iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068116

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02015121

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000015336.2	ENSMLUT00000015377.2	ENSMLUP00000014011.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-47	157.9	2043	2077
UBD/Beta-Prp	1.60e-77	260.7	1913	2160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gHt++v+c++f +d ++l++G++D ++ +WD+rt 
   Q: 2043 GHTGPVNCCSFsTDgCRLATGGRDRSLLCWDVRTP 2077
           8***********889*****************996 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvls 99
           +v+ spd++++a+g+r + i+++++++g+  ++ +  + +vta+ + + + +lv+g+eD+ ++ w l+  +++ +  +++ ++ vl 
   Q: 1913 SVALSPDGDQVAVGYRADGIRIYKISSGSQGAQCQALDVAVTALAWLSPE-VLVSGAEDGSLQGWALQesSFESLWLMSRYQKPVLG 1998
           46667777777777777777777777777777777777777777776665.777777777777775554467777777777777777 PP
   S: 100  lsfspsg.dklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrt 174
           l++s+++ +  +s  +d t+r+w  +  +  ++         l gh+g vnc +++ dg+ l++G+ Dr +  Wd+       l++ 
   Q: 1999 LASSQESsSLPLSIAEDFTVRLWPRQLLTLPQKaehfpcatELWGHTGPVNCCSFSTDGCRLATGGRDRSLLCWDVrtpTAPVLIHS 2085
           777774436667777777777776555555555666777767777777777777777777777777777777777733333447777 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
           +   h d v+  ++++ g+ l+s+s dg+v lwd + g+ +  + gh++ v+ v +   +e++vs++ Dg++++Wd +
   Q: 2086 FPACHRDWVTGCAWTK-GNLLISCSSDGSVGLWDPELGQQLGHFLGHQSAVSAVVAV--EEHVVSVGRDGTLKVWDHQ 2160
           7777777777777777.5777777777777777777777777777777777777777..7777777777777777744 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MEKLYGHVSA HPDILSLENR CLATLPDVKI MEKPHGHMSS HPDILSLENR CLATLPDMRL 60
MEKPHGHVSA HPDILSLENR CLATLSILKS PMSASSFLQC VQTSRLVQAD LCSLDTSNHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAAC TTTATGGGCA CGTGTCTGCC CACCCAGACA TCCTCTCCTT GGAGAACCGA 60
TGCCTGGCCA CACTTCCTGA TGTGAAGATC ATGGAGAAAC CACATGGACA TATGTCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	80.90	0.00e+00	3923.00
IUUC-Aca-005102	Anolis carolinensis	42.54	0.00e+00	1635.00
IUUC-Ame-011822	Astyanax mexicanus	34.61	0.00e+00	631.00
IUUC-Bta-012323	Bos taurus	80.76	0.00e+00	3989.00
IUUC-Cja-019005	Callithrix jacchus	80.41	0.00e+00	4063.00
IUUC-Cfa-020803	Canis familiaris	73.34	0.00e+00	3453.00
IUUC-Cpo-022312	Cavia porcellus	74.24	0.00e+00	3451.00
IUUC-Csa-023287	Chlorocebus sabaeus	81.53	0.00e+00	4053.00
IUUC-Dre-028825	Danio rerio	34.89	0.00e+00	1129.00
IUUC-Dno-029455	Dasypus novemcinctus	79.72	0.00e+00	3820.00
IUUC-Dor-030328	Dipodomys ordii	73.30	0.00e+00	2524.00
IUUC-Ete-032385	Echinops telfairi	75.34	0.00e+00	1968.00
IUUC-Eca-033726	Equus caballus	85.56	0.00e+00	4289.00
IUUC-Eeu-034665	Erinaceus europaeus	67.03	0.00e+00	999.00
IUUC-Fca-035365	Felis catus	82.42	0.00e+00	4020.00
IUUC-Gmo-039584	Gadus morhua	31.55	7.00e-111	396.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.93	0.00e+00	995.00
IUUC-Ggo-045432	Gorilla gorilla	79.08	0.00e+00	3854.00
IUUC-Hsa-046182	Homo sapiens	81.01	0.00e+00	4060.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	79.35	0.00e+00	3926.00
IUUC-Lch-050186	Latimeria chalumnae	37.99	5.00e-76	278.00
IUUC-Laf-054524	Loxodonta africana	79.95	0.00e+00	4006.00
IUUC-Mcc-055628	Macaca mulatta	81.67	0.00e+00	4070.00
IUUC-Meu-056338	Macropus eugenii	63.52	0.00e+00	1294.00
IUUC-Mmr-060854	Microcebus murinus	80.48	0.00e+00	4006.00
IUUC-Mdo-062247	Monodelphis domestica	61.64	0.00e+00	2789.00
IUUC-Mmu-064406	Mus musculus	73.26	0.00e+00	3540.00
IUUC-Mpu-065806	Mustela putorius furo	80.19	0.00e+00	3947.00
IUUC-Nle-069628	Nomascus leucogenys	81.05	0.00e+00	3601.00
IUUC-Opr-070242	Ochotona princeps	78.09	0.00e+00	2790.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.87	0.00e+00	1917.00
IUUC-Ocu-073933	Oryctolagus cuniculus	78.79	0.00e+00	3852.00
IUUC-Ola-086886	Oryzias latipes	34.98	0.00e+00	1026.00
IUUC-Oga-088609	Otolemur garnettii	78.44	0.00e+00	3843.00
IUUC-Oar-089957	Ovis aries	80.80	0.00e+00	3899.00
IUUC-Ptr-090577	Pan troglodytes	79.79	0.00e+00	3981.00
IUUC-Pan-092397	Papio anubis	81.14	0.00e+00	4051.00
IUUC-Pma-094373	Petromyzon marinus	33.59	6.00e-66	245.00
IUUC-Pfo-096497	Poecilia formosa	36.07	0.00e+00	1059.00
IUUC-Pab-098028	Pongo abelii	80.94	0.00e+00	4001.00
IUUC-Pca-101002	Procavia capensis	83.01	0.00e+00	1861.00
IUUC-Pva-102144	Pteropus vampyrus	79.62	0.00e+00	1825.00
IUUC-Rno-105828	Rattus norvegicus	72.74	0.00e+00	3581.00
IUUC-Sha-106469	Sarcophilus harrisii	61.58	0.00e+00	2861.00
IUUC-Sar-113035	Sorex araneus	77.06	0.00e+00	1428.00
IUUC-Ssc-116122	Sus scrofa	84.49	0.00e+00	3053.00
IUUC-Tru-118412	Takifugu rubripes	32.76	0.00e+00	1116.00
IUUC-Tsy-119257	Tarsius syrichta	74.59	0.00e+00	1528.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.77	1.00e-38	153.00
IUUC-Tbe-127312	Tupaia belangeri	67.69	0.00e+00	1019.00
IUUC-Ttr-128335	Tursiops truncatus	79.11	0.00e+00	3908.00
IUUC-Xtr-132524	Xenopus tropicalis	39.12	0.00e+00	1347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence