iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106695

Ensembl Protein ID

ENSSHAP00000000088.1

UniProt Accession

G3VA84; G3VA84_SARHA

Genbank Protein ID

ENSSHAP00000000088

Protein Name

Coronin

Genbank Nucleotide ID

AEFK01096987

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000000077.1	ENSSHAT00000000090.1	ENSSHAP00000000088.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-15	54.8	42	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 42   GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 74
           8***********977799*************86 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MFREGHIPNV FVFCLEDWLG TVIISVATCT GRIDKSYPTV CGHTGPVLDI DWCPHNDQVI 60
ASGSEDCTVM VWQIPENGLT LSLTEPVVIL EGHSKRVGIV AWHPTARNVL LSAGCDNAVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACTTGTAA TTGAATGAGT GCAGATATGC TCCTGACCTA CTGTCTGGCA ACTTTTAGAC 60
ATGGCTGGTC ACTGAAAATT GACCTTTCAT CCCCTTCATA TGAGCCACCA TGTTCCGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027333--CORO1C
IPR015505--Coronin
IPR002469--Peptidase_S9B_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	94.39	0.00e+00	806.00
IUUC-Apl-003861	Anas platyrhynchos	92.67	0.00e+00	794.00
IUUC-Bta-013225	Bos taurus	94.63	0.00e+00	804.00
IUUC-Cja-019948	Callithrix jacchus	94.16	0.00e+00	804.00
IUUC-Cfa-020591	Canis familiaris	94.63	0.00e+00	808.00
IUUC-Cpo-021480	Cavia porcellus	94.63	0.00e+00	808.00
IUUC-Csa-024152	Chlorocebus sabaeus	94.63	0.00e+00	809.00
IUUC-Cho-024687	Choloepus hoffmanni	95.36	0.00e+00	735.00
IUUC-Dno-029552	Dasypus novemcinctus	93.82	0.00e+00	735.00
IUUC-Dor-030188	Dipodomys ordii	81.95	0.00e+00	668.00
IUUC-Ete-032839	Echinops telfairi	84.88	0.00e+00	714.00
IUUC-Eca-034118	Equus caballus	94.15	0.00e+00	806.00
IUUC-Fca-035549	Felis catus	94.63	0.00e+00	807.00
IUUC-Fal-037065	Ficedula albicollis	92.42	0.00e+00	795.00
IUUC-Gga-040842	Gallus gallus	92.67	0.00e+00	798.00
IUUC-Ggo-044477	Gorilla gorilla	94.63	0.00e+00	807.00
IUUC-Hsa-046610	Homo sapiens	94.63	0.00e+00	807.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	94.39	0.00e+00	804.00
IUUC-Lch-050453	Latimeria chalumnae	83.17	0.00e+00	702.00
IUUC-Loc-052911	Lepisosteus oculatus	81.66	0.00e+00	699.00
IUUC-Laf-053416	Loxodonta africana	94.63	0.00e+00	808.00
IUUC-Mcc-055113	Macaca mulatta	94.63	0.00e+00	808.00
IUUC-Meu-056732	Macropus eugenii	88.05	0.00e+00	654.00
IUUC-Mga-060143	Meleagris gallopavo	92.67	0.00e+00	797.00
IUUC-Mmr-061130	Microcebus murinus	94.63	0.00e+00	808.00
IUUC-Mdo-062851	Monodelphis domestica	86.83	0.00e+00	683.00
IUUC-Mmu-063663	Mus musculus	93.41	0.00e+00	800.00
IUUC-Mpu-066179	Mustela putorius furo	94.63	0.00e+00	810.00
IUUC-Mlu-068175	Myotis lucifugus	95.12	0.00e+00	809.00
IUUC-Opr-070617	Ochotona princeps	93.66	0.00e+00	769.00
IUUC-Ont-072629	Oreochromis niloticus	79.71	0.00e+00	700.00
IUUC-Oan-073547	Ornithorhynchus anatinus	93.14	0.00e+00	793.00
IUUC-Ocu-074569	Oryctolagus cuniculus	93.17	0.00e+00	801.00
IUUC-Ola-086558	Oryzias latipes	77.22	0.00e+00	690.00
IUUC-Oga-089145	Otolemur garnettii	94.63	0.00e+00	809.00
IUUC-Oar-089654	Ovis aries	94.15	0.00e+00	804.00
IUUC-Ptr-090763	Pan troglodytes	94.63	0.00e+00	808.00
IUUC-Pan-091885	Papio anubis	94.40	0.00e+00	804.00
IUUC-Psi-093011	Pelodiscus sinensis	92.42	0.00e+00	791.00
IUUC-Pfo-097309	Poecilia formosa	79.95	0.00e+00	711.00
IUUC-Pab-097542	Pongo abelii	84.88	0.00e+00	705.00
IUUC-Pca-100630	Procavia capensis	82.14	0.00e+00	704.00
IUUC-Rno-105330	Rattus norvegicus	93.90	0.00e+00	806.00
IUUC-Ssc-115348	Sus scrofa	94.15	0.00e+00	804.00
IUUC-Tgu-116597	Taeniopygia guttata	92.91	0.00e+00	795.00
IUUC-Tsy-119223	Tarsius syrichta	94.77	0.00e+00	648.00
IUUC-Tni-120435	Tetraodon nigroviridis	74.94	0.00e+00	687.00
IUUC-Ttr-129226	Tursiops truncatus	82.79	0.00e+00	673.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence