iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004880

UUCD1 version

UUC-AnC-00252

Ensembl Protein ID

ENSACAP00000005864.2

UniProt Accession

H9GAT7; H9GAT7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005963.3	ENSACAT00000005993.3	ENSACAP00000005864.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-43	144.3	230	269
UBD/Beta-Prp	5.30e-74	249.0	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d  ++vs+s D+t+kvWD+ + +++++
   Q: 230  GHASWVLNVAFcPDnSHFVSSSSDKTVKVWDVPSRTCVHT 269
           8***********888*****************99999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    s++++ +++gs d+ +kvw + ++kl   ++l+gh+ +v +v++s++g + +++s D++i++wdl++gk+++
   Q: 12   EQAHDDAIWSVAWgrnrSDGTETVISGSLDDLVKVWTWNEEKLdlKWTLEGHQLGVVSVDISHTGTVAASSSLDAHIRIWDLDSGKQIR 100
           56788888889999999999**********************9999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   +++sl+fsp+++++++Gsh   ++++ +etg++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWSLAFSPDSQYVATGSHIGKVNIFGVETGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p++ ++vs ssD+++++Wd+ s+++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDNSHFVSSSSDKTVKVWDVPSRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++++++
   Q: 277  VWGVQY-NGNGSKIVSVGDDQEIHVYDC 303
           ******.999****************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MTTQYSILFK QEQAHDDAIW SVAWGRNRSD GTETVISGSL DDLVKVWTWN EEKLDLKWTL 60
EGHQLGVVSV DISHTGTVAA SSSLDAHIRI WDLDSGKQIR SIDAGPVDAW SLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAAGAGCG TTCAGCTGTT CTTCTCTATG GAAAAAAAGG GCGCTCTGGT TATGACGTCA 60
TTAGAAAGCG CCGGAAGCGC CAAGCAGGAG GTAGAGTGGC CGTGGGTGAA ACCTTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

acs:100565531

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.73	1.00e-51	196.00
IUUC-Aml-002245	Ailuropoda melanoleuca	89.18	9.00e-156	542.00
IUUC-Atr-003142	Amborella trichopoda	52.17	8.00e-43	166.00
IUUC-Apl-003179	Anas platyrhynchos	89.18	2.00e-157	547.00
IUUC-Aly-005956	Arabidopsis lyrata	38.98	2.00e-61	228.00
IUUC-Ath-007230	Arabidopsis thaliana	37.50	6.00e-56	210.00
IUUC-Acl-008297	Aspergillus clavatus	27.80	1.00e-28	120.00
IUUC-Ame-011511	Astyanax mexicanus	82.41	4.00e-150	523.00
IUUC-Bgr-012189	Blumeria graminis	30.35	1.00e-34	139.00
IUUC-Bta-012936	Bos taurus	88.85	1.00e-155	541.00
IUUC-Bdi-015020	Brachypodium distachyon	37.88	1.00e-51	196.00
IUUC-Bol-015927	Brassica oleracea	39.62	7.00e-62	230.00
IUUC-Bra-017323	Brassica rapa	39.30	1.00e-61	229.00
IUUC-Cja-019961	Callithrix jacchus	88.20	7.00e-155	539.00
IUUC-Cfa-020862	Canis familiaris	89.51	9.00e-156	542.00
IUUC-Cpo-021356	Cavia porcellus	88.41	1.00e-153	535.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.91	2.00e-60	225.00
IUUC-Csa-024067	Chlorocebus sabaeus	87.87	3.00e-154	536.00
IUUC-Cho-024421	Choloepus hoffmanni	77.27	6.00e-79	286.00
IUUC-Cin-025261	Ciona intestinalis	65.90	6.00e-125	439.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	27.99	9.00e-33	133.00
IUUC-Cne-026846	Cryptococcus neoformans	27.87	7.00e-25	107.00
IUUC-Dre-027706	Danio rerio	63.93	4.00e-112	397.00
IUUC-Dno-029084	Dasypus novemcinctus	87.95	1.00e-153	535.00
IUUC-Dor-030353	Dipodomys ordii	74.64	2.00e-117	414.00
IUUC-Dse-031348	Dothistroma septosporum	30.08	3.00e-30	125.00
IUUC-Dme-031836	Drosophila melanogaster	52.00	2.00e-94	338.00
IUUC-Ete-032261	Echinops telfairi	86.56	3.00e-150	523.00
IUUC-Eca-034231	Equus caballus	81.64	1.00e-140	491.00
IUUC-Eeu-034828	Erinaceus europaeus	87.63	4.00e-144	503.00
IUUC-Fca-036569	Felis catus	88.85	3.00e-155	540.00
IUUC-Fal-037469	Ficedula albicollis	91.80	2.00e-162	563.00
IUUC-Fox-038047	Fusarium oxysporum	33.11	4.00e-34	138.00
IUUC-Gmo-039579	Gadus morhua	83.61	5.00e-149	520.00
IUUC-Gga-040808	Gallus gallus	91.10	1.00e-153	535.00
IUUC-Gac-042100	Gasterosteus aculeatus	83.93	1.00e-149	521.00
IUUC-Gma-044408	Glycine max	41.35	1.00e-64	239.00
IUUC-Ggo-045227	Gorilla gorilla	88.20	7.00e-155	539.00
IUUC-Hsa-045839	Homo sapiens	88.20	7.00e-155	539.00
IUUC-Hvu-047591	Hordeum vulgare	38.68	2.00e-54	206.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	88.52	2.00e-155	540.00
IUUC-Lch-049549	Latimeria chalumnae	81.31	7.00e-150	522.00
IUUC-Lpe-050746	Leersia perrieri	38.91	9.00e-53	200.00
IUUC-Loc-052540	Lepisosteus oculatus	85.25	1.00e-149	521.00
IUUC-Lma-052992	Leptosphaeria maculans	28.23	3.00e-30	125.00
IUUC-Laf-053907	Loxodonta africana	88.52	2.00e-155	540.00
IUUC-Mcc-055828	Macaca mulatta	82.46	1.00e-150	525.00
IUUC-Meu-056075	Macropus eugenii	90.59	2.00e-132	464.00
IUUC-Mor-056971	Magnaporthe oryzae	26.82	1.00e-27	116.00
IUUC-Mtr-057728	Medicago truncatula	41.03	3.00e-62	231.00
IUUC-Mga-059872	Meleagris gallopavo	91.15	2.00e-161	561.00
IUUC-Mvi-060564	Microbotryum violaceum	31.54	1.00e-34	140.00
IUUC-Mmr-060985	Microcebus murinus	88.70	4.00e-148	516.00
IUUC-Mdo-062758	Monodelphis domestica	87.83	1.00e-155	541.00
IUUC-Mmu-063580	Mus musculus	87.54	9.00e-154	535.00
IUUC-Mac-064880	Musa acuminata	40.84	2.00e-62	232.00
IUUC-Mpu-066577	Mustela putorius furo	88.85	1.00e-154	538.00
IUUC-Nle-069573	Nomascus leucogenys	88.20	7.00e-155	539.00
IUUC-Opr-070216	Ochotona princeps	89.37	7.00e-154	536.00
IUUC-Ont-071981	Oreochromis niloticus	82.62	2.00e-149	521.00
IUUC-Oan-073223	Ornithorhynchus anatinus	92.50	9.00e-109	385.00
IUUC-Ocu-074199	Oryctolagus cuniculus	76.07	4.00e-128	450.00
IUUC-Oba-075255	Oryza barthii	40.77	2.00e-46	179.00
IUUC-Obr-076168	Oryza brachyantha	47.20	2.00e-39	155.00
IUUC-Ogl-077777	Oryza glaberrima	38.46	7.00e-53	200.00
IUUC-Ogu-078780	Oryza glumaepatula	38.46	7.00e-53	200.00
IUUC-Oin-079228	Oryza indica	38.71	2.00e-55	209.00
IUUC-Olo-080617	Oryza longistaminata	45.77	5.00e-33	132.00
IUUC-Ome-081421	Oryza meridionalis	38.71	5.00e-52	197.00
IUUC-Oni-082997	Oryza nivara	38.71	2.00e-55	209.00
IUUC-Opu-083931	Oryza punctata	39.74	2.00e-53	202.00
IUUC-Oru-084645	Oryza rufipogon	38.46	7.00e-53	200.00
IUUC-Osa-085842	Oryza sativa	38.71	2.00e-55	209.00
IUUC-Ola-086696	Oryzias latipes	83.61	3.00e-147	513.00
IUUC-Olu-087643	Ostreococcus lucimarinus	38.97	4.00e-45	174.00
IUUC-Oga-088272	Otolemur garnettii	88.49	2.00e-153	535.00
IUUC-Oar-089416	Ovis aries	88.85	1.00e-155	541.00
IUUC-Ptr-090944	Pan troglodytes	88.20	7.00e-155	539.00
IUUC-Pan-091861	Papio anubis	88.20	7.00e-155	539.00
IUUC-Psi-093750	Pelodiscus sinensis	91.48	4.00e-162	563.00
IUUC-Pma-094608	Petromyzon marinus	79.03	1.00e-136	479.00
IUUC-Pno-094832	Phaeosphaeria nodorum	30.00	2.00e-29	122.00
IUUC-Ppa-095737	Physcomitrella patens	41.03	7.00e-62	230.00
IUUC-Pfo-096479	Poecilia formosa	83.93	5.00e-144	503.00
IUUC-Pab-098179	Pongo abelii	88.20	7.00e-155	539.00
IUUC-Pop-099532	Populus trichocarpa	40.91	8.00e-61	226.00
IUUC-Pca-100664	Procavia capensis	69.20	2.00e-97	347.00
IUUC-Ppe-102056	Prunus persica	39.94	3.00e-62	231.00
IUUC-Pva-102859	Pteropus vampyrus	88.52	2.00e-154	538.00
IUUC-Pte-104236	Pyrenophora teres	29.39	1.00e-28	120.00
IUUC-Rno-105826	Rattus norvegicus	87.21	5.00e-153	533.00
IUUC-Sha-106660	Sarcophilus harrisii	88.04	2.00e-148	517.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	31.91	2.00e-38	152.00
IUUC-Spo-108244	Schizosaccharomyces pombe	30.97	4.00e-38	151.00
IUUC-Smo-109234	Selaginella moellendorffii	44.15	2.00e-67	248.00
IUUC-Sit-110048	Setaria italica	38.14	4.00e-45	174.00
IUUC-Sly-111618	Solanum lycopersicum	38.78	5.00e-58	217.00
IUUC-Stu-112543	Solanum tuberosum	39.10	8.00e-61	226.00
IUUC-Sar-113743	Sorex araneus	70.16	3.00e-120	424.00
IUUC-Sbi-114309	Sorghum bicolor	39.52	2.00e-46	179.00
IUUC-Ssc-115560	Sus scrofa	83.93	2.00e-144	504.00
IUUC-Tgu-117300	Taeniopygia guttata	91.48	7.00e-162	562.00
IUUC-Tru-117933	Takifugu rubripes	84.59	1.00e-151	528.00
IUUC-Tsy-119574	Tarsius syrichta	77.70	2.00e-131	461.00
IUUC-Tni-120191	Tetraodon nigroviridis	85.23	9.00e-113	399.00
IUUC-Tca-120983	Theobroma cacao	40.45	3.00e-63	234.00
IUUC-Tae-124056	Triticum aestivum	37.18	7.00e-54	203.00
IUUC-Tur-126711	Triticum urartu	36.76	9.00e-53	200.00
IUUC-Tme-127066	Tuber melanosporum	33.09	1.00e-37	150.00
IUUC-Tbe-127802	Tupaia belangeri	88.85	3.00e-155	540.00
IUUC-Ttr-128861	Tursiops truncatus	86.51	5.00e-51	194.00
IUUC-Vda-129720	Verticillium dahliae	30.47	1.00e-26	113.00
IUUC-Vpa-130618	Vicugna pacos	84.74	2.00e-124	437.00
IUUC-Vvi-130981	Vitis vinifera	41.03	3.00e-61	228.00
IUUC-Xtr-132460	Xenopus tropicalis	85.57	3.00e-148	517.00
IUUC-Xma-134154	Xiphophorus maculatus	83.93	2.00e-144	504.00
IUUC-Zma-135097	Zea mays	36.69	2.00e-40	159.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence