iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116187

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU582807

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000009885.2	ENSSSCT00000010835.2	ENSSSCP00000010552.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.60e-79	268.0	2551	2911

Active Site

Position(s)	Description	Evidence
2885	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq+++l+l+       ++++++k+ l+p+p ++     +++l +flG+llg+a++
   Q: 2551 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSSLSLLllcpssaVNKNKGKYILTPSPITY----GEEQLLHFLGQLLGIAIR 2633
           5667788*********************************9999999888888***********9....789*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelykslkeik.enaesdieelgldltfs..vseei...............lget 151
            + +l+l+l +sf+k+l+g++l+  +dl+e d  +y+++k+ +  n+e ++e+l+++++++  +  ++                 + 
   Q: 2634 ADVPLPLDLLPSFWKTLVGEPLDPdQDLQEADILTYNYVKKFEsINDEIELEALCAEIASQhlA--TEspdgpnkpccrftylTMTG 2718
           **************************************66666155555777777777777432..335799*********655555 PP
   S: 152  keeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykg 237
           +e+eL+++G++ipV++eNk+ Y   + ++rl+e +  e+v+a+r+G+ ++ipl+ll+ +++ e+el +cG ++i++e lk++t+y+ 
   Q: 2719 EEVELCSRGRHIPVAWENKDIYAATIRSLRLRElQNVECVTAVRAGLGSIIPLQLLTTLSPLEMELRTCGLPYINLEFLKAHTMYQV 2805
           6667*****************************9***************************************************** PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLP 311
           g++e++++i++Fw +le+f +ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP
   Q: 2806 GLMETDQHIEFFWGALEMFAQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgtaGSPDSRYIRVETCMFMIKLP 2892
           *********************************************99999999988888888889955555**************** PP
   S: 312  eYsskeilkekLlyAieet 330
           +Yss ei+ ekL++Ai+++
   Q: 2893 QYSSLEIMLEKLRCAIHYR 2911
           ****************986 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

PACKSASETK VISHAVRQPV FLRSMSAPSD LEMIGNEDLE FTRANQRRRH VTSHRSSSFT 60
LLQSLAIEDS RDKPTYSVLL GQLFAFIGTN PDQAVSSSSF LLAAQTRWRR GNTRKQALVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCTTGTA AATCAGCCTC TGAAACAAAG GTGATATCTC ATGCCGTGCG GCAGCCTGTT 60
TTTCTTCGTA GCATGTCAGC TCCTTCTGAC CTGGAAATGA TTGGTAATGA AGATTTGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	98.25	0.00e+00	5182.00
IUUC-Apl-004161	Anas platyrhynchos	92.67	0.00e+00	5021.00
IUUC-Aca-005341	Anolis carolinensis	91.38	0.00e+00	4903.00
IUUC-Ame-011574	Astyanax mexicanus	85.32	0.00e+00	2925.00
IUUC-Bta-012514	Bos taurus	98.36	0.00e+00	1961.00
IUUC-Cja-019148	Callithrix jacchus	96.92	0.00e+00	5115.00
IUUC-Cfa-020499	Canis familiaris	98.25	0.00e+00	5173.00
IUUC-Cpo-021894	Cavia porcellus	97.44	0.00e+00	2612.00
IUUC-Csa-023079	Chlorocebus sabaeus	97.87	0.00e+00	5185.00
IUUC-Cho-024415	Choloepus hoffmanni	94.78	0.00e+00	3145.00
IUUC-Dre-027452	Danio rerio	83.48	0.00e+00	2939.00
IUUC-Dno-029595	Dasypus novemcinctus	97.16	0.00e+00	5192.00
IUUC-Dor-030849	Dipodomys ordii	94.35	0.00e+00	1541.00
IUUC-Ete-032563	Echinops telfairi	90.70	0.00e+00	1613.00
IUUC-Eca-034202	Equus caballus	98.18	0.00e+00	5095.00
IUUC-Eeu-035175	Erinaceus europaeus	97.47	0.00e+00	1083.00
IUUC-Fca-036295	Felis catus	97.91	0.00e+00	5197.00
IUUC-Fal-037003	Ficedula albicollis	92.70	0.00e+00	4215.00
IUUC-Gmo-038579	Gadus morhua	85.86	0.00e+00	2763.00
IUUC-Gga-040961	Gallus gallus	92.77	0.00e+00	4998.00
IUUC-Gac-041899	Gasterosteus aculeatus	85.85	0.00e+00	2810.00
IUUC-Ggo-045099	Gorilla gorilla	98.01	0.00e+00	5266.00
IUUC-Hsa-046331	Homo sapiens	98.01	0.00e+00	5240.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	96.92	0.00e+00	2155.00
IUUC-Lch-049923	Latimeria chalumnae	92.23	0.00e+00	1016.00
IUUC-Loc-052630	Lepisosteus oculatus	84.31	0.00e+00	4039.00
IUUC-Laf-053394	Loxodonta africana	97.46	0.00e+00	5244.00
IUUC-Mcc-055763	Macaca mulatta	97.91	0.00e+00	5182.00
IUUC-Meu-056039	Macropus eugenii	89.07	0.00e+00	4722.00
IUUC-Mga-059500	Meleagris gallopavo	92.54	0.00e+00	4977.00
IUUC-Mmr-060868	Microcebus murinus	92.71	0.00e+00	4906.00
IUUC-Mdo-062772	Monodelphis domestica	93.76	0.00e+00	5061.00
IUUC-Mmu-063606	Mus musculus	96.64	0.00e+00	5160.00
IUUC-Mpu-065860	Mustela putorius furo	96.61	0.00e+00	5109.00
IUUC-Mlu-067376	Myotis lucifugus	98.08	0.00e+00	3315.00
IUUC-Nle-069693	Nomascus leucogenys	96.03	0.00e+00	5110.00
IUUC-Ont-072470	Oreochromis niloticus	85.11	0.00e+00	2957.00
IUUC-Oan-073693	Ornithorhynchus anatinus	92.57	0.00e+00	5049.00
IUUC-Ocu-074032	Oryctolagus cuniculus	96.37	0.00e+00	5137.00
IUUC-Ola-087433	Oryzias latipes	85.40	0.00e+00	1340.00
IUUC-Oga-088546	Otolemur garnettii	97.87	0.00e+00	5192.00
IUUC-Oar-089643	Ovis aries	91.89	0.00e+00	766.00
IUUC-Ptr-090504	Pan troglodytes	98.05	0.00e+00	5244.00
IUUC-Pan-092543	Papio anubis	97.87	0.00e+00	5189.00
IUUC-Psi-093952	Pelodiscus sinensis	89.80	0.00e+00	4896.00
IUUC-Pfo-096356	Poecilia formosa	81.71	0.00e+00	4576.00
IUUC-Pab-098240	Pongo abelii	97.91	0.00e+00	5178.00
IUUC-Pca-100994	Procavia capensis	94.05	0.00e+00	1643.00
IUUC-Pva-102263	Pteropus vampyrus	96.54	0.00e+00	5080.00
IUUC-Rno-104888	Rattus norvegicus	96.37	0.00e+00	5131.00
IUUC-Sha-106944	Sarcophilus harrisii	93.13	0.00e+00	5084.00
IUUC-Sar-113556	Sorex araneus	83.64	0.00e+00	984.00
IUUC-Tgu-116655	Taeniopygia guttata	92.17	0.00e+00	4966.00
IUUC-Tru-118093	Takifugu rubripes	84.77	0.00e+00	2902.00
IUUC-Tni-119739	Tetraodon nigroviridis	85.56	0.00e+00	1364.00
IUUC-Tbe-127962	Tupaia belangeri	91.74	0.00e+00	1201.00
IUUC-Ttr-128819	Tursiops truncatus	94.21	0.00e+00	2907.00
IUUC-Vpa-130482	Vicugna pacos	96.60	0.00e+00	2475.00
IUUC-Xtr-132222	Xenopus tropicalis	86.82	0.00e+00	4919.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence