iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091463

Ensembl Protein ID

ENSPTRP00000014539.3

UniProt Accession

H2QBT8; H2QBT8_PANTR

Genbank Protein ID

ENSPTRP00000014539

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03112433

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000008522.3	ENSPTRT00000015716.3	ENSPTRP00000014539.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-18	66.7	122	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 122  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 177
           689*************************..6999******9.5**************98 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVALLQGQ SPGDYVLSVS ENWGVSHYII NSSGPRPPVP 60
PSPAQPPPGV SPSRLRIGDQ EFDSLPALLE FYKIHYLDTT TLIEPVSRSR QGSGVILRQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCA ACTTCGACTC GGAGGAGCGG AGTAGCTGGT ACTGGGGGCG GTTGAGTCGG 60
CAGGAGGCGG TGGCGCTGCT GCAGGGCCAG NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	94.98	2.00e-148	517.00
IUUC-Apl-003225	Anas platyrhynchos	92.00	2.00e-122	431.00
IUUC-Aca-004818	Anolis carolinensis	78.35	7.00e-93	332.00
IUUC-Ame-011721	Astyanax mexicanus	64.56	4.00e-108	384.00
IUUC-Bta-012320	Bos taurus	95.39	1.00e-151	528.00
IUUC-Cja-019935	Callithrix jacchus	91.78	7.00e-156	542.00
IUUC-Cfa-021221	Canis familiaris	95.07	2.00e-151	528.00
IUUC-Cpo-021592	Cavia porcellus	87.03	2.00e-136	478.00
IUUC-Csa-024128	Chlorocebus sabaeus	93.10	6.00e-89	319.00
IUUC-Cho-024775	Choloepus hoffmanni	93.42	3.00e-150	523.00
IUUC-Dre-027390	Danio rerio	65.53	2.00e-109	388.00
IUUC-Dno-029847	Dasypus novemcinctus	95.39	1.00e-151	528.00
IUUC-Dor-030360	Dipodomys ordii	85.86	4.00e-146	509.00
IUUC-Ete-032604	Echinops telfairi	96.86	5.00e-126	442.00
IUUC-Eca-033233	Equus caballus	93.73	5.00e-152	529.00
IUUC-Eeu-034642	Erinaceus europaeus	97.31	9.00e-128	448.00
IUUC-Fca-035955	Felis catus	99.56	4.00e-131	459.00
IUUC-Fal-037152	Ficedula albicollis	86.79	1.00e-131	462.00
IUUC-Gmo-038849	Gadus morhua	63.92	3.00e-107	380.00
IUUC-Gga-040861	Gallus gallus	80.33	4.00e-140	490.00
IUUC-Gac-041627	Gasterosteus aculeatus	62.93	9.00e-110	389.00
IUUC-Ggo-045475	Gorilla gorilla	95.39	1.00e-151	528.00
IUUC-Hsa-046008	Homo sapiens	95.39	1.00e-151	528.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	94.25	3.00e-122	430.00
IUUC-Lch-050509	Latimeria chalumnae	77.42	3.00e-137	481.00
IUUC-Loc-052229	Lepisosteus oculatus	69.12	1.00e-97	348.00
IUUC-Laf-053896	Loxodonta africana	90.55	6.00e-155	539.00
IUUC-Mcc-055280	Macaca mulatta	95.39	1.00e-151	528.00
IUUC-Meu-056783	Macropus eugenii	96.86	1.00e-126	444.00
IUUC-Mga-059345	Meleagris gallopavo	92.38	1.00e-123	434.00
IUUC-Mdo-062691	Monodelphis domestica	84.09	3.00e-142	497.00
IUUC-Mmu-063691	Mus musculus	95.07	2.00e-151	527.00
IUUC-Mpu-065737	Mustela putorius furo	95.07	1.00e-151	528.00
IUUC-Mlu-067005	Myotis lucifugus	92.11	7.00e-147	512.00
IUUC-Nle-070154	Nomascus leucogenys	99.56	8.00e-131	459.00
IUUC-Opr-071114	Ochotona princeps	93.75	1.00e-154	538.00
IUUC-Ont-071696	Oreochromis niloticus	65.92	6.00e-105	373.00
IUUC-Oan-072967	Ornithorhynchus anatinus	88.08	5.00e-121	426.00
IUUC-Ocu-074025	Oryctolagus cuniculus	92.12	1.00e-87	315.00
IUUC-Ola-087265	Oryzias latipes	63.48	7.00e-85	306.00
IUUC-Oga-088266	Otolemur garnettii	94.08	1.00e-150	525.00
IUUC-Oar-089221	Ovis aries	94.10	1.00e-147	515.00
IUUC-Pan-092242	Papio anubis	95.07	1.00e-151	528.00
IUUC-Psi-093287	Pelodiscus sinensis	94.64	1.00e-126	444.00
IUUC-Pfo-097378	Poecilia formosa	62.38	2.00e-99	355.00
IUUC-Pab-097823	Pongo abelii	93.10	6.00e-89	319.00
IUUC-Pca-101068	Procavia capensis	95.39	1.00e-151	528.00
IUUC-Rno-105288	Rattus norvegicus	95.07	3.00e-151	527.00
IUUC-Sar-113453	Sorex araneus	81.25	4.00e-138	483.00
IUUC-Tgu-116926	Taeniopygia guttata	82.62	3.00e-139	487.00
IUUC-Tru-118656	Takifugu rubripes	63.53	4.00e-110	390.00
IUUC-Tni-120497	Tetraodon nigroviridis	64.33	3.00e-104	370.00
IUUC-Tbe-127436	Tupaia belangeri	90.46	7.00e-133	466.00
IUUC-Ttr-129109	Tursiops truncatus	100.00	3.00e-130	456.00
IUUC-Vpa-130527	Vicugna pacos	95.07	1.00e-149	521.00
IUUC-Xtr-131808	Xenopus tropicalis	80.66	4.00e-139	487.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence