iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	19882662

Reviewed

Classification

Family	Identity	E-value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	24.75	2.00e-10	62.40	IUUC-Spo-108289

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Targets AAH1 adenine deaminase for proteasome-dependent degradation upon entry into quiescence. Targets also URA7.

Protein Sequence
(Fasta)

MSEVESREKE PDAGLSPDIV QATLPFLSSD DIKNLSQTNK YYNTLLDFDH SKILWHELFH 60
KAFGTLKTND EPFQGRNSAE FKTCTETILR EAFPTLSWQE VYQLRAYDAK FYSWGYLKHG 120

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Nucleotide Sequence
(Fasta)

ATGAGTGAAG TTGAGAGCAG AGAAAAGGAG CCTGACGCAG GATTGTCCCC AGATATCGTT 60
CAAGCTACGC TACCATTTTT AAGCAGTGAT GATATTAAGA ACCTCTCGCA GACAAATAAG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS00626--RCC1_2
PS50012--RCC1_3

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

sce:YBR280C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000696	Aegilops tauschii	42.42	8.70e-02	31.20
IUUC-Ago-007818	Ashbya gossypii	41.51	2.00e-150	524.00
IUUC-Acl-008353	Aspergillus clavatus	54.05	1.00e-03	38.10
IUUC-Afl-008409	Aspergillus flavus	51.28	4.00e-04	39.30
IUUC-Afu-008944	Aspergillus fumigatus	47.22	2.00e-02	33.90
IUUC-Ani-009309	Aspergillus nidulans	51.28	7.00e-04	38.50
IUUC-Ang-009872	Aspergillus niger	50.00	3.00e-04	39.70
IUUC-Aor-010054	Aspergillus oryzae	51.28	3.00e-04	39.70
IUUC-Bdi-014094	Brachypodium distachyon	45.45	1.90e-02	33.10
IUUC-Cel-018177	Caenorhabditis elegans	19.58	3.00e-05	40.40
IUUC-Cre-023014	Chlamydomonas reinhardtii	51.85	3.00e-02	30.80
IUUC-Cne-026881	Cryptococcus neoformans	20.72	3.00e-07	48.50
IUUC-Dse-031320	Dothistroma septosporum	25.00	3.00e-07	48.50
IUUC-Ete-032687	Echinops telfairi	22.59	1.00e-03	39.70
IUUC-Fox-037821	Fusarium oxysporum	33.33	3.40e-02	32.70
IUUC-Ggr-040105	Gaeumannomyces graminis	40.74	4.10e-01	29.30
IUUC-Kpa-049110	Komagataella pastoris	27.29	1.00e-51	195.00
IUUC-Lma-053292	Leptosphaeria maculans	25.27	1.00e-13	69.70
IUUC-Mor-057268	Magnaporthe oryzae	23.73	2.00e-07	48.50
IUUC-Mtr-058718	Medicago truncatula	33.33	4.00e-03	35.40
IUUC-Mla-058948	Melampsora laricipopulina	30.00	2.00e-04	40.00
IUUC-Mac-065442	Musa acuminata	36.96	1.00e-03	37.40
IUUC-Nfi-068585	Neosartorya fischeri	48.65	9.00e-03	35.00
IUUC-Ncr-068789	Neurospora crassa	44.44	2.90e-01	29.60
IUUC-Obr-076115	Oryza brachyantha	37.29	4.00e-03	33.90
IUUC-Oin-079298	Oryza indica	36.21	1.60e-02	32.00
IUUC-Oni-082049	Oryza nivara	36.21	1.70e-02	32.00
IUUC-Olu-087836	Ostreococcus lucimarinus	42.11	3.50e-02	30.40
IUUC-Pma-094275	Petromyzon marinus	48.65	1.30e-02	33.90
IUUC-Pno-094797	Phaeosphaeria nodorum	23.19	3.00e-12	64.30
IUUC-Ppa-095790	Physcomitrella patens	57.14	3.00e-04	38.10
IUUC-Pfo-096208	Poecilia formosa	24.82	4.00e-03	37.40
IUUC-Pgr-103585	Puccinia graminis	21.19	3.00e-06	45.10
IUUC-Ptt-103896	Puccinia triticina	21.85	5.00e-07	47.40
IUUC-Pte-104072	Pyrenophora teres	25.36	5.00e-14	70.90
IUUC-Pyt-104521	Pyrenophora triticirepentis	25.57	5.00e-12	63.90
IUUC-Sja-107740	Schizosaccharomyces japonicus	44.44	6.00e-03	35.00
IUUC-Spo-108289	Schizosaccharomyces pombe	24.75	1.00e-11	62.00
IUUC-Ssl-108511	Sclerotinia sclerotiorum	24.10	8.70e-02	30.00
IUUC-Sre-115110	Sporisorium reilianum	31.87	4.00e-05	41.20
IUUC-Uma-129630	Ustilago maydis	23.65	3.00e-03	35.00
IUUC-Vda-129791	Verticillium dahliae	44.44	1.50e-01	30.80
IUUC-Yli-134679	Yarrowia lipolytica	33.10	9.00e-33	132.00
IUUC-Zma-135450	Zea mays	45.45	6.50e-02	31.20

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence