iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098762

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01193958

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000009374.2	ENSPPYT00000010929.2	ENSPPYP00000010515.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-19	68.4	311	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdD............gtikvWD 29
           gH  +v++l++ +d  ll+sG++D            ++i vW 
   Q: 311  GHRQEVCGLKWsTDhQLLASGGNDnkelvsthgysqNQILVWK 353
           8**********98889********7777777777777777776 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDQDYERRLL RQIVIQNENT MPRVTEMRRT LTPASSPVSS PSKHGDRFIP SRAGANWSVN 60
FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCGGTGTG TGGGGTAGGC GGGGGGCGTG GCCGCGATTC GCCGCGCGCC GGCGTGGGGG 60
CGTGGTCGGG TTGCGGGGGT GCGCGCGGCC GGCCGGGCGC GCGCGGCGGA GGGAGGGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002003	Ailuropoda melanoleuca	82.04	0.00e+00	633.00
IUUC-Apl-003212	Anas platyrhynchos	85.79	0.00e+00	680.00
IUUC-Ame-011011	Astyanax mexicanus	80.65	2.00e-171	595.00
IUUC-Bta-012586	Bos taurus	87.03	0.00e+00	687.00
IUUC-Cja-019929	Callithrix jacchus	88.03	0.00e+00	692.00
IUUC-Cfa-020977	Canis familiaris	86.78	0.00e+00	685.00
IUUC-Cpo-021537	Cavia porcellus	86.78	0.00e+00	685.00
IUUC-Csa-023389	Chlorocebus sabaeus	88.28	0.00e+00	694.00
IUUC-Cin-025327	Ciona intestinalis	54.52	9.00e-101	360.00
IUUC-Csv-025921	Ciona savignyi	52.18	6.00e-110	390.00
IUUC-Dre-027470	Danio rerio	78.22	4.00e-167	580.00
IUUC-Dno-029629	Dasypus novemcinctus	77.81	3.00e-168	584.00
IUUC-Dor-030187	Dipodomys ordii	73.82	2.00e-165	575.00
IUUC-Dme-031858	Drosophila melanogaster	59.50	5.00e-115	407.00
IUUC-Ete-032562	Echinops telfairi	70.57	9.00e-151	526.00
IUUC-Eca-034210	Equus caballus	87.03	0.00e+00	688.00
IUUC-Fca-035839	Felis catus	80.30	0.00e+00	630.00
IUUC-Fal-036895	Ficedula albicollis	85.54	0.00e+00	678.00
IUUC-Gmo-039544	Gadus morhua	75.99	1.00e-161	563.00
IUUC-Gga-041025	Gallus gallus	85.54	0.00e+00	678.00
IUUC-Gac-041596	Gasterosteus aculeatus	77.48	3.00e-165	574.00
IUUC-Ggo-045599	Gorilla gorilla	88.03	0.00e+00	657.00
IUUC-Hsa-046695	Homo sapiens	88.28	0.00e+00	694.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	86.28	0.00e+00	681.00
IUUC-Lch-049827	Latimeria chalumnae	83.79	0.00e+00	629.00
IUUC-Loc-052856	Lepisosteus oculatus	81.39	2.00e-175	608.00
IUUC-Laf-054321	Loxodonta africana	63.21	3.00e-142	498.00
IUUC-Mcc-055601	Macaca mulatta	88.28	0.00e+00	694.00
IUUC-Meu-056276	Macropus eugenii	53.76	3.00e-98	352.00
IUUC-Mga-060097	Meleagris gallopavo	78.52	3.00e-175	607.00
IUUC-Mmr-061151	Microcebus murinus	76.06	2.00e-162	565.00
IUUC-Mdo-063062	Monodelphis domestica	85.29	0.00e+00	679.00
IUUC-Mmu-063731	Mus musculus	86.28	0.00e+00	682.00
IUUC-Mpu-066173	Mustela putorius furo	86.53	0.00e+00	686.00
IUUC-Mlu-068030	Myotis lucifugus	87.03	0.00e+00	687.00
IUUC-Nle-070163	Nomascus leucogenys	88.28	0.00e+00	696.00
IUUC-Opr-070974	Ochotona princeps	72.84	8.00e-95	339.00
IUUC-Ont-072272	Oreochromis niloticus	77.97	1.00e-165	576.00
IUUC-Oan-073634	Ornithorhynchus anatinus	80.00	2.00e-111	395.00
IUUC-Ola-087094	Oryzias latipes	77.09	2.00e-154	538.00
IUUC-Oga-088911	Otolemur garnettii	87.53	0.00e+00	689.00
IUUC-Oar-089508	Ovis aries	87.03	0.00e+00	687.00
IUUC-Ptr-090967	Pan troglodytes	96.43	0.00e+00	786.00
IUUC-Pan-092147	Papio anubis	88.28	0.00e+00	694.00
IUUC-Psi-093702	Pelodiscus sinensis	85.36	0.00e+00	677.00
IUUC-Pma-094581	Petromyzon marinus	69.76	8.00e-145	506.00
IUUC-Pfo-096309	Poecilia formosa	78.22	5.00e-166	577.00
IUUC-Pca-100565	Procavia capensis	78.84	1.00e-164	572.00
IUUC-Pva-102602	Pteropus vampyrus	84.04	0.00e+00	647.00
IUUC-Rno-105028	Rattus norvegicus	85.79	0.00e+00	678.00
IUUC-Sha-107107	Sarcophilus harrisii	68.98	2.00e-149	522.00
IUUC-Sar-112962	Sorex araneus	79.25	7.00e-69	253.00
IUUC-Ssc-116171	Sus scrofa	86.78	0.00e+00	686.00
IUUC-Tgu-116878	Taeniopygia guttata	72.93	3.00e-159	554.00
IUUC-Tru-118222	Takifugu rubripes	77.48	1.00e-164	572.00
IUUC-Tni-119863	Tetraodon nigroviridis	77.72	3.00e-163	568.00
IUUC-Tbe-128056	Tupaia belangeri	72.06	1.00e-107	382.00
IUUC-Ttr-129055	Tursiops truncatus	86.03	0.00e+00	674.00
IUUC-Xtr-132808	Xenopus tropicalis	80.30	0.00e+00	641.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence