iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072406

Ensembl Protein ID

ENSONIP00000026688.1

UniProt Accession

I3KZZ1; I3KZZ1_ORENI

Genbank Protein ID

AKK23721.1

Protein Name

Suppressor of cytokine signaling 3

Genbank Nucleotide ID

AERX01023626

Gene Name

socs3a; socs3; SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000021386.1	ENSONIT00000026712.1	ENSONIP00000026688.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	55.02	4.00e-67	251.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MVTHSKFDSA MSSSPLDSKM RLSYHYKTFT SKTQYQMVLS TFQKLQESGF YWSTITGKEA 60
NAMLASEKVG TFLIRDSADH RHLFTLSVKT ASGTKNLRIQ YDSNSFYLQT DPKNVQSVPH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAACTC ACAGCAAGTT TGACTCCGCG ATGAGTAGCA GCCCCTTGGA CTCCAAAATG 60
CGGCTGTCTT ACCATTACAA AACTTTCACC TCGAAAACTC AGTATCAGAT GGTCCTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	52.84	2.00e-64	238.00
IUUC-Apl-003607	Anas platyrhynchos	63.41	5.00e-67	246.00
IUUC-Aca-005063	Anolis carolinensis	58.60	8.00e-67	246.00
IUUC-Ame-010859	Astyanax mexicanus	57.59	1.00e-75	275.00
IUUC-Bta-012817	Bos taurus	54.94	1.00e-67	249.00
IUUC-Cja-019605	Callithrix jacchus	54.59	4.00e-67	247.00
IUUC-Cfa-021231	Canis familiaris	54.15	2.00e-66	245.00
IUUC-Cpo-022003	Cavia porcellus	53.88	4.00e-66	244.00
IUUC-Csa-023511	Chlorocebus sabaeus	54.15	1.00e-66	245.00
IUUC-Dre-028536	Danio rerio	66.19	2.00e-83	301.00
IUUC-Dno-029003	Dasypus novemcinctus	55.90	4.00e-69	254.00
IUUC-Eca-034205	Equus caballus	46.93	2.00e-39	155.00
IUUC-Fca-036317	Felis catus	51.97	9.00e-64	236.00
IUUC-Gmo-038777	Gadus morhua	52.71	5.00e-36	143.00
IUUC-Gga-041258	Gallus gallus	61.03	5.00e-65	240.00
IUUC-Gac-041837	Gasterosteus aculeatus	76.10	2.00e-86	311.00
IUUC-Ggo-045620	Gorilla gorilla	54.15	1.00e-66	245.00
IUUC-Hsa-046909	Homo sapiens	54.15	1.00e-66	245.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	52.94	1.00e-66	246.00
IUUC-Lch-049510	Latimeria chalumnae	63.77	2.00e-73	268.00
IUUC-Loc-052863	Lepisosteus oculatus	73.68	1.00e-88	318.00
IUUC-Laf-054136	Loxodonta africana	53.88	3.00e-66	244.00
IUUC-Mcc-055383	Macaca mulatta	54.15	1.00e-66	245.00
IUUC-Meu-056153	Macropus eugenii	53.04	8.00e-66	243.00
IUUC-Mmr-061185	Microcebus murinus	53.91	2.00e-66	245.00
IUUC-Mdo-061819	Monodelphis domestica	53.28	6.00e-66	243.00
IUUC-Mmu-064231	Mus musculus	55.02	7.00e-68	249.00
IUUC-Mpu-066691	Mustela putorius furo	54.15	2.00e-66	245.00
IUUC-Mlu-067673	Myotis lucifugus	55.22	3.00e-68	251.00
IUUC-Oan-073249	Ornithorhynchus anatinus	57.07	1.00e-63	235.00
IUUC-Ola-087373	Oryzias latipes	50.27	1.00e-54	206.00
IUUC-Oga-088041	Otolemur garnettii	54.39	1.00e-66	246.00
IUUC-Oar-089646	Ovis aries	52.36	1.00e-63	236.00
IUUC-Ptr-091502	Pan troglodytes	54.15	1.00e-66	245.00
IUUC-Pan-091934	Papio anubis	54.15	1.00e-66	245.00
IUUC-Pfo-096412	Poecilia formosa	51.74	1.00e-56	212.00
IUUC-Pab-098554	Pongo abelii	54.15	1.00e-66	245.00
IUUC-Rno-105874	Rattus norvegicus	55.02	8.00e-68	249.00
IUUC-Sha-107151	Sarcophilus harrisii	52.59	1.00e-65	242.00
IUUC-Ssc-115722	Sus scrofa	51.18	3.00e-39	154.00
IUUC-Tgu-117151	Taeniopygia guttata	61.03	4.00e-64	237.00
IUUC-Tru-118428	Takifugu rubripes	73.66	3.00e-91	327.00
IUUC-Tni-120590	Tetraodon nigroviridis	76.10	1.00e-92	332.00
IUUC-Ttr-129065	Tursiops truncatus	53.65	4.00e-66	244.00
IUUC-Xtr-132167	Xenopus tropicalis	58.05	3.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence