iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062247

UUCD1 version

UUC-MoD-00398

Ensembl Protein ID

ENSMODP00000008927.4

UniProt Accession

F6X8W9; F6X8W9_MONDO

Protein Name

Uncharacterized protein

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007200.4	ENSMODT00000009102.4	ENSMODP00000008927.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-52	172.9	2062	2094
UBD/Beta-Prp	7.80e-83	278.2	1931	2184

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHt++vtc++f +d ++l++Gs+D ++ +WD+r
   Q: 2062 GHTGPVTCCSFsPDgGILATGSRDQSLLCWDVR 2094
           8***********999****************97 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghed 95
           s+  +v++spd+ ++a+g  ++ i+++++++g+   +    +a+v+a+ + + + +lv+g+eD++++ w   + t+  +  l +h++
   Q: 1931 SPALSVAISPDRAFVAVGHHSDGIRIYRTSSGTEEGQCPVSDAAVSALAWLNPK-VLVSGGEDGNLQCWmlAYVTPHRLWLLPAHQK 2016
           55667999********************************************96.**************66666999999999**** PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkl 171
            vl l+ s+  + l+s+s+d t+r+w l+  +  +          l+gh+g v+c +++pdg +l++Gs D+ +  Wd+   +   +
   Q: 2017 AVLGLATSQ--ELLASASEDFTVRLWSLQFLTQPNLakklhpgrELRGHTGPVTCCSFSPDGGILATGSRDQSLLCWDVrmpEAPVV 2101
           *********..***************8875554443669****************************************77777889 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
           ++ l   h d v+  s++++   l+s+s+dg+v+lwd  +g+ + ++ gh++ v+ v +   +e++vs+  Dg++++W+lr  +l+
   Q: 2102 MHSLPACHRDWVTGCSWTKD-AMLLSCSNDGSVRLWDPVSGQQLGQFLGHQSAVSTVVAV--EEHVVSVDRDGVLKVWNLRGVELT 2184
           ****999************8.7**************************************..*****************9976665 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MKSKGLEPSG QPGVLSLKNP ILTQSTDLQS TVSASHLLQP FQPSPLIEAS LKGMDTSNHL 60
LLEPAARKAQ DFTLGHFTKW PKRTLKATKS LGSTCQSQTI KRQGLELFGK PAVLSLENRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNAGCCTGC GGGGCCTTTC CATCAGCCCT 60
CCTTGCCTAG AAATCTAAGC AAGTCCGCTC TTCTTCCCCA CCCCCTTCCC CTCCTGTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0071011--C:precatalytic spliceosome
GO:0005697--C:telomerase holoenzyme complex
GO:0005682--C:U5 snRNP
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0008380--P:RNA splicing
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	59.83	0.00e+00	2719.00
IUUC-Aca-005102	Anolis carolinensis	42.69	0.00e+00	1668.00
IUUC-Ame-011165	Astyanax mexicanus	33.14	0.00e+00	785.00
IUUC-Bta-012323	Bos taurus	62.88	0.00e+00	2769.00
IUUC-Cja-019005	Callithrix jacchus	60.17	0.00e+00	2930.00
IUUC-Cfa-020803	Canis familiaris	57.67	0.00e+00	2527.00
IUUC-Cpo-022312	Cavia porcellus	61.23	0.00e+00	2702.00
IUUC-Csa-023287	Chlorocebus sabaeus	61.51	0.00e+00	2858.00
IUUC-Dre-028825	Danio rerio	34.10	0.00e+00	1116.00
IUUC-Dno-029455	Dasypus novemcinctus	62.00	0.00e+00	2713.00
IUUC-Dor-030328	Dipodomys ordii	59.01	0.00e+00	1980.00
IUUC-Ete-032385	Echinops telfairi	58.74	0.00e+00	1449.00
IUUC-Eca-033726	Equus caballus	62.29	0.00e+00	2888.00
IUUC-Eeu-034665	Erinaceus europaeus	52.79	4.00e-167	583.00
IUUC-Fca-035365	Felis catus	59.73	0.00e+00	2808.00
IUUC-Gmo-039584	Gadus morhua	31.67	4.00e-122	433.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.84	0.00e+00	988.00
IUUC-Ggo-045432	Gorilla gorilla	60.35	0.00e+00	2776.00
IUUC-Hsa-046182	Homo sapiens	60.24	0.00e+00	2870.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	62.70	0.00e+00	2798.00
IUUC-Lch-050186	Latimeria chalumnae	37.50	2.00e-80	293.00
IUUC-Laf-054524	Loxodonta africana	61.18	0.00e+00	2843.00
IUUC-Mcc-055628	Macaca mulatta	60.81	0.00e+00	2869.00
IUUC-Meu-056338	Macropus eugenii	79.93	0.00e+00	1677.00
IUUC-Mmr-060854	Microcebus murinus	61.90	0.00e+00	2884.00
IUUC-Mmu-064406	Mus musculus	56.95	0.00e+00	2638.00
IUUC-Mpu-065806	Mustela putorius furo	59.46	0.00e+00	2756.00
IUUC-Mlu-068116	Myotis lucifugus	61.52	0.00e+00	2744.00
IUUC-Nle-069628	Nomascus leucogenys	63.63	0.00e+00	2637.00
IUUC-Opr-070242	Ochotona princeps	61.24	0.00e+00	2143.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.10	0.00e+00	1932.00
IUUC-Ocu-073933	Oryctolagus cuniculus	61.04	0.00e+00	2840.00
IUUC-Ola-086886	Oryzias latipes	34.38	0.00e+00	1043.00
IUUC-Oga-088609	Otolemur garnettii	62.03	0.00e+00	2806.00
IUUC-Oar-089957	Ovis aries	62.30	0.00e+00	2696.00
IUUC-Ptr-090577	Pan troglodytes	59.15	0.00e+00	2820.00
IUUC-Pan-092397	Papio anubis	60.45	0.00e+00	2853.00
IUUC-Pma-094373	Petromyzon marinus	33.91	3.00e-74	273.00
IUUC-Pfo-096497	Poecilia formosa	34.32	0.00e+00	1024.00
IUUC-Pab-098028	Pongo abelii	60.02	0.00e+00	2850.00
IUUC-Pca-101002	Procavia capensis	67.76	0.00e+00	1530.00
IUUC-Pva-102144	Pteropus vampyrus	61.61	0.00e+00	1156.00
IUUC-Rno-105828	Rattus norvegicus	57.60	0.00e+00	2687.00
IUUC-Sha-106469	Sarcophilus harrisii	80.21	0.00e+00	4004.00
IUUC-Sar-113035	Sorex araneus	59.32	0.00e+00	1622.00
IUUC-Ssc-116122	Sus scrofa	64.52	0.00e+00	2256.00
IUUC-Tru-118412	Takifugu rubripes	32.43	0.00e+00	1097.00
IUUC-Tsy-119257	Tarsius syrichta	56.63	0.00e+00	1131.00
IUUC-Tni-120032	Tetraodon nigroviridis	30.25	2.00e-36	145.00
IUUC-Tbe-127312	Tupaia belangeri	60.67	7.00e-138	486.00
IUUC-Ttr-128335	Tursiops truncatus	58.99	0.00e+00	2712.00
IUUC-Xtr-132524	Xenopus tropicalis	39.34	0.00e+00	1365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence