iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bdi-014075

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Protein HIRA

Genbank Nucleotide ID

CM000883

Gene Name

LOC100827726; BRADI_4g38470

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BRADI4G38470	BRADI4G38470.1	BRADI4G38470.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-22	78.9	123	160
UBD/Beta-Prp	4.60e-41	141.5	11	247

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+t+++W++  g ++
   Q: 123  GHTADVVDLNWsPDdSTLASGSLDNTVHIWSMANGICT 160
           8***********77799**************9988776 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw............ 79
           h+  +i ++++ p++  +atg+ d+++++w++++ ++           l+++ +h + v++v++ ++g +l++gs+D++i +             
   Q: 11   HEGLQIFSIDIQPGGLRFATGGGDQKVRIWNMKSVSKdnenddsnqrlLATIRDHFGSVNCVRWAKNGRYLASGSDDQAILIHekkagsgtsefg 105
           56677888999***********************999**********************************************999999888888 PP
   S: 80   .....dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl... 166
                d+++ k v+tl+gh+++v++l++sp++++l+sGs d+t+++w + +g c   +l+gh+++v +v+++p g+ ++s s+D+tv +W+    
   Q: 106  sgepaDIENWKVVMTLRGHTADVVDLNWSPDDSTLASGSLDNTVHIWSMANGICTA-VLRGHSSLVKGVTWDPIGSFIASQSDDKTVIIWRTsdw 199
           88888888************************************************.**********************************9555 PP
   S: 167  ...............................................k 167
                                                          +
   Q: 200  slahkteghwskslgstffrrlawspcghfittthgfqkprhsapvlE 247
           555555555555555555555555555555555555555555555555 PP

Organism

Brachypodium distachyon

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MLTEKPSWIR HEGLQIFSID IQPGGLRFAT GGGDQKVRIW NMKSVSKDNE NDDSNQRLLA 60
TIRDHFGSVN CVRWAKNGRY LASGSDDQAI LIHEKKAGSG TSEFGSGEPA DIENWKVVMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACGG AGAAGCCGAG CTGGATTCGC CATGAGGGCC TGCAGATCTT CTCCATCGAC 60
ATCCAGCCCG GCGGCCTCCG ATTCGCCACA GGCGGTGGCG ACCAGAAGGT GCCTAACCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

bdi:100827726

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	86.83	0.00e+00	1760.00
IUUC-Aml-001723	Ailuropoda melanoleuca	42.45	2.00e-83	303.00
IUUC-Atr-003132	Amborella trichopoda	67.74	0.00e+00	1372.00
IUUC-Apl-003197	Anas platyrhynchos	36.96	6.00e-84	305.00
IUUC-Aca-004733	Anolis carolinensis	37.38	5.00e-89	322.00
IUUC-Aly-005446	Arabidopsis lyrata	64.75	0.00e+00	1246.00
IUUC-Ath-007627	Arabidopsis thaliana	64.31	0.00e+00	1249.00
IUUC-Ago-007766	Ashbya gossypii	32.49	3.00e-60	226.00
IUUC-Acl-008104	Aspergillus clavatus	32.83	5.00e-71	262.00
IUUC-Afl-008591	Aspergillus flavus	31.58	4.00e-67	249.00
IUUC-Afu-008781	Aspergillus fumigatus	32.34	2.00e-63	237.00
IUUC-Ani-009272	Aspergillus nidulans	30.27	9.00e-57	214.00
IUUC-Ang-009655	Aspergillus niger	32.52	3.00e-69	256.00
IUUC-Aor-010119	Aspergillus oryzae	33.56	1.00e-66	248.00
IUUC-Ate-010530	Aspergillus terreus	29.55	8.00e-55	208.00
IUUC-Bgr-012237	Blumeria graminis	33.33	3.00e-65	243.00
IUUC-Bta-013320	Bos taurus	42.45	2.00e-83	303.00
IUUC-Bci-013795	Botrytis cinerea	31.48	3.00e-71	263.00
IUUC-Bol-016440	Brassica oleracea	65.16	0.00e+00	1259.00
IUUC-Bra-016651	Brassica rapa	64.39	0.00e+00	1219.00
IUUC-Cel-018692	Caenorhabditis elegans	27.48	5.00e-45	175.00
IUUC-Cja-018987	Callithrix jacchus	41.09	1.00e-74	273.00
IUUC-Cfa-020132	Canis familiaris	42.01	2.00e-83	303.00
IUUC-Cpo-021484	Cavia porcellus	42.60	2.00e-87	317.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	36.83	8.00e-73	268.00
IUUC-Csa-023081	Chlorocebus sabaeus	42.60	1.00e-87	317.00
IUUC-Cin-025182	Ciona intestinalis	37.10	4.00e-84	305.00
IUUC-Csv-026154	Ciona savignyi	38.94	4.00e-85	308.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	33.64	2.00e-65	243.00
IUUC-Cne-026891	Cryptococcus neoformans	41.21	2.00e-78	286.00
IUUC-Cme-027349	Cyanidioschyzon merolae	26.19	4.00e-62	232.00
IUUC-Dre-027655	Danio rerio	34.56	2.00e-83	303.00
IUUC-Dno-029557	Dasypus novemcinctus	41.90	2.00e-69	256.00
IUUC-Dor-030687	Dipodomys ordii	35.71	8.00e-66	244.00
IUUC-Dse-031334	Dothistroma septosporum	27.40	1.00e-87	317.00
IUUC-Dme-031746	Drosophila melanogaster	39.90	6.00e-86	311.00
IUUC-Ete-032384	Echinops telfairi	32.66	7.00e-63	235.00
IUUC-Eca-033430	Equus caballus	36.90	3.00e-83	302.00
IUUC-Fca-036121	Felis catus	42.56	5.00e-85	308.00
IUUC-Fal-036817	Ficedula albicollis	42.19	4.00e-83	302.00
IUUC-Fox-037906	Fusarium oxysporum	34.67	3.00e-70	258.00
IUUC-Fso-038409	Fusarium solani	35.14	2.00e-69	257.00
IUUC-Gmo-039151	Gadus morhua	40.79	2.00e-83	303.00
IUUC-Ggr-040016	Gaeumannomyces graminis	35.28	2.00e-69	257.00
IUUC-Gga-040936	Gallus gallus	36.68	1.00e-87	317.00
IUUC-Gac-041405	Gasterosteus aculeatus	40.42	1.00e-80	293.00
IUUC-Gma-044252	Glycine max	72.33	0.00e+00	1437.00
IUUC-Ggo-045430	Gorilla gorilla	42.60	1.00e-87	317.00
IUUC-Hsa-046442	Homo sapiens	42.60	1.00e-87	317.00
IUUC-Hvu-047587	Hordeum vulgare	90.81	0.00e+00	1701.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	43.04	2.00e-65	241.00
IUUC-Kpa-049145	Komagataella pastoris	30.84	8.00e-57	214.00
IUUC-Lch-050474	Latimeria chalumnae	36.89	2.00e-83	303.00
IUUC-Lpe-051209	Leersia perrieri	85.11	0.00e+00	1694.00
IUUC-Loc-052119	Lepisosteus oculatus	36.22	2.00e-81	296.00
IUUC-Lma-053237	Leptosphaeria maculans	33.81	3.00e-67	249.00
IUUC-Laf-053718	Loxodonta africana	37.92	8.00e-88	318.00
IUUC-Mcc-055621	Macaca mulatta	40.80	5.00e-74	272.00
IUUC-Meu-055914	Macropus eugenii	38.27	7.00e-57	215.00
IUUC-Mor-057090	Magnaporthe oryzae	35.82	2.00e-68	253.00
IUUC-Mpo-057364	Magnaporthe poae	33.92	2.00e-69	257.00
IUUC-Mtr-057744	Medicago truncatula	71.52	0.00e+00	1410.00
IUUC-Mla-058914	Melampsora laricipopulina	26.25	2.00e-78	286.00
IUUC-Mga-060181	Meleagris gallopavo	36.69	2.00e-83	303.00
IUUC-Mvi-060432	Microbotryum violaceum	34.52	3.00e-59	223.00
IUUC-Mmr-060871	Microcebus murinus	38.12	1.00e-88	320.00
IUUC-Mdo-062301	Monodelphis domestica	37.48	2.00e-87	316.00
IUUC-Mmu-063888	Mus musculus	42.86	6.00e-88	318.00
IUUC-Mac-064768	Musa acuminata	71.50	0.00e+00	1413.00
IUUC-Mpu-066732	Mustela putorius furo	42.45	2.00e-83	303.00
IUUC-Mlu-067542	Myotis lucifugus	41.94	6.00e-84	305.00
IUUC-Nfi-068396	Neosartorya fischeri	32.26	3.00e-63	236.00
IUUC-Ncr-068842	Neurospora crassa	33.08	4.00e-71	262.00
IUUC-Nle-070156	Nomascus leucogenys	42.60	1.00e-87	317.00
IUUC-Opr-070808	Ochotona princeps	41.06	6.00e-53	201.00
IUUC-Ont-072105	Oreochromis niloticus	37.23	7.00e-83	301.00
IUUC-Ocu-074962	Oryctolagus cuniculus	35.78	8.00e-84	304.00
IUUC-Oba-075178	Oryza barthii	86.33	0.00e+00	1657.00
IUUC-Obr-076399	Oryza brachyantha	86.66	0.00e+00	1694.00
IUUC-Ogu-078797	Oryza glumaepatula	86.33	0.00e+00	1657.00
IUUC-Oin-080085	Oryza indica	85.93	0.00e+00	1570.00
IUUC-Olo-081048	Oryza longistaminata	84.54	0.00e+00	712.00
IUUC-Ome-081324	Oryza meridionalis	87.06	0.00e+00	1656.00
IUUC-Oni-082548	Oryza nivara	86.33	0.00e+00	1654.00
IUUC-Opu-084008	Oryza punctata	90.04	0.00e+00	860.00
IUUC-Oru-084339	Oryza rufipogon	86.22	0.00e+00	1655.00
IUUC-Osa-085782	Oryza sativa	86.22	0.00e+00	1655.00
IUUC-Ola-087302	Oryzias latipes	33.93	6.00e-79	288.00
IUUC-Olu-087611	Ostreococcus lucimarinus	39.93	3.00e-113	402.00
IUUC-Oga-087935	Otolemur garnettii	37.93	2.00e-83	303.00
IUUC-Oar-089229	Ovis aries	37.53	3.00e-66	246.00
IUUC-Ptr-090715	Pan troglodytes	42.60	1.00e-87	317.00
IUUC-Pan-092318	Papio anubis	42.12	1.00e-83	304.00
IUUC-Psi-094053	Pelodiscus sinensis	37.50	8.00e-84	304.00
IUUC-Pno-094985	Phaeosphaeria nodorum	32.09	6.00e-61	228.00
IUUC-Ppa-095499	Physcomitrella patens	49.17	0.00e+00	916.00
IUUC-Pfo-096857	Poecilia formosa	40.46	4.00e-79	289.00
IUUC-Pab-098047	Pongo abelii	42.60	1.00e-87	317.00
IUUC-Pop-099587	Populus trichocarpa	69.62	0.00e+00	1383.00
IUUC-Pca-100558	Procavia capensis	49.74	5.00e-50	192.00
IUUC-Ppe-101261	Prunus persica	70.96	0.00e+00	1402.00
IUUC-Pva-102683	Pteropus vampyrus	42.35	9.00e-85	307.00
IUUC-Pgr-103660	Puccinia graminis	36.10	2.00e-60	226.00
IUUC-Ptt-103900	Puccinia triticina	30.75	5.00e-60	225.00
IUUC-Pte-104209	Pyrenophora teres	33.41	2.00e-70	260.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.41	8.00e-70	258.00
IUUC-Rno-105566	Rattus norvegicus	42.60	2.00e-87	317.00
IUUC-Sce-106291	Saccharomyces cerevisiae	27.07	2.00e-64	239.00
IUUC-Sha-107514	Sarcophilus harrisii	34.78	9.00e-72	264.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	32.94	3.00e-70	259.00
IUUC-Spo-108162	Schizosaccharomyces pombe	33.78	4.00e-74	272.00
IUUC-Smo-109186	Selaginella moellendorffii	50.56	0.00e+00	912.00
IUUC-Sit-110730	Setaria italica	84.91	0.00e+00	1699.00
IUUC-Sly-111547	Solanum lycopersicum	68.89	0.00e+00	1338.00
IUUC-Stu-112705	Solanum tuberosum	69.10	0.00e+00	1342.00
IUUC-Sar-113222	Sorex araneus	36.23	1.00e-75	277.00
IUUC-Sbi-114272	Sorghum bicolor	84.05	0.00e+00	1644.00
IUUC-Sre-115061	Sporisorium reilianum	33.13	1.00e-69	257.00
IUUC-Ssc-116364	Sus scrofa	41.93	3.00e-83	302.00
IUUC-Tgu-116645	Taeniopygia guttata	36.67	2.00e-83	303.00
IUUC-Tru-117590	Takifugu rubripes	36.73	2.00e-86	313.00
IUUC-Tsy-119212	Tarsius syrichta	42.86	4.00e-72	265.00
IUUC-Tni-119915	Tetraodon nigroviridis	36.31	3.00e-85	309.00
IUUC-Tca-121765	Theobroma cacao	71.09	0.00e+00	1404.00
IUUC-Tre-121887	Trichoderma reesei	35.05	1.00e-63	238.00
IUUC-Tvi-122262	Trichoderma virens	35.28	1.00e-63	238.00
IUUC-Tae-123009	Triticum aestivum	88.50	0.00e+00	1182.00
IUUC-Tur-126483	Triticum urartu	89.98	0.00e+00	1780.00
IUUC-Tme-127202	Tuber melanosporum	28.98	4.00e-50	192.00
IUUC-Tbe-127350	Tupaia belangeri	34.36	8.00e-50	191.00
IUUC-Ttr-129077	Tursiops truncatus	33.93	6.00e-73	268.00
IUUC-Uma-129465	Ustilago maydis	35.36	2.00e-72	267.00
IUUC-Vda-129844	Verticillium dahliae	32.87	3.00e-67	249.00
IUUC-Vvi-131397	Vitis vinifera	71.02	0.00e+00	1431.00
IUUC-Xtr-132057	Xenopus tropicalis	37.08	4.00e-88	318.00
IUUC-Xma-134139	Xiphophorus maculatus	38.51	4.00e-67	248.00
IUUC-Yli-134424	Yarrowia lipolytica	35.31	1.00e-66	248.00
IUUC-Zma-135839	Zea mays	83.54	0.00e+00	1653.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence