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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063180
Ensembl Protein ID ENSMUSP00000027251.6
UniProt Accession Q920Q2; Q9QXV2; REV1_MOUSE
Genbank Protein ID BAB64933.1; AAF23323.1; AAH58093.1
Protein Name DNA repair protein REV1; Rev1-like terminal deoxycytidyl transferase
Genbank Nucleotide ID AB057418; AF179302; BC058093
Gene Name Rev1; Rev1l
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000026082.11 ENSMUST00000027251.11 ENSMUSP00000027251.6
ENSMUSG00000026082.11 ENSMUST00000194815.5 ENSMUSP00000141815.1
ENSMUSG00000026082.11 ENSMUST00000193472.1 ENSMUSP00000141875.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBM 2.60e-19 69.3 1012 1040
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBM
   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDp Vf++LP+e+Q+E++a+++q++
   Q: 1012 AFSQVDPDVFAALPAELQKELKAAYDQRQ 1040
           59*************************98 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MRRGGWRKRT ENDGWEKWGG YMAAKVQKLE EQFRTDAANQ KDGTASAIFS GVAIYVNGYT 60
DPSAEELRNL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063180|UBD,UBM|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGTCGCCT CGGGCCGGGC GCGAGCAGCG CGCGTGCGCC GCGCCCGGTG AGTGCGTGCG 60
GGGCCGGGCC AGCGGGCCGC GGTGTGGATG GGAGGGGGAG CCGGGCGCGC GCCAGAGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063180|UBD,UBM|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0046872--F:metal ion binding
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV
KEGG mmu:56210
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 38.00 3.00e-30 127.00
IUUC-Aml-001185 Ailuropoda melanoleuca 81.04 0.00e+00 2011.00
IUUC-Atr-002915 Amborella trichopoda 31.14 2.00e-102 367.00
IUUC-Apl-004054 Anas platyrhynchos 72.56 0.00e+00 1729.00
IUUC-Aca-004304 Anolis carolinensis 67.35 0.00e+00 1622.00
IUUC-Aly-005696 Arabidopsis lyrata 34.83 1.00e-85 311.00
IUUC-Ath-006893 Arabidopsis thaliana 35.55 2.00e-86 314.00
IUUC-Ago-007722 Ashbya gossypii 28.96 1.00e-40 161.00
IUUC-Acl-008347 Aspergillus clavatus 38.00 1.00e-86 315.00
IUUC-Afl-008444 Aspergillus flavus 37.50 2.00e-87 317.00
IUUC-Afu-008837 Aspergillus fumigatus 28.48 3.00e-87 317.00
IUUC-Ani-009188 Aspergillus nidulans 38.28 3.00e-91 330.00
IUUC-Ang-009866 Aspergillus niger 34.09 4.00e-98 353.00
IUUC-Aor-010107 Aspergillus oryzae 37.50 4.00e-87 316.00
IUUC-Ate-010359 Aspergillus terreus 32.12 3.00e-93 337.00
IUUC-Ame-010664 Astyanax mexicanus 50.15 0.00e+00 1125.00
IUUC-Bgr-012244 Blumeria graminis 31.12 8.00e-83 302.00
IUUC-Bta-013405 Bos taurus 77.10 0.00e+00 1754.00
IUUC-Bci-013849 Botrytis cinerea 31.39 7.00e-87 316.00
IUUC-Bdi-014066 Brachypodium distachyon 36.21 8.00e-84 305.00
IUUC-Bol-015544 Brassica oleracea 31.01 1.00e-89 324.00
IUUC-Bra-017792 Brassica rapa 31.28 3.00e-84 306.00
IUUC-Cel-018148 Caenorhabditis elegans 36.44 5.00e-82 299.00
IUUC-Cja-019742 Callithrix jacchus 71.78 0.00e+00 1444.00
IUUC-Cfa-020112 Canis familiaris 81.90 0.00e+00 2043.00
IUUC-Cpo-022152 Cavia porcellus 82.09 0.00e+00 2068.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 30.74 1.00e-50 194.00
IUUC-Csa-023504 Chlorocebus sabaeus 83.09 0.00e+00 2050.00
IUUC-Cho-024780 Choloepus hoffmanni 65.47 0.00e+00 722.00
IUUC-Cin-025276 Ciona intestinalis 41.45 1.00e-111 397.00
IUUC-Csv-026283 Ciona savignyi 43.69 9.00e-113 400.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 28.22 4.00e-90 326.00
IUUC-Cne-027079 Cryptococcus neoformans 33.97 4.00e-79 290.00
IUUC-Cme-027346 Cyanidioschyzon merolae 26.75 2.00e-46 181.00
IUUC-Dre-028073 Danio rerio 49.59 0.00e+00 1097.00
IUUC-Dno-030038 Dasypus novemcinctus 78.49 0.00e+00 1921.00
IUUC-Dor-031100 Dipodomys ordii 81.17 0.00e+00 1493.00
IUUC-Dse-031310 Dothistroma septosporum 29.29 6.00e-82 299.00
IUUC-Dme-031991 Drosophila melanogaster 41.82 1.00e-110 394.00
IUUC-Ete-033082 Echinops telfairi 72.13 0.00e+00 1347.00
IUUC-Eca-033471 Equus caballus 82.07 0.00e+00 2021.00
IUUC-Eeu-034993 Erinaceus europaeus 81.26 0.00e+00 1365.00
IUUC-Fca-035367 Felis catus 82.61 0.00e+00 1949.00
IUUC-Fal-036973 Ficedula albicollis 72.20 0.00e+00 1667.00
IUUC-Fox-037677 Fusarium oxysporum 29.63 1.00e-85 311.00
IUUC-Fso-038252 Fusarium solani 28.06 2.00e-91 330.00
IUUC-Gmo-039669 Gadus morhua 61.07 2.00e-172 599.00
IUUC-Ggr-039988 Gaeumannomyces graminis 27.24 2.00e-97 350.00
IUUC-Gga-040423 Gallus gallus 72.87 0.00e+00 1717.00
IUUC-Gac-042134 Gasterosteus aculeatus 48.14 0.00e+00 793.00
IUUC-Gma-042929 Glycine max 35.70 5.00e-88 319.00
IUUC-Ggo-044528 Gorilla gorilla 83.09 0.00e+00 2052.00
IUUC-Hsa-046259 Homo sapiens 83.01 0.00e+00 2024.00
IUUC-Hvu-047139 Hordeum vulgare 35.62 8.00e-56 211.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 83.73 0.00e+00 2087.00
IUUC-Kpa-049169 Komagataella pastoris 29.67 7.00e-62 232.00
IUUC-Lch-050471 Latimeria chalumnae 63.74 0.00e+00 1506.00
IUUC-Lpe-050800 Leersia perrieri 33.49 1.00e-84 308.00
IUUC-Loc-052320 Lepisosteus oculatus 46.72 0.00e+00 929.00
IUUC-Lma-053149 Leptosphaeria maculans 29.38 5.00e-88 319.00
IUUC-Laf-053810 Loxodonta africana 77.50 0.00e+00 1836.00
IUUC-Mcc-055574 Macaca mulatta 82.78 0.00e+00 2010.00
IUUC-Meu-055945 Macropus eugenii 61.27 0.00e+00 1085.00
IUUC-Mor-057195 Magnaporthe oryzae 30.74 7.00e-90 325.00
IUUC-Mpo-057488 Magnaporthe poae 34.23 2.00e-84 307.00
IUUC-Mtr-057955 Medicago truncatula 36.07 1.00e-90 328.00
IUUC-Mla-059027 Melampsora laricipopulina 32.71 2.00e-79 290.00
IUUC-Mga-060156 Meleagris gallopavo 72.63 0.00e+00 1725.00
IUUC-Mvi-060398 Microbotryum violaceum 35.26 1.00e-80 295.00
IUUC-Mmr-061113 Microcebus murinus 83.19 0.00e+00 2029.00
IUUC-Mdo-063001 Monodelphis domestica 77.32 0.00e+00 1885.00
IUUC-Mac-065551 Musa acuminata 36.98 8.00e-53 201.00
IUUC-Mpu-066525 Mustela putorius furo 81.12 0.00e+00 2016.00
IUUC-Mlu-067877 Myotis lucifugus 81.74 0.00e+00 1995.00
IUUC-Nfi-068418 Neosartorya fischeri 29.32 9.00e-90 325.00
IUUC-Ncr-068648 Neurospora crassa 31.96 3.00e-86 313.00
IUUC-Nle-069959 Nomascus leucogenys 84.21 0.00e+00 2038.00
IUUC-Opr-070522 Ochotona princeps 79.11 0.00e+00 1149.00
IUUC-Ont-072293 Oreochromis niloticus 48.50 0.00e+00 811.00
IUUC-Oan-073519 Ornithorhynchus anatinus 75.36 0.00e+00 1825.00
IUUC-Ocu-074492 Oryctolagus cuniculus 80.83 0.00e+00 1844.00
IUUC-Oba-075567 Oryza barthii 33.17 1.00e-86 315.00
IUUC-Obr-076332 Oryza brachyantha 36.08 6.00e-84 305.00
IUUC-Ogl-077348 Oryza glaberrima 33.17 2.00e-86 314.00
IUUC-Ogu-078779 Oryza glumaepatula 32.85 9.00e-86 311.00
IUUC-Oin-079738 Oryza indica 30.63 6.00e-75 276.00
IUUC-Olo-080701 Oryza longistaminata 30.63 4.00e-75 276.00
IUUC-Ome-081708 Oryza meridionalis 32.79 2.00e-83 304.00
IUUC-Oni-082251 Oryza nivara 32.85 1.00e-83 305.00
IUUC-Opu-083528 Oryza punctata 32.26 4.00e-78 286.00
IUUC-Oru-084293 Oryza rufipogon 32.38 2.00e-81 298.00
IUUC-Osa-085549 Oryza sativa 33.17 3.00e-86 313.00
IUUC-Ola-086793 Oryzias latipes 46.56 0.00e+00 1009.00
IUUC-Olu-087786 Ostreococcus lucimarinus 29.33 1.00e-59 224.00
IUUC-Oga-089006 Otolemur garnettii 82.46 0.00e+00 2021.00
IUUC-Oar-089597 Ovis aries 77.87 0.00e+00 1897.00
IUUC-Ptr-091520 Pan troglodytes 83.01 0.00e+00 2024.00
IUUC-Pan-092333 Papio anubis 82.93 0.00e+00 1999.00
IUUC-Psi-094004 Pelodiscus sinensis 74.09 0.00e+00 1782.00
IUUC-Pma-094128 Petromyzon marinus 54.69 3.00e-93 336.00
IUUC-Pno-094849 Phaeosphaeria nodorum 28.83 1.00e-79 291.00
IUUC-Ppa-095714 Physcomitrella patens 36.88 1.00e-89 325.00
IUUC-Pfo-096569 Poecilia formosa 52.47 0.00e+00 813.00
IUUC-Pab-097960 Pongo abelii 82.62 0.00e+00 2015.00
IUUC-Pop-098921 Populus trichocarpa 32.40 3.00e-82 300.00
IUUC-Pca-100509 Procavia capensis 63.68 0.00e+00 1125.00
IUUC-Ppe-101730 Prunus persica 33.45 1.00e-90 328.00
IUUC-Pva-102142 Pteropus vampyrus 80.72 0.00e+00 1973.00
IUUC-Pgr-103446 Puccinia graminis 31.65 3.00e-70 260.00
IUUC-Ptt-103849 Puccinia triticina 31.44 8.00e-76 279.00
IUUC-Pte-104128 Pyrenophora teres 30.10 6.00e-86 312.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 32.09 1.00e-82 301.00
IUUC-Rno-104871 Rattus norvegicus 90.81 0.00e+00 2231.00
IUUC-Sce-106236 Saccharomyces cerevisiae 27.52 2.00e-40 160.00
IUUC-Sha-106962 Sarcophilus harrisii 77.45 0.00e+00 1865.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 30.80 4.00e-62 233.00
IUUC-Spo-108170 Schizosaccharomyces pombe 33.26 5.00e-62 233.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 27.68 2.00e-107 384.00
IUUC-Smo-109554 Selaginella moellendorffii 37.27 4.00e-86 313.00
IUUC-Sit-110479 Setaria italica 41.50 3.00e-68 253.00
IUUC-Sly-111752 Solanum lycopersicum 37.37 2.00e-89 324.00
IUUC-Sar-113304 Sorex araneus 79.74 0.00e+00 1917.00
IUUC-Sbi-114196 Sorghum bicolor 41.18 1.00e-68 254.00
IUUC-Sre-115151 Sporisorium reilianum 31.05 4.00e-87 317.00
IUUC-Ssc-116104 Sus scrofa 80.43 0.00e+00 1961.00
IUUC-Tgu-117438 Taeniopygia guttata 72.61 0.00e+00 1712.00
IUUC-Tru-118553 Takifugu rubripes 47.93 0.00e+00 989.00
IUUC-Tsy-119056 Tarsius syrichta 78.28 0.00e+00 1856.00
IUUC-Tni-119933 Tetraodon nigroviridis 47.41 0.00e+00 794.00
IUUC-Tca-121376 Theobroma cacao 29.90 6.00e-86 312.00
IUUC-Tre-121972 Trichoderma reesei 28.95 5.00e-84 306.00
IUUC-Tvi-122342 Trichoderma virens 27.95 6.00e-80 292.00
IUUC-Tae-123898 Triticum aestivum 31.97 3.00e-103 370.00
IUUC-Tur-126735 Triticum urartu 36.27 3.00e-34 140.00
IUUC-Tme-126999 Tuber melanosporum 32.95 2.00e-79 291.00
IUUC-Tbe-127280 Tupaia belangeri 81.33 9.00e-128 451.00
IUUC-Ttr-129104 Tursiops truncatus 80.88 0.00e+00 1954.00
IUUC-Uma-129562 Ustilago maydis 30.53 3.00e-89 324.00
IUUC-Vda-129862 Verticillium dahliae 30.78 4.00e-89 323.00
IUUC-Vpa-130819 Vicugna pacos 78.65 0.00e+00 1043.00
IUUC-Vvi-131111 Vitis vinifera 35.31 4.00e-86 313.00
IUUC-Xtr-132629 Xenopus tropicalis 59.92 0.00e+00 1359.00
IUUC-Xma-134065 Xiphophorus maculatus 51.92 0.00e+00 801.00
IUUC-Yli-134633 Yarrowia lipolytica 33.00 4.00e-64 240.00
IUUC-Zma-135176 Zea mays 35.81 8.00e-85 308.00
Created Date 25-Jun-2017

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