iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116645

Ensembl Protein ID

ENSTGUP00000008820.1

UniProt Accession

H0ZE08; H0ZE08_TAEGU

Genbank Protein ID

ENSTGUP00000008820

Protein Name

Protein HIRA

Genbank Nucleotide ID

ABQF01029282

Gene Name

HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008538.1	ENSTGUT00000008914.1	ENSTGUP00000008820.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-19	68.4	57	86

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 57   HLACVNCVRWsNNgVYLASGGDDKLIMVWK 86
           8899******9777***************7 PP

Organism

Taeniopygia guttata

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

GKPIFSVDIH PDGTKFATGG QGQDSGKVVI WNMAPVLKEE DEKNENIPKM LCQMDNHLAC 60
VNCVRWSNNG VYLASGGDDK LIMVWKRAAY IGPSTVFGSS SKLTNVEQWR CVSILRSHSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAGCCAA TATTTTCAGT GGACATTCAC CCAGATGGGA CCAAGTTTGC AACAGGAGGA 60
CAAGGTAAGT CTGTGTACTG GTAAAAGGCA GAGTTTTGGA TAATAGTAGT AGTAGTAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000790--C:nuclear chromatin
GO:0043234--C:protein complex
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0007369--P:gastrulation
GO:0042692--P:muscle cell differentiation
GO:0001649--P:osteoblast differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	35.24	8.00e-84	305.00
IUUC-Aml-001723	Ailuropoda melanoleuca	83.96	0.00e+00	1588.00
IUUC-Atr-003132	Amborella trichopoda	36.54	4.00e-84	306.00
IUUC-Apl-003197	Anas platyrhynchos	97.43	0.00e+00	1825.00
IUUC-Aca-004733	Anolis carolinensis	87.75	0.00e+00	1684.00
IUUC-Aly-005446	Arabidopsis lyrata	39.27	7.00e-77	281.00
IUUC-Ath-007627	Arabidopsis thaliana	40.73	7.00e-81	295.00
IUUC-Ago-007766	Ashbya gossypii	31.05	6.00e-58	218.00
IUUC-Acl-008104	Aspergillus clavatus	29.86	9.00e-62	231.00
IUUC-Afl-008591	Aspergillus flavus	29.93	7.00e-61	228.00
IUUC-Afu-008781	Aspergillus fumigatus	34.05	2.00e-58	220.00
IUUC-Ani-009272	Aspergillus nidulans	33.16	2.00e-54	207.00
IUUC-Ang-009655	Aspergillus niger	34.22	6.00e-62	232.00
IUUC-Aor-010119	Aspergillus oryzae	29.93	2.00e-61	230.00
IUUC-Ate-010530	Aspergillus terreus	28.40	3.00e-55	210.00
IUUC-Ame-011147	Astyanax mexicanus	89.89	2.00e-47	179.00
IUUC-Bgr-012237	Blumeria graminis	34.46	7.00e-61	228.00
IUUC-Bta-013320	Bos taurus	81.62	0.00e+00	1626.00
IUUC-Bci-013795	Botrytis cinerea	33.77	9.00e-64	238.00
IUUC-Bdi-014075	Brachypodium distachyon	36.67	8.00e-88	318.00
IUUC-Bol-016440	Brassica oleracea	33.10	5.00e-84	305.00
IUUC-Bra-016651	Brassica rapa	36.23	7.00e-83	301.00
IUUC-Cel-018692	Caenorhabditis elegans	38.04	1.00e-73	270.00
IUUC-Cja-018987	Callithrix jacchus	84.40	0.00e+00	1516.00
IUUC-Cfa-020132	Canis familiaris	83.86	0.00e+00	1587.00
IUUC-Cpo-021484	Cavia porcellus	83.86	0.00e+00	1583.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	34.58	6.00e-58	219.00
IUUC-Csa-023081	Chlorocebus sabaeus	84.46	0.00e+00	1587.00
IUUC-Cin-025182	Ciona intestinalis	54.06	2.00e-153	536.00
IUUC-Csv-026154	Ciona savignyi	55.60	2.00e-147	516.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	30.15	2.00e-63	237.00
IUUC-Cne-026891	Cryptococcus neoformans	42.00	9.00e-82	298.00
IUUC-Cme-027349	Cyanidioschyzon merolae	29.02	8.00e-52	198.00
IUUC-Dre-027655	Danio rerio	71.20	0.00e+00	1366.00
IUUC-Dno-029557	Dasypus novemcinctus	74.57	0.00e+00	982.00
IUUC-Dor-030687	Dipodomys ordii	80.91	0.00e+00	691.00
IUUC-Dse-031334	Dothistroma septosporum	30.89	3.00e-61	229.00
IUUC-Dme-031746	Drosophila melanogaster	54.45	8.00e-152	530.00
IUUC-Ete-032384	Echinops telfairi	80.00	0.00e+00	1506.00
IUUC-Eca-033430	Equus caballus	83.47	0.00e+00	1571.00
IUUC-Fca-036121	Felis catus	84.06	0.00e+00	1585.00
IUUC-Fal-036817	Ficedula albicollis	98.71	0.00e+00	1867.00
IUUC-Fox-037906	Fusarium oxysporum	34.84	8.00e-66	244.00
IUUC-Fso-038409	Fusarium solani	31.77	1.00e-64	241.00
IUUC-Gmo-039151	Gadus morhua	87.19	0.00e+00	685.00
IUUC-Ggr-040016	Gaeumannomyces graminis	35.71	2.00e-67	250.00
IUUC-Gga-040936	Gallus gallus	97.03	0.00e+00	1887.00
IUUC-Gac-041405	Gasterosteus aculeatus	63.66	0.00e+00	1204.00
IUUC-Gma-042800	Glycine max	35.44	1.00e-84	308.00
IUUC-Ggo-045430	Gorilla gorilla	84.47	0.00e+00	1583.00
IUUC-Hsa-046442	Homo sapiens	84.36	0.00e+00	1584.00
IUUC-Hvu-047587	Hordeum vulgare	37.12	5.00e-79	288.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	95.33	3.00e-169	586.00
IUUC-Kpa-049145	Komagataella pastoris	31.36	4.00e-59	223.00
IUUC-Lch-050474	Latimeria chalumnae	78.04	0.00e+00	1470.00
IUUC-Lpe-051209	Leersia perrieri	36.09	6.00e-81	295.00
IUUC-Loc-052119	Lepisosteus oculatus	73.48	0.00e+00	1395.00
IUUC-Lma-053237	Leptosphaeria maculans	35.64	7.00e-64	238.00
IUUC-Laf-053718	Loxodonta africana	85.64	0.00e+00	1610.00
IUUC-Mcc-055621	Macaca mulatta	84.29	0.00e+00	1516.00
IUUC-Meu-055914	Macropus eugenii	80.93	0.00e+00	1474.00
IUUC-Mor-057090	Magnaporthe oryzae	33.33	5.00e-64	239.00
IUUC-Mpo-057364	Magnaporthe poae	35.97	1.00e-68	254.00
IUUC-Mtr-057744	Medicago truncatula	36.67	1.00e-84	307.00
IUUC-Mla-058914	Melampsora laricipopulina	41.97	3.00e-82	299.00
IUUC-Mga-060181	Meleagris gallopavo	94.17	0.00e+00	1853.00
IUUC-Mvi-060432	Microbotryum violaceum	38.50	2.00e-74	273.00
IUUC-Mmr-060871	Microcebus murinus	84.27	0.00e+00	1623.00
IUUC-Mdo-062301	Monodelphis domestica	87.34	0.00e+00	1634.00
IUUC-Mmu-063888	Mus musculus	84.08	0.00e+00	1568.00
IUUC-Mac-065137	Musa acuminata	36.74	9.00e-86	311.00
IUUC-Mpu-066732	Mustela putorius furo	83.96	0.00e+00	1606.00
IUUC-Mlu-067542	Myotis lucifugus	83.85	0.00e+00	1561.00
IUUC-Nfi-068396	Neosartorya fischeri	34.75	2.00e-58	220.00
IUUC-Ncr-068842	Neurospora crassa	32.75	6.00e-66	245.00
IUUC-Nle-070156	Nomascus leucogenys	84.87	0.00e+00	1595.00
IUUC-Opr-070808	Ochotona princeps	82.84	0.00e+00	1278.00
IUUC-Ont-072105	Oreochromis niloticus	69.59	0.00e+00	1352.00
IUUC-Ocu-074962	Oryctolagus cuniculus	84.16	0.00e+00	1599.00
IUUC-Oba-075178	Oryza barthii	41.67	1.00e-86	314.00
IUUC-Obr-076399	Oryza brachyantha	36.49	1.00e-88	320.00
IUUC-Ogu-078797	Oryza glumaepatula	41.67	1.00e-86	314.00
IUUC-Oin-080085	Oryza indica	40.62	4.00e-77	282.00
IUUC-Olo-081048	Oryza longistaminata	40.72	4.00e-66	246.00
IUUC-Ome-081324	Oryza meridionalis	41.67	1.00e-86	314.00
IUUC-Oni-082548	Oryza nivara	41.67	1.00e-86	314.00
IUUC-Opu-084008	Oryza punctata	41.67	1.00e-86	314.00
IUUC-Oru-084339	Oryza rufipogon	41.41	4.00e-86	312.00
IUUC-Osa-085782	Oryza sativa	41.41	4.00e-86	312.00
IUUC-Ola-087302	Oryzias latipes	70.45	0.00e+00	787.00
IUUC-Olu-087611	Ostreococcus lucimarinus	35.84	5.00e-88	318.00
IUUC-Oga-087935	Otolemur garnettii	84.32	0.00e+00	1567.00
IUUC-Oar-089229	Ovis aries	63.04	0.00e+00	991.00
IUUC-Ptr-090715	Pan troglodytes	84.36	0.00e+00	1584.00
IUUC-Pan-092318	Papio anubis	84.39	0.00e+00	1583.00
IUUC-Psi-094053	Pelodiscus sinensis	92.79	0.00e+00	1787.00
IUUC-Pno-094985	Phaeosphaeria nodorum	33.51	4.00e-57	216.00
IUUC-Ppa-095819	Physcomitrella patens	36.03	1.00e-86	314.00
IUUC-Pfo-096857	Poecilia formosa	68.35	0.00e+00	1305.00
IUUC-Pab-098047	Pongo abelii	84.46	0.00e+00	1588.00
IUUC-Pop-099587	Populus trichocarpa	37.53	5.00e-85	309.00
IUUC-Pca-100558	Procavia capensis	84.47	0.00e+00	679.00
IUUC-Ppe-101261	Prunus persica	36.72	1.00e-86	314.00
IUUC-Pva-102683	Pteropus vampyrus	83.98	0.00e+00	1600.00
IUUC-Pgr-103660	Puccinia graminis	40.92	2.00e-74	273.00
IUUC-Ptt-103900	Puccinia triticina	34.77	2.00e-76	280.00
IUUC-Pte-104209	Pyrenophora teres	35.64	2.00e-63	237.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	35.64	1.00e-62	234.00
IUUC-Rno-105137	Rattus norvegicus	83.58	0.00e+00	1570.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.90	3.00e-61	229.00
IUUC-Sha-107514	Sarcophilus harrisii	83.04	0.00e+00	1539.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	36.06	5.00e-78	285.00
IUUC-Spo-108162	Schizosaccharomyces pombe	39.15	5.00e-78	285.00
IUUC-Smo-109186	Selaginella moellendorffii	40.05	8.00e-85	308.00
IUUC-Sit-110730	Setaria italica	37.07	3.00e-88	319.00
IUUC-Sly-111547	Solanum lycopersicum	37.42	2.00e-87	317.00
IUUC-Stu-112705	Solanum tuberosum	37.42	9.00e-88	318.00
IUUC-Sar-113222	Sorex araneus	78.89	0.00e+00	1399.00
IUUC-Sbi-114272	Sorghum bicolor	37.70	8.00e-91	328.00
IUUC-Sre-115061	Sporisorium reilianum	34.56	1.00e-74	274.00
IUUC-Ssc-116364	Sus scrofa	82.20	0.00e+00	1642.00
IUUC-Tru-117590	Takifugu rubripes	67.87	0.00e+00	1309.00
IUUC-Tsy-119212	Tarsius syrichta	79.42	0.00e+00	877.00
IUUC-Tni-119915	Tetraodon nigroviridis	67.38	0.00e+00	1277.00
IUUC-Tca-121765	Theobroma cacao	35.90	6.00e-85	308.00
IUUC-Tre-121887	Trichoderma reesei	34.02	2.00e-56	214.00
IUUC-Tvi-122262	Trichoderma virens	34.02	2.00e-56	213.00
IUUC-Tae-124148	Triticum aestivum	44.57	9.00e-34	138.00
IUUC-Tur-126483	Triticum urartu	37.58	6.00e-88	318.00
IUUC-Tme-127202	Tuber melanosporum	29.98	7.00e-55	208.00
IUUC-Tbe-127350	Tupaia belangeri	77.24	3.00e-172	598.00
IUUC-Ttr-129077	Tursiops truncatus	79.39	0.00e+00	1582.00
IUUC-Uma-129465	Ustilago maydis	35.95	5.00e-77	282.00
IUUC-Vda-129844	Verticillium dahliae	34.96	2.00e-63	236.00
IUUC-Vvi-131397	Vitis vinifera	35.87	4.00e-86	312.00
IUUC-Xtr-132057	Xenopus tropicalis	75.40	0.00e+00	1426.00
IUUC-Xma-134139	Xiphophorus maculatus	70.37	0.00e+00	831.00
IUUC-Yli-134424	Yarrowia lipolytica	31.23	5.00e-62	232.00
IUUC-Zma-135839	Zea mays	42.19	3.00e-88	319.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence