iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013567

Ensembl Protein ID

ENSBTAP00000049772.2

UniProt Accession

F1ML16; F1ML16_BOVIN

Genbank Protein ID

ENSBTAP00000049772

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02048667

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000025130.4	ENSBTAT00000055247.2	ENSBTAP00000049772.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-12	48.0	170	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 170  CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 229
           9*****************************77.......4566677678****************98 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

KYVHRNIQLK TPISVGLAGP GLGTPGGHIW KAEWSSSSSA SLHPRCAGRR PWLCRAKYRT 60
AARWRHSCSS ARRPGPLQIR VCGKRGGAET RPGRGEDGPA GQTDRGPGGR RAAQRSHVPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATATGTAC ACAGGAACAT TCAGCTCAAA ACCCCAATTT CTGTGGGGCT CGCAGGTCCG 60
GGGCTGGGGA CTCCAGGTGG GCACATCTGG AAGGCTGAAT CTGAGAACAG GCCCCCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	92.38	3.00e-152	532.00
IUUC-Aca-004680	Anolis carolinensis	74.48	8.00e-68	251.00
IUUC-Ame-010967	Astyanax mexicanus	60.24	1.00e-93	337.00
IUUC-Cja-019621	Callithrix jacchus	89.71	9.00e-60	221.00
IUUC-Cfa-020731	Canis familiaris	98.04	8.00e-171	593.00
IUUC-Cpo-021326	Cavia porcellus	92.11	4.00e-167	581.00
IUUC-Csa-023645	Chlorocebus sabaeus	97.58	3.00e-164	572.00
IUUC-Dre-028027	Danio rerio	57.64	4.00e-91	328.00
IUUC-Dno-028900	Dasypus novemcinctus	95.84	4.00e-162	565.00
IUUC-Fca-035394	Felis catus	94.85	7.00e-59	218.00
IUUC-Fal-036980	Ficedula albicollis	62.47	3.00e-110	392.00
IUUC-Gga-040708	Gallus gallus	70.61	7.00e-105	374.00
IUUC-Gac-041742	Gasterosteus aculeatus	77.49	8.00e-78	284.00
IUUC-Ggo-044591	Gorilla gorilla	100.00	1.00e-139	490.00
IUUC-Hsa-046769	Homo sapiens	97.80	7.00e-161	560.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	97.50	1.00e-173	603.00
IUUC-Loc-051883	Lepisosteus oculatus	63.47	7.00e-93	334.00
IUUC-Laf-053358	Loxodonta africana	93.36	6.00e-165	574.00
IUUC-Mcc-054981	Macaca mulatta	97.58	3.00e-164	572.00
IUUC-Meu-056181	Macropus eugenii	89.80	2.00e-59	223.00
IUUC-Mga-059592	Meleagris gallopavo	73.54	5.00e-102	364.00
IUUC-Mmr-061560	Microcebus murinus	95.62	6.00e-163	567.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	2.00e-90	326.00
IUUC-Mmu-064258	Mus musculus	95.83	6.00e-160	558.00
IUUC-Mpu-065911	Mustela putorius furo	98.46	4.00e-168	585.00
IUUC-Mlu-067575	Myotis lucifugus	80.16	0.00e+00	635.00
IUUC-Ont-072493	Oreochromis niloticus	65.97	4.00e-80	292.00
IUUC-Ola-086584	Oryzias latipes	61.66	8.00e-89	321.00
IUUC-Oga-088774	Otolemur garnettii	96.57	1.00e-166	580.00
IUUC-Ptr-090491	Pan troglodytes	100.00	2.00e-121	429.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	59.16	2.00e-86	313.00
IUUC-Pab-098488	Pongo abelii	94.97	0.00e+00	803.00
IUUC-Pca-100667	Procavia capensis	96.61	1.00e-141	497.00
IUUC-Pva-102421	Pteropus vampyrus	97.36	4.00e-165	575.00
IUUC-Rno-105528	Rattus norvegicus	96.26	6.00e-152	531.00
IUUC-Sar-113478	Sorex araneus	99.17	5.00e-119	421.00
IUUC-Ssc-115420	Sus scrofa	91.23	2.00e-168	586.00
IUUC-Tgu-116642	Taeniopygia guttata	71.88	2.00e-106	379.00
IUUC-Tru-118583	Takifugu rubripes	60.44	7.00e-85	308.00
IUUC-Xtr-132210	Xenopus tropicalis	57.08	1.00e-110	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence