iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027902

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 43b

Genbank Nucleotide ID

BX120006

Gene Name

usp43b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000088072.2	ENSDART00000122735.2	ENSDARP00000106880.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.10e-94	315.3	117	762

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp.........kepkgellkslqklfeelwkskkkavsprellkalkke 80
           GlkN+gNtC+mN+v+QcLsn+  l+e+l   ++k+++ ++           +++kge+++ l+ l+++lw+ + +     e++ +++k+
   Q: 117  GLKNHGNTCFMNAVVQCLSNTDLLAEYLGLeRYKRDVCHNGIngfirngngQNEKGEVTERLAVLVRALWTFQYTPQLSAEFKMTVSKY 205
           9**************************965467777766655888888888************************************** PP
   S: 81   aeefsgyeqqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde.aeekkkkknkslisdlFqgqlksqikclecd 160
             +f+g++q+Da Efl +lld+l+e+ ++        +k+k+k +e +++k  ++    ++ ++   +s++++ Fq q+ks+++c++c 
   Q: 206  GAQFRGNSQHDALEFLLWLLDRLHEDSTSvvpngnniNKSKNKGQEGGDEKPGSDTLsPPQTQPGVRHSFVQEHFQAQYKSSLTCPHCL 294
           ***************************88887777555555555555555555555544556666777********************* PP
   S: 161  nvssreepfldlslpvpgkeetkke................................................................ 185
           ++s++++pfl +slp+p ++++                                                                   
   Q: 295  KQSNTFDPFLCISLPIPLRQTRP-Vcvtlvfsskgqrylrvglavplfgslaclrrmvadegkiapdqvilteiyttgfqrsffddddl 382
           ******************99764.369************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 383  tiiaesdiiyafqasplyirggsarisgfhhslpsspysssgpeghrlaasgalsseflnqtdgmlkvlllvcnaagagqqavrfgppf 471
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 472  lmredrsvswdqlqqsilsklyylmingsqahnfrvlfkirvvggsasysylnpqdgrplfhpavdralklcgsggpphvklivewehr 560
           ***************************************************************************************** PP
   S: 186  .................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfse 241
                                            +l++c+e +tkee+l  +++++c++ck++q+ + +++l++lP++LilhLkRf  ++
   Q: 561  ikdclfgniqeevvkdsesvraqqqhhvqqhscTLDECFELYTKEEQLAPDDAWKCPHCKQLQQGTVQMSLWTLPDILILHLKRF--RQ 647
           *************************************************************************************..99 PP
   S: 242  eqksrekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllf 309
            +++r+k+++ v+fpl+ Ld+ ++++++++                       ++ Y+L+av++H+G++++GHY+ay++n  +g+W+++
   Q: 648  VGERRNKLSTLVHFPLTgLDMGRHMVQRTSCARAppgwnkqahrrpeasryatDVLYDLYAVCNHHGGMHGGHYTAYCRNsVDGQWYTY 736
           99***********************9955444446666666677777777777***************************55777**** PP
   S: 310  dDskVtevkeeevleetgstaYvlfYkrr 338
           dDs+V++++e ev++   + aY+lfY+rr
   Q: 737  DDSSVEPLQEGEVCT---RAAYILFYQRR 762
           ***************...*********96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDKRDKKANK DSGSKSTKRT GKLFRRKSFK SVESLVSRIL KSLGSLASGG ETAERSDAED 60
DDGGFGESAP CAGNSVKKED SSTSSSQVRK SSSLTSRSSA KERMFSLYGD KTPGVLGLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGGGTGTG ATTATTCGCA GCCACAACTG TCAATCATTG CATCGCTCGC AGATTCCCGC 60
CAGTATGAAG TTGGAGGAGC TCATGCTACC ACTGACCGCC GGTAAAAACG CGCTGTCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:100149276

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dme-032088	Drosophila melanogaster	36.61	1.00e-108	388.00
IUUC-Gmo-038903	Gadus morhua	60.49	0.00e+00	806.00
IUUC-Pfo-096332	Poecilia formosa	56.72	0.00e+00	1158.00
IUUC-Pva-102317	Pteropus vampyrus	49.21	0.00e+00	653.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence