iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005031

UUCD1 version

UUC-AnC-00997

Ensembl Protein ID

ENSACAP00000005799.3

UniProt Accession

H9GAQ1; H9GAQ1_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005889.3	ENSACAT00000005927.3	ENSACAP00000005799.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-98	328.8	35	364

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 35   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 116
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ ++++ e+++k+  ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 117  MQQDAHEFLNYLLNTVADIL---QEEKKQEKQNGRLRNGNMNETEENNKQDLTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 202
           ********************...34555555555556666667788888888************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 203  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 284
           ****.....9**********************************************************************66655..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts + + + ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 285  TSGD-AINLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 364
           7744.44559***************************.888*******************999*****************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MTVRNIASIC NMGTNASALE KDIGPEQFPL NEHYFGLVNF GNTCYCNSVL QALYFCRPFR 60
ENVLAYKAQQ KKKENLLTCL ADLFHSIATQ KKKVGVIPPK KFISRLRKEN DLFDNYMQQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGTCA GAAACATCGC CTCCATTTGT AATATGGTGA GTAGTCCTGG AGGGCAAGGG 60
CTGGGCTGGG CTTCTTTTGG GGAGAGCGGG GATGGGGTGC CAAAAGCAGG AGGTGGGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100562637

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002353	Ailuropoda melanoleuca	95.60	0.00e+00	690.00
IUUC-Atr-002650	Amborella trichopoda	58.97	2.00e-124	438.00
IUUC-Apl-003380	Anas platyrhynchos	94.81	0.00e+00	692.00
IUUC-Aly-005830	Arabidopsis lyrata	58.38	7.00e-122	429.00
IUUC-Ath-006663	Arabidopsis thaliana	58.11	1.00e-124	439.00
IUUC-Ago-007871	Ashbya gossypii	38.57	2.00e-48	187.00
IUUC-Ame-010862	Astyanax mexicanus	94.85	0.00e+00	729.00
IUUC-Bta-013023	Bos taurus	95.84	0.00e+00	687.00
IUUC-Bdi-014008	Brachypodium distachyon	60.27	5.00e-125	440.00
IUUC-Bol-015138	Brassica oleracea	58.60	1.00e-123	436.00
IUUC-Bra-016956	Brassica rapa	58.54	5.00e-125	440.00
IUUC-Cel-018379	Caenorhabditis elegans	62.41	2.00e-144	505.00
IUUC-Cja-018956	Callithrix jacchus	94.82	0.00e+00	685.00
IUUC-Cfa-021064	Canis familiaris	96.61	0.00e+00	676.00
IUUC-Cpo-022443	Cavia porcellus	96.36	0.00e+00	685.00
IUUC-Csa-023841	Chlorocebus sabaeus	97.27	0.00e+00	711.00
IUUC-Cne-026900	Cryptococcus neoformans	41.91	5.00e-60	225.00
IUUC-Dre-028230	Danio rerio	94.86	0.00e+00	726.00
IUUC-Dno-029209	Dasypus novemcinctus	94.79	0.00e+00	689.00
IUUC-Dme-032038	Drosophila melanogaster	81.09	1.00e-99	356.00
IUUC-Eca-033721	Equus caballus	97.46	0.00e+00	687.00
IUUC-Eeu-034916	Erinaceus europaeus	95.58	2.00e-158	551.00
IUUC-Fca-036299	Felis catus	94.81	0.00e+00	687.00
IUUC-Gmo-038611	Gadus morhua	94.35	0.00e+00	696.00
IUUC-Gga-041157	Gallus gallus	97.81	0.00e+00	716.00
IUUC-Gac-041764	Gasterosteus aculeatus	93.39	0.00e+00	708.00
IUUC-Gma-043101	Glycine max	59.29	2.00e-126	445.00
IUUC-Ggo-044659	Gorilla gorilla	95.10	0.00e+00	689.00
IUUC-Hsa-046156	Homo sapiens	97.27	0.00e+00	711.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	97.27	0.00e+00	711.00
IUUC-Kpa-049250	Komagataella pastoris	44.48	2.00e-69	256.00
IUUC-Lch-049969	Latimeria chalumnae	95.90	0.00e+00	681.00
IUUC-Lpe-051368	Leersia perrieri	58.70	6.00e-122	430.00
IUUC-Laf-054085	Loxodonta africana	97.27	0.00e+00	711.00
IUUC-Mcc-055566	Macaca mulatta	95.34	0.00e+00	689.00
IUUC-Mtr-057715	Medicago truncatula	59.84	4.00e-126	444.00
IUUC-Mla-059142	Melampsora laricipopulina	53.69	1.00e-94	341.00
IUUC-Mga-059575	Meleagris gallopavo	97.74	0.00e+00	690.00
IUUC-Mvi-060357	Microbotryum violaceum	53.60	1.00e-77	285.00
IUUC-Mdo-062579	Monodelphis domestica	97.27	0.00e+00	709.00
IUUC-Mmu-063611	Mus musculus	97.27	0.00e+00	711.00
IUUC-Mac-065323	Musa acuminata	59.83	1.00e-122	432.00
IUUC-Mpu-066038	Mustela putorius furo	97.18	0.00e+00	685.00
IUUC-Mlu-068183	Myotis lucifugus	95.60	0.00e+00	692.00
IUUC-Nle-069330	Nomascus leucogenys	97.27	0.00e+00	711.00
IUUC-Opr-070980	Ochotona princeps	96.89	0.00e+00	683.00
IUUC-Ont-072134	Oreochromis niloticus	95.12	0.00e+00	732.00
IUUC-Oan-073583	Ornithorhynchus anatinus	92.11	0.00e+00	681.00
IUUC-Ocu-074923	Oryctolagus cuniculus	97.18	0.00e+00	685.00
IUUC-Oba-075220	Oryza barthii	59.18	3.00e-122	431.00
IUUC-Obr-076088	Oryza brachyantha	58.36	4.00e-119	421.00
IUUC-Ogl-077216	Oryza glaberrima	59.18	3.00e-122	431.00
IUUC-Ogu-078836	Oryza glumaepatula	59.18	3.00e-122	431.00
IUUC-Oin-079522	Oryza indica	59.18	3.00e-122	431.00
IUUC-Olo-080882	Oryza longistaminata	59.18	3.00e-122	431.00
IUUC-Ome-081549	Oryza meridionalis	59.18	3.00e-122	431.00
IUUC-Oni-082982	Oryza nivara	59.18	3.00e-122	431.00
IUUC-Opu-083532	Oryza punctata	59.18	4.00e-122	431.00
IUUC-Oru-084568	Oryza rufipogon	59.18	3.00e-122	431.00
IUUC-Osa-085299	Oryza sativa	59.18	3.00e-122	431.00
IUUC-Ola-086546	Oryzias latipes	93.39	0.00e+00	705.00
IUUC-Oga-088073	Otolemur garnettii	97.46	0.00e+00	687.00
IUUC-Oar-089248	Ovis aries	97.18	0.00e+00	684.00
IUUC-Ptr-090814	Pan troglodytes	97.27	0.00e+00	711.00
IUUC-Pan-091753	Papio anubis	97.27	0.00e+00	711.00
IUUC-Psi-094012	Pelodiscus sinensis	97.74	0.00e+00	689.00
IUUC-Ppa-095415	Physcomitrella patens	58.76	4.00e-126	444.00
IUUC-Pfo-097369	Poecilia formosa	95.12	0.00e+00	732.00
IUUC-Pab-098594	Pongo abelii	97.18	0.00e+00	687.00
IUUC-Pop-099798	Populus trichocarpa	59.29	5.00e-125	440.00
IUUC-Pca-100913	Procavia capensis	80.85	7.00e-156	542.00
IUUC-Ppe-101474	Prunus persica	59.29	2.00e-126	445.00
IUUC-Pva-102892	Pteropus vampyrus	97.18	0.00e+00	685.00
IUUC-Rno-104909	Rattus norvegicus	96.99	0.00e+00	709.00
IUUC-Sha-107400	Sarcophilus harrisii	97.18	0.00e+00	684.00
IUUC-Smo-109064	Selaginella moellendorffii	60.06	4.00e-121	427.00
IUUC-Sit-110819	Setaria italica	59.45	2.00e-123	435.00
IUUC-Sly-111165	Solanum lycopersicum	59.07	8.00e-126	442.00
IUUC-Stu-112398	Solanum tuberosum	59.34	1.00e-125	442.00
IUUC-Sbi-114724	Sorghum bicolor	58.90	5.00e-123	433.00
IUUC-Ssc-115550	Sus scrofa	97.18	0.00e+00	685.00
IUUC-Tgu-116800	Taeniopygia guttata	97.81	0.00e+00	716.00
IUUC-Tru-118212	Takifugu rubripes	95.12	0.00e+00	733.00
IUUC-Tni-120071	Tetraodon nigroviridis	95.12	0.00e+00	733.00
IUUC-Tae-124807	Triticum aestivum	59.18	2.00e-125	441.00
IUUC-Tur-126563	Triticum urartu	59.18	2.00e-125	442.00
IUUC-Uma-129409	Ustilago maydis	50.17	8.00e-82	298.00
IUUC-Vpa-130590	Vicugna pacos	92.39	0.00e+00	639.00
IUUC-Vvi-131371	Vitis vinifera	59.84	1.00e-125	442.00
IUUC-Xma-133111	Xiphophorus maculatus	94.85	0.00e+00	730.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence