iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052856

Ensembl Protein ID

ENSLOCP00000001555.1

UniProt Accession

W5LZJ8; W5LZJ8_LEPOC

Genbank Protein ID

ENSLOCP00000001555

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01011256

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000001367.1	ENSLOCT00000001560.1	ENSLOCP00000001555.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-26	89.8	346	376
E3 adaptor/Cullin RING/APC_C/CDC20	3.10e-150	499.7	210	514

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 346  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 376
           8**********98889**************9 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 210  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 298
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           ++tl+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss  P+++++
   Q: 299  LSTLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSVIPVQQYT 387
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 388  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 476
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 477  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 514
           *********************************99875 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSCVARCKKA EIMSQNARKR FEVGLLSSSS LPRMDQDYER RLLRQINIQN ENASPIKAPE 60
VMRTLTPTNS PMSSPSKHGD RFIPSRAGAN WSINFHRINE NEKSPSQNRK TKDATSDTSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTGCG TTGCACGTTG CAAAAAAGCC GAAATTATGT CTCAGAACGC CAGGTGAGAA 60
GACCTTCAGA AAAACAATAT CTCGAATACT TGAGCATTTC ACCCTTAAGA GTCCGTCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	64.84	1.00e-115	409.00
IUUC-Aml-002003	Ailuropoda melanoleuca	90.76	0.00e+00	913.00
IUUC-Atr-002753	Amborella trichopoda	57.85	8.00e-134	470.00
IUUC-Apl-003212	Anas platyrhynchos	95.56	0.00e+00	972.00
IUUC-Aly-005442	Arabidopsis lyrata	56.29	3.00e-140	491.00
IUUC-Ath-006938	Arabidopsis thaliana	57.89	2.00e-138	485.00
IUUC-Ago-007784	Ashbya gossypii	42.70	2.00e-97	349.00
IUUC-Acl-008269	Aspergillus clavatus	49.39	2.00e-134	472.00
IUUC-Afl-008432	Aspergillus flavus	50.41	1.00e-134	473.00
IUUC-Afu-008829	Aspergillus fumigatus	50.10	8.00e-135	474.00
IUUC-Ani-009471	Aspergillus nidulans	50.30	3.00e-135	475.00
IUUC-Ang-009711	Aspergillus niger	50.31	4.00e-133	468.00
IUUC-Aor-010118	Aspergillus oryzae	50.41	1.00e-134	473.00
IUUC-Ate-010534	Aspergillus terreus	49.80	2.00e-134	473.00
IUUC-Ame-011011	Astyanax mexicanus	94.57	0.00e+00	912.00
IUUC-Bgr-012013	Blumeria graminis	47.89	2.00e-132	466.00
IUUC-Bta-012586	Bos taurus	94.95	0.00e+00	966.00
IUUC-Bci-013807	Botrytis cinerea	51.29	2.00e-128	452.00
IUUC-Bdi-014981	Brachypodium distachyon	71.15	2.00e-130	458.00
IUUC-Bol-016301	Brassica oleracea	56.39	5.00e-140	491.00
IUUC-Bra-017453	Brassica rapa	56.39	4.00e-140	491.00
IUUC-Cel-018472	Caenorhabditis elegans	65.52	5.00e-144	504.00
IUUC-Cja-019929	Callithrix jacchus	93.78	0.00e+00	957.00
IUUC-Cfa-020977	Canis familiaris	93.78	0.00e+00	957.00
IUUC-Cpo-021537	Cavia porcellus	94.55	0.00e+00	964.00
IUUC-Csa-023389	Chlorocebus sabaeus	94.14	0.00e+00	961.00
IUUC-Cin-025327	Ciona intestinalis	68.47	0.00e+00	632.00
IUUC-Csv-025921	Ciona savignyi	66.86	0.00e+00	678.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	49.62	2.00e-133	469.00
IUUC-Cne-026933	Cryptococcus neoformans	58.90	1.00e-127	450.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.37	2.00e-117	417.00
IUUC-Dre-027470	Danio rerio	93.95	0.00e+00	910.00
IUUC-Dno-029629	Dasypus novemcinctus	85.34	0.00e+00	784.00
IUUC-Dor-030187	Dipodomys ordii	84.54	0.00e+00	838.00
IUUC-Dse-031502	Dothistroma septosporum	50.00	7.00e-128	451.00
IUUC-Dme-031858	Drosophila melanogaster	70.45	0.00e+00	691.00
IUUC-Ete-032562	Echinops telfairi	82.42	0.00e+00	817.00
IUUC-Eca-034210	Equus caballus	94.14	0.00e+00	961.00
IUUC-Fca-035839	Felis catus	89.49	0.00e+00	895.00
IUUC-Fal-036895	Ficedula albicollis	95.76	0.00e+00	975.00
IUUC-Fso-038420	Fusarium solani	50.20	3.00e-133	469.00
IUUC-Gmo-039544	Gadus morhua	92.15	0.00e+00	889.00
IUUC-Ggr-039774	Gaeumannomyces graminis	51.08	2.00e-133	469.00
IUUC-Gga-041025	Gallus gallus	95.35	0.00e+00	971.00
IUUC-Gac-041596	Gasterosteus aculeatus	92.94	0.00e+00	905.00
IUUC-Gma-042657	Glycine max	56.50	9.00e-136	476.00
IUUC-Ggo-045599	Gorilla gorilla	93.78	0.00e+00	922.00
IUUC-Hsa-046695	Homo sapiens	93.57	0.00e+00	956.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	7.00e-107	379.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	93.33	0.00e+00	956.00
IUUC-Kpa-049239	Komagataella pastoris	46.08	4.00e-125	441.00
IUUC-Lch-049827	Latimeria chalumnae	95.76	0.00e+00	942.00
IUUC-Lpe-051568	Leersia perrieri	50.89	7.00e-112	397.00
IUUC-Laf-054321	Loxodonta africana	59.84	3.00e-148	518.00
IUUC-Mcc-055601	Macaca mulatta	94.14	0.00e+00	961.00
IUUC-Meu-056276	Macropus eugenii	67.93	3.00e-174	604.00
IUUC-Mor-057113	Magnaporthe oryzae	50.89	2.00e-133	469.00
IUUC-Mpo-057599	Magnaporthe poae	51.18	1.00e-133	470.00
IUUC-Mtr-057689	Medicago truncatula	56.77	1.00e-137	482.00
IUUC-Mla-059048	Melampsora laricipopulina	49.90	3.00e-121	428.00
IUUC-Mga-060097	Meleagris gallopavo	89.38	0.00e+00	898.00
IUUC-Mvi-060465	Microbotryum violaceum	51.60	1.00e-131	463.00
IUUC-Mmr-061151	Microcebus murinus	84.74	0.00e+00	826.00
IUUC-Mdo-063062	Monodelphis domestica	95.15	0.00e+00	970.00
IUUC-Mmu-063731	Mus musculus	94.55	0.00e+00	962.00
IUUC-Mac-065208	Musa acuminata	58.03	5.00e-130	457.00
IUUC-Mpu-066173	Mustela putorius furo	94.14	0.00e+00	961.00
IUUC-Mlu-068030	Myotis lucifugus	94.18	0.00e+00	959.00
IUUC-Nfi-068536	Neosartorya fischeri	50.00	2.00e-135	476.00
IUUC-Ncr-068734	Neurospora crassa	52.77	5.00e-137	481.00
IUUC-Nle-070163	Nomascus leucogenys	94.14	0.00e+00	962.00
IUUC-Opr-070974	Ochotona princeps	92.12	3.00e-155	540.00
IUUC-Ont-072272	Oreochromis niloticus	92.00	0.00e+00	897.00
IUUC-Oan-073634	Ornithorhynchus anatinus	98.63	2.00e-174	604.00
IUUC-Oba-075417	Oryza barthii	62.86	5.00e-111	394.00
IUUC-Obr-076123	Oryza brachyantha	57.95	1.00e-127	450.00
IUUC-Ogl-077294	Oryza glaberrima	54.30	4.00e-128	451.00
IUUC-Ogu-077996	Oryza glumaepatula	54.30	7.00e-127	447.00
IUUC-Oin-080172	Oryza indica	70.49	4.00e-127	447.00
IUUC-Olo-081068	Oryza longistaminata	70.49	4.00e-127	447.00
IUUC-Ome-081250	Oryza meridionalis	54.87	7.00e-129	454.00
IUUC-Oni-083048	Oryza nivara	54.30	4.00e-128	451.00
IUUC-Opu-083333	Oryza punctata	54.65	3.00e-128	452.00
IUUC-Oru-085001	Oryza rufipogon	54.30	4.00e-128	451.00
IUUC-Osa-086243	Oryza sativa	54.30	4.00e-128	451.00
IUUC-Ola-087094	Oryzias latipes	91.42	0.00e+00	855.00
IUUC-Oga-088911	Otolemur garnettii	94.55	0.00e+00	963.00
IUUC-Oar-089508	Ovis aries	94.95	0.00e+00	966.00
IUUC-Ptr-090967	Pan troglodytes	80.56	0.00e+00	630.00
IUUC-Pan-092147	Papio anubis	93.57	0.00e+00	956.00
IUUC-Psi-093702	Pelodiscus sinensis	94.97	0.00e+00	967.00
IUUC-Pma-094581	Petromyzon marinus	83.10	0.00e+00	813.00
IUUC-Pno-095139	Phaeosphaeria nodorum	60.06	7.00e-114	404.00
IUUC-Ppa-095366	Physcomitrella patens	58.07	6.00e-141	494.00
IUUC-Pfo-096309	Poecilia formosa	92.74	0.00e+00	903.00
IUUC-Pab-098762	Pongo abelii	76.91	0.00e+00	735.00
IUUC-Pop-098924	Populus trichocarpa	56.85	2.00e-132	465.00
IUUC-Pca-100565	Procavia capensis	90.04	0.00e+00	866.00
IUUC-Ppe-101924	Prunus persica	54.70	2.00e-137	482.00
IUUC-Pva-102602	Pteropus vampyrus	92.15	0.00e+00	919.00
IUUC-Pgr-103466	Puccinia graminis	51.07	2.00e-120	426.00
IUUC-Ptt-103888	Puccinia triticina	53.96	7.00e-108	384.00
IUUC-Pte-104097	Pyrenophora teres	49.53	5.00e-133	468.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	45.73	5.00e-116	411.00
IUUC-Rno-105028	Rattus norvegicus	94.34	0.00e+00	959.00
IUUC-Sce-106240	Saccharomyces cerevisiae	48.55	6.00e-95	341.00
IUUC-Sha-107107	Sarcophilus harrisii	81.08	0.00e+00	807.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	48.43	2.00e-116	412.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.62	1.00e-114	406.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	51.81	7.00e-131	460.00
IUUC-Smo-108878	Selaginella moellendorffii	57.69	5.00e-147	514.00
IUUC-Sit-110563	Setaria italica	53.58	3.00e-122	431.00
IUUC-Sly-111446	Solanum lycopersicum	55.02	7.00e-136	477.00
IUUC-Stu-112491	Solanum tuberosum	54.83	4.00e-135	474.00
IUUC-Sar-112962	Sorex araneus	79.39	1.00e-118	418.00
IUUC-Sbi-114489	Sorghum bicolor	54.08	2.00e-124	439.00
IUUC-Sre-115222	Sporisorium reilianum	48.20	3.00e-134	472.00
IUUC-Ssc-116171	Sus scrofa	94.95	0.00e+00	966.00
IUUC-Tgu-116878	Taeniopygia guttata	84.29	0.00e+00	834.00
IUUC-Tru-118222	Takifugu rubripes	91.38	0.00e+00	891.00
IUUC-Tni-119863	Tetraodon nigroviridis	92.14	0.00e+00	892.00
IUUC-Tca-121599	Theobroma cacao	58.01	1.00e-134	473.00
IUUC-Tre-122249	Trichoderma reesei	50.99	1.00e-134	473.00
IUUC-Tvi-122675	Trichoderma virens	51.48	2.00e-134	472.00
IUUC-Tae-123489	Triticum aestivum	53.71	1.00e-129	456.00
IUUC-Tur-126545	Triticum urartu	59.94	5.00e-104	370.00
IUUC-Tme-127151	Tuber melanosporum	53.83	2.00e-146	512.00
IUUC-Tbe-128056	Tupaia belangeri	87.50	3.00e-165	573.00
IUUC-Ttr-129055	Tursiops truncatus	93.57	0.00e+00	947.00
IUUC-Uma-129555	Ustilago maydis	48.02	3.00e-133	468.00
IUUC-Vda-130027	Verticillium dahliae	51.00	3.00e-135	475.00
IUUC-Vvi-131749	Vitis vinifera	55.21	2.00e-135	475.00
IUUC-Xtr-132808	Xenopus tropicalis	90.51	0.00e+00	923.00
IUUC-Xma-133183	Xiphophorus maculatus	92.74	0.00e+00	903.00
IUUC-Yli-134584	Yarrowia lipolytica	62.47	5.00e-132	464.00
IUUC-Zma-135262	Zea mays	54.95	4.00e-124	438.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence