IUUC-Stu-112374	Solanum tuberosum	30.39	3.00e-90	324.00
IUUC-Sar-113138	Sorex araneus	36.44	2.00e-126	444.00
IUUC-Sre-114984	Sporisorium reilianum	49.88	0.00e+00	709.00
IUUC-Ssc-115829	Sus scrofa	46.71	0.00e+00	658.00
IUUC-Tgu-116950	Taeniopygia guttata	46.89	0.00e+00	671.00
IUUC-Tru-118558	Takifugu rubripes	46.26	0.00e+00	675.00
IUUC-Tsy-119621	Tarsius syrichta	39.04	2.00e-102	365.00
IUUC-Tni-120460	Tetraodon nigroviridis	46.26	0.00e+00	679.00
IUUC-Tre-122223	Trichoderma reesei	63.47	0.00e+00	949.00
IUUC-Tvi-122539	Trichoderma virens	62.57	0.00e+00	924.00
IUUC-Tae-124198	Triticum aestivum	30.98	5.00e-98	350.00
IUUC-Tme-126926	Tuber melanosporum	66.41	0.00e+00	1040.00
IUUC-Tbe-127369	Tupaia belangeri	52.44	6.00e-91	327.00
IUUC-Ttr-129022	Tursiops truncatus	47.12	1.00e-149	521.00
IUUC-Uma-129341	Ustilago maydis	49.31	0.00e+00	679.00
IUUC-Vda-129857	Verticillium dahliae	63.85	0.00e+00	969.00
IUUC-Vpa-130166	Vicugna pacos	42.24	2.00e-139	487.00
IUUC-Vvi-131423	Vitis vinifera	30.46	4.00e-94	337.00
IUUC-Xtr-131818	Xenopus tropicalis	46.89	0.00e+00	663.00
IUUC-Xma-134206	Xiphophorus maculatus	46.39	0.00e+00	663.00
IUUC-Yli-134486	Yarrowia lipolytica	41.40	4.00e-169	586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence