iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036346

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02095714

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015113.2	ENSFCAT00000015117.2	ENSFCAP00000014018.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.60e-24	82.7	307	336
E3 adaptor/Cullin RING/APC_C/CDC20	9.90e-128	425.7	172	442

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa++gd+ +l ++ +++d+++sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMeQPGDYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarvg+L Wn+++lssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTSHSARVGSLCWNSYILSSGSRSGHIHHHDVRVAEHHVATLTGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAQSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgh 266
           lkg 
   Q: 439  LKGR 442
           *985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MAQFVFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPAP SPMRAANRSH SAGRTPSRTP 60
GKSSSKAQTT PSKPGGDRYI PHRSASQMEV ASFLLSKENQ PENSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCCGCGG GCATCCACTC CAAGGACCCC TCCTCCTGCA GACGCTCCCA TGGCGCAGTT 60
CGTGTTCGAG AGTGACCTGC ACTCGTTGCT GCAGCTGGAT GCACCCATCC CCAATGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	44.84	3.00e-97	348.00
IUUC-Aml-001545	Ailuropoda melanoleuca	98.19	0.00e+00	870.00
IUUC-Atr-003103	Amborella trichopoda	44.62	1.00e-94	340.00
IUUC-Apl-003255	Anas platyrhynchos	80.63	0.00e+00	662.00
IUUC-Aca-004920	Anolis carolinensis	76.50	0.00e+00	687.00
IUUC-Aly-006012	Arabidopsis lyrata	46.81	1.00e-94	340.00
IUUC-Ate-010479	Aspergillus terreus	51.06	5.00e-80	291.00
IUUC-Ame-010850	Astyanax mexicanus	60.70	2.00e-90	325.00
IUUC-Bgr-012059	Blumeria graminis	49.64	9.00e-84	304.00
IUUC-Bta-012625	Bos taurus	97.73	0.00e+00	867.00
IUUC-Bci-013607	Botrytis cinerea	50.53	7.00e-87	314.00
IUUC-Bdi-014344	Brachypodium distachyon	45.62	7.00e-96	344.00
IUUC-Bol-015368	Brassica oleracea	44.44	4.00e-92	333.00
IUUC-Bra-016738	Brassica rapa	44.21	9.00e-92	331.00
IUUC-Cja-019132	Callithrix jacchus	97.05	0.00e+00	861.00
IUUC-Cfa-020780	Canis familiaris	97.96	0.00e+00	867.00
IUUC-Cpo-022223	Cavia porcellus	96.83	0.00e+00	813.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.00	7.00e-105	374.00
IUUC-Csa-023666	Chlorocebus sabaeus	97.73	0.00e+00	865.00
IUUC-Cho-024920	Choloepus hoffmanni	97.52	6.00e-162	563.00
IUUC-Cin-025675	Ciona intestinalis	49.46	1.00e-118	419.00
IUUC-Csv-026019	Ciona savignyi	50.53	1.00e-112	399.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.14	2.00e-85	310.00
IUUC-Cme-027234	Cyanidioschyzon merolae	50.00	5.00e-92	331.00
IUUC-Dre-028026	Danio rerio	61.49	4.00e-164	571.00
IUUC-Dno-028865	Dasypus novemcinctus	96.15	0.00e+00	849.00
IUUC-Dor-030958	Dipodomys ordii	96.15	0.00e+00	834.00
IUUC-Dse-031391	Dothistroma septosporum	38.63	1.00e-84	307.00
IUUC-Dme-031905	Drosophila melanogaster	48.32	2.00e-124	439.00
IUUC-Ete-032387	Echinops telfairi	91.61	0.00e+00	820.00
IUUC-Eca-033522	Equus caballus	86.17	0.00e+00	768.00
IUUC-Eeu-035059	Erinaceus europaeus	85.03	0.00e+00	712.00
IUUC-Fal-037558	Ficedula albicollis	80.72	0.00e+00	721.00
IUUC-Fox-037850	Fusarium oxysporum	44.54	2.00e-86	313.00
IUUC-Fso-038375	Fusarium solani	44.44	7.00e-87	314.00
IUUC-Gmo-039284	Gadus morhua	63.90	1.00e-162	566.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.04	2.00e-86	313.00
IUUC-Gga-040790	Gallus gallus	80.27	0.00e+00	738.00
IUUC-Gac-041431	Gasterosteus aculeatus	63.37	2.00e-161	562.00
IUUC-Gma-044259	Glycine max	43.62	2.00e-83	302.00
IUUC-Ggo-045052	Gorilla gorilla	98.19	0.00e+00	867.00
IUUC-Hsa-046305	Homo sapiens	98.19	0.00e+00	867.00
IUUC-Hvu-047476	Hordeum vulgare	43.47	3.00e-96	345.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	97.05	0.00e+00	816.00
IUUC-Lch-050174	Latimeria chalumnae	60.87	6.00e-149	520.00
IUUC-Lpe-050954	Leersia perrieri	45.94	2.00e-87	316.00
IUUC-Loc-052638	Lepisosteus oculatus	64.14	3.00e-159	555.00
IUUC-Lma-052998	Leptosphaeria maculans	43.07	1.00e-89	323.00
IUUC-Laf-053742	Loxodonta africana	97.73	0.00e+00	865.00
IUUC-Mcc-054948	Macaca mulatta	97.73	0.00e+00	865.00
IUUC-Meu-056013	Macropus eugenii	86.93	1.00e-142	499.00
IUUC-Mor-057277	Magnaporthe oryzae	45.09	2.00e-84	306.00
IUUC-Mpo-057624	Magnaporthe poae	51.10	5.00e-85	308.00
IUUC-Mtr-057725	Medicago truncatula	44.53	5.00e-86	311.00
IUUC-Mga-060102	Meleagris gallopavo	80.54	0.00e+00	739.00
IUUC-Mmr-061615	Microcebus murinus	97.96	0.00e+00	868.00
IUUC-Mdo-061982	Monodelphis domestica	89.57	0.00e+00	778.00
IUUC-Mmu-063864	Mus musculus	94.78	0.00e+00	822.00
IUUC-Mac-064861	Musa acuminata	44.55	9.00e-97	347.00
IUUC-Mpu-066502	Mustela putorius furo	98.19	0.00e+00	861.00
IUUC-Mlu-067277	Myotis lucifugus	89.16	0.00e+00	776.00
IUUC-Ncr-068951	Neurospora crassa	45.00	2.00e-83	303.00
IUUC-Nle-070149	Nomascus leucogenys	97.96	0.00e+00	867.00
IUUC-Opr-070778	Ochotona princeps	95.82	0.00e+00	687.00
IUUC-Ont-071660	Oreochromis niloticus	62.16	6.00e-157	547.00
IUUC-Oan-073677	Ornithorhynchus anatinus	75.23	3.00e-177	614.00
IUUC-Ocu-073797	Oryctolagus cuniculus	97.27	0.00e+00	859.00
IUUC-Oba-075946	Oryza barthii	46.02	9.00e-95	340.00
IUUC-Obr-076018	Oryza brachyantha	44.88	3.00e-95	342.00
IUUC-Ogl-077254	Oryza glaberrima	46.13	2.00e-87	316.00
IUUC-Ogu-078562	Oryza glumaepatula	46.13	1.00e-87	316.00
IUUC-Oin-080094	Oryza indica	46.13	2.00e-87	316.00
IUUC-Olo-080449	Oryza longistaminata	46.13	1.00e-87	317.00
IUUC-Ome-081186	Oryza meridionalis	45.76	1.00e-94	341.00
IUUC-Oni-082243	Oryza nivara	46.13	2.00e-87	316.00
IUUC-Opu-084007	Oryza punctata	46.13	5.00e-87	314.00
IUUC-Oru-084562	Oryza rufipogon	46.13	2.00e-94	340.00
IUUC-Osa-085566	Oryza sativa	45.82	9.00e-95	340.00
IUUC-Ola-086907	Oryzias latipes	62.22	6.00e-149	520.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.20	2.00e-103	369.00
IUUC-Oga-088184	Otolemur garnettii	97.92	0.00e+00	852.00
IUUC-Oar-090023	Ovis aries	91.93	0.00e+00	767.00
IUUC-Ptr-090935	Pan troglodytes	97.11	0.00e+00	801.00
IUUC-Pan-091845	Papio anubis	97.73	0.00e+00	865.00
IUUC-Psi-093188	Pelodiscus sinensis	81.58	0.00e+00	766.00
IUUC-Pma-094187	Petromyzon marinus	55.01	8.00e-132	463.00
IUUC-Pno-094809	Phaeosphaeria nodorum	42.37	2.00e-89	323.00
IUUC-Ppa-095457	Physcomitrella patens	46.45	1.00e-96	346.00
IUUC-Pfo-097429	Poecilia formosa	59.23	4.00e-139	487.00
IUUC-Pab-098603	Pongo abelii	97.96	0.00e+00	867.00
IUUC-Pop-099654	Populus trichocarpa	44.53	4.00e-89	321.00
IUUC-Pca-101062	Procavia capensis	96.60	0.00e+00	842.00
IUUC-Ppe-101865	Prunus persica	44.75	8.00e-83	300.00
IUUC-Pva-102925	Pteropus vampyrus	95.92	0.00e+00	855.00
IUUC-Pte-104142	Pyrenophora teres	42.41	2.00e-87	316.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	42.23	2.00e-87	316.00
IUUC-Rno-106005	Rattus norvegicus	94.78	0.00e+00	820.00
IUUC-Sha-107472	Sarcophilus harrisii	89.59	0.00e+00	786.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	43.44	2.00e-83	303.00
IUUC-Spo-108075	Schizosaccharomyces pombe	45.92	2.00e-85	309.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	49.02	2.00e-86	312.00
IUUC-Smo-108922	Selaginella moellendorffii	48.28	1.00e-107	382.00
IUUC-Sit-110732	Setaria italica	45.26	6.00e-96	344.00
IUUC-Stu-112676	Solanum tuberosum	43.23	6.00e-83	301.00
IUUC-Sar-113092	Sorex araneus	91.38	0.00e+00	778.00
IUUC-Sbi-114558	Sorghum bicolor	44.15	6.00e-96	344.00
IUUC-Ssc-115710	Sus scrofa	98.41	0.00e+00	872.00
IUUC-Tgu-117100	Taeniopygia guttata	79.60	0.00e+00	718.00
IUUC-Tru-118184	Takifugu rubripes	61.19	8.00e-125	440.00
IUUC-Tsy-118892	Tarsius syrichta	97.16	2.00e-162	564.00
IUUC-Tni-120474	Tetraodon nigroviridis	60.67	8.00e-153	533.00
IUUC-Tca-120949	Theobroma cacao	44.50	1.00e-92	333.00
IUUC-Tre-122211	Trichoderma reesei	39.81	7.00e-86	310.00
IUUC-Tvi-122531	Trichoderma virens	40.19	6.00e-86	311.00
IUUC-Tae-123765	Triticum aestivum	45.30	9.00e-97	347.00
IUUC-Tur-126193	Triticum urartu	44.52	3.00e-96	345.00
IUUC-Tme-126905	Tuber melanosporum	48.54	9.00e-83	301.00
IUUC-Tbe-127384	Tupaia belangeri	98.32	5.00e-176	610.00
IUUC-Ttr-128511	Tursiops truncatus	97.96	0.00e+00	865.00
IUUC-Vda-129993	Verticillium dahliae	39.95	1.00e-86	313.00
IUUC-Xtr-131993	Xenopus tropicalis	74.95	0.00e+00	682.00
IUUC-Xma-133332	Xiphophorus maculatus	63.03	1.00e-155	543.00
IUUC-Yli-134501	Yarrowia lipolytica	50.99	3.00e-90	325.00
IUUC-Zma-135135	Zea mays	45.24	8.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence