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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063999
UUCD1 version UUC-MuM-00795
Ensembl Protein ID ENSMUSP00000044637.4
UniProt Accession Q9CQ31; A2AIH7; Q3UJ13; Q9D0V1; ASB11_MOUSE
Genbank Protein ID AAK97494.1; BAB22080.1; BAB23286.1; BAB24004.1; BAE27342.1; CAM17374.1; AAH64047.1
Protein Name Ankyrin repeat and SOCS box protein 11
Genbank Nucleotide ID AF398972; AK002412; AK004396; AK005404; AK146664; AL732475; BC064047
Gene Name Asb11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000031382.14 ENSMUST00000036858.10 ENSMUSP00000044637.4
ENSMUSG00000031382.14 ENSMUST00000033755.5 ENSMUSP00000033755.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 90.71 8.00e-157 550.00 IUUC-Hsa-046101
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Sequence
(Fasta)
MEDAPAFYGF KNIFLTMFAT FFFFKLLIKV FLALLTHFYI VKGNRKEAAR IAEEIYGGLS 60
DCWADRSPLH EAAAQGRLLA LKTLIAQGIN VNLVTINRVS SLHEACLGGH VACAKALLEN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063999|E3,SOCS|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AACTCAGTAA AAATTTGCAG CCGTAGGAAC CTGTGCCGAG AAGAAGCCAA AATGGAAGAT 60
GCTCCTGCTT TCTATGGCTT TAAAAACATT TTTCTTACAA TGTTTGCAAC GTTTTTTTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063999|E3,SOCS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001496--SOCS_box
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50225--SOCS
Pfam

PF00023--Ank
PF12796--Ank_2
PF07525--SOCS_box
SMART

SM00248--ANK
SM00969--SOCS_box
Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination
KEGG mmu:68854
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001489 Ailuropoda melanoleuca 87.66 8.00e-149 519.00
IUUC-Apl-003530 Anas platyrhynchos 72.45 3.00e-132 464.00
IUUC-Ame-010976 Astyanax mexicanus 36.45 2.00e-42 166.00
IUUC-Bta-012746 Bos taurus 86.07 6.00e-150 523.00
IUUC-Cja-019292 Callithrix jacchus 89.78 3.00e-157 547.00
IUUC-Cfa-020069 Canis familiaris 88.96 1.00e-151 529.00
IUUC-Cpo-022164 Cavia porcellus 89.16 4.00e-157 546.00
IUUC-Csa-023539 Chlorocebus sabaeus 91.88 7.00e-153 533.00
IUUC-Cho-024465 Choloepus hoffmanni 71.99 3.00e-108 384.00
IUUC-Dre-028590 Danio rerio 50.00 4.00e-86 311.00
IUUC-Dno-028948 Dasypus novemcinctus 87.93 9.00e-153 532.00
IUUC-Dor-030607 Dipodomys ordii 69.66 8.00e-108 383.00
IUUC-Ete-032897 Echinops telfairi 88.64 8.00e-146 509.00
IUUC-Eca-034213 Equus caballus 90.40 2.00e-157 548.00
IUUC-Eeu-034684 Erinaceus europaeus 75.53 2.00e-103 368.00
IUUC-Fca-036195 Felis catus 82.74 2.00e-145 508.00
IUUC-Fal-037341 Ficedula albicollis 54.77 2.00e-100 359.00
IUUC-Gga-040371 Gallus gallus 71.21 2.00e-130 458.00
IUUC-Ggo-045195 Gorilla gorilla 90.40 2.00e-158 551.00
IUUC-Hsa-046101 Homo sapiens 90.71 2.00e-158 551.00
IUUC-Itr-048473 Ictidomys tridecemlineatus 91.21 4.00e-155 540.00
IUUC-Lch-049957 Latimeria chalumnae 73.05 2.00e-117 415.00
IUUC-Loc-051897 Lepisosteus oculatus 65.63 1.00e-124 439.00
IUUC-Laf-053995 Loxodonta africana 86.69 7.00e-151 526.00
IUUC-Mcc-055105 Macaca mulatta 91.56 1.00e-151 528.00
IUUC-Mga-060110 Meleagris gallopavo 70.95 2.00e-127 448.00
IUUC-Mmr-060790 Microcebus murinus 86.02 5.00e-145 506.00
IUUC-Mdo-063038 Monodelphis domestica 79.26 3.00e-141 494.00
IUUC-Mpu-065750 Mustela putorius furo 87.01 1.00e-147 515.00
IUUC-Mlu-067133 Myotis lucifugus 87.31 1.00e-157 548.00
IUUC-Nle-069508 Nomascus leucogenys 91.23 8.00e-152 529.00
IUUC-Opr-070897 Ochotona princeps 65.65 2.00e-92 332.00
IUUC-Oan-072705 Ornithorhynchus anatinus 55.00 4.00e-75 274.00
IUUC-Ocu-074144 Oryctolagus cuniculus 91.56 3.00e-152 531.00
IUUC-Ola-086779 Oryzias latipes 51.41 3.00e-87 315.00
IUUC-Oga-088306 Otolemur garnettii 88.92 1.00e-153 535.00
IUUC-Oar-089814 Ovis aries 86.69 1.00e-150 525.00
IUUC-Pan-092867 Papio anubis 91.56 2.00e-152 531.00
IUUC-Psi-094054 Pelodiscus sinensis 73.99 2.00e-136 478.00
IUUC-Pma-094342 Petromyzon marinus 49.81 1.00e-64 239.00
IUUC-Pfo-097132 Poecilia formosa 50.92 9.00e-92 330.00
IUUC-Pab-097685 Pongo abelii 90.40 1.00e-157 548.00
IUUC-Pva-102949 Pteropus vampyrus 86.38 2.00e-149 521.00
IUUC-Sha-107348 Sarcophilus harrisii 81.11 3.00e-144 504.00
IUUC-Sar-113203 Sorex araneus 61.92 6.00e-94 337.00
IUUC-Ssc-116245 Sus scrofa 87.31 1.00e-151 528.00
IUUC-Tgu-117317 Taeniopygia guttata 71.83 2.00e-131 461.00
IUUC-Tsy-118847 Tarsius syrichta 69.04 5.00e-106 377.00
IUUC-Tni-120408 Tetraodon nigroviridis 55.31 3.00e-82 298.00
IUUC-Tme-127223 Tuber melanosporum 31.08 8.00e-07 48.10
IUUC-Tbe-127290 Tupaia belangeri 77.09 3.00e-129 454.00
IUUC-Ttr-128755 Tursiops truncatus 87.00 6.00e-152 530.00
IUUC-Vpa-130064 Vicugna pacos 78.33 9.00e-133 466.00
IUUC-Xtr-132081 Xenopus tropicalis 63.78 2.00e-115 408.00
Created Date 25-Jun-2017

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