iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Post-translational Modifications (PTMs)
CPLM	dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-42	139.8	579	617
UBD/Beta-Prp	3.40e-77	259.6	542	698

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ +v cl+   d +l+v+Gs D ++kvW l  g++ +
   Q: 579  GHKLPVICLDIsYDsNLIVTGSADRNVKVWGLNFGDCHR 617
           799999**9999455********************9976 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           v+ c+++spd ++la+g  d+t+kv+ ++t k+  sl+gh+ +v ++++s d++++vtgs Dr++kvw l+ g+c +++ +h+dsv+s++f p ++ +
   Q: 542  VL-CLAVSPDMKYLAVGLLDATVKVFFLDTFKFYLSLYGHKLPVICLDISYDSNLIVTGSADRNVKVWGLNFGDCHRSIFAHDDSVMSVQFIPRTHMF 638
           44.5999******************************************************************************************* PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            + ++d  ++ wd ++ +++  tl gh g   c++v+p+g++lv+++ Drt+r++    ++
   Q: 639  FTCGKDGKVKQWDGDNFEKIL-TLPGHIGEAYCLSVSPNGRYLVTCGSDRTLRMFERTDET 698
           *********************.*********************************875554 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGLTKQYLAY RAIDSFNIIT SGRANVNFAV VDKTEGRYVA APAAENVIVW DLRMGDRKLT 60
LRREKFEVTS LRVSPDHLHI AVGYADGMVQ IFDLSSDRYY DPICTLALHK NAVSILRYDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAATCGATT GGGAACCATC TCCAAACACG TGAAACGCGA TTTTTGATTT ACCTTATGTG 60
TTTTGAATGC TGCAATGGGT TTAACTAAAC AATATTTGGC CTACCGGGCT ATAGACAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0009267--P:cellular response to starvation
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0022008--P:neurogenesis

KEGG

dme:Dmel_CG8064

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000784	Aegilops tauschii	32.95	9.00e-107	380.00
IUUC-Aml-001245	Ailuropoda melanoleuca	41.80	0.00e+00	665.00
IUUC-Atr-002700	Amborella trichopoda	32.00	1.00e-125	443.00
IUUC-Apl-004164	Anas platyrhynchos	44.74	7.00e-154	536.00
IUUC-Aca-004765	Anolis carolinensis	42.27	0.00e+00	690.00
IUUC-Aly-006503	Arabidopsis lyrata	34.01	2.00e-132	466.00
IUUC-Ath-006848	Arabidopsis thaliana	33.55	7.00e-134	470.00
IUUC-Ago-007909	Ashbya gossypii	31.56	3.00e-127	449.00
IUUC-Acl-008238	Aspergillus clavatus	31.83	6.00e-133	467.00
IUUC-Afl-008544	Aspergillus flavus	31.30	5.00e-126	444.00
IUUC-Afu-008868	Aspergillus fumigatus	33.01	6.00e-130	457.00
IUUC-Ani-009367	Aspergillus nidulans	31.13	1.00e-123	436.00
IUUC-Ang-009732	Aspergillus niger	32.81	2.00e-132	466.00
IUUC-Aor-010140	Aspergillus oryzae	31.37	1.00e-126	446.00
IUUC-Ate-010572	Aspergillus terreus	31.04	4.00e-127	448.00
IUUC-Ame-010956	Astyanax mexicanus	39.33	9.00e-178	616.00
IUUC-Bgr-012296	Blumeria graminis	30.91	3.00e-128	452.00
IUUC-Bta-012716	Bos taurus	42.08	0.00e+00	681.00
IUUC-Bci-013699	Botrytis cinerea	31.07	4.00e-121	428.00
IUUC-Bdi-014525	Brachypodium distachyon	31.88	5.00e-122	431.00
IUUC-Bol-015117	Brassica oleracea	35.11	7.00e-137	480.00
IUUC-Bra-016869	Brassica rapa	35.08	6.00e-137	481.00
IUUC-Cel-018570	Caenorhabditis elegans	31.79	5.00e-113	401.00
IUUC-Cja-019425	Callithrix jacchus	41.21	0.00e+00	681.00
IUUC-Cfa-020787	Canis familiaris	41.96	0.00e+00	665.00
IUUC-Cpo-021729	Cavia porcellus	42.99	1.00e-148	519.00
IUUC-Cre-022678	Chlamydomonas reinhardtii	37.77	1.00e-76	280.00
IUUC-Csa-024098	Chlorocebus sabaeus	42.39	0.00e+00	691.00
IUUC-Cho-024495	Choloepus hoffmanni	38.00	2.00e-103	369.00
IUUC-Cin-025245	Ciona intestinalis	35.84	2.00e-106	378.00
IUUC-Cgl-026708	Colletotrichum gloeosporioides	33.33	8.00e-129	454.00
IUUC-Cne-026835	Cryptococcus neoformans	37.19	3.00e-96	345.00
IUUC-Cme-027162	Cyanidioschyzon merolae	28.97	3.00e-30	126.00
IUUC-Dre-027874	Danio rerio	42.26	0.00e+00	697.00
IUUC-Dno-028905	Dasypus novemcinctus	41.64	0.00e+00	676.00
IUUC-Dor-030383	Dipodomys ordii	38.60	1.00e-86	313.00
IUUC-Dse-031297	Dothistroma septosporum	30.75	3.00e-123	435.00
IUUC-Ete-032608	Echinops telfairi	39.09	1.00e-110	392.00
IUUC-Eca-034181	Equus caballus	41.64	0.00e+00	668.00
IUUC-Eeu-034495	Erinaceus europaeus	42.32	0.00e+00	652.00
IUUC-Fca-035994	Felis catus	42.79	0.00e+00	640.00
IUUC-Fal-036611	Ficedula albicollis	41.71	0.00e+00	667.00
IUUC-Fox-037807	Fusarium oxysporum	32.04	5.00e-130	457.00
IUUC-Fso-038090	Fusarium solani	31.70	2.00e-127	449.00
IUUC-Gmo-039018	Gadus morhua	39.39	3.00e-101	362.00
IUUC-Ggr-039748	Gaeumannomyces graminis	32.74	9.00e-136	477.00
IUUC-Gga-040707	Gallus gallus	41.82	0.00e+00	653.00
IUUC-Gac-042334	Gasterosteus aculeatus	38.83	1.00e-97	349.00
IUUC-Gma-043860	Glycine max	34.25	1.00e-129	456.00
IUUC-Ggo-045334	Gorilla gorilla	41.96	0.00e+00	681.00
IUUC-Hsa-046996	Homo sapiens	42.28	0.00e+00	680.00
IUUC-Hvu-047381	Hordeum vulgare	29.26	2.00e-54	206.00
IUUC-Itr-047938	Ictidomys tridecemlineatus	42.37	0.00e+00	676.00
IUUC-Kpa-049185	Komagataella pastoris	29.96	2.00e-116	412.00
IUUC-Lch-050098	Latimeria chalumnae	38.82	3.00e-172	598.00
IUUC-Lpe-050710	Leersia perrieri	31.97	4.00e-114	405.00
IUUC-Loc-052745	Lepisosteus oculatus	40.80	0.00e+00	640.00
IUUC-Lma-053104	Leptosphaeria maculans	31.84	1.00e-131	464.00
IUUC-Laf-054395	Loxodonta africana	42.43	0.00e+00	681.00
IUUC-Mcc-055077	Macaca mulatta	42.28	0.00e+00	683.00
IUUC-Meu-056418	Macropus eugenii	44.12	2.00e-99	356.00
IUUC-Mor-057031	Magnaporthe oryzae	31.88	3.00e-116	412.00
IUUC-Mpo-057420	Magnaporthe poae	33.89	3.00e-132	465.00
IUUC-Mtr-057838	Medicago truncatula	34.66	9.00e-140	490.00
IUUC-Mla-058854	Melampsora laricipopulina	35.56	1.00e-98	353.00
IUUC-Mga-060120	Meleagris gallopavo	39.91	3.00e-175	608.00
IUUC-Mvi-060407	Microbotryum violaceum	36.91	2.00e-111	396.00
IUUC-Mmr-060635	Microcebus murinus	42.12	0.00e+00	676.00
IUUC-Mdo-063023	Monodelphis domestica	42.33	0.00e+00	682.00
IUUC-Mmu-064103	Mus musculus	42.55	0.00e+00	692.00
IUUC-Mac-065569	Musa acuminata	33.58	2.00e-131	462.00
IUUC-Mpu-066462	Mustela putorius furo	42.54	0.00e+00	677.00
IUUC-Mlu-067894	Myotis lucifugus	42.39	0.00e+00	680.00
IUUC-Nfi-068321	Neosartorya fischeri	32.21	5.00e-127	447.00
IUUC-Ncr-068661	Neurospora crassa	32.15	1.00e-127	449.00
IUUC-Nle-069409	Nomascus leucogenys	42.28	0.00e+00	688.00
IUUC-Opr-070445	Ochotona princeps	42.46	2.00e-125	442.00
IUUC-Ont-072339	Oreochromis niloticus	42.40	0.00e+00	679.00
IUUC-Oan-073688	Ornithorhynchus anatinus	40.77	0.00e+00	642.00
IUUC-Ocu-074227	Oryctolagus cuniculus	42.07	0.00e+00	686.00
IUUC-Oba-075635	Oryza barthii	32.32	2.00e-111	396.00
IUUC-Obr-076897	Oryza brachyantha	33.22	2.00e-121	429.00
IUUC-Ogl-077555	Oryza glaberrima	32.32	4.00e-111	395.00
IUUC-Ogu-078724	Oryza glumaepatula	32.32	5.00e-112	398.00
IUUC-Oin-080030	Oryza indica	32.44	6.00e-112	397.00
IUUC-Olo-080687	Oryza longistaminata	30.36	6.00e-99	354.00
IUUC-Ome-081867	Oryza meridionalis	32.01	1.00e-112	400.00
IUUC-Oni-082559	Oryza nivara	32.32	6.00e-111	394.00
IUUC-Opu-083332	Oryza punctata	34.46	7.00e-110	390.00
IUUC-Oru-084455	Oryza rufipogon	32.44	1.00e-111	397.00
IUUC-Osa-085793	Oryza sativa	32.44	1.00e-111	397.00
IUUC-Ola-087395	Oryzias latipes	41.19	5.00e-180	624.00
IUUC-Olu-087768	Ostreococcus lucimarinus	33.03	1.00e-116	413.00
IUUC-Oga-088574	Otolemur garnettii	42.28	0.00e+00	686.00
IUUC-Oar-089453	Ovis aries	41.98	0.00e+00	679.00
IUUC-Ptr-090694	Pan troglodytes	42.28	0.00e+00	678.00
IUUC-Pan-092420	Papio anubis	41.85	0.00e+00	683.00
IUUC-Psi-093683	Pelodiscus sinensis	41.49	0.00e+00	665.00
IUUC-Pma-094197	Petromyzon marinus	37.66	2.00e-35	141.00
IUUC-Pno-094783	Phaeosphaeria nodorum	31.35	2.00e-131	462.00
IUUC-Ppa-095208	Physcomitrella patens	33.69	1.00e-135	476.00
IUUC-Pfo-096299	Poecilia formosa	41.88	0.00e+00	694.00
IUUC-Pab-098706	Pongo abelii	42.32	0.00e+00	683.00
IUUC-Pop-099275	Populus trichocarpa	34.67	1.00e-127	449.00
IUUC-Pca-100796	Procavia capensis	35.75	1.00e-127	449.00
IUUC-Ppe-101861	Prunus persica	34.29	1.00e-129	456.00
IUUC-Pva-103241	Pteropus vampyrus	39.14	8.00e-172	597.00
IUUC-Pgr-103432	Puccinia graminis	45.66	7.00e-90	324.00
IUUC-Ptt-103742	Puccinia triticina	45.07	3.00e-86	312.00
IUUC-Pte-104069	Pyrenophora teres	32.28	4.00e-124	438.00
IUUC-Pyt-104650	Pyrenophora triticirepentis	31.86	4.00e-131	461.00
IUUC-Rno-105219	Rattus norvegicus	41.58	0.00e+00	664.00
IUUC-Sce-106271	Saccharomyces cerevisiae	32.31	2.00e-127	449.00
IUUC-Sha-107550	Sarcophilus harrisii	42.24	0.00e+00	681.00
IUUC-Sja-107664	Schizosaccharomyces japonicus	30.90	6.00e-119	421.00
IUUC-Spo-108239	Schizosaccharomyces pombe	31.85	2.00e-125	442.00
IUUC-Ssl-108626	Sclerotinia sclerotiorum	32.29	7.00e-130	457.00
IUUC-Smo-109477	Selaginella moellendorffii	32.64	2.00e-119	422.00
IUUC-Sit-110000	Setaria italica	32.98	8.00e-116	410.00
IUUC-Sly-111595	Solanum lycopersicum	33.37	7.00e-125	441.00
IUUC-Stu-112516	Solanum tuberosum	33.66	7.00e-126	444.00
IUUC-Sar-113195	Sorex araneus	41.39	9.00e-126	443.00
IUUC-Sbi-114465	Sorghum bicolor	32.27	3.00e-121	429.00
IUUC-Sre-115006	Sporisorium reilianum	30.66	5.00e-122	431.00
IUUC-Ssc-115929	Sus scrofa	41.76	0.00e+00	671.00
IUUC-Tgu-117282	Taeniopygia guttata	41.39	0.00e+00	665.00
IUUC-Tru-118406	Takifugu rubripes	41.93	0.00e+00	670.00
IUUC-Tsy-119170	Tarsius syrichta	41.87	0.00e+00	674.00
IUUC-Tni-119721	Tetraodon nigroviridis	41.89	0.00e+00	649.00
IUUC-Tca-121761	Theobroma cacao	34.54	2.00e-138	486.00
IUUC-Tre-121908	Trichoderma reesei	31.97	6.00e-126	444.00
IUUC-Tvi-122547	Trichoderma virens	31.79	4.00e-127	448.00
IUUC-Tae-125496	Triticum aestivum	32.67	4.00e-116	411.00
IUUC-Tur-126811	Triticum urartu	33.63	2.00e-117	416.00
IUUC-Tme-126987	Tuber melanosporum	33.93	5.00e-134	471.00
IUUC-Tbe-127315	Tupaia belangeri	45.13	9.00e-107	380.00
IUUC-Ttr-129165	Tursiops truncatus	36.95	4.00e-158	551.00
IUUC-Uma-129651	Ustilago maydis	30.41	4.00e-118	418.00
IUUC-Vda-129973	Verticillium dahliae	32.07	3.00e-123	435.00
IUUC-Vpa-130163	Vicugna pacos	35.21	9.00e-71	261.00
IUUC-Vvi-131402	Vitis vinifera	33.73	2.00e-128	452.00
IUUC-Xtr-132296	Xenopus tropicalis	39.94	0.00e+00	651.00
IUUC-Xma-133028	Xiphophorus maculatus	42.09	0.00e+00	697.00
IUUC-Yli-134484	Yarrowia lipolytica	31.53	8.00e-118	417.00
IUUC-Zma-135938	Zea mays	33.14	6.00e-119	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence