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Tag Content
iUUCD ID IUUC-Bol-015618
Ensembl Protein ID Bo9g163990.1
UniProt Accession A0A0D3EF99; A0A0D3EF99_BRAOL
Protein Name Ribosome biogenesis protein WDR12 homolog
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
Bo9g163990 Bo9g163990.1 Bo9g163990.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-30 105.5 352 386
UBD/Beta-Prp 1.40e-40 140.9 105 299
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
    H+++++++++ s+ +l+s+s+Dg+i++WDlrt
   Q: 352 HASWISACKWhkSSwFHLLSASYDGKIMLWDLRTA 386
    9**********977688***************986 PP
   


   UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk....ilvtgseDrtikvwdls.........tgkcvhtlkg 92
    h++ +++v+ ++++++tg++dg ++w+ + ++ + l+gh+++++++ f +++ + +t+++Drt++++ ++ +l+g
   Q: 105 HDDWVSAVDG-SSSRFILTGCYDGLGRIWSSPE-SCTHILEGHSGAISSIAFVNSEGaenvTVATAAKDRTLRLFKVDtaesgdpttRVGAYKILRG 199
    5666666666.67899*************9877.999***************999888999**************666666666555555677889* PP
   S: 93 hedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl 166
    h++sv s++ +++g+k+ sGs+d ti++wd+++ + + t+ gh++ v++vv+++ +++ s+s D vr Wd+
   Q: 200 HKASVASVAAQKYGSKICSGSWDCTINLWDTDEATSELSvagkrrkgnnqaeetqlegeaesTFVGHTQCVSSVVWPE-HDVIYSCSWDHSVRRWDV 295
    *********************************9999999************************************99.8999************** PP
   S: 167 ktgk 170
    +tgk
   Q: 296 PTGK 299
    9986 PP
   

Organism Brassica oleracea
Functional Description
(View)

Functional Description



     Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Protein Sequence
(Fasta)
MDGGGEDASK VIHVKFVTKL DSPFQVPSSS VVIPSNVTRL GLSSIVNSLL TLEKHEAFDF 60
LIDGELIRMS LEQFLLAKGI SAERTLEIEY IRAVAPRKEE KPSLHDDWVS AVDGSSSRFI 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Bol-015618|E3,WD_repeat;UBD,Beta-Prp|Brassica oleracea
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACGGCG GAGGAGAAGA CGCGTCTAAA GTAATCCACG TGAAGTTCGT GACGAAGCTT 60
GACTCACCGT TCCAAGTTCC GTCCAGCTCC GTGGTTATCC CTTCCAATGT CACTCGTCTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Bol-015618|E3,WD_repeat;UBD,Beta-Prp|Brassica oleracea
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Bra-017876 Brassica rapa 98.36 0.00e+00 860.00
IUUC-Cel-018569 Caenorhabditis elegans 23.61 2.00e-23 102.00
IUUC-Cin-025789 Ciona intestinalis 30.81 2.00e-47 183.00
IUUC-Dre-027907 Danio rerio 34.57 3.00e-63 235.00
IUUC-Dse-031308 Dothistroma septosporum 31.65 8.00e-49 187.00
IUUC-Ggr-040093 Gaeumannomyces graminis 25.96 2.00e-26 113.00
IUUC-Mor-057114 Magnaporthe oryzae 27.29 1.00e-36 147.00
IUUC-Mla-059107 Melampsora laricipopulina 27.27 8.00e-39 154.00
IUUC-Mga-059745 Meleagris gallopavo 34.63 2.00e-56 213.00
IUUC-Mvi-060362 Microbotryum violaceum 23.80 3.00e-28 119.00
IUUC-Mmu-063546 Mus musculus 33.50 7.00e-54 204.00
IUUC-Oan-073453 Ornithorhynchus anatinus 34.64 5.00e-63 234.00
IUUC-Psi-093504 Pelodiscus sinensis 33.91 1.00e-56 213.00
IUUC-Pfo-096337 Poecilia formosa 34.31 3.00e-61 228.00
IUUC-Pva-102921 Pteropus vampyrus 33.64 1.00e-23 103.00
IUUC-Pgr-103637 Puccinia graminis 25.53 8.00e-35 141.00
IUUC-Sar-113596 Sorex araneus 30.27 2.00e-41 162.00
IUUC-Tbe-127736 Tupaia belangeri 27.47 8.00e-27 114.00
Created Date 25-Jun-2017

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