iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Smo-108986

Ensembl Protein ID

EFJ37162

UniProt Accession

D8QTS3; D8QTS3_SELML

Genbank Protein ID

EFJ37162.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

GL377566

Gene Name

SELMODRAFT_77651

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_77651	EFJ37162	EFJ37162

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-39	132.8	50	86
UBD/Beta-Prp	1.20e-78	265.1	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f s+ +l+vsG+dD +ikvW+++  ++l
   Q: 50   HDGPVRGIHFhSSqPLFVSGGDDYKIKVWNYKARRCL 86
           99*********767****************9887776 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+p++++++++  +g i +wd+++g+l+ ++ +h+++v+ + f+++++++v+g++D+ ikvw+++++ c+ tl gh d++++++f++
   Q: 3    TTFETKSNRVKGLSFHPKRPWILASLHTGVIHLWDYRMGSLIDRFDEHDGPVRGIHFHSSQPLFVSGGDDYKIKVWNYKARRCLFTLLGHLDYIRTVQFHQ 103
           77889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........................ktgkllrtl.tggh 179
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++h +++l+vs+slD+tvr+Wd+                           g+++ +   +gh
   Q: 104  EYPWIVSASDDQTIRIWNWQSRTCVS-VLTGHNHYVMCASFHVKDDLVVSASLDQTVRVWDIsslrkktvspaedllmltqmnsdlfGGGDVVVKYvLEGH 203
           **************************.****************************************999999999988888777774444444436555* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
           ++ v++ +f+++ + +vsg++d++vklw +  ++   v+tl+ght+nv++v f+ +++++vs s+D++ir+Wdl ++  ++t+ + +++++ +++ +++ n
   Q: 204  DRGVNWAAFHPSLPLIVSGADDRQVKLWRINDTKAweVDTLRGHTNNVSCVLFHARQDIIVSNSEDKTIRVWDLSKRSAVQTFRRDHDRFWVICG-HPEMN 303
           *******************************777668*********************************************************9.66666 PP
   S: 279  vlvlgsedskvniwklkknep 299
            l++g  ds + ++kl++++p
   Q: 304  LLAAG-HDSGIIVFKLERERP 323
           55554.689999***998775 PP

Organism

Selaginella moellendorffii

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTTFETKSN RVKGLSFHPK RPWILASLHT GVIHLWDYRM GSLIDRFDEH DGPVRGIHFH 60
SSQPLFVSGG DDYKIKVWNY KARRCLFTLL GHLDYIRTVQ FHQEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACGA CGTTCGAGAC GAAGAGCAAT CGCGTCAAGG GCCTGAGCTT CCATCCCAAG 60
CGGCCATGGA TCTTGGCCAG TCTCCACACC GGCGTCATTC ATCTGTGGGA TTACCGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

smo:SELMODRAFT_77651

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Lpe-051316	Leersia perrieri	66.48	0.00e+00	1674.00
IUUC-Opr-070952	Ochotona princeps	44.30	0.00e+00	847.00
IUUC-Pfo-097493	Poecilia formosa	54.10	0.00e+00	1314.00
IUUC-Sar-113313	Sorex araneus	39.98	2.00e-179	622.00
IUUC-Sbi-114388	Sorghum bicolor	65.27	0.00e+00	1684.00
IUUC-Tbe-127882	Tupaia belangeri	51.31	6.00e-157	547.00
IUUC-Vvi-130958	Vitis vinifera	66.97	0.00e+00	1716.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence