iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000015849.3	ENSMMUT00000022270.3	ENSMMUP00000020835.2
ENSMMUG00000015849.3	ENSMMUT00000064316.1	ENSMMUP00000054405.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-07	31.9	227	277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 227  CAVCGQKIiveldeegliEN-TYQLSCNHVFHEFCIRGW----CIVGKKQTCPYCK 277
           9***9988888887777555.999***************....889999******7 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAGAAARKA ESVLEAPPQQ EQISHTKLSA EDAWNLQQER MYKMHRGHES MHVEMILIFL 60
CILVIAQIVL VQWRQRHGRS YNLVTLLQMW IVPLYFTIKL YWWRFLSMWG MFSVITSYIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCCCGCG GCCCCGCGGC GCTACTTTGC GGACTCTGCG GGACCCTCCC CCGCAGGCGC 60
TGTGCGCTGG AGAAGGCACA GGCGCGCAGG CATGGCCGCG GGGGCGGCCG CGCGGAAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

mcc:697243

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001696	Ailuropoda melanoleuca	94.32	1.00e-180	625.00
IUUC-Ani-009461	Aspergillus nidulans	29.21	5.00e-04	39.70
IUUC-Bta-012417	Bos taurus	94.29	0.00e+00	627.00
IUUC-Cja-018928	Callithrix jacchus	95.91	0.00e+00	631.00
IUUC-Csa-024195	Chlorocebus sabaeus	99.22	2.00e-152	531.00
IUUC-Dre-028154	Danio rerio	77.02	1.00e-151	528.00
IUUC-Dno-030042	Dasypus novemcinctus	94.97	2.00e-174	605.00
IUUC-Ete-032805	Echinops telfairi	79.05	7.00e-138	483.00
IUUC-Eeu-035318	Erinaceus europaeus	83.91	2.00e-150	525.00
IUUC-Fca-036592	Felis catus	97.07	0.00e+00	627.00
IUUC-Gac-042092	Gasterosteus aculeatus	75.42	4.00e-146	510.00
IUUC-Ggo-044923	Gorilla gorilla	97.48	0.00e+00	644.00
IUUC-Hsa-046067	Homo sapiens	97.78	0.00e+00	628.00
IUUC-Itr-049039	Ictidomys tridecemlineatus	95.77	1.00e-179	622.00
IUUC-Loc-052668	Lepisosteus oculatus	76.34	2.00e-152	531.00
IUUC-Mmr-060873	Microcebus murinus	92.36	1.00e-166	578.00
IUUC-Mpu-066792	Mustela putorius furo	95.90	0.00e+00	633.00
IUUC-Mlu-066938	Myotis lucifugus	90.06	6.00e-177	613.00
IUUC-Nle-069138	Nomascus leucogenys	98.42	0.00e+00	653.00
IUUC-Opr-070342	Ochotona princeps	91.53	1.00e-171	595.00
IUUC-Ont-072601	Oreochromis niloticus	77.48	8.00e-150	522.00
IUUC-Ocu-074696	Oryctolagus cuniculus	93.99	0.00e+00	629.00
IUUC-Ola-086347	Oryzias latipes	77.15	3.00e-149	520.00
IUUC-Oga-089139	Otolemur garnettii	96.42	2.00e-179	620.00
IUUC-Ptr-091158	Pan troglodytes	98.42	0.00e+00	653.00
IUUC-Pfo-096037	Poecilia formosa	77.35	6.00e-144	503.00
IUUC-Pab-097624	Pongo abelii	97.48	0.00e+00	643.00
IUUC-Sar-113082	Sorex araneus	90.91	3.00e-136	477.00
IUUC-Tru-118649	Takifugu rubripes	72.10	1.00e-134	472.00
IUUC-Tsy-118809	Tarsius syrichta	92.86	3.00e-163	567.00
IUUC-Tbe-127912	Tupaia belangeri	74.51	7.00e-132	463.00
IUUC-Vpa-130356	Vicugna pacos	92.86	9.00e-168	582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence