iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094535

UUCD1 version

UUC-PeM-00262

Ensembl Protein ID

ENSPMAP00000002494.1

UniProt Accession

S4RBB3; S4RBB3_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000002224.1	ENSPMAT00000002506.1	ENSPMAP00000002494.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-45	147.9	146	183
UBD/Beta-Prp	3.40e-54	183.2	10	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgv 34
           gHt++v+c++f   ++ +++vs+++D+ +kvW+l+ ++
   Q: 146  GHTEWVSCVRFspnNNnPIIVSCGWDKLVKVWNLTNCK 183
           8***********98446****************99876 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv 87
           tlkgh+  v +  +  ++ ++++++srd+t++ w++t+  +      rsl gh  +v++v +s+dg++ ++gs D+t+++wdl tg+++
   Q: 10   TLKGHNGWVTQIATTPQFPDMILSASRDKTLIMWKLTRDETnygipQRSLHGHGHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT 98
           7788887776655559999*******************999************************************************ PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrt 174
           + + gh+++vls++fs+++  +vsGs+d+ti++w++    ++   ++gh+++v+cv+++p++   ++vs++ D+ v++W+l t++ l+t
   Q: 99   RRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQEDGHTEWVSCVRFSPNNnnPIIVSCGWDKLVKVWNL-TNCKLKT 186
           **********************************7765544444799*************996559***************.7777777 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
              ght++ + ++++++g  ++sg++dg+  lwdl +g+ ++tl g  d+++ + fs  + + ++++  +si+iWdl+ + ++
   Q: 187  NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DTINALCFS-PNRYWLCAATGPSIKIWDLEGKVIV 267
           7666****************************************997.568889999.7788889999********9976665 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTL IMWKLTRDET NYGIPQRSLH 60
GHGHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSADNRQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAGAGCG CTGAGCGCTC ACGCAGCAAT CCGCATCCAT CCGCGCGCTC CGAGCCGCCA 60
CCGCGCTTCA TCATGACGGA GCAGATGACC CTGCGCGGGA CCCTCAAGGG CCACAACGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001525--P:angiogenesis
GO:0060027--P:convergent extension involved in gastrulation
GO:0030178--P:negative regulation of Wnt signaling pathway
GO:2000543--P:positive regulation of gastrulation
GO:0051302--P:regulation of cell division
GO:2000114--P:regulation of establishment of cell polarity
GO:0032880--P:regulation of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	66.55	2.00e-105	373.00
IUUC-Aml-001935	Ailuropoda melanoleuca	94.01	0.00e+00	626.00
IUUC-Atr-002694	Amborella trichopoda	67.41	7.00e-124	434.00
IUUC-Apl-003918	Anas platyrhynchos	93.24	3.00e-159	552.00
IUUC-Aca-004869	Anolis carolinensis	94.01	0.00e+00	626.00
IUUC-Aly-005671	Arabidopsis lyrata	64.51	3.00e-124	436.00
IUUC-Ath-007105	Arabidopsis thaliana	65.63	1.00e-124	437.00
IUUC-Ago-007720	Ashbya gossypii	56.87	7.00e-104	368.00
IUUC-Acl-008156	Aspergillus clavatus	73.40	4.00e-139	485.00
IUUC-Afl-008684	Aspergillus flavus	72.44	3.00e-138	483.00
IUUC-Afu-008867	Aspergillus fumigatus	74.68	3.00e-141	492.00
IUUC-Ani-009221	Aspergillus nidulans	73.40	1.00e-139	487.00
IUUC-Ang-009843	Aspergillus niger	72.44	9.00e-138	481.00
IUUC-Aor-010193	Aspergillus oryzae	72.44	3.00e-138	483.00
IUUC-Ate-010420	Aspergillus terreus	73.85	4.00e-126	442.00
IUUC-Ame-010884	Astyanax mexicanus	94.32	0.00e+00	629.00
IUUC-Bgr-012064	Blumeria graminis	72.44	2.00e-138	483.00
IUUC-Bta-013357	Bos taurus	94.01	0.00e+00	626.00
IUUC-Bci-013862	Botrytis cinerea	73.08	3.00e-140	489.00
IUUC-Bdi-014690	Brachypodium distachyon	63.00	9.00e-114	401.00
IUUC-Bol-016231	Brassica oleracea	65.94	2.00e-126	443.00
IUUC-Bra-016879	Brassica rapa	65.53	3.00e-125	439.00
IUUC-Cel-018335	Caenorhabditis elegans	70.94	8.00e-125	438.00
IUUC-Cja-019914	Callithrix jacchus	94.01	0.00e+00	626.00
IUUC-Cfa-020755	Canis familiaris	94.01	0.00e+00	626.00
IUUC-Cpo-022377	Cavia porcellus	94.01	0.00e+00	628.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	75.56	1.00e-137	480.00
IUUC-Csa-023025	Chlorocebus sabaeus	94.01	0.00e+00	626.00
IUUC-Cin-025647	Ciona intestinalis	78.98	2.00e-149	520.00
IUUC-Csv-026027	Ciona savignyi	78.66	2.00e-147	513.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	75.62	7.00e-130	454.00
IUUC-Cne-026930	Cryptococcus neoformans	72.44	4.00e-138	482.00
IUUC-Cme-027251	Cyanidioschyzon merolae	65.06	4.00e-124	436.00
IUUC-Dre-028669	Danio rerio	94.01	0.00e+00	626.00
IUUC-Dno-029470	Dasypus novemcinctus	80.13	6.00e-144	501.00
IUUC-Dor-031098	Dipodomys ordii	83.96	1.00e-142	497.00
IUUC-Dse-031255	Dothistroma septosporum	73.40	3.00e-140	489.00
IUUC-Dme-032118	Drosophila melanogaster	78.73	4.00e-150	522.00
IUUC-Ete-033182	Echinops telfairi	78.03	4.00e-101	359.00
IUUC-Eca-033296	Equus caballus	92.67	2.00e-83	298.00
IUUC-Eeu-034771	Erinaceus europaeus	89.59	2.00e-170	589.00
IUUC-Fca-036315	Felis catus	94.01	0.00e+00	626.00
IUUC-Fal-036990	Ficedula albicollis	90.56	1.00e-98	350.00
IUUC-Fox-037702	Fusarium oxysporum	74.68	1.00e-142	497.00
IUUC-Fso-038384	Fusarium solani	75.32	6.00e-143	498.00
IUUC-Gmo-039630	Gadus morhua	91.56	1.00e-172	597.00
IUUC-Ggr-039985	Gaeumannomyces graminis	74.36	2.00e-142	496.00
IUUC-Gga-040540	Gallus gallus	94.01	0.00e+00	626.00
IUUC-Gac-041316	Gasterosteus aculeatus	90.68	4.00e-173	598.00
IUUC-Gma-042872	Glycine max	64.91	8.00e-124	434.00
IUUC-Ggo-045253	Gorilla gorilla	94.01	0.00e+00	626.00
IUUC-Hsa-046809	Homo sapiens	94.01	0.00e+00	626.00
IUUC-Hvu-047683	Hordeum vulgare	63.53	3.00e-115	406.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	94.01	0.00e+00	626.00
IUUC-Kpa-049214	Komagataella pastoris	58.06	8.00e-101	358.00
IUUC-Lch-049634	Latimeria chalumnae	93.06	2.00e-179	619.00
IUUC-Lpe-050763	Leersia perrieri	62.39	7.00e-113	398.00
IUUC-Loc-052163	Lepisosteus oculatus	94.95	0.00e+00	630.00
IUUC-Lma-053113	Leptosphaeria maculans	74.04	2.00e-141	493.00
IUUC-Laf-054422	Loxodonta africana	94.01	0.00e+00	626.00
IUUC-Mcc-055348	Macaca mulatta	94.01	0.00e+00	626.00
IUUC-Meu-056543	Macropus eugenii	94.01	0.00e+00	627.00
IUUC-Mor-057107	Magnaporthe oryzae	74.36	3.00e-142	495.00
IUUC-Mpo-057487	Magnaporthe poae	74.68	5.00e-143	498.00
IUUC-Mtr-058808	Medicago truncatula	65.22	2.00e-124	436.00
IUUC-Mla-058909	Melampsora laricipopulina	72.52	1.00e-138	483.00
IUUC-Mga-059387	Meleagris gallopavo	94.01	0.00e+00	626.00
IUUC-Mvi-060392	Microbotryum violaceum	70.51	2.00e-136	476.00
IUUC-Mmr-061141	Microcebus murinus	83.74	7.00e-133	464.00
IUUC-Mdo-062932	Monodelphis domestica	94.01	0.00e+00	626.00
IUUC-Mmu-064132	Mus musculus	94.01	0.00e+00	626.00
IUUC-Mac-064447	Musa acuminata	61.11	2.00e-108	384.00
IUUC-Mpu-066721	Mustela putorius furo	93.06	5.00e-178	615.00
IUUC-Mlu-068221	Myotis lucifugus	93.38	1.00e-169	587.00
IUUC-Nfi-068344	Neosartorya fischeri	74.68	3.00e-141	492.00
IUUC-Ncr-068722	Neurospora crassa	73.40	1.00e-140	490.00
IUUC-Nle-069865	Nomascus leucogenys	94.01	0.00e+00	627.00
IUUC-Opr-071100	Ochotona princeps	79.50	1.00e-145	507.00
IUUC-Ont-072287	Oreochromis niloticus	93.38	3.00e-180	622.00
IUUC-Oan-072788	Ornithorhynchus anatinus	94.01	0.00e+00	626.00
IUUC-Ocu-073844	Oryctolagus cuniculus	91.80	2.00e-175	606.00
IUUC-Oba-075981	Oryza barthii	60.56	6.00e-103	365.00
IUUC-Obr-076099	Oryza brachyantha	61.77	8.00e-113	398.00
IUUC-Ogl-077804	Oryza glaberrima	63.00	8.00e-115	405.00
IUUC-Ogu-078035	Oryza glumaepatula	63.69	4.00e-114	402.00
IUUC-Oin-079327	Oryza indica	63.69	4.00e-114	402.00
IUUC-Olo-081084	Oryza longistaminata	63.69	4.00e-114	402.00
IUUC-Ome-081366	Oryza meridionalis	63.30	4.00e-115	406.00
IUUC-Oni-082682	Oryza nivara	63.30	4.00e-115	406.00
IUUC-Opu-084010	Oryza punctata	63.30	2.00e-115	407.00
IUUC-Oru-084358	Oryza rufipogon	63.30	4.00e-115	406.00
IUUC-Osa-085296	Oryza sativa	63.30	4.00e-115	406.00
IUUC-Ola-086400	Oryzias latipes	93.06	8.00e-180	620.00
IUUC-Olu-087817	Ostreococcus lucimarinus	76.10	2.00e-142	496.00
IUUC-Oga-088811	Otolemur garnettii	94.01	0.00e+00	626.00
IUUC-Oar-089962	Ovis aries	94.01	0.00e+00	626.00
IUUC-Ptr-091340	Pan troglodytes	94.01	0.00e+00	626.00
IUUC-Pan-091946	Papio anubis	94.01	0.00e+00	626.00
IUUC-Pno-095100	Phaeosphaeria nodorum	76.89	2.00e-98	350.00
IUUC-Ppa-095752	Physcomitrella patens	76.36	2.00e-141	493.00
IUUC-Pfo-097311	Poecilia formosa	93.06	3.00e-180	622.00
IUUC-Pab-097863	Pongo abelii	94.01	0.00e+00	627.00
IUUC-Pop-099345	Populus trichocarpa	67.49	1.00e-127	447.00
IUUC-Pca-100594	Procavia capensis	93.06	1.00e-179	620.00
IUUC-Ppe-101743	Prunus persica	64.81	1.00e-122	431.00
IUUC-Pva-102746	Pteropus vampyrus	78.86	1.00e-143	501.00
IUUC-Pgr-103375	Puccinia graminis	54.31	5.00e-94	335.00
IUUC-Ptt-103839	Puccinia triticina	71.57	3.00e-135	472.00
IUUC-Pte-104026	Pyrenophora teres	74.04	2.00e-141	493.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	74.04	3.00e-141	493.00
IUUC-Rno-104964	Rattus norvegicus	94.01	0.00e+00	626.00
IUUC-Sce-106224	Saccharomyces cerevisiae	55.10	1.00e-99	354.00
IUUC-Sha-107409	Sarcophilus harrisii	94.01	0.00e+00	626.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	66.45	5.00e-128	448.00
IUUC-Spo-108297	Schizosaccharomyces pombe	63.90	2.00e-123	433.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	73.08	3.00e-140	489.00
IUUC-Smo-109017	Selaginella moellendorffii	69.94	8.00e-128	448.00
IUUC-Sit-110060	Setaria italica	64.00	2.00e-116	410.00
IUUC-Sly-111496	Solanum lycopersicum	68.12	2.00e-127	446.00
IUUC-Stu-112757	Solanum tuberosum	66.88	1.00e-123	434.00
IUUC-Sar-113173	Sorex araneus	94.01	0.00e+00	626.00
IUUC-Sbi-114681	Sorghum bicolor	63.69	2.00e-116	410.00
IUUC-Sre-115107	Sporisorium reilianum	71.15	2.00e-140	490.00
IUUC-Ssc-116218	Sus scrofa	89.59	5.00e-173	598.00
IUUC-Tru-118202	Takifugu rubripes	92.43	3.00e-178	615.00
IUUC-Tni-120260	Tetraodon nigroviridis	91.48	4.00e-177	611.00
IUUC-Tca-120951	Theobroma cacao	65.53	2.00e-125	440.00
IUUC-Tre-121961	Trichoderma reesei	74.68	8.00e-142	494.00
IUUC-Tvi-122447	Trichoderma virens	74.68	5.00e-142	495.00
IUUC-Tae-123560	Triticum aestivum	63.53	3.00e-115	406.00
IUUC-Tur-126335	Triticum urartu	68.52	9.00e-105	371.00
IUUC-Tme-127105	Tuber melanosporum	69.26	7.00e-127	444.00
IUUC-Tbe-128021	Tupaia belangeri	75.74	1.00e-83	300.00
IUUC-Ttr-128637	Tursiops truncatus	82.65	1.00e-155	540.00
IUUC-Uma-129634	Ustilago maydis	72.12	3.00e-141	492.00
IUUC-Vda-129923	Verticillium dahliae	74.04	2.00e-141	493.00
IUUC-Vpa-130410	Vicugna pacos	73.75	5.00e-108	382.00
IUUC-Vvi-131115	Vitis vinifera	65.43	3.00e-126	442.00
IUUC-Xtr-132105	Xenopus tropicalis	93.38	0.00e+00	625.00
IUUC-Xma-133875	Xiphophorus maculatus	92.74	2.00e-179	619.00
IUUC-Yli-134624	Yarrowia lipolytica	62.03	4.00e-120	422.00
IUUC-Zma-134711	Zea mays	63.38	1.00e-114	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence