iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033721

UUCD1 version

UUC-EqC-01039

Ensembl Protein ID

ENSECAP00000007107.1

UniProt Accession

F6WU07; F6WU07_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000009006.1	ENSECAT00000009351.1	ENSECAP00000007107.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-98	329.9	23	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 23   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 104
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l+   +++k+e+++ + ++ ++++  +++k + ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 105  MQQDAHEFLNYLLNTIADILQ---EEKKQEKQNGKLKNGNMNETAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 190
           ********************3...3444444444445555556667777777************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 191  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 272
           ****.....9**********************************************************************66555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts++  ++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 273  TSSDA-VNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 352
           77554.4459***************************.888*******************999*****************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

GTNASALEKD IGPEQFPINE HYFGLVNFGN TCYCNSVLQA LYFCRPFREN VLAYKAQQKK 60
KENLLTCLAD LFHSIATQKK KVGVIPPKKF ISRLRKENDL FDNYMQQDAH EFLNYLLNTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCTTTTAG GGCACCAATG CCTCTGCTCT GGAAAAAGAC ATTGGTCCAG AGCAGTTTCC 60
GATCAATGAA CACTACTTTG GATTGGTCAA CGTAAGTATT TCAAAATGTA TTACTTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	59.34	7.00e-125	440.00
IUUC-Aml-002353	Ailuropoda melanoleuca	99.72	0.00e+00	696.00
IUUC-Atr-002650	Amborella trichopoda	59.45	2.00e-125	441.00
IUUC-Apl-003380	Anas platyrhynchos	98.59	0.00e+00	687.00
IUUC-Aca-005031	Anolis carolinensis	97.46	0.00e+00	728.00
IUUC-Aly-005830	Arabidopsis lyrata	58.54	9.00e-123	432.00
IUUC-Ath-007280	Arabidopsis thaliana	58.54	9.00e-123	432.00
IUUC-Ago-007871	Ashbya gossypii	38.57	6.00e-49	189.00
IUUC-Ame-010862	Astyanax mexicanus	94.96	0.00e+00	702.00
IUUC-Bta-013023	Bos taurus	99.72	0.00e+00	697.00
IUUC-Bdi-014008	Brachypodium distachyon	60.44	1.00e-124	439.00
IUUC-Bol-015138	Brassica oleracea	59.73	5.00e-124	437.00
IUUC-Bra-017483	Brassica rapa	60.23	9.00e-126	442.00
IUUC-Cel-018379	Caenorhabditis elegans	62.22	2.00e-144	505.00
IUUC-Cja-018956	Callithrix jacchus	99.72	0.00e+00	695.00
IUUC-Cfa-021064	Canis familiaris	99.15	0.00e+00	687.00
IUUC-Cpo-022443	Cavia porcellus	99.44	0.00e+00	693.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.52	3.00e-99	354.00
IUUC-Csa-023841	Chlorocebus sabaeus	99.72	0.00e+00	696.00
IUUC-Cne-026900	Cryptococcus neoformans	42.12	1.00e-60	227.00
IUUC-Dre-028230	Danio rerio	93.85	0.00e+00	698.00
IUUC-Dno-029209	Dasypus novemcinctus	99.72	0.00e+00	694.00
IUUC-Dme-032038	Drosophila melanogaster	81.28	4.00e-100	358.00
IUUC-Eeu-034916	Erinaceus europaeus	98.30	2.00e-161	561.00
IUUC-Fca-036299	Felis catus	99.72	0.00e+00	695.00
IUUC-Fox-037682	Fusarium oxysporum	42.32	1.00e-74	274.00
IUUC-Fso-038299	Fusarium solani	37.07	6.00e-75	275.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	693.00
IUUC-Ggr-039806	Gaeumannomyces graminis	42.24	1.00e-75	277.00
IUUC-Gga-041157	Gallus gallus	98.59	0.00e+00	688.00
IUUC-Gac-041764	Gasterosteus aculeatus	95.48	0.00e+00	697.00
IUUC-Gma-043828	Glycine max	60.55	3.00e-127	447.00
IUUC-Ggo-044659	Gorilla gorilla	99.72	0.00e+00	694.00
IUUC-Hsa-046156	Homo sapiens	99.72	0.00e+00	696.00
IUUC-Hvu-047692	Hordeum vulgare	58.74	5.00e-123	433.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	99.72	0.00e+00	696.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	1.00e-69	256.00
IUUC-Lch-049969	Latimeria chalumnae	96.61	0.00e+00	660.00
IUUC-Lpe-051368	Leersia perrieri	58.86	2.00e-122	431.00
IUUC-Loc-052479	Lepisosteus oculatus	90.96	0.00e+00	669.00
IUUC-Laf-054085	Loxodonta africana	99.72	0.00e+00	696.00
IUUC-Mcc-055566	Macaca mulatta	99.72	0.00e+00	696.00
IUUC-Mtr-057715	Medicago truncatula	60.55	1.00e-126	446.00
IUUC-Mla-059142	Melampsora laricipopulina	52.98	2.00e-94	340.00
IUUC-Mga-059575	Meleagris gallopavo	98.59	0.00e+00	686.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	7.00e-78	285.00
IUUC-Mdo-062579	Monodelphis domestica	99.44	0.00e+00	694.00
IUUC-Mmu-063611	Mus musculus	99.72	0.00e+00	696.00
IUUC-Mac-065323	Musa acuminata	60.56	2.00e-123	435.00
IUUC-Mpu-066038	Mustela putorius furo	99.72	0.00e+00	695.00
IUUC-Mlu-068183	Myotis lucifugus	99.44	0.00e+00	694.00
IUUC-Nle-069330	Nomascus leucogenys	99.72	0.00e+00	696.00
IUUC-Opr-070980	Ochotona princeps	99.44	0.00e+00	694.00
IUUC-Ont-072134	Oreochromis niloticus	95.24	0.00e+00	705.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.50	0.00e+00	684.00
IUUC-Ocu-074923	Oryctolagus cuniculus	99.44	0.00e+00	692.00
IUUC-Oba-075220	Oryza barthii	59.62	2.00e-122	431.00
IUUC-Obr-076208	Oryza brachyantha	57.42	2.00e-119	421.00
IUUC-Ogl-077216	Oryza glaberrima	59.62	2.00e-122	431.00
IUUC-Ogu-078836	Oryza glumaepatula	59.62	2.00e-122	431.00
IUUC-Oin-079522	Oryza indica	59.62	2.00e-122	431.00
IUUC-Olo-080882	Oryza longistaminata	59.62	2.00e-122	431.00
IUUC-Ome-081549	Oryza meridionalis	59.62	2.00e-122	431.00
IUUC-Oni-082982	Oryza nivara	59.62	2.00e-122	431.00
IUUC-Opu-083532	Oryza punctata	59.62	1.00e-122	432.00
IUUC-Oru-084568	Oryza rufipogon	59.62	2.00e-122	431.00
IUUC-Osa-085299	Oryza sativa	59.62	2.00e-122	431.00
IUUC-Ola-086546	Oryzias latipes	95.24	0.00e+00	703.00
IUUC-Olu-087809	Ostreococcus lucimarinus	47.88	1.00e-80	293.00
IUUC-Oga-088073	Otolemur garnettii	100.00	0.00e+00	698.00
IUUC-Oar-089248	Ovis aries	99.72	0.00e+00	696.00
IUUC-Ptr-090814	Pan troglodytes	99.72	0.00e+00	696.00
IUUC-Pan-091753	Papio anubis	99.72	0.00e+00	696.00
IUUC-Psi-094012	Pelodiscus sinensis	99.15	0.00e+00	689.00
IUUC-Pma-094388	Petromyzon marinus	89.75	0.00e+00	667.00
IUUC-Ppa-095415	Physcomitrella patens	59.29	2.00e-126	445.00
IUUC-Pfo-097369	Poecilia formosa	95.24	0.00e+00	705.00
IUUC-Pab-098594	Pongo abelii	99.72	0.00e+00	695.00
IUUC-Pop-099798	Populus trichocarpa	60.00	3.00e-126	444.00
IUUC-Pca-100913	Procavia capensis	83.62	1.00e-158	551.00
IUUC-Ppe-101474	Prunus persica	59.73	2.00e-126	444.00
IUUC-Pva-102892	Pteropus vampyrus	99.72	0.00e+00	695.00
IUUC-Rno-104909	Rattus norvegicus	99.44	0.00e+00	695.00
IUUC-Sce-106367	Saccharomyces cerevisiae	37.63	8.00e-56	211.00
IUUC-Sha-107400	Sarcophilus harrisii	99.44	0.00e+00	693.00
IUUC-Smo-109064	Selaginella moellendorffii	60.50	6.00e-121	426.00
IUUC-Sit-110819	Setaria italica	59.62	4.00e-123	434.00
IUUC-Sly-111210	Solanum lycopersicum	59.62	4.00e-126	444.00
IUUC-Stu-112398	Solanum tuberosum	60.06	3.00e-126	444.00
IUUC-Sbi-114562	Sorghum bicolor	58.79	2.00e-123	435.00
IUUC-Ssc-115550	Sus scrofa	99.72	0.00e+00	695.00
IUUC-Tgu-116800	Taeniopygia guttata	98.59	0.00e+00	688.00
IUUC-Tru-118212	Takifugu rubripes	94.96	0.00e+00	705.00
IUUC-Tni-120071	Tetraodon nigroviridis	94.96	0.00e+00	705.00
IUUC-Tca-121329	Theobroma cacao	60.00	1.00e-126	446.00
IUUC-Tae-124807	Triticum aestivum	59.34	2.00e-125	441.00
IUUC-Tur-126563	Triticum urartu	59.34	2.00e-125	441.00
IUUC-Tme-126890	Tuber melanosporum	46.78	3.00e-91	329.00
IUUC-Vpa-130590	Vicugna pacos	94.92	0.00e+00	648.00
IUUC-Vvi-131371	Vitis vinifera	60.00	7.00e-127	446.00
IUUC-Xma-133111	Xiphophorus maculatus	95.24	0.00e+00	705.00
IUUC-Yli-134632	Yarrowia lipolytica	44.86	4.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence