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Tag Content
UUCD2 ID IUUC-Mlu-067732
UUCD1 version UUC-MyL-01158
Ensembl Protein ID ENSMLUP00000010803.2
UniProt Accession G1PJ85; G1PJ85_MYOLU
Genbank Protein ID ENSMLUP00000010803
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAPE02012181
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000011846.2 ENSMLUT00000011858.2 ENSMLUP00000010803.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.00e-114 382.4 185 719
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +    ++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+
   Q: 185  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGGLVRTDKKPAICKSYLKLMTELWhKSRPGSVVPTNLFQGIKTVNPTFRGYS 268
           7******************************.....999999*******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde........................................ 129
           qqDaqEfl++l+d l+eelk+         ++  +ee++eedks+++ +                                        
   Q: 269  QQDAQEFLRCLMDLLHEELKEqvmeveedAQTIMTEETMEEDKSQSDVDfqscescsgsdkaendsgsrgfsednnettmliqddenns 357
           *******************8888887765555555666666656555559*************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 358  emskdwqkekmcnkinkvnsegeldkdkdsvsetddlnnqetvkvqihgraseyitdvhlndlstpqilpsnegvnprlsasppksksg 446
           ***************************************************************************************** PP
   S: 130  .....................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............ 185
                                +++k++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+            
   Q: 447  nlwpglastqkrvlaqsasspKRKKQHKKYRSVISDVFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhssshptsivka 535
           *********************9**************************************************99888************ PP
   S: 186  .....................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRf 237
                                                +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L++hLkRf
   Q: 536  gscgeayapqgwiaffmeyvkrfvvscvptwfwgpivTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF 624
           ***************************************************************************************** PP
   S: 238  sfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevle 324
             ++e ++++ki+++v+fple Ldl+pf+++++ +q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v++
   Q: 625  --RHELMFSTKISTHVSFPLEgLDLQPFLAKDSPAQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEVSESTVQN 709
           ..9999*************************88777..9**************************88889******************* PP
   S: 325  etgstaYvlfYkr 337
              ++aYvlfY++
   Q: 710  ---AEAYVLFYRK 719
           ...********98 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
HTHIHSHKTF SVFKVLPHLE SPGKQEKIYN KMPGFRNHCS HLDSVGEITK EELIQKSHST 60
CQDCKVRGPN LWACLENRCS YVGCGESQVD HSTIHSQETK HYLTVNLTTL RVWCYACSKE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067732|DUB,USP|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CATACCCACA TACACTCACA CATGACATAT ACTACCTCAT TAAATCCTTA CAGTAACCCC 60
ATAAGTTAGG TATGCCATTC TGCTCTTACT GTTATTCCAG GTTTGACTTC AGAGTCCTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067732|DUB,USP|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001742 Ailuropoda melanoleuca 95.51 0.00e+00 1814.00
IUUC-Apl-003987 Anas platyrhynchos 81.17 0.00e+00 1481.00
IUUC-Aca-004713 Anolis carolinensis 76.03 0.00e+00 1418.00
IUUC-Bta-013132 Bos taurus 95.20 0.00e+00 1770.00
IUUC-Cel-018627 Caenorhabditis elegans 32.40 5.00e-37 149.00
IUUC-Cja-018811 Callithrix jacchus 94.66 0.00e+00 1793.00
IUUC-Cfa-021158 Canis familiaris 95.20 0.00e+00 1810.00
IUUC-Cpo-021910 Cavia porcellus 87.25 0.00e+00 1558.00
IUUC-Csa-023130 Chlorocebus sabaeus 95.09 0.00e+00 1764.00
IUUC-Cho-024383 Choloepus hoffmanni 76.70 0.00e+00 667.00
IUUC-Dre-028639 Danio rerio 70.16 0.00e+00 1248.00
IUUC-Dno-029416 Dasypus novemcinctus 92.69 0.00e+00 1694.00
IUUC-Ete-032994 Echinops telfairi 76.41 0.00e+00 858.00
IUUC-Eca-034248 Equus caballus 95.28 0.00e+00 1802.00
IUUC-Eeu-035357 Erinaceus europaeus 75.46 0.00e+00 1318.00
IUUC-Fca-036013 Felis catus 92.24 0.00e+00 1712.00
IUUC-Fal-037509 Ficedula albicollis 81.16 0.00e+00 1486.00
IUUC-Gmo-038944 Gadus morhua 65.13 0.00e+00 1191.00
IUUC-Gga-040647 Gallus gallus 80.83 0.00e+00 1464.00
IUUC-Gac-041752 Gasterosteus aculeatus 68.60 0.00e+00 1257.00
IUUC-Hsa-045694 Homo sapiens 93.55 0.00e+00 1782.00
IUUC-Itr-049041 Ictidomys tridecemlineatus 95.09 0.00e+00 1734.00
IUUC-Lch-050400 Latimeria chalumnae 69.91 0.00e+00 1268.00
IUUC-Loc-052616 Lepisosteus oculatus 71.85 0.00e+00 1324.00
IUUC-Laf-053493 Loxodonta africana 93.68 0.00e+00 1747.00
IUUC-Mcc-055542 Macaca mulatta 94.87 0.00e+00 1795.00
IUUC-Meu-056645 Macropus eugenii 72.91 0.00e+00 1292.00
IUUC-Mga-060019 Meleagris gallopavo 81.79 0.00e+00 1264.00
IUUC-Mmr-061241 Microcebus murinus 91.21 0.00e+00 1733.00
IUUC-Mmu-063786 Mus musculus 91.27 0.00e+00 1671.00
IUUC-Mpu-065772 Mustela putorius furo 95.21 0.00e+00 1474.00
IUUC-Nle-069528 Nomascus leucogenys 94.00 0.00e+00 1761.00
IUUC-Opr-070606 Ochotona princeps 88.32 0.00e+00 1575.00
IUUC-Ont-071495 Oreochromis niloticus 70.30 0.00e+00 1267.00
IUUC-Oan-073695 Ornithorhynchus anatinus 83.90 0.00e+00 1046.00
IUUC-Ocu-074457 Oryctolagus cuniculus 91.32 0.00e+00 1712.00
IUUC-Ola-086739 Oryzias latipes 68.97 0.00e+00 1291.00
IUUC-Oga-088720 Otolemur garnettii 92.48 0.00e+00 1764.00
IUUC-Oar-089921 Ovis aries 94.78 0.00e+00 1801.00
IUUC-Ptr-090526 Pan troglodytes 94.23 0.00e+00 1781.00
IUUC-Pan-092396 Papio anubis 95.09 0.00e+00 1801.00
IUUC-Psi-092971 Pelodiscus sinensis 81.85 0.00e+00 1541.00
IUUC-Pfo-097415 Poecilia formosa 69.50 0.00e+00 1274.00
IUUC-Pab-098740 Pongo abelii 95.09 0.00e+00 1786.00
IUUC-Pca-100598 Procavia capensis 82.50 0.00e+00 892.00
IUUC-Pva-102820 Pteropus vampyrus 91.26 0.00e+00 1517.00
IUUC-Rno-104894 Rattus norvegicus 91.06 0.00e+00 1680.00
IUUC-Sha-107244 Sarcophilus harrisii 76.81 0.00e+00 1399.00
IUUC-Sar-113665 Sorex araneus 91.75 0.00e+00 1763.00
IUUC-Ssc-115793 Sus scrofa 92.48 0.00e+00 1696.00
IUUC-Tgu-117487 Taeniopygia guttata 82.58 0.00e+00 1454.00
IUUC-Tru-117694 Takifugu rubripes 69.11 0.00e+00 1279.00
IUUC-Tsy-119598 Tarsius syrichta 81.50 0.00e+00 1454.00
IUUC-Tni-120189 Tetraodon nigroviridis 66.95 0.00e+00 1205.00
IUUC-Tbe-128125 Tupaia belangeri 82.42 2.00e-115 410.00
IUUC-Ttr-128269 Tursiops truncatus 90.89 0.00e+00 1650.00
IUUC-Vpa-130598 Vicugna pacos 92.61 0.00e+00 1743.00
IUUC-Xtr-132044 Xenopus tropicalis 74.67 0.00e+00 1318.00
Created Date 25-Jun-2017

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