iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005129

Ensembl Protein ID

ENSACAP00000013155.3

UniProt Accession

G1KNP4; G1KNP4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PPARG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000013360.3	ENSACAT00000013417.3	ENSACAP00000013155.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.75	0.00e+00	876.00	IUUC-Hsa-046916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MLISHFKPSF RARWFFRNPM EVCATISAGT TAKELGFTMV DTEMPFWPMN FGISPVDLSA 60
MDEHSHSFDI KPFTTVDFSS LSSPHYEDLA LARTDQMAID YKYDVKFQEC QNTIKLEPPS 120

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Nucleotide Sequence
(Fasta)

TGTTCAGGGA AGACTACAAT AAAAAATATC TGTAATTCAT AATGATACAT GTTCAAAATA 60
TTAAAGTAGC TTCTTGATCA CAATTGATAG CCTTTTTGCT CTTTTAGTGC TGATCTCTAG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003077--1Cnucl_rcpt_G
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR022590--PPARgamma_N
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF12577--PPARgamma_N
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01291--PROXISOMPAGR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0090575--C:RNA polymerase II transcription factor complex
GO:0008144--F:drug binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048469--P:cell maturation
GO:0032869--P:cellular response to insulin stimulus
GO:0042593--P:glucose homeostasis
GO:0042953--P:lipoprotein transport
GO:0045713--P:low-density lipoprotein particle receptor biosynthetic process
GO:0010742--P:macrophage derived foam cell differentiation
GO:0030224--P:monocyte differentiation
GO:0010887--P:negative regulation of cholesterol storage
GO:0060336--P:negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035357--P:peroxisome proliferator activated receptor signaling pathway
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008217--P:regulation of blood pressure
GO:0055098--P:response to low-density lipoprotein particle
GO:0032526--P:response to retinoic acid
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001214	Ailuropoda melanoleuca	88.80	0.00e+00	876.00
IUUC-Ame-010818	Astyanax mexicanus	64.97	0.00e+00	633.00
IUUC-Bta-013226	Bos taurus	87.98	0.00e+00	871.00
IUUC-Cja-019236	Callithrix jacchus	88.96	0.00e+00	878.00
IUUC-Cfa-020281	Canis familiaris	89.16	0.00e+00	880.00
IUUC-Cpo-021587	Cavia porcellus	89.08	0.00e+00	861.00
IUUC-Csa-023400	Chlorocebus sabaeus	90.74	0.00e+00	874.00
IUUC-Cho-024593	Choloepus hoffmanni	78.57	0.00e+00	758.00
IUUC-Cgl-026609	Colletotrichum gloeosporioides	32.50	5.50e-01	28.50
IUUC-Dre-028176	Danio rerio	59.95	3.00e-153	534.00
IUUC-Dno-029063	Dasypus novemcinctus	91.00	0.00e+00	880.00
IUUC-Ete-032520	Echinops telfairi	87.53	0.00e+00	855.00
IUUC-Fca-035935	Felis catus	89.37	0.00e+00	880.00
IUUC-Fal-037524	Ficedula albicollis	93.47	0.00e+00	905.00
IUUC-Gga-041223	Gallus gallus	93.68	0.00e+00	905.00
IUUC-Gac-042156	Gasterosteus aculeatus	61.67	0.00e+00	630.00
IUUC-Ggo-045265	Gorilla gorilla	88.96	0.00e+00	878.00
IUUC-Hsa-046916	Homo sapiens	88.75	0.00e+00	877.00
IUUC-Lch-049759	Latimeria chalumnae	79.55	0.00e+00	672.00
IUUC-Loc-051870	Lepisosteus oculatus	74.38	0.00e+00	751.00
IUUC-Laf-054483	Loxodonta africana	87.73	0.00e+00	866.00
IUUC-Meu-056587	Macropus eugenii	89.96	0.00e+00	848.00
IUUC-Mga-059530	Meleagris gallopavo	93.68	0.00e+00	905.00
IUUC-Mmr-060576	Microcebus murinus	88.11	0.00e+00	866.00
IUUC-Mdo-061854	Monodelphis domestica	90.74	0.00e+00	877.00
IUUC-Mmu-063724	Mus musculus	88.43	0.00e+00	870.00
IUUC-Mpu-066888	Mustela putorius furo	90.53	0.00e+00	904.00
IUUC-Mlu-067978	Myotis lucifugus	88.59	0.00e+00	912.00
IUUC-Nle-070069	Nomascus leucogenys	89.16	0.00e+00	879.00
IUUC-Opr-070630	Ochotona princeps	85.82	0.00e+00	707.00
IUUC-Ont-071399	Oreochromis niloticus	59.02	3.00e-180	624.00
IUUC-Ocu-074862	Oryctolagus cuniculus	90.74	0.00e+00	874.00
IUUC-Ola-087266	Oryzias latipes	55.68	3.00e-157	548.00
IUUC-Oga-089143	Otolemur garnettii	88.34	0.00e+00	870.00
IUUC-Oar-089725	Ovis aries	87.98	0.00e+00	871.00
IUUC-Ptr-091580	Pan troglodytes	88.96	0.00e+00	878.00
IUUC-Psi-093041	Pelodiscus sinensis	91.21	0.00e+00	878.00
IUUC-Pfo-097438	Poecilia formosa	58.91	2.00e-178	618.00
IUUC-Pab-098333	Pongo abelii	90.13	0.00e+00	863.00
IUUC-Pca-100861	Procavia capensis	89.71	0.00e+00	865.00
IUUC-Pva-102186	Pteropus vampyrus	78.73	0.00e+00	756.00
IUUC-Rno-105583	Rattus norvegicus	88.64	0.00e+00	870.00
IUUC-Sha-107484	Sarcophilus harrisii	90.38	0.00e+00	879.00
IUUC-Sar-112996	Sorex araneus	80.05	2.00e-176	611.00
IUUC-Ssc-115945	Sus scrofa	88.55	0.00e+00	872.00
IUUC-Tsy-119098	Tarsius syrichta	79.35	0.00e+00	756.00
IUUC-Tni-120902	Tetraodon nigroviridis	61.22	1.00e-171	595.00
IUUC-Tbe-127225	Tupaia belangeri	67.48	8.00e-177	613.00
IUUC-Ttr-129292	Tursiops truncatus	88.55	0.00e+00	874.00
IUUC-Vpa-130378	Vicugna pacos	83.95	0.00e+00	691.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence