iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059872

UUCD1 version

UUC-MeG-00187

Ensembl Protein ID

ENSMGAP00000003511.1

UniProt Accession

G1MXE8; G1MXE8_MELGA

Protein Name

Uncharacterized protein

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000003766.1	ENSMGAT00000004215.1	ENSMGAP00000003511.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.50e-44	145.2	230	268
UBD/Beta-Prp	6.90e-76	255.0	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v  +af +d t++vs+s D+++kvWD  t ++++
   Q: 230  GHGSWVLNVAFcPDdTHFVSSSSDKSVKVWDAGTRTCVH 268
           8***********777****************88877776 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    +++++ +++gs d+ +kvw++ ++kl   ++l+gh+ +v +v++s++g+i +++s D++i++wdl+tgk++ 
   Q: 12   EQAHDDAIWSVAWgknkKDGSETVISGSLDDLVKVWKWNDEKLdlQWTLEGHQLGVVSVDISHTGSIAASSSLDAHIRLWDLETGKQIK 100
           5677888888999988888899********************9999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   +++sl+fsp++++l++Gsh+  ++++ +etg++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWSLAFSPDSQFLATGSHVGKVNIFGVETGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd  ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHGSWVLNVAFCPDDTHFVSSSSDKSVKVWDAGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 277  VWGVKY-NGSGSKIVSVGDDQEIHIYDC 303
           ******.999****************97 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MTTQYGILFK QEQAHDDAIW SVAWGKNKKD GSETVISGSL DDLVKVWKWN DEKLDLQWTL 60
EGHQLGVVSV DISHTGSIAA SSSLDAHIRL WDLETGKQIK SIDAGPVDAW SLAFSPDSQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCGTTCCT GCTGAGGTCG CTTCCTCTCA GACATGACCA CACAGGTAAA TCAAAACATA 60
GCATTACTCA GACTGATCGC TACTTGGATG GATTTTTATG CTTTTTATGC ATAATACCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

mgp:100548811

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	33.83	1.00e-46	179.00
IUUC-Aml-002245	Ailuropoda melanoleuca	93.11	9.00e-160	555.00
IUUC-Atr-003142	Amborella trichopoda	50.93	1.00e-37	149.00
IUUC-Apl-003179	Anas platyrhynchos	97.05	1.00e-165	574.00
IUUC-Aca-004880	Anolis carolinensis	91.15	1.00e-161	561.00
IUUC-Aly-005956	Arabidopsis lyrata	38.66	2.00e-57	215.00
IUUC-Ath-007230	Arabidopsis thaliana	37.82	3.00e-52	198.00
IUUC-Acl-008297	Aspergillus clavatus	29.75	5.00e-26	111.00
IUUC-Ame-011511	Astyanax mexicanus	85.99	8.00e-153	532.00
IUUC-Bgr-012189	Blumeria graminis	31.90	1.00e-30	126.00
IUUC-Bta-012936	Bos taurus	93.44	8.00e-160	555.00
IUUC-Bdi-015020	Brachypodium distachyon	37.85	2.00e-46	178.00
IUUC-Bol-015927	Brassica oleracea	38.46	4.00e-58	217.00
IUUC-Bra-017323	Brassica rapa	38.66	1.00e-57	216.00
IUUC-Cja-019961	Callithrix jacchus	93.44	4.00e-160	556.00
IUUC-Cfa-020862	Canis familiaris	92.79	6.00e-159	552.00
IUUC-Cpo-021356	Cavia porcellus	93.05	8.00e-158	548.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.25	2.00e-57	215.00
IUUC-Csa-024067	Chlorocebus sabaeus	93.11	1.00e-159	555.00
IUUC-Cho-024421	Choloepus hoffmanni	79.80	2.00e-80	290.00
IUUC-Cin-025261	Ciona intestinalis	64.26	3.00e-117	414.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.62	2.00e-29	122.00
IUUC-Cne-026846	Cryptococcus neoformans	27.92	6.00e-23	100.00
IUUC-Dre-027706	Danio rerio	66.56	3.00e-113	400.00
IUUC-Dno-029084	Dasypus novemcinctus	92.51	4.00e-158	550.00
IUUC-Dor-030353	Dipodomys ordii	78.99	4.00e-117	413.00
IUUC-Dme-031836	Drosophila melanogaster	51.08	2.00e-87	315.00
IUUC-Ete-032261	Echinops telfairi	90.49	5.00e-154	536.00
IUUC-Eca-034231	Equus caballus	85.25	7.00e-144	502.00
IUUC-Eeu-034828	Erinaceus europaeus	92.78	2.00e-149	520.00
IUUC-Fca-036569	Felis catus	93.44	2.00e-159	553.00
IUUC-Fal-037469	Ficedula albicollis	98.69	5.00e-169	585.00
IUUC-Fox-038047	Fusarium oxysporum	33.45	3.00e-29	122.00
IUUC-Gmo-039579	Gadus morhua	84.26	9.00e-148	515.00
IUUC-Gga-040808	Gallus gallus	100.00	3.00e-162	563.00
IUUC-Gac-042100	Gasterosteus aculeatus	87.21	7.00e-152	529.00
IUUC-Gma-044408	Glycine max	40.94	3.00e-61	228.00
IUUC-Ggo-045227	Gorilla gorilla	93.44	4.00e-160	556.00
IUUC-Hsa-045839	Homo sapiens	93.44	4.00e-160	556.00
IUUC-Hvu-047591	Hordeum vulgare	37.74	9.00e-49	186.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	93.11	8.00e-160	555.00
IUUC-Lch-049549	Latimeria chalumnae	84.59	6.00e-149	519.00
IUUC-Lpe-050746	Leersia perrieri	38.26	2.00e-47	182.00
IUUC-Loc-052540	Lepisosteus oculatus	87.87	4.00e-152	529.00
IUUC-Lma-052992	Leptosphaeria maculans	28.91	4.00e-27	114.00
IUUC-Laf-053907	Loxodonta africana	93.11	8.00e-160	555.00
IUUC-Mcc-055828	Macaca mulatta	87.38	6.00e-156	542.00
IUUC-Meu-056075	Macropus eugenii	96.06	4.00e-136	476.00
IUUC-Mor-056971	Magnaporthe oryzae	31.84	6.00e-25	107.00
IUUC-Mtr-057728	Medicago truncatula	41.35	5.00e-59	220.00
IUUC-Mvi-060564	Microbotryum violaceum	32.21	2.00e-31	129.00
IUUC-Mmr-060985	Microcebus murinus	93.84	6.00e-153	532.00
IUUC-Mdo-062758	Monodelphis domestica	91.45	5.00e-160	556.00
IUUC-Mmu-063580	Mus musculus	90.82	7.00e-157	545.00
IUUC-Mac-064880	Musa acuminata	40.19	1.00e-58	219.00
IUUC-Mpu-066577	Mustela putorius furo	92.79	1.00e-158	551.00
IUUC-Nle-069573	Nomascus leucogenys	93.44	4.00e-160	556.00
IUUC-Opr-070216	Ochotona princeps	92.69	5.00e-157	546.00
IUUC-Ont-071981	Oreochromis niloticus	86.89	1.00e-153	535.00
IUUC-Oan-073223	Ornithorhynchus anatinus	96.46	4.00e-110	389.00
IUUC-Ocu-074199	Oryctolagus cuniculus	79.67	4.00e-131	459.00
IUUC-Oba-075255	Oryza barthii	40.00	3.00e-41	161.00
IUUC-Obr-076168	Oryza brachyantha	46.58	5.00e-35	140.00
IUUC-Ogl-077777	Oryza glaberrima	38.06	5.00e-48	184.00
IUUC-Ogu-078780	Oryza glumaepatula	38.06	5.00e-48	184.00
IUUC-Oin-079228	Oryza indica	38.06	1.00e-50	192.00
IUUC-Olo-080617	Oryza longistaminata	45.07	1.00e-28	118.00
IUUC-Ome-081421	Oryza meridionalis	38.06	3.00e-47	181.00
IUUC-Oni-082997	Oryza nivara	38.06	1.00e-50	192.00
IUUC-Opu-083931	Oryza punctata	38.39	6.00e-48	184.00
IUUC-Oru-084645	Oryza rufipogon	38.06	5.00e-48	184.00
IUUC-Osa-085842	Oryza sativa	38.06	1.00e-50	192.00
IUUC-Ola-086696	Oryzias latipes	87.21	4.00e-150	523.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	2.00e-41	161.00
IUUC-Oga-088272	Otolemur garnettii	92.76	8.00e-158	548.00
IUUC-Oar-089416	Ovis aries	93.44	8.00e-160	555.00
IUUC-Ptr-090944	Pan troglodytes	93.44	4.00e-160	556.00
IUUC-Pan-091861	Papio anubis	93.44	4.00e-160	556.00
IUUC-Psi-093750	Pelodiscus sinensis	97.05	2.00e-166	577.00
IUUC-Pma-094608	Petromyzon marinus	82.26	2.00e-139	488.00
IUUC-Pno-094832	Phaeosphaeria nodorum	36.81	5.00e-26	111.00
IUUC-Ppa-095737	Physcomitrella patens	39.74	5.00e-57	214.00
IUUC-Pfo-096479	Poecilia formosa	88.20	6.00e-147	512.00
IUUC-Pab-098179	Pongo abelii	93.44	4.00e-160	556.00
IUUC-Pop-099532	Populus trichocarpa	41.26	2.00e-57	214.00
IUUC-Pca-100664	Procavia capensis	72.46	2.00e-100	358.00
IUUC-Ppe-102056	Prunus persica	39.61	4.00e-58	217.00
IUUC-Pva-102859	Pteropus vampyrus	93.11	1.00e-158	551.00
IUUC-Pte-104236	Pyrenophora teres	36.26	2.00e-25	108.00
IUUC-Rno-105826	Rattus norvegicus	90.82	3.00e-156	543.00
IUUC-Sha-106660	Sarcophilus harrisii	93.36	6.00e-153	532.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.55	2.00e-36	145.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.07	7.00e-35	140.00
IUUC-Smo-109234	Selaginella moellendorffii	42.81	5.00e-62	230.00
IUUC-Sit-110048	Setaria italica	36.77	6.00e-40	157.00
IUUC-Sly-111618	Solanum lycopersicum	38.78	7.00e-53	200.00
IUUC-Stu-112543	Solanum tuberosum	38.46	1.00e-55	209.00
IUUC-Sar-113743	Sorex araneus	73.44	8.00e-123	432.00
IUUC-Sbi-114309	Sorghum bicolor	38.83	1.00e-41	162.00
IUUC-Ssc-115560	Sus scrofa	88.20	3.00e-148	516.00
IUUC-Tgu-117300	Taeniopygia guttata	99.02	1.00e-169	587.00
IUUC-Tru-117933	Takifugu rubripes	87.54	2.00e-153	534.00
IUUC-Tsy-119574	Tarsius syrichta	82.30	2.00e-135	474.00
IUUC-Tni-120191	Tetraodon nigroviridis	88.61	2.00e-114	404.00
IUUC-Tca-120983	Theobroma cacao	40.78	9.00e-59	219.00
IUUC-Tae-124056	Triticum aestivum	36.77	1.00e-48	186.00
IUUC-Tur-126711	Triticum urartu	36.66	3.00e-47	181.00
IUUC-Tme-127066	Tuber melanosporum	34.57	2.00e-35	142.00
IUUC-Tbe-127802	Tupaia belangeri	93.44	2.00e-159	553.00
IUUC-Ttr-128861	Tursiops truncatus	89.68	3.00e-52	198.00
IUUC-Vda-129720	Verticillium dahliae	29.97	3.00e-24	105.00
IUUC-Vpa-130618	Vicugna pacos	89.47	2.00e-127	447.00
IUUC-Vvi-130981	Vitis vinifera	40.71	2.00e-57	215.00
IUUC-Xtr-132460	Xenopus tropicalis	88.52	1.00e-150	525.00
IUUC-Xma-134154	Xiphophorus maculatus	88.20	4.00e-147	513.00
IUUC-Yli-134554	Yarrowia lipolytica	29.89	3.00e-23	101.00
IUUC-Zma-135097	Zea mays	36.15	8.00e-36	143.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence