iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021963

Ensembl Protein ID

ENSCPOP00000020025.1

UniProt Accession

H0WAL3; H0WAL3_CAVPO

Genbank Protein ID

ENSCPOP00000020025

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AAKN02049580

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000024550.1	ENSCPOT00000028132.1	ENSCPOP00000020025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-06	28.3	187	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ +   ++   ll+s+s+D+t+++W++r+g++l+
   Q: 187  GHTEFVSRIMVvPGhpELLLSSSGDCTLRLWEYRSGRQLH 226
           566666666557444589******************9986 PP

Organism

Cavia porcellus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MASSVGLALC GQALVVRGGS RFLATSTASS DDGSLFTFDC SAAEKKVQEN KGEDGQPVDQ 60
GSDTILASTF SKSGSYFALT DDSKRLILFR TKPWQCLSVR SVVRRCTALT FTASEQRVLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAGTT CTGTAGGGCT GGCGTTGTGC GGGCAGGCGC TGGTGGTGCG GGGCGGCAGC 60
CGATTCCTGG CCACCTCCAC TGCGAGCAGG TGAGGGGGTC CTGGCTGGAA GCTGCGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	29.82	8.00e-13	68.20
IUUC-Apl-003975	Anas platyrhynchos	58.14	1.00e-119	422.00
IUUC-Aca-005170	Anolis carolinensis	51.87	6.00e-96	344.00
IUUC-Aly-005769	Arabidopsis lyrata	30.80	2.00e-24	106.00
IUUC-Ath-006733	Arabidopsis thaliana	30.40	8.00e-24	104.00
IUUC-Acl-008151	Aspergillus clavatus	32.74	2.00e-15	77.00
IUUC-Afl-008518	Aspergillus flavus	33.69	2.00e-15	76.60
IUUC-Afu-009102	Aspergillus fumigatus	27.09	1.00e-16	80.90
IUUC-Ani-009442	Aspergillus nidulans	28.24	4.00e-18	85.90
IUUC-Aor-010133	Aspergillus oryzae	28.57	5.00e-19	89.00
IUUC-Ate-010465	Aspergillus terreus	37.29	1.00e-14	74.30
IUUC-Ame-010613	Astyanax mexicanus	44.85	3.00e-83	302.00
IUUC-Bgr-012067	Blumeria graminis	29.44	8.00e-19	88.60
IUUC-Bta-012788	Bos taurus	78.61	1.00e-173	602.00
IUUC-Bdi-014458	Brachypodium distachyon	32.40	4.00e-18	85.90
IUUC-Bol-016398	Brassica oleracea	38.04	3.00e-24	105.00
IUUC-Bra-016644	Brassica rapa	37.91	4.00e-25	110.00
IUUC-Csa-024148	Chlorocebus sabaeus	79.95	2.00e-154	538.00
IUUC-Cne-026834	Cryptococcus neoformans	35.10	8.00e-20	92.00
IUUC-Dre-028427	Danio rerio	46.86	2.00e-85	308.00
IUUC-Dno-028881	Dasypus novemcinctus	68.49	9.00e-143	499.00
IUUC-Dor-030522	Dipodomys ordii	78.04	6.00e-166	576.00
IUUC-Dme-032136	Drosophila melanogaster	33.93	4.00e-22	99.00
IUUC-Fca-035833	Felis catus	75.92	2.00e-157	548.00
IUUC-Fal-037497	Ficedula albicollis	55.62	7.00e-112	397.00
IUUC-Gga-040547	Gallus gallus	54.99	4.00e-118	417.00
IUUC-Gac-041761	Gasterosteus aculeatus	42.82	1.00e-80	293.00
IUUC-Gma-043722	Glycine max	36.46	4.00e-20	92.40
IUUC-Ggo-045340	Gorilla gorilla	79.14	1.00e-165	575.00
IUUC-Hsa-046403	Homo sapiens	78.88	8.00e-166	576.00
IUUC-Hvu-047643	Hordeum vulgare	33.74	1.00e-21	97.80
IUUC-Itr-048103	Ictidomys tridecemlineatus	81.55	0.00e+00	629.00
IUUC-Kpa-049283	Komagataella pastoris	33.99	4.00e-20	92.00
IUUC-Lch-050682	Latimeria chalumnae	52.16	8.00e-103	367.00
IUUC-Lpe-050712	Leersia perrieri	32.79	9.00e-23	101.00
IUUC-Loc-052599	Lepisosteus oculatus	50.13	4.00e-102	364.00
IUUC-Laf-054390	Loxodonta africana	75.13	6.00e-167	580.00
IUUC-Mcc-054747	Macaca mulatta	78.61	3.00e-158	551.00
IUUC-Mtr-058600	Medicago truncatula	34.86	4.00e-24	105.00
IUUC-Mla-059129	Melampsora laricipopulina	25.13	1.00e-12	66.60
IUUC-Mga-059876	Meleagris gallopavo	56.23	2.00e-117	415.00
IUUC-Mvi-060359	Microbotryum violaceum	29.94	8.00e-13	68.90
IUUC-Mmr-061518	Microcebus murinus	76.20	5.00e-164	570.00
IUUC-Mac-065625	Musa acuminata	34.57	1.00e-20	94.00
IUUC-Nfi-068402	Neosartorya fischeri	26.27	1.00e-15	77.40
IUUC-Nle-069914	Nomascus leucogenys	78.07	1.00e-155	542.00
IUUC-Ont-071555	Oreochromis niloticus	40.31	4.00e-73	268.00
IUUC-Oan-072951	Ornithorhynchus anatinus	65.08	1.00e-135	476.00
IUUC-Ocu-074679	Oryctolagus cuniculus	79.68	1.00e-166	578.00
IUUC-Oba-075355	Oryza barthii	27.73	3.00e-12	66.60
IUUC-Obr-076769	Oryza brachyantha	34.16	2.00e-24	106.00
IUUC-Ogl-077168	Oryza glaberrima	33.74	3.00e-24	105.00
IUUC-Ogu-078275	Oryza glumaepatula	25.99	3.00e-12	66.60
IUUC-Oin-079207	Oryza indica	33.74	3.00e-24	105.00
IUUC-Oni-082437	Oryza nivara	26.86	5.00e-12	65.50
IUUC-Opu-084031	Oryza punctata	32.16	3.00e-22	99.80
IUUC-Oru-084380	Oryza rufipogon	26.98	3.00e-12	66.60
IUUC-Osa-085327	Oryza sativa	33.74	3.00e-24	105.00
IUUC-Ola-086716	Oryzias latipes	42.74	6.00e-74	271.00
IUUC-Olu-087708	Ostreococcus lucimarinus	27.75	6.00e-13	68.60
IUUC-Oar-090239	Ovis aries	78.31	7.00e-170	589.00
IUUC-Ptr-090851	Pan troglodytes	79.14	9.00e-166	576.00
IUUC-Pan-092558	Papio anubis	79.95	1.00e-155	542.00
IUUC-Psi-093792	Pelodiscus sinensis	56.22	1.00e-125	442.00
IUUC-Ppa-095757	Physcomitrella patens	37.84	1.00e-21	97.80
IUUC-Pfo-096465	Poecilia formosa	43.42	2.00e-80	292.00
IUUC-Pab-097722	Pongo abelii	78.31	2.00e-159	554.00
IUUC-Pop-098979	Populus trichocarpa	34.95	5.00e-20	92.40
IUUC-Pca-100753	Procavia capensis	68.80	2.00e-101	362.00
IUUC-Ppe-101515	Prunus persica	35.96	4.00e-20	92.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	26.69	7.00e-13	68.60
IUUC-Spo-108251	Schizosaccharomyces pombe	27.76	9.00e-15	74.70
IUUC-Smo-108938	Selaginella moellendorffii	39.38	9.00e-24	104.00
IUUC-Sit-110020	Setaria italica	34.74	3.00e-21	96.30
IUUC-Sly-111543	Solanum lycopersicum	32.64	2.00e-21	97.10
IUUC-Stu-111925	Solanum tuberosum	32.98	5.00e-21	95.10
IUUC-Sbi-114061	Sorghum bicolor	36.16	3.00e-21	96.30
IUUC-Tgu-117321	Taeniopygia guttata	54.94	3.00e-103	368.00
IUUC-Tru-118454	Takifugu rubripes	43.85	1.00e-78	286.00
IUUC-Tni-119894	Tetraodon nigroviridis	43.79	1.00e-69	256.00
IUUC-Tca-121746	Theobroma cacao	34.20	1.00e-20	94.00
IUUC-Tae-123054	Triticum aestivum	33.61	3.00e-22	99.40
IUUC-Tur-126254	Triticum urartu	29.11	5.00e-14	72.00
IUUC-Tbe-127683	Tupaia belangeri	51.85	1.00e-60	226.00
IUUC-Ttr-129056	Tursiops truncatus	74.87	5.00e-157	546.00
IUUC-Vvi-131428	Vitis vinifera	34.87	6.00e-22	98.60
IUUC-Xma-133605	Xiphophorus maculatus	43.42	5.00e-81	294.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence