iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020663

Ensembl Protein ID

ENSCAFP00000038353.1

UniProt Accession

J9NYI4; J9NYI4_CANLF

Genbank Protein ID

ENSCAFP00000038353

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAEX03016430

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000007974.1	ENSCAFT00000012736.1	ENSCAFP00000038353.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.90e-09	36.3	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MLSPVNGEQM HLVNYAEDYL DSIESLPLDL QRNVSLMREI DTKYQEILKE LDEYYEKFKR 60
ETDSVQKRRV LHCIQRALIR SQELGDGKIQ IVSQMVELVE NRTRQVDSHV ELFEAHQEVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGCC CTGTCAATGG GGAGCAGATG CACCTGGTGA ACTATGCGGA GGACTACCTG 60
GACTCCATCG AGTCTCTGCC TTTGGACCTG CAGAGAAACG TCTCCCTGAT GCGGGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cne-027005	Cryptococcus neoformans	45.95	2.00e-16	79.70
IUUC-Dor-030315	Dipodomys ordii	88.89	5.00e-109	387.00
IUUC-Gac-041996	Gasterosteus aculeatus	63.12	2.00e-94	338.00
IUUC-Mlu-067586	Myotis lucifugus	82.21	1.00e-122	432.00
IUUC-Ola-086891	Oryzias latipes	65.00	4.00e-95	340.00
IUUC-Pfo-097531	Poecilia formosa	60.39	6.00e-92	330.00
IUUC-Tni-119980	Tetraodon nigroviridis	61.07	6.00e-84	303.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	91.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence