iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089932

Ensembl Protein ID

ENSOARP00000017032.1

UniProt Accession

W5Q2U4; W5Q2U4_SHEEP

Genbank Protein ID

ENSOARP00000017032

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01080141

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000015864.1	ENSOART00000017273.1	ENSOARP00000017032.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.40e-15	55.0	153	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ ++LqhLCRl+I++c+ +     i++LPLP +LkdYL+++++q
   Q: 153  TKPLYTSAPPLQHLCRLTINKCTST-----IWGLPLPTRLKDYLEEYKFQ 197
           678999*******************.....8***************9886 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MTLRCLESSG NGAEGAQSQW GTAGSAEEPS PEAARLAKAL RELSHTGWYW GNMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGC GGTGCCTCGA GTCCTCCGGG AATGGCGCGG AAGGGGCGCA GAGCCAGTGG 60
GGGACCGCGG GGTCGGCGGA GGAGCCGTCC CCAGAGGCGG CGCGTCTGGC GAAGGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

KEGG

oas:101115017

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	96.46	2.00e-105	374.00
IUUC-Apl-003484	Anas platyrhynchos	79.08	5.00e-72	262.00
IUUC-Aca-004253	Anolis carolinensis	71.95	6.00e-72	263.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	2.20e-02	33.10
IUUC-Ame-011267	Astyanax mexicanus	62.28	3.00e-59	220.00
IUUC-Bta-013183	Bos taurus	98.99	5.00e-104	369.00
IUUC-Bra-017915	Brassica rapa	33.90	4.20e-02	32.30
IUUC-Cja-018862	Callithrix jacchus	94.44	2.00e-98	351.00
IUUC-Cfa-020226	Canis familiaris	96.45	2.00e-98	350.00
IUUC-Cpo-022414	Cavia porcellus	94.44	4.00e-103	366.00
IUUC-Csa-023758	Chlorocebus sabaeus	93.94	2.00e-102	364.00
IUUC-Cho-024471	Choloepus hoffmanni	86.84	3.00e-72	263.00
IUUC-Dre-028288	Danio rerio	55.96	4.00e-63	233.00
IUUC-Dno-029036	Dasypus novemcinctus	94.95	3.00e-104	370.00
IUUC-Dor-030447	Dipodomys ordii	97.35	2.00e-86	310.00
IUUC-Ete-033023	Echinops telfairi	91.92	1.00e-107	382.00
IUUC-Fca-036469	Felis catus	97.47	1.00e-101	362.00
IUUC-Fal-036642	Ficedula albicollis	74.07	7.00e-71	259.00
IUUC-Gmo-039331	Gadus morhua	60.58	4.00e-35	139.00
IUUC-Gga-040809	Gallus gallus	77.36	3.00e-73	266.00
IUUC-Gac-041398	Gasterosteus aculeatus	55.22	3.00e-60	224.00
IUUC-Ggo-045341	Gorilla gorilla	94.95	1.00e-98	351.00
IUUC-Hsa-046557	Homo sapiens	94.44	5.00e-111	392.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	80.77	4.00e-91	326.00
IUUC-Lch-050160	Latimeria chalumnae	62.42	1.00e-50	191.00
IUUC-Loc-051825	Lepisosteus oculatus	55.73	1.00e-60	225.00
IUUC-Laf-053560	Loxodonta africana	93.43	7.00e-96	342.00
IUUC-Mcc-055890	Macaca mulatta	93.94	2.00e-97	347.00
IUUC-Meu-056218	Macropus eugenii	79.80	9.00e-96	342.00
IUUC-Mga-059755	Meleagris gallopavo	69.95	1.00e-71	262.00
IUUC-Mmr-061387	Microcebus murinus	96.46	4.00e-105	373.00
IUUC-Mdo-062383	Monodelphis domestica	81.31	1.00e-95	342.00
IUUC-Mmu-063443	Mus musculus	92.42	1.00e-99	355.00
IUUC-Mpu-066459	Mustela putorius furo	95.96	9.00e-100	355.00
IUUC-Mlu-068040	Myotis lucifugus	95.45	3.00e-105	373.00
IUUC-Nle-069016	Nomascus leucogenys	90.40	2.00e-96	344.00
IUUC-Opr-071087	Ochotona princeps	88.38	5.00e-103	366.00
IUUC-Ont-072340	Oreochromis niloticus	54.15	3.00e-59	220.00
IUUC-Oan-073443	Ornithorhynchus anatinus	79.80	2.00e-91	327.00
IUUC-Ocu-074539	Oryctolagus cuniculus	94.42	2.00e-98	351.00
IUUC-Ola-087004	Oryzias latipes	60.13	2.00e-55	207.00
IUUC-Oga-088438	Otolemur garnettii	94.95	1.00e-103	368.00
IUUC-Ptr-091037	Pan troglodytes	94.95	1.00e-98	351.00
IUUC-Pan-092767	Papio anubis	94.95	2.00e-98	351.00
IUUC-Psi-093099	Pelodiscus sinensis	77.99	1.00e-74	271.00
IUUC-Pma-094671	Petromyzon marinus	45.51	4.00e-36	144.00
IUUC-Pfo-097073	Poecilia formosa	50.00	4.00e-55	207.00
IUUC-Pab-098319	Pongo abelii	94.44	1.00e-103	368.00
IUUC-Pca-101117	Procavia capensis	92.93	2.00e-99	353.00
IUUC-Pva-102117	Pteropus vampyrus	94.95	3.00e-97	347.00
IUUC-Rno-105913	Rattus norvegicus	91.92	4.00e-99	353.00
IUUC-Sha-106500	Sarcophilus harrisii	81.22	2.00e-94	337.00
IUUC-Ssc-115252	Sus scrofa	97.47	8.00e-107	379.00
IUUC-Tgu-117524	Taeniopygia guttata	76.10	2.00e-70	257.00
IUUC-Tsy-119335	Tarsius syrichta	93.38	3.00e-84	303.00
IUUC-Tni-120263	Tetraodon nigroviridis	53.72	4.00e-56	210.00
IUUC-Tca-121866	Theobroma cacao	39.02	2.10e-01	30.00
IUUC-Tbe-127915	Tupaia belangeri	95.96	4.00e-98	350.00
IUUC-Ttr-128372	Tursiops truncatus	96.97	3.00e-106	377.00
IUUC-Vpa-130422	Vicugna pacos	98.68	1.00e-87	315.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence