iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055297

UUCD1 version

UUC-MaM-00734

Ensembl Protein ID

ENSMMUP00000033564.2

UniProt Accession

F7GTS0; I2CTB6; F7GTS0_MACMU

Genbank Protein ID

AFJ70201.1

Protein Name

E3 ubiquitin-protein ligase Arkadia

Genbank Nucleotide ID

JSUE03038414

Gene Name

RNF111

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000013089.3	ENSMMUT00000040506.2	ENSMMUP00000033564.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.60e-07	30.7	932	973

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCl+ +++g  ++ lpC H+fh+ C+ +w        ++ +CP+Cr
   Q: 932  CTICLSILEEGedVRRLPCMHLFHQVCVDQW------LITNKKCPICR 973
           9*****9944444******************......**********8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSQWTPEYNE LYTLKVDMKS EIPSDAPKTQ ESLKGILLHP EPIGAAKSFP AGVEMINSKV 60
GNEFSHLCDD SQKQEKDMNG NQQEQEKSVV RKKRKSQQAG PSYVQNCVKE NQGILGLRQH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGGCTACT GCGCTCTCAC TTTCCGAACT GTCGTAAAGG CCCCTAGTGT CGTGCTCTCC 60
TCGGTAGGGG AGGAATTGGT TAGGCGGCGG CGGCGGCGGC GGCGGTAGGG GAGCAGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR029306--RNF111_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF15303--RNF111_N
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007389--P:pattern specification process
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001378	Ailuropoda melanoleuca	93.32	0.00e+00	1431.00
IUUC-Atr-002613	Amborella trichopoda	34.02	5.00e-15	76.30
IUUC-Apl-003634	Anas platyrhynchos	83.84	0.00e+00	1261.00
IUUC-Aca-004574	Anolis carolinensis	77.16	5.00e-129	454.00
IUUC-Acl-008067	Aspergillus clavatus	44.64	2.00e-10	61.20
IUUC-Ang-009544	Aspergillus niger	53.33	3.00e-10	60.80
IUUC-Ate-010250	Aspergillus terreus	51.11	6.00e-10	59.70
IUUC-Bta-012823	Bos taurus	93.97	0.00e+00	1453.00
IUUC-Cja-018850	Callithrix jacchus	92.97	0.00e+00	1322.00
IUUC-Cfa-021062	Canis familiaris	95.94	0.00e+00	1467.00
IUUC-Cpo-021467	Cavia porcellus	87.92	0.00e+00	1338.00
IUUC-Csa-024048	Chlorocebus sabaeus	98.98	0.00e+00	1509.00
IUUC-Cho-024278	Choloepus hoffmanni	88.66	5.00e-145	508.00
IUUC-Dre-028323	Danio rerio	50.93	1.00e-158	553.00
IUUC-Dno-028850	Dasypus novemcinctus	89.77	0.00e+00	1335.00
IUUC-Dme-031973	Drosophila melanogaster	39.51	8.00e-26	113.00
IUUC-Ete-032985	Echinops telfairi	91.25	2.00e-118	420.00
IUUC-Eca-033659	Equus caballus	94.06	0.00e+00	1482.00
IUUC-Eeu-034773	Erinaceus europaeus	84.09	0.00e+00	754.00
IUUC-Fca-035560	Felis catus	95.44	0.00e+00	1421.00
IUUC-Fal-037598	Ficedula albicollis	82.89	0.00e+00	1283.00
IUUC-Gmo-038696	Gadus morhua	70.00	2.00e-64	240.00
IUUC-Gga-040900	Gallus gallus	84.72	0.00e+00	1285.00
IUUC-Gac-041830	Gasterosteus aculeatus	53.21	6.00e-172	598.00
IUUC-Gma-043396	Glycine max	45.57	6.00e-14	70.50
IUUC-Ggo-044921	Gorilla gorilla	96.61	0.00e+00	1534.00
IUUC-Hsa-046529	Homo sapiens	97.48	0.00e+00	1533.00
IUUC-Itr-048765	Ictidomys tridecemlineatus	95.47	0.00e+00	1414.00
IUUC-Lch-049512	Latimeria chalumnae	72.72	0.00e+00	1023.00
IUUC-Lpe-051474	Leersia perrieri	35.42	7.00e-13	69.30
IUUC-Loc-052174	Lepisosteus oculatus	57.06	0.00e+00	702.00
IUUC-Laf-053804	Loxodonta africana	91.85	0.00e+00	1303.00
IUUC-Meu-056052	Macropus eugenii	80.23	2.00e-113	403.00
IUUC-Mtr-058136	Medicago truncatula	55.32	4.00e-13	67.40
IUUC-Mga-059350	Meleagris gallopavo	83.94	0.00e+00	1273.00
IUUC-Mmr-061666	Microcebus murinus	96.55	0.00e+00	1498.00
IUUC-Mdo-061958	Monodelphis domestica	88.55	0.00e+00	1342.00
IUUC-Mmu-063900	Mus musculus	87.71	0.00e+00	1312.00
IUUC-Mac-065281	Musa acuminata	33.91	1.00e-11	62.00
IUUC-Mpu-066492	Mustela putorius furo	95.84	0.00e+00	1474.00
IUUC-Mlu-067464	Myotis lucifugus	93.88	0.00e+00	1396.00
IUUC-Nfi-068528	Neosartorya fischeri	51.11	7.00e-10	59.70
IUUC-Nle-070038	Nomascus leucogenys	96.31	0.00e+00	1533.00
IUUC-Opr-070924	Ochotona princeps	81.33	0.00e+00	763.00
IUUC-Ont-072297	Oreochromis niloticus	52.64	4.00e-100	359.00
IUUC-Oan-072897	Ornithorhynchus anatinus	64.87	0.00e+00	865.00
IUUC-Ocu-074713	Oryctolagus cuniculus	93.21	0.00e+00	1438.00
IUUC-Oba-075898	Oryza barthii	37.50	3.00e-13	70.50
IUUC-Obr-076337	Oryza brachyantha	33.66	5.00e-13	69.70
IUUC-Ogl-077587	Oryza glaberrima	37.50	3.00e-13	70.50
IUUC-Ogu-078729	Oryza glumaepatula	37.50	3.00e-13	70.50
IUUC-Oin-079127	Oryza indica	37.50	3.00e-13	70.50
IUUC-Olo-080490	Oryza longistaminata	37.50	3.00e-13	70.50
IUUC-Ome-081451	Oryza meridionalis	37.50	3.00e-13	70.50
IUUC-Oni-082106	Oryza nivara	37.50	3.00e-13	70.50
IUUC-Opu-084108	Oryza punctata	37.50	2.00e-13	70.90
IUUC-Oru-085229	Oryza rufipogon	37.50	3.00e-13	70.50
IUUC-Osa-085404	Oryza sativa	37.50	3.00e-13	70.50
IUUC-Ola-087455	Oryzias latipes	52.33	9.00e-175	607.00
IUUC-Oga-088809	Otolemur garnettii	95.39	0.00e+00	1506.00
IUUC-Oar-090286	Ovis aries	94.53	0.00e+00	1492.00
IUUC-Ptr-091451	Pan troglodytes	96.61	0.00e+00	1528.00
IUUC-Pan-092593	Papio anubis	98.29	0.00e+00	1504.00
IUUC-Psi-093662	Pelodiscus sinensis	84.55	0.00e+00	1250.00
IUUC-Pma-094624	Petromyzon marinus	57.53	8.00e-64	238.00
IUUC-Ppa-095313	Physcomitrella patens	34.02	6.00e-15	76.60
IUUC-Pfo-096611	Poecilia formosa	51.48	2.00e-178	620.00
IUUC-Pab-097885	Pongo abelii	97.97	0.00e+00	1526.00
IUUC-Pca-100561	Procavia capensis	79.37	0.00e+00	733.00
IUUC-Pva-102891	Pteropus vampyrus	95.08	0.00e+00	1528.00
IUUC-Rno-105327	Rattus norvegicus	88.82	0.00e+00	1349.00
IUUC-Sha-107401	Sarcophilus harrisii	88.95	0.00e+00	1350.00
IUUC-Sit-110290	Setaria italica	40.62	2.00e-14	74.70
IUUC-Sar-113238	Sorex araneus	87.04	0.00e+00	880.00
IUUC-Sbi-114185	Sorghum bicolor	50.94	3.00e-14	71.20
IUUC-Ssc-116436	Sus scrofa	94.07	0.00e+00	1481.00
IUUC-Tgu-116470	Taeniopygia guttata	81.98	0.00e+00	1184.00
IUUC-Tru-118054	Takifugu rubripes	49.47	5.00e-161	561.00
IUUC-Tni-120063	Tetraodon nigroviridis	52.36	0.00e+00	628.00
IUUC-Tur-126415	Triticum urartu	53.70	4.00e-14	70.90
IUUC-Tbe-128026	Tupaia belangeri	89.52	0.00e+00	1249.00
IUUC-Ttr-128623	Tursiops truncatus	90.45	0.00e+00	1362.00
IUUC-Vpa-130662	Vicugna pacos	90.94	0.00e+00	1449.00
IUUC-Vvi-131609	Vitis vinifera	36.46	1.00e-12	68.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence