iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053950

UUCD1 version

UUC-LoA-00767

Ensembl Protein ID

ENSLAFP00000021212.1

UniProt Accession

G3U054; G3U054_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000012480.3	ENSLAFT00000012478.3	ENSLAFP00000010428.3
ENSLAFG00000012480.3	ENSLAFT00000030834.1	ENSLAFP00000021212.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-41	139.4	508	540
UBD/Beta-Prp	1.70e-66	224.8	271	564

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++sGs D++++vWD+r
   Q: 508  GHTDNITSLTFsPDsSLIASGSMDNSVRVWDIR 540
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g++++++k+w+++++kl                                ++ l gh ++v+  +f ++++ l++
   Q: 271  LNTAEISPDSKLLAAGFDNSCVKLWSLRSKKLksephqvdvsrihlacdileeexxxxxxxxxeMKILRGHCGPVYRARFCQTAPGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGs drt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSYDRTARLWSFDRTYPLR-IYAGHLADVDCVRFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++sgs+D+s+r
   Q: 448  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASGSMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvavlsfg 276
           +Wd+r+  +     ++ s ++ v + +++
   Q: 536  VWDIRNTYCSAPADGSSSELVGVYTGQMS 564
           **999999988888888666666663333 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MKRVRTEQIQ TAVSCYLKRR QYADSEGLLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGAG TGCGCACAGA GCAGATTCAG ACGGCAGTGT CCTGCTACCT CAAACGCCGA 60
CAGTACGCGG ATTCAGAAGG TCTCCTAAAA CAAGGATTGC GACTGTCACA GACTGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	93.89	0.00e+00	1068.00
IUUC-Apl-003636	Anas platyrhynchos	89.17	0.00e+00	1058.00
IUUC-Aca-004229	Anolis carolinensis	88.79	0.00e+00	1034.00
IUUC-Ame-010599	Astyanax mexicanus	65.07	0.00e+00	791.00
IUUC-Bta-013404	Bos taurus	89.30	0.00e+00	1019.00
IUUC-Cja-019643	Callithrix jacchus	93.55	0.00e+00	1071.00
IUUC-Cfa-020913	Canis familiaris	93.55	0.00e+00	1068.00
IUUC-Cpo-021777	Cavia porcellus	90.66	0.00e+00	1035.00
IUUC-Csa-024184	Chlorocebus sabaeus	93.55	0.00e+00	1076.00
IUUC-Cho-024638	Choloepus hoffmanni	94.23	0.00e+00	1070.00
IUUC-Cin-025618	Ciona intestinalis	35.69	8.00e-90	324.00
IUUC-Csv-025874	Ciona savignyi	33.96	7.00e-85	308.00
IUUC-Dre-028817	Danio rerio	65.45	0.00e+00	774.00
IUUC-Dno-029969	Dasypus novemcinctus	85.74	0.00e+00	995.00
IUUC-Dor-031117	Dipodomys ordii	91.17	0.00e+00	1070.00
IUUC-Ete-032712	Echinops telfairi	87.10	0.00e+00	967.00
IUUC-Eca-033742	Equus caballus	93.55	0.00e+00	1069.00
IUUC-Eeu-035096	Erinaceus europaeus	91.36	0.00e+00	1080.00
IUUC-Fca-035769	Felis catus	92.55	0.00e+00	1086.00
IUUC-Fal-036645	Ficedula albicollis	88.67	0.00e+00	993.00
IUUC-Fso-038302	Fusarium solani	34.42	1.00e-41	164.00
IUUC-Gmo-038636	Gadus morhua	63.00	0.00e+00	748.00
IUUC-Gga-040144	Gallus gallus	88.96	0.00e+00	1026.00
IUUC-Gac-041716	Gasterosteus aculeatus	66.72	0.00e+00	786.00
IUUC-Ggo-044568	Gorilla gorilla	93.72	0.00e+00	1072.00
IUUC-Hsa-046178	Homo sapiens	93.72	0.00e+00	1072.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	86.59	0.00e+00	1032.00
IUUC-Lch-050501	Latimeria chalumnae	75.53	0.00e+00	827.00
IUUC-Loc-052895	Lepisosteus oculatus	80.11	0.00e+00	629.00
IUUC-Mcc-055450	Macaca mulatta	93.55	0.00e+00	1068.00
IUUC-Meu-056182	Macropus eugenii	85.91	0.00e+00	969.00
IUUC-Mga-059619	Meleagris gallopavo	89.13	0.00e+00	1029.00
IUUC-Mmr-061074	Microcebus murinus	92.55	0.00e+00	1061.00
IUUC-Mdo-062307	Monodelphis domestica	90.42	0.00e+00	847.00
IUUC-Mmu-063226	Mus musculus	89.13	0.00e+00	1017.00
IUUC-Mpu-066016	Mustela putorius furo	93.38	0.00e+00	1062.00
IUUC-Mlu-067257	Myotis lucifugus	85.98	0.00e+00	1036.00
IUUC-Nle-070139	Nomascus leucogenys	93.55	0.00e+00	1070.00
IUUC-Opr-070243	Ochotona princeps	88.62	0.00e+00	1027.00
IUUC-Ont-072686	Oreochromis niloticus	66.33	0.00e+00	802.00
IUUC-Oan-073670	Ornithorhynchus anatinus	81.49	0.00e+00	798.00
IUUC-Ocu-074525	Oryctolagus cuniculus	92.87	0.00e+00	1068.00
IUUC-Ola-086524	Oryzias latipes	66.39	0.00e+00	823.00
IUUC-Oga-088540	Otolemur garnettii	93.04	0.00e+00	1058.00
IUUC-Oar-089793	Ovis aries	86.08	0.00e+00	952.00
IUUC-Ptr-091154	Pan troglodytes	93.72	0.00e+00	1072.00
IUUC-Pan-092759	Papio anubis	93.55	0.00e+00	1068.00
IUUC-Psi-094008	Pelodiscus sinensis	86.59	0.00e+00	1024.00
IUUC-Pma-094593	Petromyzon marinus	46.52	3.00e-130	458.00
IUUC-Pfo-097409	Poecilia formosa	65.39	0.00e+00	784.00
IUUC-Pab-097946	Pongo abelii	80.98	0.00e+00	899.00
IUUC-Pca-100727	Procavia capensis	88.62	0.00e+00	987.00
IUUC-Pva-103211	Pteropus vampyrus	81.83	0.00e+00	966.00
IUUC-Rno-105236	Rattus norvegicus	89.64	0.00e+00	1014.00
IUUC-Sha-106833	Sarcophilus harrisii	90.88	0.00e+00	1043.00
IUUC-Sar-113381	Sorex araneus	93.38	0.00e+00	1098.00
IUUC-Ssc-116421	Sus scrofa	91.51	0.00e+00	1084.00
IUUC-Tgu-117143	Taeniopygia guttata	89.47	0.00e+00	1061.00
IUUC-Tru-118680	Takifugu rubripes	65.67	0.00e+00	803.00
IUUC-Tsy-119622	Tarsius syrichta	78.61	0.00e+00	832.00
IUUC-Tni-120131	Tetraodon nigroviridis	65.33	0.00e+00	804.00
IUUC-Tbe-127656	Tupaia belangeri	88.14	9.00e-81	294.00
IUUC-Ttr-129171	Tursiops truncatus	90.32	0.00e+00	1039.00
IUUC-Xtr-132241	Xenopus tropicalis	78.81	0.00e+00	917.00
IUUC-Xma-133554	Xiphophorus maculatus	65.61	0.00e+00	724.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence