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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-106027
Ensembl Protein ID ENSRNOP00000055692.3
UniProt Accession D3ZCM7; D3ZCM7_RAT
Genbank Protein ID ENSRNOP00000055692
Protein Name Transducin-like enhancer of split 1
Genbank Nucleotide ID AABR07048697
Gene Name Tle1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000005882.7 ENSRNOT00000089560.1 ENSRNOP00000072474.1
ENSRNOG00000005882.7 ENSRNOT00000058906.3 ENSRNOP00000055692.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IIDHINT
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-21 76.0 614 652
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 614  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 652
           8***********999*********************998 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-106027|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCGTGCGCC GGCCTGCTGC GCTGCTTCGC GTTCCTCGGT GGAATTCAAG TTGGAAGTGG 60
CGCGGAGGAT AGAGCTATCC CGGAACAGAG CCGCGGCTGC TGCCAGAGCG ATGTTCCCTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-106027|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF03920--TLE_N
PF00400--WD40
PRINTS

PR01850--GROUCHOFAMLY
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression
KEGG rno:362533
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001746 Ailuropoda melanoleuca 93.55 0.00e+00 1253.00
IUUC-Apl-003594 Anas platyrhynchos 93.32 0.00e+00 1233.00
IUUC-Aca-005053 Anolis carolinensis 92.07 0.00e+00 1267.00
IUUC-Bta-013380 Bos taurus 88.36 0.00e+00 1137.00
IUUC-Cja-019135 Callithrix jacchus 96.89 0.00e+00 1292.00
IUUC-Cfa-020611 Canis familiaris 96.65 0.00e+00 1174.00
IUUC-Cpo-022495 Cavia porcellus 96.89 0.00e+00 1293.00
IUUC-Csa-024056 Chlorocebus sabaeus 96.76 0.00e+00 1306.00
IUUC-Cin-025767 Ciona intestinalis 58.00 6.00e-170 591.00
IUUC-Dno-029011 Dasypus novemcinctus 96.25 0.00e+00 1286.00
IUUC-Ete-032533 Echinops telfairi 85.49 0.00e+00 1177.00
IUUC-Eca-033351 Equus caballus 97.15 0.00e+00 1295.00
IUUC-Eeu-034666 Erinaceus europaeus 96.37 0.00e+00 1058.00
IUUC-Fal-036696 Ficedula albicollis 95.53 0.00e+00 1236.00
IUUC-Gmo-038805 Gadus morhua 82.06 0.00e+00 1157.00
IUUC-Gga-041113 Gallus gallus 95.85 0.00e+00 1337.00
IUUC-Gac-041999 Gasterosteus aculeatus 81.67 0.00e+00 1164.00
IUUC-Ggo-045164 Gorilla gorilla 96.89 0.00e+00 1308.00
IUUC-Hsa-047011 Homo sapiens 96.89 0.00e+00 1308.00
IUUC-Itr-048040 Ictidomys tridecemlineatus 92.80 0.00e+00 1256.00
IUUC-Lch-050437 Latimeria chalumnae 92.39 0.00e+00 1105.00
IUUC-Loc-052819 Lepisosteus oculatus 89.27 0.00e+00 1212.00
IUUC-Laf-053862 Loxodonta africana 93.86 0.00e+00 1251.00
IUUC-Mcc-055735 Macaca mulatta 92.80 0.00e+00 1291.00
IUUC-Mmr-061207 Microcebus murinus 93.48 0.00e+00 1247.00
IUUC-Mdo-062493 Monodelphis domestica 96.50 0.00e+00 1344.00
IUUC-Mmu-063795 Mus musculus 96.92 0.00e+00 1296.00
IUUC-Mpu-065819 Mustela putorius furo 97.54 0.00e+00 1323.00
IUUC-Mlu-067047 Myotis lucifugus 96.76 0.00e+00 1278.00
IUUC-Nle-069684 Nomascus leucogenys 96.63 0.00e+00 1298.00
IUUC-Opr-071172 Ochotona princeps 96.24 0.00e+00 1274.00
IUUC-Ont-072102 Oreochromis niloticus 82.14 0.00e+00 1176.00
IUUC-Ocu-074592 Oryctolagus cuniculus 94.19 0.00e+00 1299.00
IUUC-Ola-087267 Oryzias latipes 79.85 0.00e+00 1089.00
IUUC-Oga-088629 Otolemur garnettii 94.12 0.00e+00 1252.00
IUUC-Oar-089551 Ovis aries 95.73 0.00e+00 1271.00
IUUC-Ptr-091207 Pan troglodytes 96.50 0.00e+00 1301.00
IUUC-Pan-091822 Papio anubis 92.80 0.00e+00 1291.00
IUUC-Psi-093594 Pelodiscus sinensis 94.59 0.00e+00 1259.00
IUUC-Pfo-096239 Poecilia formosa 81.57 0.00e+00 1164.00
IUUC-Pab-097687 Pongo abelii 96.86 0.00e+00 1290.00
IUUC-Pva-102355 Pteropus vampyrus 92.49 0.00e+00 1192.00
IUUC-Sha-107419 Sarcophilus harrisii 91.57 0.00e+00 1263.00
IUUC-Sar-113585 Sorex araneus 84.89 0.00e+00 707.00
IUUC-Ssc-116151 Sus scrofa 96.63 0.00e+00 1288.00
IUUC-Tgu-117387 Taeniopygia guttata 95.08 0.00e+00 1313.00
IUUC-Tru-118051 Takifugu rubripes 78.05 0.00e+00 1113.00
IUUC-Tsy-119342 Tarsius syrichta 89.34 0.00e+00 1003.00
IUUC-Tbe-127881 Tupaia belangeri 94.04 0.00e+00 1273.00
IUUC-Xtr-131792 Xenopus tropicalis 87.28 0.00e+00 1217.00
Created Date 25-Jun-2017

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