iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053618

UUCD1 version

UUC-LoA-00149

Ensembl Protein ID

ENSLAFP00000003642.3

UniProt Accession

G3SU47; G3SU47_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000004367.3	ENSLAFT00000004368.3	ENSLAFP00000003642.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.54	0.00e+00	1916.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

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Nucleotide Sequence
(Fasta)

ATGCCTGTAC AAGCTCCACA ATGGACGGAT TTCCTCTCCT GCCCAATTTG CACTCAGACT 60
TTCGACGAAA CAATTCGAAA GCCCATCAGT TTGGGCTGTG GCCATACTGT CTGCAAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	96.80	0.00e+00	1911.00
IUUC-Apl-003290	Anas platyrhynchos	87.56	0.00e+00	1797.00
IUUC-Aca-004905	Anolis carolinensis	85.46	0.00e+00	1683.00
IUUC-Ame-011475	Astyanax mexicanus	77.89	0.00e+00	918.00
IUUC-Cja-019907	Callithrix jacchus	96.90	0.00e+00	1963.00
IUUC-Cfa-020679	Canis familiaris	96.98	0.00e+00	1914.00
IUUC-Cpo-022110	Cavia porcellus	92.90	0.00e+00	1915.00
IUUC-Csa-024166	Chlorocebus sabaeus	97.51	0.00e+00	1934.00
IUUC-Dno-029870	Dasypus novemcinctus	95.98	0.00e+00	983.00
IUUC-Dor-030934	Dipodomys ordii	87.03	0.00e+00	1487.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	2.00e-162	566.00
IUUC-Ete-032652	Echinops telfairi	96.77	0.00e+00	1398.00
IUUC-Eca-033236	Equus caballus	96.53	0.00e+00	1919.00
IUUC-Eeu-035091	Erinaceus europaeus	83.30	0.00e+00	877.00
IUUC-Fca-035773	Felis catus	97.08	0.00e+00	1913.00
IUUC-Fal-036972	Ficedula albicollis	86.00	0.00e+00	1789.00
IUUC-Gmo-039303	Gadus morhua	80.07	0.00e+00	891.00
IUUC-Ggo-044691	Gorilla gorilla	90.92	0.00e+00	1805.00
IUUC-Hsa-046163	Homo sapiens	97.53	0.00e+00	1975.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	93.18	0.00e+00	1013.00
IUUC-Lch-050667	Latimeria chalumnae	75.23	0.00e+00	1499.00
IUUC-Loc-052404	Lepisosteus oculatus	69.26	0.00e+00	1329.00
IUUC-Mcc-054692	Macaca mulatta	97.53	0.00e+00	1976.00
IUUC-Meu-056025	Macropus eugenii	85.76	0.00e+00	895.00
IUUC-Mmr-061188	Microcebus murinus	97.71	0.00e+00	1930.00
IUUC-Mdo-063035	Monodelphis domestica	92.81	0.00e+00	1856.00
IUUC-Mmu-064146	Mus musculus	93.14	0.00e+00	1880.00
IUUC-Mpu-066217	Mustela putorius furo	96.34	0.00e+00	1899.00
IUUC-Mlu-068023	Myotis lucifugus	95.25	0.00e+00	1910.00
IUUC-Nle-069506	Nomascus leucogenys	97.53	0.00e+00	1975.00
IUUC-Opr-070587	Ochotona princeps	83.26	0.00e+00	1567.00
IUUC-Ont-071278	Oreochromis niloticus	78.33	0.00e+00	892.00
IUUC-Oan-073500	Ornithorhynchus anatinus	91.26	0.00e+00	1863.00
IUUC-Ocu-074299	Oryctolagus cuniculus	96.44	0.00e+00	1837.00
IUUC-Ola-086665	Oryzias latipes	78.82	0.00e+00	905.00
IUUC-Oga-088519	Otolemur garnettii	90.15	0.00e+00	1719.00
IUUC-Oar-089246	Ovis aries	96.19	0.00e+00	1795.00
IUUC-Ptr-091102	Pan troglodytes	97.63	0.00e+00	1976.00
IUUC-Pan-091952	Papio anubis	97.45	0.00e+00	1973.00
IUUC-Pfo-097227	Poecilia formosa	62.84	0.00e+00	1142.00
IUUC-Pab-097975	Pongo abelii	94.06	0.00e+00	1877.00
IUUC-Pca-101127	Procavia capensis	93.45	0.00e+00	1301.00
IUUC-Pva-102431	Pteropus vampyrus	87.88	0.00e+00	1682.00
IUUC-Ptt-103758	Puccinia triticina	40.43	3.00e-05	42.00
IUUC-Sha-106690	Sarcophilus harrisii	91.81	0.00e+00	1843.00
IUUC-Ssc-116189	Sus scrofa	96.99	0.00e+00	1855.00
IUUC-Tgu-116527	Taeniopygia guttata	87.02	0.00e+00	1803.00
IUUC-Tru-118389	Takifugu rubripes	62.88	0.00e+00	1185.00
IUUC-Tsy-119193	Tarsius syrichta	94.26	0.00e+00	1857.00
IUUC-Tni-119790	Tetraodon nigroviridis	80.84	0.00e+00	872.00
IUUC-Tbe-127445	Tupaia belangeri	90.80	0.00e+00	1532.00
IUUC-Ttr-128877	Tursiops truncatus	96.45	0.00e+00	1849.00
IUUC-Xtr-132274	Xenopus tropicalis	78.92	0.00e+00	1548.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence