iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000013864.1	ENSORLT00000017386.1	ENSORLP00000017385.1
ENSORLG00000013864.1	ENSORLT00000017390.1	ENSORLP00000017389.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.80e-21	74.6	594	950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           G++ + N+CY++S+L cL++++++ + +l + ++k++ e + e+++ l +++ + ++     + +k+++ r++l+++++++    ++e+
   Q: 594  GIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPQSKTDVEYYRETQELLRTEIVNPLRIHGyVCATKVMKLRRILEKVEAASGF--TSEE 680
           999***************************99999999999999999999999999877679***************988875..899* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk.sqik...clecdnvs.sreepfldls 173
           +D +Efl +l++++ +       k ++  ++ +++   ++  +kk+k +  +i++l+++++  s++k    ++c  ++  r+ + +++ 
   Q: 681  KDPEEFLIILFHHILRVD--PLLKLRSAGQKVQDCYFYQIFMDKKDKVGVPTIQQLLEWSFInSDLKfaeAPSCLIIQmPRFGKDFKMF 767
           **************9977..778889999999999*************************9843444334899****999********* PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPe....vLilhLkRfsfseeqksrekinkkvefpl 257
            ++  + e    +++d+Le+  +e++++g  + y+c+ c+++ + +   k+k+++e      +lh kR           + + k+++p+
   Q: 768  NKIFPSLEL---DITDLLEDTPRECRICGGLAfYECRDCYDDGDITAG-KIKQFCEkcntQVHLHPKRK---------AHRHGKLSVPK 843
           **9999988...*****************999899*****99985544.67777765545788888888.........23356788997 PP
   S: 258  eLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk..WllfdD.............skVtevke.eevleetg... 327
           eL+    + ++      +++ eL+av++ +      HYva+vk  + +  Wl fd               +V++++e e+ l+++    
   Q: 844  ELQEG--TGRQGGFP--RQRMELFAVLCIET----SHYVAFVKYGTADsaWLFFDSmadrdggqngfniPQVSPCPEvETYLKMSPeel 924
           76654..55544554..9**********999....9********555556888888888888888888877777765466666555777 PP
   S: 328  ................staYvlfYkr 337
                           ++aY+++Y++
   Q: 925  htldpksiqgqarrllCDAYMCMYQS 950
           7777888888888***********95 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MSSALWNQDR SGGGFREDWR FYMVIKECTV EKPAQKTLRI PRGSLGQACQ ERNSLGRTLP 60
PCKGKKSLRI LDQTNVVLSL DERDVLELEE KLAELLFPIT NCEERYALLC DEQRLQRVRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTCTG CCCTGTGGAA CCAGGATAGG TCTGGTGGGG GCTTCAGGGA GGACTGGCGC 60
TTCTACATGG TCATAAAAGA ATGTACTGTG GAGAAGCCTG CACAGAAGAC CCTAAGGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF01302--CAP_GLY
PF00443--UCH

SMART

SM01052--CAP_GLY

Gene Ontology

GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:1990108--P:protein linear deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ola:101156964

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001298	Ailuropoda melanoleuca	68.29	0.00e+00	1295.00
IUUC-Apl-003356	Anas platyrhynchos	68.85	0.00e+00	1276.00
IUUC-Aca-004402	Anolis carolinensis	63.44	0.00e+00	1131.00
IUUC-Ame-011581	Astyanax mexicanus	85.34	0.00e+00	1529.00
IUUC-Bta-012359	Bos taurus	68.19	0.00e+00	1292.00
IUUC-Cel-018528	Caenorhabditis elegans	31.71	3.00e-57	217.00
IUUC-Cja-018797	Callithrix jacchus	68.19	0.00e+00	1285.00
IUUC-Cfa-020264	Canis familiaris	68.09	0.00e+00	1292.00
IUUC-Cpo-022057	Cavia porcellus	68.29	0.00e+00	1294.00
IUUC-Csa-023093	Chlorocebus sabaeus	68.50	0.00e+00	1291.00
IUUC-Cho-024486	Choloepus hoffmanni	75.16	3.00e-134	472.00
IUUC-Cin-025179	Ciona intestinalis	44.74	1.00e-119	422.00
IUUC-Dre-028233	Danio rerio	83.72	0.00e+00	1533.00
IUUC-Dno-029496	Dasypus novemcinctus	68.33	0.00e+00	1291.00
IUUC-Dor-030919	Dipodomys ordii	82.07	0.00e+00	822.00
IUUC-Dme-032159	Drosophila melanogaster	47.14	2.00e-124	439.00
IUUC-Ete-032734	Echinops telfairi	64.18	0.00e+00	1187.00
IUUC-Eca-033350	Equus caballus	68.09	0.00e+00	1295.00
IUUC-Eeu-034566	Erinaceus europaeus	78.49	1.00e-86	314.00
IUUC-Fca-035632	Felis catus	62.39	0.00e+00	813.00
IUUC-Fal-037313	Ficedula albicollis	65.07	0.00e+00	1179.00
IUUC-Gmo-039239	Gadus morhua	88.43	0.00e+00	1576.00
IUUC-Gga-040668	Gallus gallus	68.36	0.00e+00	1271.00
IUUC-Gac-042630	Gasterosteus aculeatus	91.33	0.00e+00	1608.00
IUUC-Ggo-044462	Gorilla gorilla	68.08	0.00e+00	1281.00
IUUC-Hsa-045846	Homo sapiens	68.08	0.00e+00	1281.00
IUUC-Itr-048894	Ictidomys tridecemlineatus	69.04	4.00e-171	593.00
IUUC-Lch-050303	Latimeria chalumnae	65.13	0.00e+00	1144.00
IUUC-Loc-052190	Lepisosteus oculatus	80.44	0.00e+00	1464.00
IUUC-Laf-054480	Loxodonta africana	77.69	0.00e+00	635.00
IUUC-Mcc-055849	Macaca mulatta	68.29	0.00e+00	1287.00
IUUC-Meu-056755	Macropus eugenii	55.80	2.00e-152	533.00
IUUC-Mga-059561	Meleagris gallopavo	67.74	0.00e+00	1258.00
IUUC-Mmr-060942	Microcebus murinus	67.98	0.00e+00	1278.00
IUUC-Mdo-062618	Monodelphis domestica	67.67	0.00e+00	1284.00
IUUC-Mmu-063843	Mus musculus	67.67	0.00e+00	1238.00
IUUC-Mpu-066919	Mustela putorius furo	68.40	0.00e+00	1298.00
IUUC-Mlu-066983	Myotis lucifugus	67.26	0.00e+00	1271.00
IUUC-Nle-069893	Nomascus leucogenys	68.19	0.00e+00	1283.00
IUUC-Opr-071181	Ochotona princeps	60.88	0.00e+00	1030.00
IUUC-Ont-071697	Oreochromis niloticus	92.16	0.00e+00	1605.00
IUUC-Oan-073658	Ornithorhynchus anatinus	68.12	0.00e+00	1278.00
IUUC-Ocu-074954	Oryctolagus cuniculus	68.08	0.00e+00	1287.00
IUUC-Oga-089003	Otolemur garnettii	68.19	0.00e+00	1295.00
IUUC-Oar-090376	Ovis aries	67.91	0.00e+00	1292.00
IUUC-Ptr-090520	Pan troglodytes	66.42	0.00e+00	1236.00
IUUC-Pan-092281	Papio anubis	68.50	0.00e+00	1291.00
IUUC-Psi-093047	Pelodiscus sinensis	71.04	0.00e+00	1232.00
IUUC-Pma-094575	Petromyzon marinus	56.22	9.00e-67	246.00
IUUC-Pfo-096358	Poecilia formosa	89.03	0.00e+00	1489.00
IUUC-Pab-097740	Pongo abelii	68.19	0.00e+00	1284.00
IUUC-Pca-100461	Procavia capensis	60.88	0.00e+00	993.00
IUUC-Pva-102134	Pteropus vampyrus	61.66	0.00e+00	1133.00
IUUC-Rno-105807	Rattus norvegicus	67.57	0.00e+00	1221.00
IUUC-Sha-107236	Sarcophilus harrisii	67.76	0.00e+00	1236.00
IUUC-Sar-113366	Sorex araneus	82.67	0.00e+00	787.00
IUUC-Tgu-117201	Taeniopygia guttata	65.60	0.00e+00	1196.00
IUUC-Tru-117953	Takifugu rubripes	90.60	0.00e+00	1591.00
IUUC-Tsy-119610	Tarsius syrichta	66.22	0.00e+00	1246.00
IUUC-Tbe-128155	Tupaia belangeri	57.80	3.00e-153	535.00
IUUC-Ttr-128942	Tursiops truncatus	63.42	0.00e+00	1178.00
IUUC-Vpa-130281	Vicugna pacos	60.17	0.00e+00	1088.00
IUUC-Xtr-132627	Xenopus tropicalis	62.11	0.00e+00	1075.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence