iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027739

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like protein 41a; Kelch repeat and BTB domain-containing protein 10b

Genbank Nucleotide ID

BX321905

Gene Name

klhl41a; kbtbd10a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000068888.4	ENSDART00000099787.4	ENSDARP00000090560.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.00e-13	52.3	33	101
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.10e-07	30.2	135	165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalf..lmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+il+vg++  ++h++++aa+S++F+ l   + + e+++ +++v+++ v+p  +  ++++lY+  +d++
   Q: 33   DCILKVGDRSLPCHRLIMAACSPYFRELYftEDGTEKKDANKEVVLENVDPNIMDMIVNYLYSADIDIT 101
           9***************************87666667788889999999***************999976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Ncl+i+r++  ++cp+L+ +a+dfi  hF+
   Q: 135  GNCLAIFRMGLVLNCPRLAVSARDFIAEHFE 165
           5****************************95 PP

Organism

Danio rerio

Functional Description
(View)

Involved in skeletal muscle development and differentiation.

Protein Sequence
(Fasta)

MEPMSVKEDL RLFQSTLLQD GLKELLKENK FVDCILKVGD RSLPCHRLIM AACSPYFREL 60
YFTEDGTEKK DANKEVVLEN VDPNIMDMIV NYLYSADIDI TDDNVQDVFA VANKFQIPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAACCAA TGAGTGTCAA AGAGGACCTG AGGCTTTTTC AGAGCACCCT GCTTCAGGAT 60
GGCTTGAAGG AACTTCTGAA GGAGAACAAG TTTGTGGATT GCATACTGAA AGTTGGAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0256--Endoplasmic reticulum
KW-0880--Kelch repeat
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0703--Sarcoplasmic reticulum

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0031430--C:M band
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

dre:100148315

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011172	Astyanax mexicanus	80.63	0.00e+00	988.00
IUUC-Ete-032697	Echinops telfairi	59.07	0.00e+00	742.00
IUUC-Gmo-039392	Gadus morhua	70.62	0.00e+00	890.00
IUUC-Ola-087119	Oryzias latipes	72.62	0.00e+00	940.00
IUUC-Pfo-097135	Poecilia formosa	72.83	0.00e+00	941.00
IUUC-Pca-100495	Procavia capensis	55.91	0.00e+00	683.00
IUUC-Tru-117743	Takifugu rubripes	71.83	0.00e+00	895.00
IUUC-Tni-120328	Tetraodon nigroviridis	71.83	0.00e+00	884.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence