iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118022

UUCD1 version

UUC-TaR-01162

Ensembl Protein ID

ENSTRUP00000027492.1

UniProt Accession

H2TS34; H2TS34_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp18; LOC101071687

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010878.1	ENSTRUT00000027601.1	ENSTRUP00000027492.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.80e-55	188.7	28	331

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.llkalkkeaeefsgyeq 89
           Gl+N++ +C +N++LQ+ s++ el+ell + ++  ++e      ++++  +l++++ ++ ks +    p++ +l +l+   ++++ + q
   Q: 28   GLSNHCLSCCVNALLQAFSATWELAELLDKWETAGVRE-----ADENIPLNLRRVLVAM-KSARPLLPPHKdFLLCLE--RNRIRRNTQ 108
           9*****************************66666664.....5789************.666666666553877776..56688**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da  ++ f+l+++ +++                          ++++    +++l++++++++++c +c + + + +  l l+lpv++
   Q: 109  HDADQVFLFILNAVVQQI--------------------------DNRSLALEVQNLYKISTETHLQCSSCSSAQIQSSYLLNLQLPVKE 171
           ******************..........................56777788************************************9 PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           +++    sl+ cL s+++ eel+gen ++c+kc  ++ ++  +kl +lP+vL++ +kRf  + + +  +k++  v+fp+++d s+++ +
   Q: 172  EHD----SLEGCLTSYFRHEELQGENCCFCPKCGTQTPSKWGVKLLSLPQVLCISFKRF--RGNLDGTRKLHCVVTFPESFDFSEVVKE 254
           997....8***************************************************..88889999***************98888 PP
   S: 268  ..peekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg....staYvlfYkr 337
              ++  ++ + Y L+avvvH G++s+GHY+a+v++ +++ W++ dDs+V+ v++eev++  g    +taY+l+Y+r
   Q: 255  afASSFTQNGCGYTLYAVVVHAGNASCGHYTAFVRHPSDQhWYHADDSRVKRVSWEEVKSAYGgssrDTAYMLMYRR 331
           55344455699*************************88888*******************988************97 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

ISEKWCKMKV FCLVPLGKAC SGRNGLRGLS NHCLSCCVNA LLQAFSATWE LAELLDKWET 60
AGVREADENI PLNLRRVLVA MKSARPLLPP HKDFLLCLER NRIRRNTQHD ADQVFLFILN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCAGAGA AATGGTGCAA AATGAAAGTG AAAGTGTGAC AGAGGCATTT CATTCCCAGC 60
TGAGGGGAGG GCTCTTTATT CCTCTATCAC ATCTCAGCTC CAGACCTTCG GATGGTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	32.78	6.00e-42	164.00
IUUC-Apl-004006	Anas platyrhynchos	35.42	6.00e-48	184.00
IUUC-Aca-005088	Anolis carolinensis	31.88	4.00e-39	155.00
IUUC-Ame-010606	Astyanax mexicanus	44.09	1.00e-71	263.00
IUUC-Bta-013036	Bos taurus	33.02	1.00e-43	170.00
IUUC-Cja-019052	Callithrix jacchus	32.92	2.00e-38	152.00
IUUC-Cfa-020554	Canis familiaris	32.40	3.00e-43	169.00
IUUC-Cpo-022421	Cavia porcellus	31.27	1.00e-45	177.00
IUUC-Csa-023737	Chlorocebus sabaeus	34.50	7.00e-28	116.00
IUUC-Dre-027408	Danio rerio	40.29	3.00e-68	252.00
IUUC-Dno-029813	Dasypus novemcinctus	27.36	2.00e-25	109.00
IUUC-Dor-030532	Dipodomys ordii	31.78	4.00e-40	158.00
IUUC-Ete-032254	Echinops telfairi	31.46	1.00e-40	160.00
IUUC-Eca-033482	Equus caballus	30.62	1.00e-39	156.00
IUUC-Fca-036313	Felis catus	33.02	4.00e-44	172.00
IUUC-Fal-037216	Ficedula albicollis	35.06	3.00e-49	189.00
IUUC-Gmo-038649	Gadus morhua	48.25	2.00e-78	285.00
IUUC-Gga-041082	Gallus gallus	35.19	1.00e-48	186.00
IUUC-Gac-042439	Gasterosteus aculeatus	63.78	2.00e-119	421.00
IUUC-Ggo-044957	Gorilla gorilla	32.32	1.00e-34	140.00
IUUC-Hsa-046381	Homo sapiens	31.76	1.00e-43	170.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	32.20	3.00e-42	166.00
IUUC-Loc-052688	Lepisosteus oculatus	40.31	1.00e-58	219.00
IUUC-Laf-054109	Loxodonta africana	32.70	1.00e-43	170.00
IUUC-Mcc-054814	Macaca mulatta	32.08	1.00e-43	170.00
IUUC-Meu-056253	Macropus eugenii	29.43	3.00e-30	125.00
IUUC-Mmr-061613	Microcebus murinus	34.48	3.00e-46	178.00
IUUC-Mdo-061890	Monodelphis domestica	31.03	8.00e-38	150.00
IUUC-Mmu-064329	Mus musculus	33.43	2.00e-41	162.00
IUUC-Mpu-066342	Mustela putorius furo	32.71	6.00e-46	177.00
IUUC-Mlu-067010	Myotis lucifugus	30.53	7.00e-39	154.00
IUUC-Nle-069148	Nomascus leucogenys	32.08	2.00e-44	172.00
IUUC-Opr-070988	Ochotona princeps	39.58	1.00e-24	107.00
IUUC-Ont-072039	Oreochromis niloticus	58.52	8.00e-111	393.00
IUUC-Ocu-074498	Oryctolagus cuniculus	32.60	3.00e-39	155.00
IUUC-Ola-086753	Oryzias latipes	58.25	5.00e-100	357.00
IUUC-Oga-088497	Otolemur garnettii	33.88	9.00e-46	177.00
IUUC-Oar-089505	Ovis aries	33.33	3.00e-43	168.00
IUUC-Ptr-091656	Pan troglodytes	31.45	5.00e-43	168.00
IUUC-Pan-092498	Papio anubis	32.08	1.00e-43	170.00
IUUC-Psi-093409	Pelodiscus sinensis	32.32	6.00e-42	164.00
IUUC-Pfo-096507	Poecilia formosa	56.96	1.00e-107	382.00
IUUC-Pab-097828	Pongo abelii	31.78	3.00e-42	165.00
IUUC-Pva-102972	Pteropus vampyrus	30.62	1.00e-38	153.00
IUUC-Rno-105738	Rattus norvegicus	33.54	3.00e-46	179.00
IUUC-Sha-107309	Sarcophilus harrisii	30.82	4.00e-36	145.00
IUUC-Sar-112983	Sorex araneus	30.91	4.00e-30	125.00
IUUC-Ssc-116049	Sus scrofa	32.81	4.00e-43	168.00
IUUC-Tgu-117115	Taeniopygia guttata	35.56	1.00e-48	186.00
IUUC-Tni-120306	Tetraodon nigroviridis	78.46	7.00e-141	493.00
IUUC-Ttr-128686	Tursiops truncatus	32.60	2.00e-39	156.00
IUUC-Xtr-132032	Xenopus tropicalis	32.21	8.00e-37	147.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence