iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035616

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02087782

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015479.3	ENSFCAT00000015483.3	ENSFCAP00000014353.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-14	53.1	1126	1159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t +   d t+ l+sG+ Dg i +WD+ tg
   Q: 1126 GHSGAITTVYI-DqTMvLASGGQDGAICLWDVLTG 1159
           8********88.446648*************9887 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MTLTERLREK ISQAFYNHGL LCASYPIPII LFTGLCILAC CCPLLKLPLP GTGPVEFTTP 60
VKDYSPPPVA SDHKPGEPSE RPEWYVGAPV AYIQQIFVKS SVSPWHKNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCCCTTGC CAGGTATCTG CACATGGTGT CCATTGTCAG CGCTGTCCAG CGTGCACCAG 60
GCTGATCCAT GGTCACTTTC CGGGATGGCA GCAAGGTGAC TTCAGCTGAG GATGACCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	85.97	0.00e+00	1132.00
IUUC-Apl-003294	Anas platyrhynchos	73.50	0.00e+00	1636.00
IUUC-Aca-004424	Anolis carolinensis	66.56	0.00e+00	1439.00
IUUC-Bta-013478	Bos taurus	87.83	0.00e+00	1964.00
IUUC-Cel-018160	Caenorhabditis elegans	30.29	4.00e-66	246.00
IUUC-Cja-019123	Callithrix jacchus	84.67	0.00e+00	1894.00
IUUC-Cfa-021082	Canis familiaris	97.56	0.00e+00	1135.00
IUUC-Cpo-022477	Cavia porcellus	80.02	0.00e+00	1809.00
IUUC-Csa-023176	Chlorocebus sabaeus	84.70	0.00e+00	1879.00
IUUC-Cin-025490	Ciona intestinalis	42.24	2.00e-78	287.00
IUUC-Csv-026115	Ciona savignyi	39.61	3.00e-120	426.00
IUUC-Dre-028008	Danio rerio	71.56	0.00e+00	872.00
IUUC-Dno-028887	Dasypus novemcinctus	91.46	0.00e+00	1117.00
IUUC-Dor-030467	Dipodomys ordii	93.67	0.00e+00	881.00
IUUC-Dme-032087	Drosophila melanogaster	32.97	7.00e-95	342.00
IUUC-Ete-032372	Echinops telfairi	73.39	0.00e+00	1603.00
IUUC-Eca-033896	Equus caballus	95.27	0.00e+00	1141.00
IUUC-Eeu-035099	Erinaceus europaeus	77.35	0.00e+00	1089.00
IUUC-Fal-037231	Ficedula albicollis	80.33	0.00e+00	933.00
IUUC-Gmo-039439	Gadus morhua	65.51	0.00e+00	734.00
IUUC-Gac-041516	Gasterosteus aculeatus	70.61	0.00e+00	830.00
IUUC-Hsa-046674	Homo sapiens	86.06	0.00e+00	2019.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	94.82	0.00e+00	1157.00
IUUC-Lch-049689	Latimeria chalumnae	67.38	0.00e+00	1564.00
IUUC-Loc-052417	Lepisosteus oculatus	50.84	3.00e-82	299.00
IUUC-Laf-053795	Loxodonta africana	86.58	0.00e+00	1973.00
IUUC-Mcc-055502	Macaca mulatta	87.58	0.00e+00	1996.00
IUUC-Mga-059805	Meleagris gallopavo	74.32	0.00e+00	1663.00
IUUC-Mmr-060997	Microcebus murinus	86.31	0.00e+00	2022.00
IUUC-Mdo-062940	Monodelphis domestica	77.91	0.00e+00	1753.00
IUUC-Mmu-063255	Mus musculus	93.75	0.00e+00	1143.00
IUUC-Mpu-066158	Mustela putorius furo	88.01	0.00e+00	2026.00
IUUC-Mlu-067201	Myotis lucifugus	88.47	0.00e+00	1054.00
IUUC-Nle-069145	Nomascus leucogenys	94.33	0.00e+00	1140.00
IUUC-Opr-070797	Ochotona princeps	84.15	0.00e+00	950.00
IUUC-Ont-071553	Oreochromis niloticus	72.57	0.00e+00	862.00
IUUC-Ocu-074598	Oryctolagus cuniculus	86.84	0.00e+00	1944.00
IUUC-Ola-086650	Oryzias latipes	84.23	1.00e-112	398.00
IUUC-Oar-089287	Ovis aries	81.43	0.00e+00	1015.00
IUUC-Pan-092004	Papio anubis	87.40	0.00e+00	1967.00
IUUC-Psi-093028	Pelodiscus sinensis	80.41	0.00e+00	992.00
IUUC-Pma-094145	Petromyzon marinus	61.65	0.00e+00	750.00
IUUC-Pfo-096320	Poecilia formosa	70.41	0.00e+00	845.00
IUUC-Pab-097862	Pongo abelii	87.58	0.00e+00	2019.00
IUUC-Pca-100862	Procavia capensis	74.37	0.00e+00	1560.00
IUUC-Pva-103050	Pteropus vampyrus	82.58	0.00e+00	1230.00
IUUC-Rno-105852	Rattus norvegicus	93.90	0.00e+00	1144.00
IUUC-Sha-107312	Sarcophilus harrisii	85.56	0.00e+00	1042.00
IUUC-Sar-113311	Sorex araneus	89.26	0.00e+00	834.00
IUUC-Ssc-116356	Sus scrofa	87.97	0.00e+00	2037.00
IUUC-Tgu-116896	Taeniopygia guttata	62.71	4.00e-95	342.00
IUUC-Tru-118197	Takifugu rubripes	72.16	0.00e+00	851.00
IUUC-Tni-119823	Tetraodon nigroviridis	68.93	0.00e+00	842.00
IUUC-Ttr-129164	Tursiops truncatus	87.75	0.00e+00	1958.00
IUUC-Xtr-132819	Xenopus tropicalis	66.54	0.00e+00	1554.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence