iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068839

Ensembl Protein ID

EAA32827

UniProt Accession

Q7S906; DDI1_NEUCR

Genbank Protein ID

EAA32827.3

Protein Name

DNA damage-inducible protein 1

Genbank Nucleotide ID

CM002239

Gene Name

ddi-1; NCU05292

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU05292	EAA32827	EAA32827

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	8.40e-08	31.2	402	438
ULD/UDP/UBQ/UBQ_Other	8.30e-07	27.9	14	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraannnleaAveyLldg 41
           + +eqlv+ G d+++a++aL+a+++n+e A+ ++++g
   Q: 402  EHIEQLVALGADEQKAIRALEATDGNVEYAASLIFEG 438
           569******************************9986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 10   gs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekk 73
           +   l+l+v p++t  +L+  i+ +++ +p  q+L+  G+++ ++ ktL +++++dg+ + l +++
   Q: 14   DQdFLSLQVFPDMTLETLRNSIQAETSHHPSTQHLYHNGNLItDNSKTLTQLNVTDGDMLALHVRE 79
           44467888*******************************9999***************99988775 PP

Organism

Neurospora crassa

Functional Description
(View)

Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity).

Protein Sequence
(Fasta)

MQITIAIQDT TGDDQDFLSL QVFPDMTLET LRNSIQAETS HHPSTQHLYH NGNLITDNSK 60
TLTQLNVTDG DMLALHVRET QRATAVPESQ QGRPAAPPQQ DPEFLRLQFL ANPALRAEVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGTGCCTG CCTGCCCCAG AGCCCCTCAA TAACTGCCAC CCGCCCGGCC GCCTCCCTTC 60
ACTTTCTGGA ATCTTGAACT GTACAATTAC TCAGCCTTCT TGCCTTTTTT CCGTTTGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR001969--Aspartic_peptidase_AS
IPR033322--DDI1
IPR019103--Peptidase_aspartic_DDI1-type
IPR021109--Peptidase_aspartic_dom
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF09668--Asp_protease
PF00627--UBA
PF00240--ubiquitin

SMART

SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004190--F:aspartic-type endopeptidase activity
GO:0015031--P:protein transport

KEGG

ncr:NCU05292

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000989	Aegilops tauschii	40.12	4.00e-63	233.00
IUUC-Aml-001440	Ailuropoda melanoleuca	41.19	2.00e-60	224.00
IUUC-Atr-002722	Amborella trichopoda	35.01	2.00e-54	204.00
IUUC-Apl-003902	Anas platyrhynchos	42.29	1.00e-49	187.00
IUUC-Aca-004811	Anolis carolinensis	49.79	9.00e-56	208.00
IUUC-Aly-006104	Arabidopsis lyrata	50.00	5.00e-17	79.00
IUUC-Ath-007673	Arabidopsis thaliana	34.59	2.00e-62	230.00
IUUC-Ago-007981	Ashbya gossypii	38.84	1.00e-59	222.00
IUUC-Acl-008073	Aspergillus clavatus	54.57	5.00e-96	342.00
IUUC-Afl-008728	Aspergillus flavus	53.97	3.00e-110	389.00
IUUC-Afu-008934	Aspergillus fumigatus	56.47	5.00e-99	352.00
IUUC-Ani-009436	Aspergillus nidulans	53.98	7.00e-104	368.00
IUUC-Ang-009596	Aspergillus niger	62.60	2.00e-83	300.00
IUUC-Aor-009968	Aspergillus oryzae	53.70	1.00e-109	388.00
IUUC-Ate-010376	Aspergillus terreus	52.96	5.00e-93	332.00
IUUC-Ame-011570	Astyanax mexicanus	53.45	1.00e-58	218.00
IUUC-Bgr-012020	Blumeria graminis	52.67	3.00e-120	423.00
IUUC-Bta-012334	Bos taurus	40.62	1.00e-60	225.00
IUUC-Bci-013907	Botrytis cinerea	55.96	8.00e-126	441.00
IUUC-Bdi-014595	Brachypodium distachyon	35.06	2.00e-66	244.00
IUUC-Bol-015258	Brassica oleracea	34.38	7.00e-62	229.00
IUUC-Bra-016740	Brassica rapa	34.45	1.00e-61	229.00
IUUC-Cel-018415	Caenorhabditis elegans	37.65	2.00e-29	121.00
IUUC-Cja-018968	Callithrix jacchus	40.06	5.00e-60	223.00
IUUC-Cfa-020530	Canis familiaris	41.48	2.00e-60	224.00
IUUC-Cpo-022103	Cavia porcellus	35.79	4.00e-44	170.00
IUUC-Cre-022841	Chlamydomonas reinhardtii	35.52	2.00e-52	197.00
IUUC-Csa-023591	Chlorocebus sabaeus	41.09	3.00e-60	225.00
IUUC-Cho-024777	Choloepus hoffmanni	31.72	8.00e-32	129.00
IUUC-Cin-025396	Ciona intestinalis	51.69	8.00e-24	101.00
IUUC-Csv-026270	Ciona savignyi	46.72	6.00e-53	199.00
IUUC-Cgl-026570	Colletotrichum gloeosporioides	60.10	2.00e-116	410.00
IUUC-Cne-026974	Cryptococcus neoformans	39.10	4.00e-75	273.00
IUUC-Cme-027324	Cyanidioschyzon merolae	44.64	2.00e-36	144.00
IUUC-Dre-028030	Danio rerio	50.64	2.00e-56	211.00
IUUC-Dno-029264	Dasypus novemcinctus	41.08	3.00e-59	220.00
IUUC-Dor-030621	Dipodomys ordii	50.75	4.00e-13	67.00
IUUC-Dse-031180	Dothistroma septosporum	34.43	4.00e-24	103.00
IUUC-Dme-032067	Drosophila melanogaster	35.42	7.00e-57	213.00
IUUC-Ete-032664	Echinops telfairi	38.17	3.00e-39	153.00
IUUC-Eca-033648	Equus caballus	42.54	6.00e-58	216.00
IUUC-Eeu-035148	Erinaceus europaeus	37.75	3.00e-39	154.00
IUUC-Fca-035376	Felis catus	41.48	4.00e-60	223.00
IUUC-Fal-037492	Ficedula albicollis	26.47	5.00e-09	52.80
IUUC-Fox-037786	Fusarium oxysporum	59.19	9.00e-116	408.00
IUUC-Gmo-039324	Gadus morhua	39.17	4.00e-56	209.00
IUUC-Ggr-039750	Gaeumannomyces graminis	58.52	3.00e-127	446.00
IUUC-Gga-040917	Gallus gallus	58.93	2.00e-31	126.00
IUUC-Gac-041785	Gasterosteus aculeatus	52.24	7.00e-60	222.00
IUUC-Gma-043134	Glycine max	39.58	2.00e-61	227.00
IUUC-Ggo-044472	Gorilla gorilla	36.06	1.00e-41	162.00
IUUC-Hsa-046783	Homo sapiens	41.19	1.00e-60	224.00
IUUC-Hvu-047222	Hordeum vulgare	40.73	3.00e-64	236.00
IUUC-Itr-048836	Ictidomys tridecemlineatus	42.86	9.00e-57	211.00
IUUC-Kpa-049208	Komagataella pastoris	35.29	5.00e-61	226.00
IUUC-Lch-049953	Latimeria chalumnae	51.52	5.00e-55	207.00
IUUC-Lpe-050925	Leersia perrieri	34.84	3.00e-56	210.00
IUUC-Loc-052009	Lepisosteus oculatus	41.47	4.00e-56	210.00
IUUC-Lma-053305	Leptosphaeria maculans	48.55	2.00e-89	320.00
IUUC-Laf-054229	Loxodonta africana	39.77	1.00e-59	221.00
IUUC-Mcc-054796	Macaca mulatta	41.38	1.00e-60	226.00
IUUC-Meu-055944	Macropus eugenii	32.95	9.00e-40	155.00
IUUC-Mpo-057402	Magnaporthe poae	58.06	1.00e-128	451.00
IUUC-Mtr-058061	Medicago truncatula	31.25	5.00e-03	32.70
IUUC-Mla-058983	Melampsora laricipopulina	40.00	1.00e-18	84.70
IUUC-Mga-059910	Meleagris gallopavo	43.04	3.00e-55	207.00
IUUC-Mvi-060225	Microbotryum violaceum	54.02	1.00e-75	274.00
IUUC-Mmr-061679	Microcebus murinus	39.94	4.00e-49	186.00
IUUC-Mdo-062992	Monodelphis domestica	40.46	7.00e-61	225.00
IUUC-Mmu-063187	Mus musculus	40.06	1.00e-59	221.00
IUUC-Mac-064640	Musa acuminata	35.36	1.00e-65	241.00
IUUC-Mpu-066770	Mustela putorius furo	41.41	2.00e-46	177.00
IUUC-Mlu-067804	Myotis lucifugus	42.06	1.00e-58	218.00
IUUC-Nfi-068555	Neosartorya fischeri	56.76	8.00e-100	355.00
IUUC-Nle-069089	Nomascus leucogenys	41.38	1.00e-60	226.00
IUUC-Opr-070199	Ochotona princeps	37.16	1.00e-48	185.00
IUUC-Ont-072300	Oreochromis niloticus	52.07	4.00e-58	216.00
IUUC-Oan-073421	Ornithorhynchus anatinus	43.46	1.00e-56	211.00
IUUC-Ocu-074510	Oryctolagus cuniculus	36.73	5.00e-45	173.00
IUUC-Oba-075183	Oryza barthii	36.63	1.00e-64	238.00
IUUC-Obr-076044	Oryza brachyantha	35.43	2.00e-63	234.00
IUUC-Ogl-077284	Oryza glaberrima	36.40	1.00e-63	234.00
IUUC-Ogu-078171	Oryza glumaepatula	36.40	2.00e-63	234.00
IUUC-Oin-079871	Oryza indica	35.97	3.00e-64	237.00
IUUC-Olo-080579	Oryza longistaminata	35.76	2.00e-64	238.00
IUUC-Ome-081972	Oryza meridionalis	35.73	6.00e-64	236.00
IUUC-Oni-083027	Oryza nivara	36.40	1.00e-63	234.00
IUUC-Opu-083491	Oryza punctata	36.40	2.00e-63	234.00
IUUC-Oru-084589	Oryza rufipogon	36.40	1.00e-63	234.00
IUUC-Osa-085703	Oryza sativa	36.40	1.00e-63	234.00
IUUC-Ola-086911	Oryzias latipes	46.40	7.00e-21	92.40
IUUC-Olu-087654	Ostreococcus lucimarinus	42.39	7.00e-58	216.00
IUUC-Oga-089146	Otolemur garnettii	34.96	6.00e-35	139.00
IUUC-Oar-089924	Ovis aries	40.22	9.00e-61	225.00
IUUC-Ptr-090938	Pan troglodytes	41.19	1.00e-60	224.00
IUUC-Pan-091767	Papio anubis	41.19	1.00e-60	224.00
IUUC-Psi-093426	Pelodiscus sinensis	39.77	2.00e-58	218.00
IUUC-Pno-094977	Phaeosphaeria nodorum	48.53	1.00e-102	365.00
IUUC-Ppa-095744	Physcomitrella patens	41.64	5.00e-57	213.00
IUUC-Pfo-097404	Poecilia formosa	50.64	8.00e-55	205.00
IUUC-Pab-098128	Pongo abelii	41.19	1.00e-60	224.00
IUUC-Pop-099053	Populus trichocarpa	35.14	4.00e-59	220.00
IUUC-Pca-100554	Procavia capensis	55.97	3.00e-38	150.00
IUUC-Ppe-101690	Prunus persica	35.82	4.00e-62	229.00
IUUC-Pva-102638	Pteropus vampyrus	32.67	6.00e-36	142.00
IUUC-Pgr-103310	Puccinia graminis	73.33	2.00e-13	66.60
IUUC-Ptt-103798	Puccinia triticina	45.99	1.00e-72	265.00
IUUC-Pte-104408	Pyrenophora teres	50.99	2.00e-95	341.00
IUUC-Pyt-104420	Pyrenophora triticirepentis	47.61	5.00e-97	346.00
IUUC-Rno-105333	Rattus norvegicus	40.52	3.00e-58	218.00
IUUC-Sce-106167	Saccharomyces cerevisiae	33.87	2.00e-58	217.00
IUUC-Sha-107599	Sarcophilus harrisii	43.17	2.00e-57	214.00
IUUC-Sja-107968	Schizosaccharomyces japonicus	51.12	6.00e-61	226.00
IUUC-Spo-108130	Schizosaccharomyces pombe	43.18	1.00e-71	261.00
IUUC-Ssl-108671	Sclerotinia sclerotiorum	55.87	1.00e-122	431.00
IUUC-Sit-109819	Setaria italica	35.87	6.00e-66	243.00
IUUC-Sly-110983	Solanum lycopersicum	35.14	3.00e-57	213.00
IUUC-Stu-112218	Solanum tuberosum	34.10	3.00e-60	223.00
IUUC-Sar-113702	Sorex araneus	29.51	9.00e-10	54.70
IUUC-Sbi-114118	Sorghum bicolor	36.13	1.00e-64	238.00
IUUC-Sre-115084	Sporisorium reilianum	48.26	2.00e-65	241.00
IUUC-Ssc-115545	Sus scrofa	41.19	2.00e-60	224.00
IUUC-Tgu-117353	Taeniopygia guttata	39.32	1.00e-56	211.00
IUUC-Tru-117838	Takifugu rubripes	53.39	4.00e-60	223.00
IUUC-Tsy-118783	Tarsius syrichta	48.04	1.00e-36	145.00
IUUC-Tni-120287	Tetraodon nigroviridis	52.65	3.00e-60	223.00
IUUC-Tca-121513	Theobroma cacao	39.51	2.00e-58	217.00
IUUC-Tvi-122402	Trichoderma virens	51.43	3.00e-40	157.00
IUUC-Tae-125534	Triticum aestivum	40.12	2.00e-64	237.00
IUUC-Tur-126159	Triticum urartu	40.12	2.00e-61	227.00
IUUC-Tme-127088	Tuber melanosporum	50.25	4.00e-102	362.00
IUUC-Tbe-127948	Tupaia belangeri	35.20	3.00e-44	170.00
IUUC-Ttr-128560	Tursiops truncatus	40.34	3.00e-60	224.00
IUUC-Uma-129478	Ustilago maydis	56.17	2.00e-60	224.00
IUUC-Vda-129758	Verticillium dahliae	61.84	3.00e-111	393.00
IUUC-Vpa-130132	Vicugna pacos	58.44	1.00e-46	178.00
IUUC-Vvi-131006	Vitis vinifera	40.06	8.00e-58	215.00
IUUC-Xtr-132758	Xenopus tropicalis	43.03	4.00e-57	213.00
IUUC-Xma-133125	Xiphophorus maculatus	50.42	1.00e-53	201.00
IUUC-Yli-134530	Yarrowia lipolytica	34.81	5.00e-62	229.00
IUUC-Zma-135856	Zea mays	35.81	8.00e-64	235.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence